Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_008559834.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053594616.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_008557640.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_008546516.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014295097.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_008550519.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_008551445.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_053598048.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_008548356.1 14 MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-5078;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5101;MetaCyc: PWY-7767 "L-leucine degradation III";"L-valine degradation II";"L-isoleucine degradation II";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)" XP_008544712.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053599023.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_008549133.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_008553265.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008548422.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_014296858.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_014298717.1 7 KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7210 "Purine metabolism";"UTP and CTP dephosphorylation I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_008547003.1 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation" XP_053596986.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008548149.2 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_008558146.1 9 MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367 "2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_008559225.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-389957 "Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_053595064.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008544795.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053597388.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14 "Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation" XP_053595492.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300 "Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors" XP_008557305.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008553042.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008559815.1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_008545576.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" XP_014295428.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008552636.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_008553858.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_008560123.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_053598547.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053594022.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008556805.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_008558803.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling" XP_053598837.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_008556056.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_008555752.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_053595430.1 7 KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_014298882.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_008548705.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_008559281.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053593327.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_008546080.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008545986.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_014300273.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014295321.2 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_008543817.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_053598182.1 10 Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_008557296.3 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008554557.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008558828.1 16 Reactome: R-HSA-164939;Reactome: R-HSA-190873;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8964038 "Nef mediated downregulation of CD28 cell surface expression";"Gap junction degradation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"LDL clearance" XP_053595446.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_053595220.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6 "(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism" XP_008549745.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008560108.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014295819.2 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis" XP_014294856.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053595810.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178 "Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans" XP_008543588.1 10 MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Glutathione metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism" XP_014300783.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_008558378.1 10 Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7661;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_053594988.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis" XP_053594156.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008556122.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_053596618.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_053595078.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_053597718.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_053598801.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_053594727.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_008557947.1 40 Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-203927 "HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_014296696.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_008543978.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008557036.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_008548257.1 29 Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_008559843.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs" XP_053593816.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014295730.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_008547469.1 6 MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)" XP_008546446.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008543326.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053593822.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_053596870.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_053594863.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_008549800.1 18 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7197 "Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation" XP_014298387.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083 "ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions" XP_053593226.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_053593440.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" NP_001401740.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_008550981.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014296747.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_008546810.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008558504.1 6 Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HDACs deacetylate histones";"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex" XP_014296096.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_008555032.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014294958.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008555176.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_014299575.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_008560499.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-6814122 "Neutrophil degranulation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Synthesis of PC";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_008559414.1 29 Reactome: R-HSA-5693565;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207;Reactome: R-HSA-5693579;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-912446;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804760 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human cytomegalovirus infection";"Human papillomavirus infection";"Stabilization of p53";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Homologous DNA Pairing and Strand Exchange";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Meiotic recombination";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Methylation" XP_053595678.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008543452.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_008560529.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_053595868.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053599072.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_008556441.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_053593959.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008546991.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_008548985.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_008553321.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_008545434.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_008546002.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_053599136.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008552195.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014299232.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008547481.1 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" XP_008545060.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_008547493.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_008556579.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008546966.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053594723.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008554455.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_053596355.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008561005.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_008547949.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008553743.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_008551332.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-373080 "Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Activation of SMO";"Class B/2 (Secretin family receptors)" XP_008545171.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008559847.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_008555553.3 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826 "Gamma-glutamyl cycle";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis" XP_053593960.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053597855.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053596513.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_053593984.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008545659.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_008550348.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_008549612.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_053597268.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053597784.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900 "Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4" XP_008554334.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_014296743.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_008561163.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014297643.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_053595966.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_008546111.1 6 KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_008558302.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_008559205.3 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;Reactome: R-HSA-1475029 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide" XP_008550032.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008553135.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008544968.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_008546179.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_008545987.2 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_053597039.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_008544045.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_008555733.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-8951664 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation" XP_014295093.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_008558774.1 5 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate" XP_008557992.2 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688 "Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Proline catabolism" XP_014300520.1 6 MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)" XP_008552499.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_053599027.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_008549137.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_014297459.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_008550657.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008553994.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014300682.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008561201.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_053596814.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008547374.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation" XP_014298299.1 14 Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-418217;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;Reactome: R-HSA-1855204;Reactome: R-HSA-399997;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"Synthesis of IP3 and IP4 in the cytosol";"Acetylcholine regulates insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule" XP_008553715.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053593067.1 9 MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351 "2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_014295431.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008550632.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008555113.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_008551476.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606 "Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_053594362.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)" XP_008559297.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_008546707.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_053598833.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014299592.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008551852.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_008554343.1 4 Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_008553819.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008547508.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_053599140.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014298133.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053594551.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483 "Gap junction assembly";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs" XP_053598445.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008546764.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174417 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis" XP_008556040.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014294836.1 5 KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_014300295.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008555946.1 32 Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-72086 "RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"mRNA Capping" XP_008548309.1 11 Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68952 "Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation" XP_008558917.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_008548163.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_008554488.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008544012.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_053598748.1 24 Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-163359 "Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation" XP_008554638.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_053594287.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_053594136.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_008550644.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" XP_053593217.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053597447.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014296742.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_008561162.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014297642.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_053595003.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_008557056.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_053593827.1 10 Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6317 "Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)" XP_008548186.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_014296909.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008549584.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008555487.1 25 Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-8955332 "Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"RHO GTPases Activate Formins";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin" XP_008551333.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922 "Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium" XP_053593763.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72702 "ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition" XP_008560511.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_008552898.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_053596512.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008545388.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_008557177.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_008557740.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008557942.1 3 KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041 "Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle" XP_008543490.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008548856.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_053595165.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008553742.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_008543520.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008546003.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014299233.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_014296358.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_053598240.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_008556009.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014295646.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008545481.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_053596904.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008554552.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_008546982.1 18 KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing" XP_008546780.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_053598236.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_008551853.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events" XP_008547119.2 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_008554342.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_008543812.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-168333 "SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_008559854.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_053599200.1 15 Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_014298132.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008559071.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053594363.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)" XP_008553796.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_053594109.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_008543376.1 14 MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8052 "Stigma estolide biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis" XP_014295480.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_008548336.1 10 MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5839;MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-5890;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5892 "Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis" XP_008555757.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_053597870.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053594027.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_008546450.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008550633.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008557404.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_008550491.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008549153.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation" XP_014296838.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008550975.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008555126.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014299495.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" NP_001401756.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_008547078.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014298723.2 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_053593456.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_008553761.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014297081.2 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_014300683.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014295030.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008553838.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008543787.1 25 Reactome: R-HSA-8951936;Reactome: R-HSA-8941326;Reactome: R-HSA-8939246;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8940973;Reactome: R-HSA-8939247;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8934593;Reactome: R-HSA-8951911;Reactome: R-HSA-8941333;Reactome: R-HSA-8931987;Reactome: R-HSA-8941858;Reactome: R-HSA-8936459;Reactome: R-HSA-8939242;Reactome: R-HSA-8949275;Reactome: R-HSA-8877330;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-8939243;Reactome: R-HSA-8939236;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8939256 "RUNX3 regulates p14-ARF";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX3 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in WNT signaling" XP_053594528.1 10 KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11 "Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_008547728.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008555930.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008544717.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_053597517.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053595450.1 14 MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589 "Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)" XP_014296796.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_014295901.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes" XP_053594777.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_053596718.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008550848.1 13 Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-450321 "FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_008554834.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_053597706.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_053598183.1 7 Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"UTP and CTP de novo biosynthesis" XP_008547602.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_008555753.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014298883.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_008559292.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008549676.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014296789.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147 "Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I" XP_053596121.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014297439.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_053594023.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_008558802.1 8 KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_053597171.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_008545962.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008559861.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" XP_014296371.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014298866.1 8 MetaCyc: PWY-5394;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581 "Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I" XP_008559230.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69183 "Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Processive synthesis on the lagging strand" XP_008547111.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_053597060.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008547002.1 10 KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation" XP_014299336.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_008559215.2 5 Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-9013973 "Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7" XP_008545606.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008549076.1 1 MetaCyc: PWY-6938 "NADH repair" XP_014298300.1 14 Reactome: R-HSA-434316;Reactome: R-HSA-418217;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G beta:gamma signalling through PLC beta";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_014300588.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_053595900.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_008549132.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053599022.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008545784.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558 "PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_008545268.1 26 Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781 "TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression" XP_053596006.1 7 MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1 "L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism" XP_008550652.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008553789.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008558331.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_008548423.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105 "Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation" XP_008548581.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_008543345.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008553211.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" XP_053596962.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_008549448.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_008547255.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_008553885.1 7 MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824 "Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis" XP_008554719.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008559998.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008545121.1 7 MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-7282;MetaCyc: PWY-6277 "5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_008551236.1 18 KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642 "Novobiocin biosynthesis";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation" XP_053598911.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_008548495.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008546493.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_008546631.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_008558945.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008548525.1 19 MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383 "Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_053594531.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_008558068.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008547573.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_053596941.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_053597739.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008544745.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-8086 "Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_053593641.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_053596489.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol" XP_008559557.1 30 Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-199418;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-211163;Reactome: R-HSA-111447;Reactome: R-HSA-198323;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69656;Reactome: R-HSA-8948751;Reactome: R-HSA-389513;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-6804758 "RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Regulation of TP53 Degradation";"AKT-mediated inactivation of FOXO1A";"Activation of BAD and translocation to mitochondria";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of PTEN stability and activity";"CTLA4 inhibitory signaling";"Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Acetylation" XP_008543453.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008554533.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_008558074.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008548167.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_008554435.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_053594862.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_053595374.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014297406.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_053595214.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6837 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_053593213.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_008550790.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_014297135.1 5 MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_008549617.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008543313.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_008544849.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014297734.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053594266.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014300817.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_053593823.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_008543907.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_053593767.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_008558674.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_014300570.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_008555491.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_008556934.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014296460.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008559842.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008550298.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_053593041.1 7 MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Purine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Adenine salvage";"Purine metabolism" XP_053596039.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008549017.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008555466.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_014299237.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008547324.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008546214.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_008556794.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008546824.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008550757.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008554085.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053595235.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014295402.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_008543468.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008546546.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008550192.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_053594155.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_008553095.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053595445.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_014300869.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_008549746.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008557035.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014296695.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_014295716.2 5 Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_014300850.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_008555562.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_014298329.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008544944.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008558400.1 11 MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-5675 "Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)" XP_014299475.2 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_014295267.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008559436.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-1839117;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"Human cytomegalovirus infection";"mTOR signaling pathway";"NRAGE signals death through JNK";"Rho GTPase cycle";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection" XP_053593225.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053594821.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008548835.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008561214.2 13 Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883 "Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II" XP_008548999.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008547589.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_053593815.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014296023.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008550504.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547333.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008546445.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008556134.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053593293.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_008550912.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_008552884.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_008543381.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_008557014.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_008555624.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_053597408.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008558571.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_008543629.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_008556549.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053594643.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_008546929.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008551220.1 7 KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;Reactome: R-HSA-9033241 "Geraniol degradation";"Butanoate metabolism";"Synthesis of Ketone Bodies";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Peroxisomal protein import" XP_053596921.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_008551446.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_008554939.1 11 Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796 "mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_008548355.1 14 MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5076;MetaCyc: PWY-5057;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42 "L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-leucine degradation III";"L-valine degradation II";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"Branched-chain amino acid catabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis" XP_053598731.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008544933.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_053596575.1 9 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"mTOR signalling";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" XP_014298642.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008556655.1 13 MetaCyc: PWY-8052;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2424491 "2-arachidonoylglycerol biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling" XP_008557860.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008551078.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008556908.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_053598983.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_053597593.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5857;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855 "Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_053596985.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_008544793.1 52 Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648 "NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_008557231.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_008559409.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA" XP_008553507.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_053594279.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008552635.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053594634.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_008552014.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053593354.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_008555541.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008556384.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008559822.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_008559226.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_008556143.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" XP_008549792.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_053592919.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_008558145.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_014298811.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_008548171.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_008548434.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008545985.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_008548684.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_053598868.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008552591.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_008557189.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" XP_008549730.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586 "HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence" XP_014298168.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_008550364.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_008556055.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_008551678.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053593414.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008547191.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_008544937.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008544258.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467 "Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Kinesins";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs" XP_053598577.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008559959.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-201722 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex" XP_008555926.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008545546.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053 "Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II" XP_008545290.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_053598728.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008549221.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" NP_001401788.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008553136.1 7 KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid" XP_008547857.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_008559674.3 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_008544046.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_008550624.1 5 MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" XP_053599054.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014297616.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014296722.1 24 Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434 "Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Cilium Assembly";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008552088.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_008554004.1 4 KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" XP_008556278.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014296716.1 6 MetaCyc: PWY-622;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_008555504.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_008545836.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_053593847.1 12 KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-7118 "Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol" XP_053597698.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852 "Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy" XP_008558701.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "Myogenesis";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_008545833.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008543892.1 5 MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;Reactome: R-HSA-6798695 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation" XP_008560859.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008559984.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_008560150.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053595357.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008547542.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008550807.1 10 MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-1722 "Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_008553722.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008551002.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_008543830.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_053598446.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008547832.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_008560154.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_053593361.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_008554604.1 14 MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-3841 "Folate transformations I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)" XP_053595417.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008558057.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_008544952.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014296777.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008559568.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_008554316.1 10 KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153 "Human cytomegalovirus infection";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway" XP_008550260.1 8 MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27 "Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_053593269.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008552818.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014296528.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)" XP_008548158.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008553109.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_008548986.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_008553363.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008554872.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_008546256.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_053594047.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_008544630.1 7 KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" XP_053597856.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053596530.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_008549081.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_008551707.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768 "Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_014298697.1 11 Reactome: R-HSA-191273;MetaCyc: PWY-7560;MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-6383;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-6174;MetaCyc: PWY-7524 "Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)" XP_008555146.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_008554456.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_053594761.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008546048.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497 "AURKA Activation by TPX2";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008545809.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_008548576.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_008551651.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_053596356.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008546837.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014297282.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_008551179.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_053598703.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-69166;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014296804.1 8 KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_008558997.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-389977 "COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway" XP_008547337.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053595476.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008544464.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_053594838.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014295717.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695 "STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation" XP_008546182.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_053593297.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_053597163.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_014300679.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation" XP_053594548.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008543065.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008546648.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008557977.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053595852.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014298650.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_008553777.1 19 Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-418885;Reactome: R-HSA-3928662 "G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"EGFR downregulation";"DCC mediated attractive signaling";"EPHB-mediated forward signaling" XP_008556927.1 3 KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" XP_008551324.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008553140.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014298097.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008549937.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008549258.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_053598235.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_053594871.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014297095.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008558491.1 7 MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_053596408.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008543729.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891 "Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)" XP_008553723.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_008557549.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008551003.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_008551982.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_008544285.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_008552143.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_008550563.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_008553502.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014298124.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_008551288.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_014299631.2 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_008547546.2 5 MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201 "Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I" XP_008555239.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862 "Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_008550878.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014295584.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_008549750.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_008547294.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014300536.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014296795.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_008553073.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_008560831.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_053595911.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053595853.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_008554568.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_053594135.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_053593071.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_008550917.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_053597162.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_053593160.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_014300540.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008555945.1 11 MetaCyc: PWY-7456;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-5659 "Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis" XP_014300296.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008550303.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5857 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_008550169.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_008544081.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801 "POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair" XP_053598368.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_008557055.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008551778.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER" XP_008546191.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053593159.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_053599047.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_008550864.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_014297283.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_008555331.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_053594994.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_008548268.1 4 MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_053598702.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-174437 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand" XP_008556859.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_008548760.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008555802.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008544174.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008546853.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008548855.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_008546911.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_008557359.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_008560147.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053597575.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_008560770.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008551270.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053596971.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_053594229.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_008557360.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_014298944.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547413.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014299820.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_008556154.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_008551450.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008544693.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-6608;MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5532;Reactome: R-HSA-74217 "Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage" XP_008551028.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053597473.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008548759.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_008556860.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_008544431.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_008554323.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_053594819.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008558753.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation" XP_014299210.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13 "Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system" XP_014300509.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_053595344.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_053598450.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_008556720.1 14 MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6538;Reactome: R-HSA-8851680;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6607;MetaCyc: PWY-6999;KEGG: 00232+1.17.3.2;MetaCyc: PWY-5695 "Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine nucleotides degradation I";"Theophylline degradation";"Caffeine metabolism";"Inosine 5'-phosphate degradation" XP_008556922.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_008555010.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_008557972.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880 "Relaxin signaling pathway";"HATs acetylate histones";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Ub-specific processing proteases" XP_008550074.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008544746.1 13 MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086 "TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_008544669.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_008550307.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_053593292.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_008554510.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014295910.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_008545698.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_008557582.1 7 Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism" XP_008553664.3 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_053593861.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014299759.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_053594265.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014300474.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_014296022.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_053596550.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014294888.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_053598270.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008558001.1 18 MetaCyc: PWY-5913;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-6728;MetaCyc: PWY-561 "Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_008554436.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_053598469.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008560360.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_053596098.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_014297136.1 5 Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_008546832.1 17 Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942 "Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)" XP_008550239.1 12 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-447038 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Trafficking of AMPA receptors";"NrCAM interactions" XP_008554105.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_008551481.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_008550724.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_053598778.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014294986.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008555976.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014295448.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008551702.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_008545569.1 4 KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008556070.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_008548718.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_053599211.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_008555610.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_053594042.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008557020.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_008554086.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008545550.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_008554877.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_053596698.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_053597798.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008544598.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008544428.1 6 MetaCyc: PWY-6907;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-7356;Reactome: R-HSA-196819 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism" XP_008557278.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296772.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_053597477.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008554327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008556587.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008561060.1 26 Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-389960 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC" XP_008549675.1 39 Reactome: R-HSA-109704;Reactome: R-HSA-5654228;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654221;Reactome: R-HSA-2033514;Reactome: R-HSA-190371;Reactome: R-HSA-5654704;Reactome: R-HSA-5654699;Reactome: R-HSA-5654219;Reactome: R-HSA-190372;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-5654688;Reactome: R-HSA-2033519;Reactome: R-HSA-5655253;Reactome: R-HSA-5654689;Reactome: R-HSA-8853338;Reactome: R-HSA-190322;Reactome: R-HSA-5654719;Reactome: R-HSA-5654726;Reactome: R-HSA-5658623;Reactome: R-HSA-1257604;Reactome: R-HSA-1839130;Reactome: R-HSA-5654227;Reactome: R-HSA-5654732;Reactome: R-HSA-1839122;Reactome: R-HSA-5654727;Reactome: R-HSA-2219530;Reactome: R-HSA-5654720;Reactome: R-HSA-190375;Reactome: R-HSA-5654706;Reactome: R-HSA-5654710;Reactome: R-HSA-5654687;Reactome: R-HSA-5654733;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-190373;Reactome: R-HSA-6811558 "PI3K Cascade";"Phospholipase C-mediated cascade, FGFR4";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"Phospholipase C-mediated cascade, FGFR2";"FGFR3 mutant receptor activation";"FGFR3b ligand binding and activation";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"FGFR3c ligand binding and activation";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"SHC-mediated cascade:FGFR1";"Activated point mutants of FGFR2";"Signaling by FGFR2 in disease";"PI-3K cascade:FGFR1";"Signaling by FGFR3 point mutants in cancer";"FGFR4 ligand binding and activation";"SHC-mediated cascade:FGFR4";"Negative regulation of FGFR1 signaling";"FGFRL1 modulation of FGFR1 signaling";"PIP3 activates AKT signaling";"Signaling by activated point mutants of FGFR3";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR3 signaling";"Signaling by activated point mutants of FGFR1";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR4";"FGFR2c ligand binding and activation";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR3";"Downstream signaling of activated FGFR1";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"FGFR1c ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_008549725.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_008556688.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008559895.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008556438.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_053599034.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events" XP_008555197.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_008556142.1 5 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs" XP_008549793.1 7 Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_053598764.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_053594747.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_008547547.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_008560714.1 5 KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536 "Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis" XP_008554918.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_053594170.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_053596309.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008559823.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_008544110.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597840.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_008560839.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_008549402.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053593058.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014296578.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_008556206.2 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_008554440.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_008545605.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_053598982.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_053595209.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008547048.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_008543765.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_014298797.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008553886.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis" XP_008547256.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" XP_008544932.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008545813.1 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_008559852.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_008559965.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008551297.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_053593874.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008552311.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_053593051.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008546099.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_053595395.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014298839.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008557402.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_008553113.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008543119.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008553400.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_053594567.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_008560258.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_053595067.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008550170.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008561178.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008553993.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_008556431.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_008544860.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008560750.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053596813.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_008547373.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_053593651.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_053595099.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_014299103.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_008556879.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014299242.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_053597273.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014299369.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_053593707.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008557829.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008558399.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014300388.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_008548779.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008559182.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008556775.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation" XP_008548381.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA" XP_008553925.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053595667.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_053598719.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_008549788.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_053596295.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008555406.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_008559837.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008560769.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008560646.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_008556285.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_053599218.1 15 Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034 "RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins" XP_008548711.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008553519.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008555333.3 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_053599192.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_008544485.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053593731.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_053598771.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_053593966.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053596535.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_014296744.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_053598843.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_053596845.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014295348.2 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_014298806.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300 "Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_014297644.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" NP_001401775.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_053593983.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014296145.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053598685.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_053599130.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008559357.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_053597783.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900 "Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4" XP_008556953.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_053598106.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008549582.1 8 MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-7391 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_014300138.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_053595762.1 18 Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922 "Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI" XP_008550858.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008552675.1 14 KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I" XP_008557944.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008547411.3 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008547062.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008553744.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_008546574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008559390.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008549972.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_053598414.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_053596091.1 14 KEGG: 00232+1.17.3.2;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4+1.17.3.2;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6606;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6608 "Caffeine metabolism";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Drug metabolism - other enzymes";"Theophylline degradation";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III" XP_008549147.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport" XP_053596083.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-525793 "Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Myogenesis" XP_014294998.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008551488.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008546307.3 5 Reactome: R-HSA-8963896;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "HDL assembly";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_008560901.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_008554554.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008543684.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_008552781.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761 "Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling" XP_053594917.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014297001.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053598638.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008545452.1 7 MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1 "L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylketonuria";"Phenylalanine metabolism" XP_008544977.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_008558072.1 5 Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_008557030.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_008552865.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_053594864.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_053595226.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291 "Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_014294850.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_008558503.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692 "PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity" XP_008559353.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_014296482.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_053597787.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014298147.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014297732.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_053596687.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300 "HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors" XP_008557630.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_008558920.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_008556730.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_008553482.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_008559844.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008555170.1 6 Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52 "Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism" XP_008545873.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008552258.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_008555747.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_053593078.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008551685.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_053593810.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008559149.1 12 Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_053594197.1 3 MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism" XP_008555338.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053597826.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014297298.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_008552478.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_008547316.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008543320.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_053596876.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008549143.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008550229.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_053598361.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism" XP_008544088.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008549384.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_008551771.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008559534.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" XP_008560271.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008552797.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_053597376.1 6 MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA" XP_008551389.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_008546816.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008546686.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008552092.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_008549115.1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins" XP_014300314.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008554832.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902 "Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity" XP_014300274.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_008560829.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008548103.1 16 Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-1257604;Reactome: R-HSA-1810476;Reactome: R-HSA-975138;Reactome: R-HSA-975110 "MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"PIP3 activates AKT signaling";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling" XP_008547786.1 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_014295740.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008553752.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008560379.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" NP_001401730.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008554187.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053593430.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008550439.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_008546704.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_014297637.1 6 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_053593680.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_014300039.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_008560124.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_008558804.1 8 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-241 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_008548665.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_008557646.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_008558386.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008558027.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008560725.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_053595063.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_014297848.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008545401.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014299779.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9022692 "Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity" XP_008544916.1 14 MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-7124 "Rubisco shunt";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)" XP_008560933.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_008548350.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_008557754.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008549735.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008555956.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_008555188.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_008549923.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952 "Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation" XP_053593080.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_053594878.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_053599024.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_014300335.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_008545782.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008557478.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008556428.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008549251.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_008544818.1 33 Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107 "Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_008543888.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_014296752.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_014296950.1 6 Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2 "Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism" XP_014300639.1 11 KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680 "Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity" XP_008545570.1 4 Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_008556069.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008547791.2 8 KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-7179 "Purine metabolism";"Surfactant metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I" XP_008549839.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs" XP_053596907.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053599169.1 4 Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50 "Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_053594831.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_053593751.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008560650.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_053598553.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053594260.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" XP_008557329.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_053596555.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008558795.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008549142.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_008551246.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_008560669.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_053595041.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_008548881.1 14 MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Respiratory electron transport" XP_008557174.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_008554515.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_053594259.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_008549438.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_053596453.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053598455.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008548729.1 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_008552233.3 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_008551842.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_008553483.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation" XP_014299164.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008548679.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_008555634.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_008553521.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008557081.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_008550838.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008547099.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_053595373.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_008545555.1 18 MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_053593214.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_053597444.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_008552811.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008552953.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053593129.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547568.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_014297449.1 11 MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis" XP_008544143.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008555034.1 19 Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-3000484 "Retinoid metabolism and transport";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Chylomicron clearance";"LDL clearance";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Cell surface interactions at the vascular wall";"VLDL clearance";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors" XP_008559596.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_008559426.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_053595641.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008554534.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008551557.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008544806.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_053598160.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008550358.1 8 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins" XP_008547574.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_008555885.1 31 MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-5994 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)" XP_053598854.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014296753.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_053597514.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053593702.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_008545783.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling" XP_008555371.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_008543784.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_053596600.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" XP_014296044.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_053598159.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_008561065.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053597091.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR" XP_053595245.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_008550418.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258 "PCP/CE pathway";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL" XP_008552879.1 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_008550742.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_008561036.3 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053598721.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" XP_008556451.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_053596649.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_008549228.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-390471 "BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis" NP_001401781.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_053595062.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008557168.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_053597749.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_008543855.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_053597208.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008549196.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_053594024.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_008552025.1 6 KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate" XP_008557407.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008554477.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008546808.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_053593425.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_008555754.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy" XP_008553753.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_053596791.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_053598785.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_008543759.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008554445.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching" XP_008559301.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008544839.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_008558362.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_053597845.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008554833.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008556311.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008550034.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014296601.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_008555120.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_014300060.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_053597452.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014296757.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008557730.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_053598118.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008547822.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008550319.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_014300059.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008554476.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014294948.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_053597272.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008550279.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014295486.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008547226.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_014300684.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008559166.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_053597876.1 5 KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_053597087.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053593527.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593497.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_014298724.2 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_008558016.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008554547.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_014296790.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_053595456.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008550015.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_008550634.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008553112.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008549154.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion" XP_008549231.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008555047.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676 "Role of phospholipids in phagocytosis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_008551159.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_008547409.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_053594364.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis" XP_008555796.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_008545376.1 5 Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-193048 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis" XP_008557957.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053597437.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014296930.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014295172.1 4 Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710 "Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy" XP_008545812.1 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization" XP_008559853.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_008545826.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_008561029.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008556901.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_008560642.2 9 MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_014296946.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008556478.1 9 MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis" XP_008552792.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_014294892.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_053592876.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014295305.1 24 Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G-protein activation";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_014300835.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" XP_053594828.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_053596082.1 11 Reactome: R-HSA-8940973;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "RUNX2 regulates osteoblast differentiation";"Myogenesis";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_008548180.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008547327.1 17 Reactome: R-HSA-8953750;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_008543388.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008555940.1 5 MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523 "Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)" XP_053593165.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695 "Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Regulation of insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_008549583.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008553487.1 56 Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553 "Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs" XP_008551334.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787 "Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'off' state" XP_053595763.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_053593288.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_014298142.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_008557650.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_008560681.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II" XP_008550789.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_053595827.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation" XP_053597980.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053599125.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008549614.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_053597782.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053595217.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6 "(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism" XP_014300224.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053598842.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_008557365.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_008548346.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" XP_008547105.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_008551455.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_053595377.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_053595004.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_008551315.1 5 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_008548164.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_053599181.1 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_014295009.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541 "RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation" XP_014300119.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_008544972.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_008544770.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418597 "Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events" XP_008558077.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008558304.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_053592978.1 9 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008550643.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008552110.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246 "Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript" XP_014299881.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_008556646.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_008556769.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_014298056.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_008560560.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_053597850.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008557017.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_008545397.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_008551323.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008555627.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053593965.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008554028.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008543530.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_008556286.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_008551873.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism" XP_008547532.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_014297150.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_053596350.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_053598686.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_008554270.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" NP_001401776.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008550507.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008554310.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "mTORC1-mediated signalling";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_053598105.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008558188.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_014296908.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008543840.1 12 KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+2.1.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.2;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196780;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613 "Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_053596846.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008550862.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008546269.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014296360.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008550955.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_014296803.1 8 KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_053598704.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_053597869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008555386.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_008559651.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_008545350.1 10 MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation" XP_008551099.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_053593648.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_053594112.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_008554778.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053598063.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_008554335.2 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_008555027.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_008546732.3 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_053593182.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014296380.1 9 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008555363.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014300301.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_053595342.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014297880.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_053593837.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_008554603.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_053596509.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_008557448.1 6 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)" NP_001401717.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008550367.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008547998.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008548588.1 7 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_014296710.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_053594848.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008553828.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008548687.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_008543938.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_014295278.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167200 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_008544305.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008556387.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053595396.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008550023.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_053592850.1 7 Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-2151201 "Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_008545128.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408 "Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation" XP_053593357.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_008547861.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014298122.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053598226.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_053598440.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_014296130.1 10 Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-983231 "Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production" XP_014299683.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_053598372.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_008545509.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_008548876.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014297339.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008547230.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_008554003.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008550841.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_008544756.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053596296.1 5 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation" XP_008555136.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids" XP_053594037.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053595638.1 3 Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_008544640.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" XP_008550623.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053595488.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-3134973 "Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production" XP_053597392.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_008547118.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053599053.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008555405.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_014295582.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_053594946.1 6 KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22 "Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions" XP_008552518.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_008556776.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008543546.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_053596892.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_014296378.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_014294903.1 6 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_008557712.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_014296549.2 7 MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_053597178.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection" XP_014298733.2 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation" XP_008550363.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_008558054.1 52 Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-73780;Reactome: R-HSA-427413 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression" XP_053599176.1 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III" XP_008555008.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_008554607.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_053593413.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008558871.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_008548691.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008558689.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_008554508.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008561148.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053599032.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_008545474.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_008560676.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_008551440.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_008556144.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_053597611.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5576892 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Phase 0 - rapid depolarisation" XP_014295908.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_053598762.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_008557891.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_008552013.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053594521.1 6 MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism" XP_008546389.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_008543921.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_053594975.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_008557645.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_008548535.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008551813.2 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_008546085.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014300336.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" XP_014298579.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008555507.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_008560190.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014297587.2 3 Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_008555955.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_053595685.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008559078.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_053597594.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053594033.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008550627.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_008550777.1 6 Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_053592881.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014298441.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation" XP_008559446.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053595621.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_008550498.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008545381.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008557013.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_008545629.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008550287.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_008558734.1 6 Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis" XP_008550136.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-69205 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription" XP_014300191.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_053596029.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008558406.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_008554031.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_053595293.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-936440 "TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling" XP_053593294.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_008552883.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053597079.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008551086.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014297307.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_014296278.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008558994.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_014299227.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014298511.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-5668599;Reactome: R-HSA-4420097;Reactome: R-HSA-3299685;Reactome: R-HSA-1236973 "ROS and RNS production in phagocytes";"RHO GTPases Activate NADPH Oxidases";"VEGFA-VEGFR2 Pathway";"Detoxification of Reactive Oxygen Species";"Cross-presentation of particulate exogenous antigens (phagosomes)" XP_008550503.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-75815 "Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D" XP_053595225.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-6837 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_008559516.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_008552866.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_008559492.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_008546834.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_008554481.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_008550672.1 7 Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6724 "Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation II" XP_008544943.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008549248.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_053596629.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_008551686.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_008553807.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_053598395.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_008549709.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008545029.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_053595139.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_053594044.1 13 KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66 "Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Purine catabolism";"Purine metabolism" XP_008555367.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_014300237.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008549805.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_014300186.1 5 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-8963896 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"HDL assembly" XP_008546815.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008545107.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638 "RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_053597375.1 6 MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA" XP_053596875.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014296774.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs" XP_008547315.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796 "FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation" XP_008555077.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014295587.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547297.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008553917.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_053594032.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053592892.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008548457.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053595246.1 9 MetaCyc: PWY-5981;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_053595420.1 57 Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_008553864.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_053594558.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008548277.1 4 MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97 "Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism" XP_008551767.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_053598377.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_014297380.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_053595058.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" XP_008552012.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053593352.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008555578.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008559007.1 24 Reactome: R-HSA-444257;Reactome: R-HSA-5625740;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757 "RSK activation";"RHO GTPases activate PKNs";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation" XP_053598763.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_008544961.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_008544736.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008560713.1 5 MetaCyc: PWY-7536;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" XP_008560299.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_053597846.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008547269.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_008547342.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_053595905.1 10 Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-6798695;MetaCyc: PWY-5691 "Amyloid fiber formation";"Purine metabolism";"Retinoid metabolism and transport";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Neutrophil degranulation";"Urate conversion to allantoin I" XP_008551895.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053594690.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008548682.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_008547470.1 6 MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17 "L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism" XP_008543340.1 57 Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346 "CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Neddylation";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis" XP_053599033.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_008550551.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053596869.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" NP_001401712.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053593240.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_053593426.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_008550249.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_053597410.1 3 Reactome: R-HSA-5083635;Reactome: R-HSA-189085;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins" XP_008544996.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053598786.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_053595347.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_053593832.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_053598872.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053596556.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008550887.2 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_014299783.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_053593187.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_053597261.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_014298947.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008559031.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_008556726.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_053594117.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008550899.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_008555022.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-165054 "SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA" XP_008559900.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_008555016.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053597892.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_008556910.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008550673.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053592948.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_008549108.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008551245.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_053595738.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_008560539.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008554516.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014299649.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_014299766.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_008556190.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008559523.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_008544056.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_008555580.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014298636.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008556448.1 9 MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)" XP_014299600.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008547847.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008558120.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_014295196.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008559595.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_008544805.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_008560800.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014294980.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_008552882.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014295228.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Peroxisomal protein import" XP_008557012.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_008545392.1 7 KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268 "Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism" XP_008555622.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_053593857.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_008557026.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_008555551.1 10 MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" XP_008544694.1 17 KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5532;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-7179 "Purine metabolism";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I" XP_053597474.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014295884.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008554324.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550988.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination" XP_008558754.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_053595343.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_053593191.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_014298943.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547085.1 9 Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5 "Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism" XP_008545243.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR" XP_053592875.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008554874.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008555249.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_053595671.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008556300.1 9 Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-196780;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6142 "Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_053594113.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_008553206.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_053599001.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008548049.1 8 Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148 "Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008556968.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296599.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_053593166.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676 "Role of phospholipids in phagocytosis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_014296331.1 13 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation" XP_008546854.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_008556045.1 6 Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_008550863.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008559527.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_008553331.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)" XP_008546785.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_008553429.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008553599.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_053599112.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_008557849.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008552506.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_053599126.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053595160.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008550886.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550077.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008547533.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008550304.1 12 MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" XP_008544090.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008551316.1 5 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008560626.1 14 MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619 "Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis" XP_053598662.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008544511.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008551322.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053598808.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008551276.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_014295583.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_008554255.1 33 MetaCyc: PWY-6333;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-6802;MetaCyc: PWY-3162;MetaCyc: PWY-7798;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5078;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-7013;MetaCyc: PWY-1801;KEGG: 00625+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6587;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00626+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00010+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5079;MetaCyc: PWY-5480;MetaCyc: PWY-7111;MetaCyc: PWY-5082 "Acetaldehyde biosynthesis I";"Retinol metabolism";"3-methylbutanol biosynthesis (engineered)";"Salidroside biosynthesis";"L-tryptophan degradation V (side chain pathway)";"Protein S-nitrosylation and denitrosylation";"alpha-Linolenic acid metabolism";"Noradrenaline and adrenaline degradation";"Metabolism of xenobiotics by cytochrome P450";"Phenylethanol biosynthesis";"Fatty acid degradation";"Pyruvate fermentation to ethanol II";"L-isoleucine degradation II";"L-valine degradation II";"L-leucine degradation III";"(S)-propane-1,2-diol degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Chloroalkane and chloroalkene degradation";"Methane metabolism";"Pyruvate fermentation to ethanol III";"Chitin degradation to ethanol";"Ethanol oxidation";"Naphthalene degradation";"Drug metabolism - cytochrome P450";"Butanol and isobutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Tyrosine metabolism";"Glycine, serine and threonine metabolism";"Serotonin degradation";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"L-methionine degradation III" XP_008547281.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008549609.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_053596893.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_008552800.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053597779.1 5 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation" XP_053598939.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430 "Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_008559672.3 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_008554731.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_008550622.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053597381.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_053599052.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008558319.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_008545151.1 34 Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-167246 "RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Tat-mediated elongation of the HIV-1 transcript" XP_014298992.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014295485.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008554475.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_053593589.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_053598373.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053599205.1 15 Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_053597029.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_008547544.1 3 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_008558015.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008555935.1 5 MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863 "Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis" XP_008551377.1 13 MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" XP_008553724.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_008549127.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053599037.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_008553193.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_008555194.1 9 Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395 "Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER" XP_008545825.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_014296307.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_008545375.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis" XP_008554602.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008554868.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008559606.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014295035.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008555341.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014298915.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_008546334.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_008551694.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_053595280.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_053598805.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_008558002.2 7 MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7839;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836 "Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis" XP_008547203.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_053597303.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008543498.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_053593717.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014298686.1 4 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_014299113.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014294930.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008548997.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" NP_001401801.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014298510.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-1222556;Reactome: R-HSA-5668599;Reactome: R-HSA-1236973;Reactome: R-HSA-3299685 "VEGFA-VEGFR2 Pathway";"ROS and RNS production in phagocytes";"RHO GTPases Activate NADPH Oxidases";"Cross-presentation of particulate exogenous antigens (phagosomes)";"Detoxification of Reactive Oxygen Species" XP_008547438.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008548348.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_053598709.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_008548969.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053595927.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_008543804.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008545803.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_008550253.1 8 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism" XP_008548117.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053593137.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008545146.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014298327.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008557352.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_008556256.1 13 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_053598942.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_008554480.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_008560979.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_053598177.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008557426.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_053592878.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008553410.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008543363.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014300867.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_008553369.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014297897.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_053594216.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008557412.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008553846.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014295250.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism" XP_008550985.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008551511.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_053594826.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008554692.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_053595788.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_008559025.1 18 MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism" XP_053595264.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_008555705.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_008548057.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_008554952.1 28 Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-69473 "HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint" XP_014295038.1 4 KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;MetaCyc: PWY-6129;Reactome: R-HSA-446199 "Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate" XP_053596504.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_008556332.1 15 Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944 "Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2" XP_014299653.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008555798.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_008557236.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014300204.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_008553830.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_008547916.1 16 MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-2221 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_008546147.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_008546620.1 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_053595458.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" XP_008556390.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation" XP_008546972.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_008558018.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008548482.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008555938.1 5 Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_053598404.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053596912.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_053598736.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053597610.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775 "RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis" XP_053596926.1 16 MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5 "TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism" XP_014296509.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053596378.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_008559285.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008554478.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008543503.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_014296128.1 10 Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692 "Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity" XP_008544217.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_008547228.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-139915 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria" XP_008555232.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008550394.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_008548176.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008554046.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_008543287.1 13 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation" XP_008557857.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_053595972.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008558517.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_053595620.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008559221.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_053595147.1 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_014296261.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5632684 "Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state" XP_008543072.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_014298226.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008556801.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014298440.1 10 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange" XP_053592880.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008545710.1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459 "Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_053598122.1 5 KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_014294975.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_053595419.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442 "Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs" XP_008547189.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion" XP_008545260.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008552589.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_014300580.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_008557344.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097 "mTOR signaling pathway";"p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway" XP_008549212.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)" XP_008556149.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_053592913.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_053592851.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_053599087.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008559792.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008548145.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008549226.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_008556534.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_008545541.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_008555921.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_053597206.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008543266.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_014295533.1 10 Reactome: R-HSA-983231;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159 "Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system" XP_008547231.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_008544373.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_053593366.1 7 Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746 "NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein" XP_053596260.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_053597599.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008550356.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-141444 "S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014298984.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008560199.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008559957.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008558355.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_008554933.1 57 Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590 "Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Neddylation";"NIK-->noncanonical NF-kB signaling" XP_053598579.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053596351.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008560352.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_014297151.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_008547973.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014300578.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_008547485.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008558739.1 6 MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663 "Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_008546923.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053596807.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_008547566.1 3 Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008555141.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_053598511.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053596024.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_053597851.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053592802.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_008550546.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_008559598.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_053593713.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014299969.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008543695.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783 "Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome" XP_014296361.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008552183.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008549063.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_008559365.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_008546115.1 9 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008554944.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053595735.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_008560748.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008560209.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_008559650.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_008545562.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_053598173.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008548996.2 4 Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033 "Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones" XP_008556294.1 5 KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_053594049.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_014296325.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins" XP_053595471.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids" XP_053598694.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_053593267.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296393.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014298395.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_053595839.1 17 Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-1433557;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Activation of ATR in response to replication stress";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Transcriptional Regulation by E2F6";"Signaling by SCF-KIT";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_014296381.1 9 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_014295544.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597 "Purine metabolism";"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events" XP_014296779.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008560337.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008555309.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008548037.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_008557256.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014299975.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014298004.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_008545303.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008543282.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053593204.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008545231.2 15 Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_053596880.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014300023.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014295420.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_014295590.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296721.2 24 Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190861 "Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Gap junction assembly" XP_008548946.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008544372.1 33 Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_053595688.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_053594876.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008559075.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008544212.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_014299585.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation" XP_008553869.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-1834949 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA" XP_008556426.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053598009.1 10 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2 "Human cytomegalovirus infection";"mTOR signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"T cell receptor signaling pathway" XP_014295532.1 10 Reactome: R-HSA-1855204;MetaCyc: PWY-6365;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;Reactome: R-HSA-983231;MetaCyc: PWY-6554;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6366 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis" XP_008548538.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_014300531.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008556748.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_053593617.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_053597146.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008549213.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008555252.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014295658.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-186763 "VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"Downstream signal transduction" XP_053592912.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_008549799.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_008555472.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014297665.1 7 Reactome: R-HSA-1660516;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system" XP_008547264.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_053594588.1 12 Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1 "G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Thermogenesis";"Human cytomegalovirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway" XP_008555340.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008549939.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008555005.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_008550244.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "NrCAM interactions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_053597364.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_008556337.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN" XP_008554238.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_008548848.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_053593190.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008545586.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_053594817.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008554428.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint" XP_008546818.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008557417.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_014296178.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_053596328.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008555550.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_008544086.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_053597218.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008545563.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-165054 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA" XP_053593132.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053594964.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053599000.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053593076.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_053598398.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008559271.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053595670.1 30 Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5684264;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-2122947 "Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Circadian Clock";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription" XP_008556301.1 9 KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599 "Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency" XP_008544066.2 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014298555.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053595228.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_008558370.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-9610379 "SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events" XP_008547582.1 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;MetaCyc: PWY-7886 "Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" XP_008548790.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_053599049.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053593157.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_008553330.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_008543580.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis" XP_008556890.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008555201.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_008560515.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_008550167.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_053592803.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_053596610.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription" XP_008553178.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_053593712.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008545010.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008557390.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178 "Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_008547972.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053595161.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008546922.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008547908.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase" XP_053597479.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_008548753.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167290 "RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation" XP_014297254.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053596429.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_008558006.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008554431.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_014295671.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_008547419.1 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6842 "Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II" XP_053593866.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_014295721.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008543362.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008543249.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014298494.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008557413.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_053598499.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008560390.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_008550856.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008559092.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_014295184.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_053598943.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_008551463.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014300136.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_053593645.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_008557515.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_008559901.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_008550252.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_008546859.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_008545429.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_014298808.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_053595755.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_008555581.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_053595231.1 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" XP_008556191.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014299757.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244 "HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation" XP_008551398.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008557534.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008548644.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580 "Cleavage of the damaged purine";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"DNA methylation";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Meiotic recombination";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence" XP_053599216.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695 "Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events" XP_008550309.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_053592807.1 6 MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_008543200.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_053596802.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-5620922 "PKMTs methylate histone lysines";"BBSome-mediated cargo-targeting to cilium" XP_008560801.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053597768.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_008543073.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_053594066.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism" XP_053594514.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_008559952.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014298799.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_014296215.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"HATs acetylate histones" XP_008551609.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014300386.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008546035.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_053595014.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053595635.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008555408.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053595485.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-2644606 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_053598934.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_008549786.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014299538.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_053595973.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_053593974.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_014296825.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_053596674.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014298641.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_053592831.1 42 Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-110329 "RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Meiotic synapsis";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Meiotic recombination";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine" XP_014297381.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_008555233.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008553234.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_008561176.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_008550427.1 7 Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598 "PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Degradation of DVL";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_014297629.1 6 Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_008543502.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_008559646.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_008559478.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053596913.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_008560965.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008547251.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_053596074.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_008559797.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014300528.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_008543673.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_008549004.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008556979.1 10 Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands" XP_008548483.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_008548633.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_053594845.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008550550.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008558335.1 40 Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72165 "Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway" XP_008559258.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_008554953.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014299652.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_008548585.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_008546583.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670 "G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway" XP_008553375.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_053596993.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation" XP_053598995.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008560982.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" NP_001401731.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_053596449.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550320.1 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_008550870.1 3 MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51 "Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation" XP_008544184.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014299202.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008559608.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008546462.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014298261.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_008560003.1 7 KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4 "Glycerophospholipid metabolism";"Synthesis of PA";"Choline biosynthesis III";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Ether lipid metabolism" XP_053598839.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_008554866.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_008546094.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008548351.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_008554891.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_008548562.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499 "Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane" XP_008549250.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053598500.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008552425.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008556324.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_008545993.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_008553444.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008559286.1 24 Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-456926 "G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G-protein activation";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)" XP_008547195.1 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-1187;Reactome: R-HSA-71240 "Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Tryptophan catabolism" XP_014299364.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008555835.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008548774.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_053594011.1 5 KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22 "Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_014295099.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_014297907.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_053596400.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008544160.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_008545571.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008560165.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6722 "Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Candicidin biosynthesis" XP_008549470.1 5 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-8963896;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"HDL assembly";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_008546173.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_053593025.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008551264.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_008560497.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014296433.1 4 KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_008557031.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_008555513.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_008553514.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_008548768.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_008560778.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_008544019.1 7 Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204 "Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol" XP_008560628.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_008551318.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008559101.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_008554013.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_008551458.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008547108.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_008555084.1 5 Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976 "Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols" XP_014296749.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_014295574.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008557368.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_008557702.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053599128.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008543654.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_008559612.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053595441.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014296208.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008553902.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_008549468.2 5 Reactome: R-HSA-8963896;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "HDL assembly";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_008547467.1 6 MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17 "Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation" XP_008552129.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053597044.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_008544619.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053593285.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation" XP_008545145.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_008551582.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008555171.1 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_008547499.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053594729.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_053593168.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695 "Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Regulation of insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_008556731.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_014296663.2 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_008557949.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008557631.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053598359.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_008557481.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_008546579.1 15 Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-111465 "Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins" XP_008560310.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014298354.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008550986.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008545053.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008555706.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-450520 "Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA" XP_053593221.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_014299714.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_053598360.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_008552824.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" XP_053594825.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008556983.1 10 Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_008543321.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion" XP_008555434.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis" XP_008559387.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_008552007.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism" XP_014298369.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_053598655.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_053594215.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_014297049.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_008543689.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_053596653.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_053593953.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014299504.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_053593811.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008544532.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008549085.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" NP_001401680.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053598770.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014295198.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014297787.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008550739.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008546404.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_008560523.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_053594164.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053595122.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_014296588.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_008547565.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008556078.1 11 Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_053595898.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008551908.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014295226.1 42 Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-110331;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-3214842 "Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Cleavage of the damaged purine";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Meiotic recombination";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"HDMs demethylate histones" XP_014300043.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008556810.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_053599131.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014300754.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I" XP_053593792.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008557310.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_008543696.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008544842.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014300155.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_008553312.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008550967.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_008545482.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint" XP_008555018.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053597112.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257 "Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RAF activation";"Resolution of Sister Chromatid Cohesion" XP_008551055.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014296326.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_014297216.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" NP_001401703.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008559849.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_008547947.1 3 Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60 "Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation" XP_008546116.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_008554518.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008560031.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_008546122.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" XP_053596558.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_008552982.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_008552780.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585 "CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G" XP_008548378.1 8 MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387 "ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Photosynthesis";"Insulin receptor recycling" XP_053596701.1 1 Reactome: R-HSA-419771 "Opsins" XP_008544905.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_008558798.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008550814.1 52 Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-76071;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape" XP_008543338.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008548923.2 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014295918.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_008553588.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008550224.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_053593238.1 10 KEGG: 04151+2.7.1.153;KEGG: 04070+2.7.1.153;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153 "PI3K-Akt signaling pathway";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_053593957.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008559539.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_008548192.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_014295409.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053596090.1 14 KEGG: 00232+1.17.3.2;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4+1.17.3.2;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6607;MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6606;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6608 "Caffeine metabolism";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine nucleotides degradation I";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III" XP_008559391.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008544557.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008552003.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_008548364.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_053597052.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_008560824.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596997.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008544998.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008547609.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053598264.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" NP_001401728.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_008550684.1 11 Reactome: R-HSA-512988;Reactome: R-HSA-210990;Reactome: R-HSA-909733;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-389948;Reactome: R-HSA-432142 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"PECAM1 interactions";"Interferon alpha/beta signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"PD-1 signaling";"Platelet sensitization by LDL" XP_008555111.2 9 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_008545950.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_008559299.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_053594247.1 6 MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_008546056.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053593428.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008545117.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008550171.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008552028.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_053597487.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731 "FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3" XP_014296782.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008547040.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_008548803.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_053597205.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_008556084.2 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008545969.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_053595177.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_008547305.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008544738.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_008553401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008548146.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053594556.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008559924.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-350054 "RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway" XP_053593365.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008557003.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_008551735.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_053595248.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_053593650.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_053595056.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_008549139.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008544861.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_053596969.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_053594178.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_008550513.1 16 Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795 "SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling" XP_014299562.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_008551471.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008544292.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014297317.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008548380.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-6453 "Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis" XP_008557572.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008550355.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus" XP_014295686.1 3 Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870 "Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins" XP_008556064.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_014294878.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_008553570.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014296817.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_008546177.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_053599164.1 4 KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines" XP_008548193.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_008560080.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008544085.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_008556374.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008546794.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_008551142.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4 "Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism" XP_008556007.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008555335.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_008551688.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_053593075.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008547173.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_053595915.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_008549246.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_008546123.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_053598035.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_008545521.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008552573.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008551587.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008555941.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_053597113.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220 "Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins" XP_008546934.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_008548724.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008561192.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180910 "Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs" XP_008553907.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism" XP_008555274.1 8 MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis" XP_008544843.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008550820.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053593829.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-3821;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397 "Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_053598421.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008556751.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination" XP_053597993.1 15 Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-9018519 "RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression" XP_053596585.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_053597981.1 7 MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_053593219.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008544685.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_008557651.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_053593793.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008559518.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_008552602.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053593781.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_014297444.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008549658.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_008558919.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_014300858.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_008560516.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_053598207.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_014295823.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-6791461 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P" XP_008555454.1 7 MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25 "Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system" XP_053596975.1 4 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis" XP_008558408.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_053599180.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_053598014.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_053596633.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053594381.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_008556949.1 22 MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I" XP_008559190.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_008557966.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008558525.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008547579.1 7 KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;MetaCyc: PWY-3385 "Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I" XP_053596044.1 30 KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1257604;Reactome: R-HSA-8876198;Reactome: R-HSA-1358803;Reactome: R-HSA-6804758;Reactome: R-HSA-6804759;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-389513;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-69656;KEGG: 04151+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-69202;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;Reactome: R-HSA-198693;KEGG: 04150+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-211163;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"PIP3 activates AKT signaling";"RAB GEFs exchange GTP for GDP on RABs";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Acetylation";"Regulation of TP53 Activity through Association with Co-factors";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"CTLA4 inhibitory signaling";"Human cytomegalovirus infection";"Regulation of PTEN stability and activity";"Cyclin A:Cdk2-associated events at S phase entry";"PI3K-Akt signaling pathway";"Negative regulation of the PI3K/AKT network";"Cyclin E associated events during G1/S transition";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the nucleus";"mTOR signaling pathway";"Activation of BAD and translocation to mitochondria";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Thermogenesis" XP_008550512.1 16 Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1251985;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530 "GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Nuclear signaling by ERBB4";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_014300879.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008550496.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053598859.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008543211.1 13 KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259 "Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism" XP_053596753.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014298854.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_008553783.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_008559076.1 6 Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053598154.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_008559887.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_053594875.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014299586.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_008555185.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_053598231.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_053596644.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053595943.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_008549230.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014295906.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555 "PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events" XP_053597744.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_014296783.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_008554133.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_008545044.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014299328.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_008553600.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_008555759.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053599178.1 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_008545753.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053594107.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008544834.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014296931.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014297666.1 7 Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67 "Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_008549118.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_008560304.3 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008556527.1 10 MetaCyc: PWY-5691;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225 "Urate conversion to allantoin I";"Neutrophil degranulation";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Purine metabolism";"Amyloid fiber formation" XP_053595486.1 26 Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856 "TRAF6 mediated IRF7 activation";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling" XP_008547116.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion" XP_008547898.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014297876.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008543120.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008559349.1 33 Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-69231;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-8939236;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-167160 "Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_053597032.1 15 MetaCyc: PWY-2221;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6901 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Rubisco shunt";"Superpathway of glucose and xylose degradation" XP_008544297.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_053597176.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_053594065.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_008560111.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008556778.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008554862.2 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_008549184.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053598161.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014296216.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_008554717.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008557728.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "Rap1 signalling";"cGMP effects";"Ca2+ pathway" XP_053599102.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" XP_008548878.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008549721.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014298896.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_053593464.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_053597090.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2644606 "Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_008558427.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053592950.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008558698.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236 "HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_008559891.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008550489.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_008545112.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_053598720.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" XP_008547996.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008548586.1 7 KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism" XP_008545757.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_008560002.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008543796.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_008556469.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_008553376.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_008556270.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008559300.1 12 Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167290 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation" XP_008549071.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation" XP_008553826.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_053594846.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014295763.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008556982.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053593865.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_053596652.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_053593952.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053593750.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_053594830.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014299239.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008558005.1 10 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1 "Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway" XP_008556003.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008544361.1 56 Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236 "Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_008553520.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053596037.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008546640.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008557064.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014297817.1 14 Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_014296082.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_008548880.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_053594128.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism" XP_008552577.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_053595040.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_014296317.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_053597117.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_008544847.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008552810.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053593478.1 7 MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36 "3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_014300819.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_008553317.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_053598438.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014296148.1 3 Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151 "eNOS activation";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_008553903.1 4 KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism" XP_053594509.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_053593797.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_008548150.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008558911.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_008557080.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595756.1 17 Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942 "Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)" XP_053598587.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_008554026.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014295004.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression" XP_053595127.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008544488.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053599215.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167246 "Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript" XP_008557664.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_053596637.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053593258.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053598142.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008556288.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_008556764.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_008554387.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_008555512.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_053598977.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008553457.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014296394.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014295543.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008552159.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008555468.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_008560842.1 4 Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053598329.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_008548819.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053598431.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053598693.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008545367.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_053593251.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789 "Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_053598174.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008555029.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_008552071.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008556293.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053593134.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053594962.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008556719.1 14 MetaCyc: PWY-6538;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00232+1.17.3.2;MetaCyc: PWY-5695;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6607 "Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine catabolism";"Caffeine metabolism";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Guanosine nucleotides degradation I" XP_014298324.1 3 MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96 "L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis" XP_014297890.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_053598775.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport" XP_008554529.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_053596623.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053596531.1 13 MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_008544631.1 7 MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_008544481.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053596399.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling" XP_053593735.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_008543351.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" XP_008550296.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_053594185.1 13 Reactome: R-HSA-3928662;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;Reactome: R-HSA-416572 "EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse" XP_008559942.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008554108.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_008561219.2 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_008549064.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008558444.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008560905.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-3371571 "Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"HSF1-dependent transactivation" XP_008545695.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_008554467.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_053596023.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014298651.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_008543175.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_053593714.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014299042.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008557019.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_008551697.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_008552671.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_053593115.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_008546924.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053599158.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_008550065.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008552455.1 12 MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1 "Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Methane metabolism";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" XP_008549220.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053594039.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008543768.1 4 KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_008557854.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_008543284.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_008558066.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_053593202.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-6803207 "SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_014297581.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_053593143.1 16 Reactome: R-HSA-512988;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-1257604 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling" XP_008555289.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008549078.1 1 MetaCyc: PWY-6938 "NADH repair" XP_008559961.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_008552553.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014299096.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_008545608.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008558700.1 11 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-69231 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1" XP_014299338.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_053599018.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_008560347.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-110331 "Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Cleavage of the damaged purine" XP_014296575.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008556085.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_008558091.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014300465.1 6 Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-6731;MetaCyc: PWY-5941 "Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen degradation II" XP_008558083.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_014300586.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_008544824.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_014298966.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation" XP_008558666.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_053593359.1 52 Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-73780 "RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation" XP_053594941.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_008550536.1 7 MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-71064 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Lysine catabolism" XP_053598407.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008550665.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008543259.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_008544751.1 7 MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-46 "Urea cycle";"Arginine and proline metabolism";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III" XP_008544508.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_053593655.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273 "Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis" XP_008558683.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_008559898.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014300207.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_008550846.1 13 Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-450302 "TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation" XP_008557343.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008550242.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736 "Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Trafficking of AMPA receptors";"Purine metabolism";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors" XP_014299696.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_008548054.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008544235.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_014296162.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_014296929.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008556396.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" XP_008553546.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly" XP_008546612.1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581 "rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation" XP_008547726.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_053594526.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_014300668.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582 "Meiotic recombination";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Meiotic synapsis";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)" XP_053595012.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014295141.2 15 Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290 "RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation" XP_008550381.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_053598730.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053597622.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_053596716.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597616.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion homeostasis";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors" XP_008560721.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053593972.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_008550629.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008551221.1 4 KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281 "Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_053596672.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_053599059.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation" XP_008553232.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008559752.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008549111.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008552557.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008544982.1 10 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection";"mTOR signaling pathway";"Recycling pathway of L1";"Thermogenesis" XP_008551285.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008561034.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008545503.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_008543504.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014297550.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008554040.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014298810.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_008555892.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_053595776.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_008550029.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_008546387.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_053595626.1 17 Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2 "Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis" XP_008559441.1 7 Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795 "HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_053593020.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_008546026.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053599084.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_053593458.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_008545920.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_008555540.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008547076.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_053596405.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008560160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008544006.2 14 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-110320 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH" XP_008556488.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053598403.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008558687.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_014299669.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008547190.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_008558437.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" XP_008552842.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_014299089.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008560159.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053598238.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_053598505.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008552246.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_008556847.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_008557729.2 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_053596503.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008547448.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_014299654.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_014300429.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_008548338.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008553798.1 17 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-1433557;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Signaling by SCF-KIT";"Human papillomavirus infection";"Transcriptional Regulation by E2F6";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Activation of ATR in response to replication stress" XP_008543378.1 14 KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Synthesis of PE" XP_008558227.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_008551025.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014296844.2 5 MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Neutrophil degranulation";"Folate biosynthesis" XP_014295547.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008545109.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_053598697.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008553104.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008555369.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-349425 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1" XP_008548285.2 12 MetaCyc: PWY-6708;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39 "Ubiquinol-8 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_014295648.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_014298522.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_008545027.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053595137.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_008544778.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_008558401.1 11 Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-5675;MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II" XP_014296840.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_053596498.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_008559462.1 60 KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;Reactome: R-HSA-77285;KEGG: 00280+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7778;Reactome: R-HSA-77348;MetaCyc: PWY-6435;KEGG: 00071+4.2.1.17+1.1.1.211;Reactome: R-HSA-77346;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5136;KEGG: 00592+4.2.1.17;Reactome: R-HSA-1482798;Reactome: R-HSA-77350;MetaCyc: PWY-5138;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7726;Reactome: R-HSA-77288;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00362+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7606;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6944;Reactome: R-HSA-77310;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211 "Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Caprolactam degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Valine, leucine and isoleucine degradation";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"2-methylpropene degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Acyl chain remodeling of CL";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Geraniol degradation";"Fatty acid salvage";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid degradation";"Fatty acid elongation";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fermentation to 2-methylbutanoate";"Geraniol degradation";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid degradation";"Phenylalanine metabolism";"Lysine degradation";"Aminobenzoate degradation";"Caprolactam degradation";"Benzoate degradation";"Butanoate metabolism";"Butanoate metabolism";"Tryptophan metabolism";"Pyruvate fermentation to butanol I";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Fatty acid elongation" XP_008553809.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014296592.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" XP_008544497.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_008550254.1 8 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism" XP_008546263.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_053598097.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-7187;Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7184 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_008556470.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014295852.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_008556269.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" XP_014296809.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014295048.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053599119.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_008553840.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008551625.1 8 MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268 "Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_053594820.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053598365.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_014297163.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_008557058.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008555948.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_008557532.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_014300674.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_008548642.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014294838.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_008547382.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_008551879.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_014299114.1 11 Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_053596027.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008543380.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_053594138.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_008544028.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008545140.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014298703.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_053596804.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_008551329.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008547204.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_053597282.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_053592955.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008552106.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053596502.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_008555215.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008552685.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014296919.1 9 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"tRNA modification in the nucleus and cytosol" XP_008555375.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" XP_008550247.1 8 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_008545795.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_053594059.1 14 MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972 "Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)" XP_053596867.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_053597095.1 11 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_008559127.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER" XP_008544111.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008560297.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_008549003.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008548484.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008548634.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_053598402.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014298235.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_053593614.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723 "Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation" XP_008545899.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053596914.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_008551478.1 11 Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043 "Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus" XP_008555893.1 1 Reactome: R-HSA-73614 "Pyrimidine salvage" XP_053596795.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_053593339.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008544991.1 10 Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human papillomavirus infection";"Thermogenesis";"Recycling pathway of L1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_053598793.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008554441.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700 "Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_008558555.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_053595584.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008551769.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" XP_014297141.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008545502.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_053598379.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_053598829.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586 "RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Meiotic recombination";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence" XP_008550556.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_008556315.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014295979.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008545726.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008553233.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_008548319.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_053597841.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014299940.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_053595013.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053593014.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_053598933.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008544966.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_053595974.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_053593207.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_053596673.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_014295589.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008543074.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053594660.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008550178.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_053594513.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_014298374.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_008543307.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008543913.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008546891.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_053593859.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014299761.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors" XP_053595968.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_053597283.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_008556889.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008558931.1 26 Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568 "Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase" XP_008557533.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008547383.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_008547391.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_053595300.1 26 Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-5621575 "FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling" XP_008547539.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_008547745.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746 "NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein" XP_053598451.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_053594835.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008551630.1 7 KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-7586 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_014297162.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_008558000.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008544707.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_053598271.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008559398.1 5 Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage" XP_008560552.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_053596551.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008557106.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_053593860.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_053596708.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_008548371.1 5 KEGG: 00562+3.1.3.64;MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane" XP_014295911.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_053597608.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719 "CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors" XP_053594999.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_008543331.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008548211.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_008548043.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_008547800.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7587 "Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)" XP_008557021.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_053599210.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695 "Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events" XP_014296581.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014299647.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_008552281.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_008556071.1 12 KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362 "Sulfur metabolism";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS" XP_008558049.1 37 Reactome: R-HSA-4551638;Reactome: R-HSA-9639288;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-204005;Reactome: R-HSA-5578749;Reactome: R-HSA-983170;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-2132295;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025 "SUMOylation of chromatin organization proteins";"Amino acids regulate mTORC1";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"COPII-mediated vesicle transport";"Transcriptional regulation by small RNAs";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"MHC class II antigen presentation";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation" XP_053594967.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008551464.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_008550897.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_053594224.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008548155.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008557085.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_014298493.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008557414.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_008544051.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014295166.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008551030.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014297253.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008545708.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167238 "RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation" XP_053599138.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008545551.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053595349.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014298310.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014296336.1 13 KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_014300541.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053593161.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763 "DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation" XP_008545616.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_008548548.1 7 Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_008546076.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_008557638.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008560846.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008545970.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_008550079.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053593070.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_008560021.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_053594888.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_053592804.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290 "O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_053595676.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008548647.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053595712.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_008557847.1 24 Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-8964616 "G-protein activation";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42" XP_008546448.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_053595157.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_053593818.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008553427.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008549481.1 13 Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883 "Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II" XP_008543878.1 14 MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589 "Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)" XP_008559529.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008544080.1 13 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2024101 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"CS/DS degradation" XP_053596970.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_008551271.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014297477.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_008560771.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008544516.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_053597716.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_008559108.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_053599185.1 4 Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50 "Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_014296597.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_008544492.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_053598480.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008560389.1 5 KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_014295187.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_014298489.2 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_008545564.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829 "MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_008550881.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008550893.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_008557038.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_053595132.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008548761.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_053594963.1 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;MetaCyc: PWY-7919 "N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)" XP_008550215.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_053598692.1 7 MetaCyc: PWY-6692;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-3781;Reactome: R-HSA-6799198;MetaCyc: PWY-4302 "Fe(II) oxidation";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)" XP_014297257.1 1 Reactome: R-HSA-419771 "Opsins" XP_053594986.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_053594158.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_014295542.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008543586.1 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559 "Gamma-glutamyl cycle";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway" XP_008554656.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_053594870.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690 "Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"HCMV Early Events" XP_008553166.2 3 KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3 "Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism" XP_008550243.1 12 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-447038 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Trafficking of AMPA receptors";"NrCAM interactions" XP_014296309.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_053597363.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_008547263.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_008544810.1 9 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription" XP_008559123.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_008545988.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_053599039.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_014298288.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_008557342.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014299615.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_014299034.1 18 MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_014298603.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008550611.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_008546204.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_008545677.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_008555897.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_014295412.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053596077.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_053594018.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597027.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_008547137.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_008558520.1 4 KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_014296856.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_008551402.1 42 KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7216;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-6946;MetaCyc: PWY-6883;MetaCyc: PWY-5789;MetaCyc: PWY-7778;MetaCyc: PWY-6945;MetaCyc: PWY-6944;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7656;MetaCyc: PWY-1361;KEGG: 00410+4.2.1.17 "Geraniol degradation";"Butanoate metabolism";"Fatty acid salvage";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"Fatty acid elongation";"Toluene degradation";"Fermentation to 2-methylbutanoate";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Propanoate metabolism";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Lysine degradation";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Aminobenzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"2-methylpropene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Caprolactam degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"beta-Alanine metabolism" XP_008556611.2 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_008550594.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" XP_008548909.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_008553186.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_008555869.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014300562.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_053593142.1 16 Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-1257604 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"RET signaling";"G alpha (q) signalling events";"GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling" XP_008546518.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053594618.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_053597777.1 6 MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17 "Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation" XP_053598937.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_008548358.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014299692.2 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends" XP_014298121.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053592920.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_053597358.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_008558065.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008560767.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_014300483.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_008547046.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_008544301.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008555570.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)" XP_053598717.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_008546069.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_008550066.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053595669.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008558397.1 12 KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-7343 "Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I" XP_008548777.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008559995.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053593709.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_014298048.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014296576.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_053595097.1 11 Reactome: R-HSA-389948;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-909733;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-210990;Reactome: R-HSA-512988 "PD-1 signaling";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"Interferon alpha/beta signaling";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"PECAM1 interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_053597909.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_014300466.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_053598152.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_008543997.1 5 Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfur metabolism" XP_014294970.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_008553447.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008552872.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_008550666.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008550749.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053593942.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014295430.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014298837.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008545858.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008545042.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_053598263.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_053599141.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_008555227.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_008546097.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_008550683.1 11 Reactome: R-HSA-512988;Reactome: R-HSA-210990;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-909733;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-877312 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"PECAM1 interactions";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"Interferon alpha/beta signaling";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Platelet sensitization by LDL";"PD-1 signaling";"Regulation of IFNG signaling" XP_053595598.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008544187.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_008544236.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_008546650.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053595428.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_053593656.1 8 Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-6174 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)" XP_014295434.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014295522.1 7 Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_008544832.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2024096 "HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG degradation" XP_008558242.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053596956.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008548363.1 13 Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8964038 "Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"LDL clearance" XP_008560823.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550845.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053598101.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008558830.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_008556816.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053595957.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014299507.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_008544596.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008552377.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008551391.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP" XP_008555687.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_008545174.2 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_008559384.1 6 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)" XP_008552004.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_008556372.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_008545096.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008552827.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_014298801.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;Reactome: R-HSA-1433557;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1 "Thermogenesis";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"Signaling by SCF-KIT";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway" XP_014298357.1 3 Reactome: R-HSA-5576890;Reactome: R-HSA-5576893;Reactome: R-HSA-1296072 "Phase 3 - rapid repolarisation";"Phase 2 - plateau phase";"Voltage gated Potassium channels" XP_008555588.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008547692.1 8 Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900 "EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4" XP_008549149.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014298417.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593961.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053598776.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008550295.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_053593736.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_008544561.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_008558296.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_008547480.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_008545061.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008555978.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_014294886.1 57 Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling" XP_008560906.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-3371571 "Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation" XP_008545696.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_008547464.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_014295728.1 7 KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_008546238.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430 "Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_008554587.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_008556295.2 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_008561073.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_008554438.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_053596096.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_008555087.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053596170.1 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates" XP_053596747.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008547030.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_053597120.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008554203.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_008544748.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053598012.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_053594163.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008560524.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008556984.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702 "SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands" XP_008552373.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_008553434.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008555433.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_053596654.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_053593954.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053595953.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_053595811.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171 "ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions" XP_008552799.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_014294899.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053597155.1 6 MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-8088 "L-lysine biosynthesis VI";"Lysine biosynthesis";"L-lysine biosynthesis III";"Monobactam biosynthesis";"L-lysine biosynthesis II";"Dipicolinate biosynthesis" XP_014298353.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008545054.1 9 Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Macroautophagy";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling" XP_053595221.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_008553706.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008548008.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_008553059.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6" XP_008559147.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_008551026.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008556574.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_053595168.1 7 MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_008557062.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008557524.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008550401.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008552939.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex" XP_008555535.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_053597043.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_053595285.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014297759.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_053596439.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_008560316.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_008543653.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014296171.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-1445148 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_053596689.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_008554583.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_053593441.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_008555902.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_008549801.1 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis" XP_053598366.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_053596321.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097 "Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway" XP_008548862.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" XP_008560872.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_053596871.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_008553084.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014296430.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_008552767.1 5 Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014296706.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_008554207.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_008556308.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_014299722.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053598391.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_008554485.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008547451.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_053594167.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_008556762.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008553513.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053596715.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014296814.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008546174.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_053597034.1 7 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_008551263.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation" XP_053597615.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-877300 "Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling" XP_008556067.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_008543925.1 18 KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417 "Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" XP_053594971.1 13 KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-5690 "Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)" XP_008558381.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_008556588.2 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_014296224.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_008557939.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_008547725.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008555440.2 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_008545734.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_008547829.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_008550312.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_008551137.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_014299363.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_053593462.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_008546879.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_053597319.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244 "NrCAM interactions";"Trafficking of AMPA receptors";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation" XP_053594581.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_008556699.1 42 Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-110331;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-427413;Reactome: R-HSA-201722 "Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Cleavage of the damaged purine";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Meiotic recombination";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex" XP_008558325.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_008554860.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008557213.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_008547379.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_008551882.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_053598133.1 7 Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-983231 "HDACs deacetylate histones";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production" XP_008558029.1 12 Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-75893;Reactome: R-HSA-1251985 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TNF signaling";"Nuclear signaling by ERBB4" XP_053596406.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008544166.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480 "VLDL clearance";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"VLDL assembly";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"LDL clearance";"Chylomicron clearance";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Scavenging by Class A Receptors" XP_008547075.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008550978.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014299498.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_053595625.1 17 MetaCyc: PWY-6679;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722 "Jadomycin biosynthesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Candicidin biosynthesis" XP_014300037.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_053595775.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_008544191.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_008544183.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053598506.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_053592821.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008554189.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs" XP_008561016.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053595693.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Transcription of the HIV genome" XP_008560827.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595431.1 7 KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism" XP_053596994.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_053595329.1 4 Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-947581 "Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis" XP_008549048.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-8955332 "Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin" XP_008558107.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008546769.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation" XP_008558765.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008547746.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_008556763.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008553512.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_008560741.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_014297447.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053596940.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_053597188.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008557436.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_008553461.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_053593756.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014297475.2 14 Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_053594836.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_008551613.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008550791.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_014299073.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_053597042.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_014295603.1 6 MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"N-acetyl-D-galactosamine degradation" XP_008546258.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" XP_008551584.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_008543487.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_053599233.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_053598617.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_008555490.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_008557063.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014300733.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014298352.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008554318.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053594477.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008546797.1 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_008552822.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008548156.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008548988.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_053595952.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_008557086.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_053593609.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_053598448.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_014296138.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_053597096.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_008551300.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_008552436.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system" XP_008555376.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008557409.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_008560574.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"MASTL Facilitates Mitotic Progression";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_053595630.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008543126.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008557918.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_053597747.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_008554927.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596120.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008553718.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_053596647.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008557372.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_008553210.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_008556316.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_008558330.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_008556276.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_053596796.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_014299362.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_053593463.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_053595464.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008551645.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008550907.1 5 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-8963896;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"HDL assembly";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_008545838.1 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport" XP_008547730.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053594530.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008555928.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_008544852.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_053593486.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_008558178.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_053593636.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008545647.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_008545120.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" NP_001401786.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008551349.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_008560960.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008544965.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_008551262.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation" XP_053597871.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008544833.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_008558243.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014295493.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014300090.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014295481.1 5 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation" XP_008556245.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_008560822.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596821.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_053597439.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008545754.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596789.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_008553760.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008554134.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014298344.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_008554549.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_053596643.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_053595944.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_008557308.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-419771 "Neddylation";"Opsins" XP_008550490.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_053593529.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014299772.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-438066 "Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation" XP_014299970.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053598153.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_008559922.1 12 Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606 "HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_008545821.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053597089.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2644606 "Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014295031.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008555345.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008550903.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607 "Cleavage of the damaged purine";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Meiotic recombination";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends" XP_014296855.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_014297513.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008553784.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008550317.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_008550457.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008544294.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_014296759.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_053594141.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_053595451.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_053598300.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008556524.1 10 KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;MetaCyc: PWY-5691 "Purine metabolism";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Neutrophil degranulation";"Urate conversion to allantoin III";"Urate conversion to allantoin I" XP_008543644.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_008556494.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_008555931.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_053595675.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_008556767.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_008549412.1 10 KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_053599005.1 13 Reactome: R-HSA-9649948;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Signaling downstream of RAS mutants";"Human papillomavirus infection";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008555453.1 7 MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363 "Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_014295824.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008549426.1 4 Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-196741 "Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_053598013.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_053595124.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014296335.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II" XP_014297443.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008544149.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014294862.1 30 Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-111447;Reactome: R-HSA-211163;Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-199418;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-8948751;Reactome: R-HSA-1358803;Reactome: R-HSA-6804758;Reactome: R-HSA-198323;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400 "CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Regulation of TP53 Degradation";"Activation of BAD and translocation to mitochondria";"AKT-mediated inactivation of FOXO1A";"RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"CTLA4 inhibitory signaling";"Regulation of PTEN stability and activity";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Acetylation";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_014295374.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_053597406.1 3 Reactome: R-HSA-189085;Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014295007.1 5 Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681 "XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT" XP_008557568.1 2 Reactome: R-HSA-192456;Reactome: R-HSA-975634 "Digestion of dietary lipid";"Retinoid metabolism and transport" XP_053597994.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290 "RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation" XP_008555555.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-176187 "Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress" XP_053595219.1 20 MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II" XP_053593794.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008546047.2 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_008544844.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008551617.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_053593195.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_053595829.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008553314.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008545634.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008545015.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008559587.1 8 MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-7573;Reactome: R-HSA-6787639 "GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis" XP_008543491.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053597114.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_014299077.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008548723.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008553489.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_008556939.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_008546675.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_053597715.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_053594253.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008546124.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_053596615.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events" XP_008546781.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008558375.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_008546219.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-68877 "Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Kinesins";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase" XP_053598559.1 8 KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism" XP_008554655.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_008547693.1 8 Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis" XP_008543466.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008546548.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_053598241.1 5 Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" XP_008548194.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_008556823.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_008550216.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_008558825.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168333 "SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_008550306.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_008545561.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_053599219.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_008559555.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008552926.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_008551274.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_008559273.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_053594110.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_008554437.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014296382.1 27 Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-3371453;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5358751;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-198323;Reactome: R-HSA-5358747 "Beta-catenin phosphorylation cascade";"Thermogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Degradation of GLI2 by the proteasome";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Regulation of HSF1-mediated heat shock response";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"S45 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Human papillomavirus infection";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"CRMPs in Sema3A signaling";"AKT phosphorylates targets in the cytosol";"S33 mutants of beta-catenin aren't phosphorylated" XP_053595005.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation" XP_008549459.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Kinesins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_008557364.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_053594957.1 6 MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism" XP_008549615.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_008546186.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs" XP_008546958.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_053595472.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" XP_008543658.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008552504.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_014300815.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_008553204.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_053592801.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_053597852.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008560024.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_014298909.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_053596561.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008552839.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_053594730.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_008560351.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_053596352.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_053593164.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763 "DAG and IP3 signaling";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation" XP_008543532.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014298418.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008554312.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" XP_053596426.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_008558756.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_008546005.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008551639.1 8 MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901 "Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation" XP_008554326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596412.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling" XP_008544696.1 19 MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7205;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_008552828.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_053597476.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_053598904.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053594990.1 4 Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9 "Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate" XP_008547592.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_014299751.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837 "Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases" XP_008550860.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_053598370.1 10 Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459 "MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_008560479.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008554782.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008553157.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_053598442.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008550421.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_014298120.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540 "Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1" XP_008555196.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_053598210.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_008544188.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_053595427.1 11 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_008543230.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_008555228.1 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway" XP_008546098.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_014298838.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008550973.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008549646.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008551759.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008557710.1 4 Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_008556976.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_014300021.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_008547290.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_008558565.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008557926.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014296712.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008546979.2 9 Reactome: R-HSA-9656256;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9656255 "Defective OGG1 Substrate Processing";"Defective OGG1 Localization";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding" XP_008554227.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014296726.1 4 Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631 "MET activates RAP1 and RAC1";"MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL" XP_008553448.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008557192.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008556878.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014299496.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_014299368.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_053594050.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_008546427.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_008554817.1 7 Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-429947 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Deadenylation of mRNA" XP_008557828.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008555401.3 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_008553887.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_008560302.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952 "Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation" XP_008555720.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_008545542.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_014300533.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053594069.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_008556010.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008549211.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008544042.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_008549371.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008559791.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_053597357.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008560768.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053592833.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008560192.1 9 Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_053598185.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_008548368.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_008560828.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053597844.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_053598784.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_008554444.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580 "Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence" XP_014299489.2 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_008555755.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_053595423.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation" XP_014300038.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_053594025.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_008544135.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008557284.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_053598121.1 5 KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_053597534.1 4 MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163 "Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism" XP_008557302.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008549796.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014296866.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_008556331.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008554951.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008560504.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-381042 "Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression" XP_014296045.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008551138.1 18 MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Ether lipid metabolism" XP_008556429.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053594431.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008543785.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008544819.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion" XP_014300537.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008560710.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_053598855.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_053596911.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008553883.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466 "Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis" XP_008547253.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053598760.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008553891.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_053594625.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_008543671.1 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" XP_014296153.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_008547575.1 10 KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I" XP_008548481.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_008553645.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008556945.1 5 Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895 "Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism" XP_008546525.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008557351.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008547417.2 14 Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969 "Respiratory electron transport";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_008554535.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014297506.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008551461.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_053598941.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_008561220.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008550670.1 7 MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25 "Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism" XP_053593729.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_008546408.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053594168.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_008557024.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_008556851.1 5 KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_008553560.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_008550181.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014296584.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation" XP_008555614.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_008559277.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014297133.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_008551526.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008548751.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_008554433.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014299982.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_053593825.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_008557411.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008549358.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014298015.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_053598454.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_008553974.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_008557175.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_008559524.2 5 Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" XP_014299764.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_014294991.1 5 KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578 "Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_008560803.1 56 Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-349425 "Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1" XP_053593079.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_053595167.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999 "Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_008548007.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_008555339.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008548374.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014300269.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055 "Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis" XP_008558794.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008549742.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008551388.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" NP_001401802.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014296152.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_053599093.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6 "Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism" XP_014295109.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_008553137.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014300019.1 20 MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-735 "Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis" XP_014296291.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_008544047.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_008550359.1 22 Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated" XP_008552010.1 11 Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-975634 "A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport" XP_008560228.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008543250.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008544936.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008547252.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_008559444.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008550908.1 5 Reactome: R-HSA-2243919;Reactome: R-HSA-8963896;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"HDL assembly";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_014299651.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014300334.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" XP_053599025.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_008552328.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC" XP_008543254.2 1 MetaCyc: PWY-7379 "Mrna capping II" XP_008554376.1 4 Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693;Reactome: R-HSA-5674400 "Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer" XP_014295027.1 12 MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1861;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis" XP_008551739.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008550419.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_008547166.2 5 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-4655427 "DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins" XP_008545182.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014296717.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch biosynthesis" XP_053593103.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" XP_008549734.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008549229.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008550806.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_053597748.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_008554928.1 8 MetaCyc: PWY-7199;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;MetaCyc: PWY-7193 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I" XP_008555280.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008558805.1 8 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_053597209.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_053598888.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_053595356.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008550202.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_008544647.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_008546809.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_053595416.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014296882.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008561031.1 6 KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)" XP_008546705.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_053595592.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944 "Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2" XP_053599174.1 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_008558056.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_053595422.1 14 MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_008549715.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110362 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" XP_053592832.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014300275.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_014297382.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_014300315.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008549114.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008553152.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_014296137.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_053598447.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_008556192.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008549743.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008559535.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_008548987.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_008547597.1 7 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-171319 "UCH proteinases";"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase" XP_008556378.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_014297712.1 5 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-8963896;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"HDL assembly";"Crosslinking of collagen fibrils" XP_008549050.2 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_014299602.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_008554277.1 4 KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_008551171.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_008555582.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008554317.1 10 MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153 "3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection" XP_053594478.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_008551684.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" XP_008560668.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_008560802.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_008561007.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-179409 "Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A" XP_008548577.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053594046.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_014300671.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_008559845.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_008543488.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008548678.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" XP_053597857.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008548220.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008548446.1 33 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3108214 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins" XP_008543361.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" XP_053598870.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053593830.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_014297887.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008547098.1 14 MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-4302;MetaCyc: PWY-3781 "Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)" XP_008546836.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346 "HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis" XP_053594750.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_053594952.1 6 KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346 "Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_053594865.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN" XP_008554432.1 4 Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9 "Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism" XP_008552864.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_014299983.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_008550471.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_053593261.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008550134.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex" XP_053593128.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053594769.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008547569.1 5 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008549654.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008556926.1 3 KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" XP_008550251.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism" XP_008558961.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008551084.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014299573.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_008554520.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008560099.3 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053598018.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_008543685.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine" XP_008554555.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_053598659.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_008547581.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008558989.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008557599.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014296363.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008552193.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_053594829.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008546547.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008554907.1 7 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-140837 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation" XP_053596413.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-167590 "Ion channel transport";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation" XP_053599110.1 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Galactose metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism" XP_014299220.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_008559978.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_053598355.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008548731.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053596353.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008546575.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008553745.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_008548573.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase" XP_008557945.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008547525.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_014299078.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053597853.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008551320.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_053597911.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_008552125.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053593711.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_053595473.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_008550788.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_014296144.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_053595985.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_053597344.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008548868.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014297645.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_008561165.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014296383.1 9 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008555419.1 4 Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880 "Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases" XP_008545100.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053596844.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014296745.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_008559326.1 5 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis" XP_053596534.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008556302.1 9 Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1 "Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)" XP_008548111.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" XP_053598060.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008543354.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008544484.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_014297349.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053593131.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008556768.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_053597166.1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5696397 "Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_053592853.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_008546141.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_014295367.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531 "Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus" XP_008560169.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008551447.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_008552068.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008552438.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_014300532.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053598119.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008550318.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014300842.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_008557193.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008553506.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_008555471.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_008545445.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014297613.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008548324.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008556024.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008543293.1 13 MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_008543281.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008543719.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008545232.2 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-912446 "Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination" XP_008555714.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788 "HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling" XP_053599050.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008550770.1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" XP_008554931.1 20 Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "Macroautophagy";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"mTOR signalling";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" XP_008550620.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_053596543.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008554766.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_053594451.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_053595394.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014296267.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_008552206.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_008547408.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014298734.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747 "Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated" XP_008547233.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_053598443.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014298135.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053598999.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008555500.1 18 MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1 "Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_008548333.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_008553793.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_008557449.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008549677.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_008545374.1 5 Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-193048 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis" XP_008547999.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053594849.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053593273.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_008547835.1 3 KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE" XP_008544266.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_008549578.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014299240.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008553829.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_008545138.2 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_053597707.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_008558973.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_008546489.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_008557733.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014298867.1 8 MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5049 "Betalamic acid biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II" XP_008552744.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053594539.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_008558566.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008558014.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_008555934.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" NP_001401753.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_053598408.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008554711.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_014298502.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_008551340.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014299561.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_008545129.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-350054 "Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway" XP_008559850.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_008552653.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_008559164.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_014299337.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014295484.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_008547224.1 3 Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999 "Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" XP_014296933.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008558563.2 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_053597051.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_014296725.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014298673.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008545607.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008553402.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_053595639.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014297879.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_053595489.1 26 Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408 "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation" XP_008550172.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_008554131.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_008558035.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_008552519.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_008547171.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008554029.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008557145.1 14 Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862 "EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_008560032.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_008555943.1 5 MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168 "Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)" XP_008545523.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_008543494.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008552925.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_053594924.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695 "Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation" XP_008559556.1 30 Reactome: R-HSA-1358803;Reactome: R-HSA-6804758;Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69656;Reactome: R-HSA-389513;Reactome: R-HSA-8948751;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-211163;Reactome: R-HSA-111447;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-199418;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693 "Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Acetylation";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Cyclin A:Cdk2-associated events at S phase entry";"CTLA4 inhibitory signaling";"Regulation of PTEN stability and activity";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"AKT-mediated inactivation of FOXO1A";"Activation of BAD and translocation to mitochondria";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Negative regulation of the PI3K/AKT network";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus" XP_008560657.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_008548191.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_008549616.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_014300816.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_008558189.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_008546606.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_008549970.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159231 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_053594267.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_008560558.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_008546784.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008552981.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008560701.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_008552449.1 12 KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-7118 "Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Methane metabolism";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol" XP_008554107.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008548344.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway" XP_053597868.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053595121.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_008547660.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation" XP_008548911.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_008545461.2 11 KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2 "Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_008547355.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_053593766.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053593649.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008560482.1 5 Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603 "TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases" XP_008545904.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008554779.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053596631.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_053596523.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008554875.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942 "Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism" XP_053595606.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547415.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_008544841.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_008553311.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008547084.1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244 "Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Collagen degradation";"NCAM1 interactions";"Signaling by PDGF";"Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization" XP_053596425.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008548406.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053596595.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008555467.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_053597475.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_053599132.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008554325.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595268.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008546759.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_008546006.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008556930.1 7 KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis" XP_008544027.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053594137.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_008558720.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_053596450.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014299186.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008557632.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053599153.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_053594286.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008550915.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_053596028.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008548890.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_008555947.1 22 MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7619 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis" XP_008559594.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_014295761.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191 "Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Neutrophil degranulation";"Synthesis of PC" XP_014296030.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008557690.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053599045.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_053593812.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008548187.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_053596310.1 10 Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs" XP_008554103.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008559011.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008544628.3 7 KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" XP_008551971.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane" XP_008546820.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification" XP_014297403.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_053598098.1 10 MetaCyc: PWY-7199;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7184;Reactome: R-HSA-499943;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-3841;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_014299472.2 3 Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_008549249.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_053596628.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_053597728.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_008551244.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_008544498.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_053596497.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_008544140.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_008549708.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008557032.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_053595138.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_008545028.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_008544777.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_014294852.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550732.2 13 KEGG: 00052+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Glycosphingolipid metabolism";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Keratan sulfate degradation";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation" XP_053595210.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014294965.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_053598427.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_008557090.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296480.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_008553797.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008549673.1 39 Reactome: R-HSA-5654706;Reactome: R-HSA-5654687;Reactome: R-HSA-5654710;Reactome: R-HSA-190375;Reactome: R-HSA-6811558;Reactome: R-HSA-5654733;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-190373;Reactome: R-HSA-5654227;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-1257604;Reactome: R-HSA-1839130;Reactome: R-HSA-5658623;Reactome: R-HSA-2219530;Reactome: R-HSA-5654720;Reactome: R-HSA-1839122;Reactome: R-HSA-5654727;Reactome: R-HSA-5655302;Reactome: R-HSA-5654712;Reactome: R-HSA-5654688;Reactome: R-HSA-2033519;Reactome: R-HSA-5654699;Reactome: R-HSA-5654219;Reactome: R-HSA-190372;Reactome: R-HSA-8853338;Reactome: R-HSA-190322;Reactome: R-HSA-5654719;Reactome: R-HSA-5655253;Reactome: R-HSA-5654689;Reactome: R-HSA-5654228;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654704;Reactome: R-HSA-5654221;Reactome: R-HSA-2033514;Reactome: R-HSA-190371 "FRS-mediated FGFR3 signaling";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR3";"FGFR2c ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"FGFR1c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"PIP3 activates AKT signaling";"Signaling by activated point mutants of FGFR3";"FGFRL1 modulation of FGFR1 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR4";"Signaling by activated point mutants of FGFR1";"Negative regulation of FGFR2 signaling";"Signaling by FGFR1 in disease";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR1";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade: FGFR1";"FGFR3c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"FGFR4 ligand binding and activation";"SHC-mediated cascade:FGFR4";"Signaling by FGFR2 in disease";"PI-3K cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR4";"PI3K Cascade";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR2";"FGFR3 mutant receptor activation";"FGFR3b ligand binding and activation" XP_008543377.1 14 MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-8052 "Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis" XP_008549723.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_008550108.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_008559729.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008555756.1 7 Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_008548337.1 14 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852;Reactome: R-HSA-9648025 "Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Macroautophagy";"EML4 and NUDC in mitotic spindle formation" XP_053598237.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_008551811.3 1 Reactome: R-HSA-156588 "Glucuronidation" XP_053597703.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" XP_008544503.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_008545780.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008559893.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008561149.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008551894.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053593903.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_008557348.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_053595904.1 10 MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225 "Urate conversion to allantoin I";"Urate conversion to allantoin III";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Amyloid fiber formation" XP_008556487.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" NP_001401757.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014295909.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_014297097.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_053595512.1 7 MetaCyc: PWY-7295;MetaCyc: PWY-7118;MetaCyc: PWY-7294;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7854 "L-arabinose degradation IV";"Chitin degradation to ethanol";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_053593457.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_053596288.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_014300741.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008559825.1 24 Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-8964616 "G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42" XP_008546595.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_008546388.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_053594026.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_008545572.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_014300395.1 6 Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693 "FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling" XP_053594012.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409 "Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_008555127.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837 "Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation" XP_008552482.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_008547986.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_008546461.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008543786.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008545855.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008549073.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_008559079.1 32 Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-77075 "HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_053598340.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_008554892.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_053594776.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_014300568.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_053594626.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex" XP_008546512.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes" XP_008548561.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" XP_008547963.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_008556946.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008553155.2 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_008544716.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_008544672.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_008554540.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_008544722.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" NP_001401790.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014296775.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation" XP_053599137.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053596874.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008549027.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053594153.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555 "PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events" XP_014297933.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5658034 "Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Activation of SMO";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np" XP_053597824.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_008552753.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_008554424.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_008546814.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_014295406.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_053597374.1 6 MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA" XP_008549804.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_008559846.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_014297793.1 5 Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32 "Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_008550898.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_053594045.1 13 MetaCyc: PWY-6545;MetaCyc: PWY-7187;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine catabolism";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Purine metabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_014295994.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008544200.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_053592949.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_053595545.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_053598394.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_008549109.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008560538.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_053595739.1 11 Reactome: R-HSA-109704;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-168138 "PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Toll Like Receptor 9 (TLR9) Cascade" XP_008554011.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014299648.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008560488.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008549498.1 11 Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_014295114.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_053595224.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_008544362.1 34 Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-9639288;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-5578749 "snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Amino acids regulate mTORC1";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs" XP_014297402.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_008549627.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_008543323.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008544708.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014296025.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695 "G alpha (q) signalling events";"Signaling by SCF-KIT";"RET signaling";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling" XP_053596651.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_008553329.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_053593813.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014295715.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243 "Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008545179.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008554611.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008547639.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008548543.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008557633.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014296081.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_008560732.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008550177.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053596966.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_014299390.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008543308.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346 "CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis" XP_008546660.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053593208.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_008547855.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053598253.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_014295689.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008553407.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008549072.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_053597425.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis" XP_053595684.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_008551290.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_053598985.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_008553811.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008556653.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756 "ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation" XP_053595059.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_053599026.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_053594974.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_008545966.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008555579.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_008557644.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_053594013.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase" XP_008559830.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_008551477.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR" XP_053595355.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_008544914.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363 "Streptomycin biosynthesis";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_014298608.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008560298.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_053597031.1 15 MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)" XP_014298862.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242 "Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_008547268.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_008545475.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_053596602.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008559892.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_014300316.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008546706.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_008550248.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_008549722.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014294979.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008551938.1 7 KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-6614;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-3841 "One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)" XP_014296990.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008550173.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014296792.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008558020.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008548357.1 14 KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-7767;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5078;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-5104 "Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine degradation II";"L-valine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis IV" XP_008555736.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-450520 "EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA" XP_008556590.3 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_053598257.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_053594617.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_008560644.1 9 MetaCyc: PWY-241;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle" XP_053597778.1 5 Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434 "Kinesins";"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008555404.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_053598938.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_008553110.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008546517.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_053593687.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008558278.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_014297480.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053595320.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_053599144.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_053593588.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_008550511.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_008560044.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_014299515.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008552205.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_053596078.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_053593452.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008544304.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" NP_001401752.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053593272.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_014298136.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053593326.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_053597270.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008557001.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_008547442.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_053598836.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008554869.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_008554160.2 6 Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916 "Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Other glycan degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation" XP_014295661.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008543440.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_053598422.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008544580.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_053596680.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_008543704.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_053599133.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053594157.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_053595447.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008554556.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_008543686.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_053598840.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_008560975.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_008548256.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_008544616.1 4 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_053596522.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014296598.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_053598356.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008557946.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008552298.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_008545664.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008558280.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014300213.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_008545430.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_014294890.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053598705.1 11 Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693579 "Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange" XP_008554247.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014296746.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_008553428.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008549399.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_053598104.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008549531.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_053596080.1 11 Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213 "HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs" XP_008546447.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008549773.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_053595158.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008555942.1 5 Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" XP_008559875.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_008545064.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_053594887.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008548547.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232 "Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_014299294.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_008557637.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_053595963.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_053593964.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008556737.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053598809.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_008547875.1 13 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection" XP_008548823.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053598907.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_053596275.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_008554084.1 5 Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038 "ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes" XP_008558793.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053594989.1 4 KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis" XP_008549637.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014295913.1 6 MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_008546215.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_008547325.1 17 Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-111448;Reactome: R-HSA-139915;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis" XP_008553591.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_008546881.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008551494.2 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_008560386.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_053593919.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008560804.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_053596619.1 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_014297500.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_053593167.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-112043 "VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Regulation of insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"PLC beta mediated events" XP_008553485.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_008557531.1 19 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-8876725;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Protein methylation";"Viral mRNA Translation" XP_008546679.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008547381.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_008556673.1 12 KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Rho GTPase cycle";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008545019.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_053594579.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" XP_053598453.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_008556723.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_053596455.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014299004.1 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_008547468.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165 "Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)" XP_008550190.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_008545315.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014299217.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014298491.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053599127.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008550448.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_053595215.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-6837 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_008557367.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_053595375.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_008551457.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_008547107.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008557023.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_014296421.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_008555560.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_014296583.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_008555613.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_008558075.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014300852.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_008560627.1 30 Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-5610783 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Circadian Clock";"Degradation of GLI2 by the proteasome" XP_008544744.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008560498.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-201688 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"WNT mediated activation of DVL" XP_053595679.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94 "Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism" XP_008558402.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008560528.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_008549001.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008548494.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008554119.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_014300390.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008559210.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_008550518.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014296169.2 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_008553884.1 7 MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_008547254.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_008555883.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008549790.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_008559442.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5685939 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" XP_008553306.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_014296859.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_053597085.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_008550382.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053593525.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-983168 "Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053595011.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008544733.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_008551216.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_053593495.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_053593971.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_008554545.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_008560722.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" NP_001401795.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_053598649.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation" XP_053598766.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_053596671.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_008548662.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_008557283.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_014300801.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008552367.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_008554443.1 16 Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580 "TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence" XP_008556551.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_053596343.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_008553755.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_008549269.3 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_053599036.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_008549126.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008549112.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053597843.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008547892.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008548456.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008560283.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_014294877.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_008555887.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_008551000.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_008552528.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008547296.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_014295586.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_008554986.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_008546556.1 27 Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-111367;Reactome: R-HSA-159227;Reactome: R-HSA-77588;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-975956;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-975957;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-674695;Reactome: R-HSA-159230;Reactome: R-HSA-6807505;Reactome: R-HSA-9010553;Reactome: R-HSA-113418 "Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP independent Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Transport of the SLBP Dependant Mature mRNA";"RNA polymerase II transcribes snRNA genes";"Regulation of expression of SLITs and ROBOs";"Formation of the Early Elongation Complex" XP_008547830.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_008551766.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_008550241.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism" XP_008551649.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_014298112.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008560507.1 5 KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)" XP_014296161.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_014299245.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008543187.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008547261.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_053595247.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_008556580.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_008558692.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695 "Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Neutrophil degranulation" XP_014296070.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008553070.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014298790.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_014297582.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008556016.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053596738.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008550974.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008557136.1 29 Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-176187 "Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress" XP_008545118.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_008552027.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_053593427.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_008544997.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053598787.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_053595556.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014296922.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_008545861.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053597847.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008560137.2 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008547509.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008559855.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_008548827.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_053598903.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596905.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053595869.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008545420.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation" XP_053593958.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008548649.2 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_053593186.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014298946.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595346.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008543337.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008559941.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008546180.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_008544657.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_053596557.1 3 Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12 "Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism" XP_008559489.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008560095.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_008558797.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053593163.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-983695 "Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Regulation of insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_014299767.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_014295150.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_008547948.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008554517.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008553142.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport" XP_008560023.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008557627.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_008549585.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008550968.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_014299041.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008543209.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_053599123.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008544057.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_008558750.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_014298637.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_008558952.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053598432.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014296142.1 29 Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_053597269.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008554320.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_053597342.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" XP_008551453.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport" XP_008553088.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_053594996.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_008560841.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_008547410.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008550866.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_053596532.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_008556304.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)" XP_008550645.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" XP_053598520.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism" XP_008557027.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_008551313.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_008558477.3 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" XP_008544482.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053594736.1 11 Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196 "Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling" XP_014295197.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008557386.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053593252.1 3 Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320 "HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH" XP_008549117.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II" XP_053598444.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_008552551.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection" XP_008551401.1 42 MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-6946;MetaCyc: PWY-6883;MetaCyc: PWY-6945;MetaCyc: PWY-7778;MetaCyc: PWY-6435;MetaCyc: PWY-6944;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7654;MetaCyc: PWY-5177;MetaCyc: PWY-1361;MetaCyc: PWY-7656;KEGG: 00410+4.2.1.17 "Fatty acid salvage";"Butanoate metabolism";"Geraniol degradation";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Tryptophan metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid elongation";"Fatty acid degradation";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Pyruvate fermentation to butanol I";"Toluene degradation";"Fermentation to 2-methylbutanoate";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Androstenedione degradation";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Caprolactam degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"beta-Alanine metabolism" XP_008557867.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_053594108.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014297635.1 6 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_008547234.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling" XP_053595393.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008553115.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008556023.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy" XP_053593141.1 16 Reactome: R-HSA-114604;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-416476 "GPVI-mediated activation cascade";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"RET signaling";"G alpha (q) signalling events" XP_008547079.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014300561.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_008554121.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053597553.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014296714.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen synthesis" XP_008558693.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008559888.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_008555716.2 8 Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_008548323.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014300337.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_008548873.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008553839.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_053598223.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_053597315.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14 "Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation" XP_014298113.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008555506.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014295351.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563 "Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription" XP_053594529.1 10 KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis" XP_008547729.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014300748.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I" XP_008558775.1 5 KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis" XP_008553735.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053594943.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_053597455.1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_008547893.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053599056.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053597619.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946 "RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants" XP_053592854.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_008554962.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053598295.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_008545830.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008551782.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_008557899.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582 "Meiotic recombination";"PKMTs methylate histone lysines";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"DNA methylation";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Packaging Of Telomere Ends";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)" XP_008550882.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_053597889.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_008543515.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008552073.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_014295479.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_008548817.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_008548308.1 7 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism" XP_008560772.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_008551312.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_008549657.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation" XP_014297189.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_008558168.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008544483.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008556266.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_008545414.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014295541.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008559517.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_008553419.1 4 MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_008557362.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" XP_053597785.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014297306.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008558811.1 10 MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation" XP_008544466.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_008553908.1 4 KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_014296202.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_053598691.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014299226.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008553143.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008554039.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053597854.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008544463.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014296655.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_053596354.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014296419.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053593162.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-112043;Reactome: R-HSA-2029485 "FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Regulation of insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis" XP_014300542.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008545621.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236 "HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"PKMTs methylate histone lysines";"Meiotic recombination";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"DNA methylation";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_008559870.1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236 "SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_008553055.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_053596414.1 8 Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9636467 "Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Blockage of phagosome acidification" XP_053598083.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_053598902.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008545435.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_008555366.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_014296364.2 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008559415.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008556287.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_008552077.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008556136.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_053598978.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008550924.1 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_008557022.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_008550133.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_053594040.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014296582.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion" XP_008555612.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_008552282.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_053595892.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008551700.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053596847.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008546509.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_053593798.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_008543417.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_008559660.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_053598437.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014296147.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008550506.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008553278.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_053598687.1 15 Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-9018519 "RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression" XP_008544848.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008559355.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008545638.1 15 Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_053594127.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_053594640.1 13 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_008555012.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_014300340.2 13 Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8866427 "MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation" XP_053597118.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_008555026.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_008553147.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053598452.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_008551683.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_008550299.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_008546892.1 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism" XP_008554512.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053596552.1 10 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "EGFR downregulation";"Negative regulation of MET activity";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_008560551.1 8 Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_008548226.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014296020.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008549145.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation" XP_008543332.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_053593836.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_008553624.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_014295912.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_008555623.2 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_008548212.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_053594756.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_008548198.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008551749.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_053596361.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_008559119.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_008549113.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008546398.3 1 KEGG: 00906+1.23.5.1 "Carotenoid biosynthesis" XP_053597842.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008544992.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_053598980.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053598782.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_008561082.2 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_008554442.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_008550366.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014298737.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221 "RAF activation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway" XP_008546846.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_053596342.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008557863.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" NP_001401716.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008545501.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_014300554.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_008546536.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_008546665.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_014296788.1 9 MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-7852 "Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_008556386.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008557282.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)" XP_008558746.1 6 MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12 "Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis" XP_053595065.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008559224.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008558697.1 11 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5693565 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_008558050.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_008544757.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014300589.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_008553788.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008548877.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_008544601.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053593809.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_008545250.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_053594172.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008559728.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008559999.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_008544298.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008549993.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008546397.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_053595665.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008556777.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008559443.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_053599094.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_008544112.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008555137.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008559835.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053595350.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008556528.1 10 Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;MetaCyc: PWY-5691 "Amyloid fiber formation";"Purine metabolism";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Neutrophil degranulation";"Urate conversion to allantoin III";"Urate conversion to allantoin I" XP_053594036.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_053598401.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008544126.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_008552616.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_053595490.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_014296756.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008551234.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_008559233.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008549239.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_008547401.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_008557858.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation" XP_008558518.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_053594020.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008549074.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_053595682.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014298880.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_008545604.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014300651.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008555865.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205 "Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Purine metabolism" XP_008544218.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_008555750.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_053597086.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053598180.1 10 Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856 "NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling" XP_008544828.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_053599207.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_014297248.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_008558382.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_053594770.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053594147.1 22 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7727 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)" XP_053594620.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_008549181.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_008546490.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_053593496.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_008558017.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008544710.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_008555937.1 5 KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863 "Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis" XP_014295652.1 17 Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167242;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway" XP_008549720.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_053593526.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884 "Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX" XP_008546148.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_053595457.1 7 Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes" XP_053598765.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_008554546.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_008549125.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053599035.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_008548590.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_008559894.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_008555797.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_014298169.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_008557188.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_008549674.1 39 Reactome: R-HSA-5654727;Reactome: R-HSA-1839122;Reactome: R-HSA-5654720;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5658623;Reactome: R-HSA-1839130;Reactome: R-HSA-5654726;Reactome: R-HSA-5654227;Reactome: R-HSA-5654732;Reactome: R-HSA-5654700;Reactome: R-HSA-190373;Reactome: R-HSA-5654695;Reactome: R-HSA-5654733;Reactome: R-HSA-6811558;Reactome: R-HSA-190375;Reactome: R-HSA-5654687;Reactome: R-HSA-5654710;Reactome: R-HSA-5654706;Reactome: R-HSA-190371;Reactome: R-HSA-2033514;Reactome: R-HSA-5654221;Reactome: R-HSA-5654704;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-5654228;Reactome: R-HSA-5654689;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-190322;Reactome: R-HSA-8853338;Reactome: R-HSA-190372;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-2033519;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302 "Negative regulation of FGFR2 signaling";"Signaling by activated point mutants of FGFR1";"PI-3K cascade:FGFR4";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"FGFRL1 modulation of FGFR1 signaling";"Signaling by activated point mutants of FGFR3";"Negative regulation of FGFR1 signaling";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR3 signaling";"FRS-mediated FGFR2 signaling";"FGFR1c ligand binding and activation";"PI-3K cascade:FGFR2";"Negative regulation of FGFR4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR2c ligand binding and activation";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR3";"FRS-mediated FGFR3 signaling";"FGFR3b ligand binding and activation";"FGFR3 mutant receptor activation";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Phospholipase C-mediated cascade, FGFR4";"PI-3K cascade:FGFR1";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"FGFR4 ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"FGFR3c ligand binding and activation";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease" XP_008557956.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110331;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-427413 "HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged purine";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression" XP_014296305.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_014300051.1 13 Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883 "Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II" XP_008549724.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_008548058.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008551679.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_014295037.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199 "Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate" XP_053597436.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053596872.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_053595787.1 34 Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-9639288;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142 "SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Amino acids regulate mTORC1";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins" XP_008554149.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008547326.1 17 Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-139915;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis" XP_008553463.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014300868.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_053597226.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_053597440.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008546812.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_008551611.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_008550793.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_014300602.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014296172.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008549802.1 4 Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847 "UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones" XP_008555901.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_053592877.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053593442.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_008548861.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_053593370.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_053596322.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008555030.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_008553486.1 58 Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-5689901;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Metalloprotease DUBs";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs" XP_008558910.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008558712.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_008556761.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014295992.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053593138.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_014298328.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053595928.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_008558502.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008549395.3 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_053598392.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_008543450.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_008551243.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_008550725.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008560743.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_053595216.1 20 MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337 "6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_014300002.1 3 MetaCyc: PWY-5697;MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism" XP_014299159.1 14 MetaCyc: PWY-5695;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6607;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4 "Inosine 5'-phosphate degradation";"Caffeine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation I";"Drug metabolism - other enzymes";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine metabolism" XP_008558190.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014295112.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_053595222.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858 "Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II" XP_014297404.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_053595376.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_008547588.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053595812.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171 "ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions" XP_008544803.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_014295601.1 6 KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-7395;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_008550075.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008559593.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_008556647.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014299160.1 14 MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6606;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00232+1.17.3.2;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6999;MetaCyc: PWY-6607 "Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Caffeine metabolism";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Drug metabolism - other enzymes";"Purine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation I" XP_053599231.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_008548738.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008553036.1 5 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_008547978.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014296463.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_053597409.1 3 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214;Reactome: R-HSA-189085 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate" XP_014300573.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_008543628.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_008550402.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008553398.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_053599154.1 14 Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_008546928.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008556754.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_053595345.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008549610.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008559569.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_014297997.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_053593268.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595000.1 4 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER" XP_053596906.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008555271.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_008553108.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_008548159.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014298945.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008552229.1 24 Reactome: R-HSA-9634600;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-442720;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-8853659;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-5621575;Reactome: R-HSA-164378;Reactome: R-HSA-392517;Reactome: R-HSA-9010642;Reactome: R-HSA-422356;Reactome: R-HSA-111931;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;Reactome: R-HSA-5610783 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"HDL assembly";"Triglyceride catabolism";"RET signaling";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CD209 (DC-SIGN) signaling";"PKA activation in glucagon signalling";"Rap1 signalling";"ROBO receptors bind AKAP5";"Regulation of insulin secretion";"PKA-mediated phosphorylation of CREB";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"Degradation of GLI2 by the proteasome" XP_008547207.3 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053593185.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014296943.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_008555311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008547083.1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-186797 "Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Integrin cell surface interactions";"NCAM1 interactions";"Signaling by PDGF" XP_053594115.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053597574.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_053595931.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_008549586.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_053598011.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_008548160.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014298331.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008556043.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_008551247.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_008546049.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_008547436.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008558968.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008546783.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014298802.1 17 Reactome: R-HSA-6796648;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1433557 "TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"Signaling by SCF-KIT" XP_008557321.1 2 Reactome: R-HSA-6782861;Reactome: R-HSA-156581 "Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylation" XP_008550865.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_053597959.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_053598243.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053598102.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053594839.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_008557054.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_008546000.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_008555944.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008557385.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_008559427.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014300678.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_008543493.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008546649.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053599228.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_014300577.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_053593962.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008560093.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053597960.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_008544562.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_008551330.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053596895.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_008559605.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_014296794.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_008548619.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008555075.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_053597067.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008545222.2 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014297694.1 13 MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism" XP_008545041.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_008547295.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" NP_001401789.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053598729.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008555402.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_008552097.2 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_053593639.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008549150.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic" XP_008546453.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation" XP_053593489.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_008550630.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008552089.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014299842.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_014295483.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_014296934.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008558564.2 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_053594360.1 6 Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_008546555.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_008553126.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_008550692.1 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_008553123.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_008555124.1 30 Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5684264;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-8854050 "Degradation of GLI2 by the proteasome";"Circadian Clock";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_008560858.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008550030.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_053594202.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_053599088.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053593454.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008544302.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_014294843.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_008558013.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" XP_008555933.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection" NP_001401754.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_053593274.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_053598151.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_008552871.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_008559856.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_014295033.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008550901.1 17 Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616 "Fanconi Anemia Pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_008555379.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008553794.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_008551325.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" NP_001401696.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008554569.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014299719.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-5689877 "Aggrephagy";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs" XP_008544976.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_053593963.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053595964.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_008560615.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_008555336.3 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_008553740.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_008543492.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008547520.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_008557940.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_008550168.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_008547490.1 2 Reactome: R-HSA-3785653;Reactome: R-HSA-3322077 "Myoclonic epilepsy of Lafora";"Glycogen synthesis" XP_053596105.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_053598369.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_014297305.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_053598103.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008552838.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_053597786.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008549624.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_014299225.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053596436.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_014298146.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008560319.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_053593158.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_008556265.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_014296805.1 8 KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_053597604.1 13 MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-6613 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_008548269.1 4 MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_008556858.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_008555746.1 15 Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176407 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_008556042.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_008545510.1 4 Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053594070.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_008551468.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_053594228.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_008555365.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_008561160.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053597217.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008544878.1 4 Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_008554427.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation" XP_053597377.1 6 MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_008557418.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014299834.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_008545105.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_008551029.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008561071.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_053594818.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053594196.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_053596877.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_053599134.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008554958.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692 "Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity" XP_014295032.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008554605.1 14 MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181 "Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Folate transformations I";"Photorespiration " XP_014297636.1 6 MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_008549259.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport" XP_008560155.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008545822.1 6 Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-390247;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-2046106 "Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"alpha-linolenic acid (ALA) metabolism" XP_053594587.1 12 Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1 "G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"mTOR signaling pathway" XP_008560929.3 5 MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7177;Reactome: R-HSA-499943 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates" XP_053593517.1 7 KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22 "Glutathione metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_008543728.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis" XP_014294842.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_008554309.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_008555932.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_008555730.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_008548638.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_053593618.1 6 Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3322077 "Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen synthesis" XP_008553116.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008558387.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008559985.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis" XP_053597316.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008549768.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" XP_014300702.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_008551289.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_014295482.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_053596822.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_008554005.1 4 KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_008560821.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595687.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008549302.1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_008550879.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_008550625.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008560643.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-241 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_053599055.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008555403.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_014300904.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008557936.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008548038.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_053598128.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_008553736.1 9 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_008551540.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_008547000.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_008550365.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008551128.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins" XP_008556689.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_008547345.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014298284.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_053595902.1 19 Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-182971;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-428543;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-4420097 "EPHB-mediated forward signaling";"DCC mediated attractive signaling";"EGFR downregulation";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"Inactivation of CDC42 and RAC1";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway" XP_008549218.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_053598711.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014296954.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-437239 "Resolution of Sister Chromatid Cohesion";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Cilium Assembly";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1" XP_014295653.1 17 KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167200 "T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_008556697.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053595066.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008546208.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008558144.1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476 "Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events" XP_008550669.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724 "Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II" XP_053596308.1 10 Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation" XP_053594973.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_008558383.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_008548771.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648 "Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_008546666.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_008547766.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593355.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_014297499.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_008552319.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism" XP_053593706.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_053599147.1 11 MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_008546083.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_008554199.1 5 Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_014296579.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_008546902.1 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_053595683.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"mTORC1-mediated signalling" XP_008543602.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_008549710.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008547600.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008556654.1 5 Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-936440 "PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling" XP_014299537.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_053595208.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008558800.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008552034.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_008560647.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_008544125.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"mTOR signaling pathway" XP_014296989.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_008559836.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008548354.1 14 MetaCyc: PWY-5101;MetaCyc: PWY-7767;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5104;MetaCyc: PWY-5078;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5057 "L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis IV";"L-isoleucine degradation II";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"L-valine degradation II" XP_053597062.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014295053.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008544674.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_053595666.1 30 Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837 "Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Degradation of GLI2 by the proteasome";"Circadian Clock";"Prolactin receptor signaling";"FCERI mediated NF-kB activation" XP_053597494.1 6 Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700 "RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling" XP_008559840.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014296462.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_053597767.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014300572.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_053596667.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_008557634.1 11 Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268 "Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_053594306.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_053597041.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_053592808.1 6 MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_008559422.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_008555174.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008559592.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_008543324.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008552371.1 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_008550505.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008553694.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014300780.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_053598107.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008545978.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053593814.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008559356.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_008548834.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008550238.1 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324 "Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"NrCAM interactions";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_053595223.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)" XP_008559530.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008552821.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" XP_014299474.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_053598393.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_008559104.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_053598779.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008551242.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008560742.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008554525.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008558713.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_008557034.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014295993.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008555025.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014296694.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_008548281.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I" XP_008553511.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_014294854.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_008546813.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_008554581.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_053597373.1 6 MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560 "Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism" XP_053596699.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014296173.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008554593.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_053595444.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_008544429.1 6 MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898 "Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage III" XP_053594860.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_053596873.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008549146.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_053594154.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism" XP_008551350.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597740.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II" XP_008554722.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_008550631.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_008560545.1 8 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_008550481.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008549151.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport" XP_008544296.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_008550493.1 33 Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408 "EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism" XP_053597177.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway" XP_008554716.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053594038.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008544128.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_008543769.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_053595637.1 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis" XP_008560987.2 4 KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine" XP_008556526.1 10 Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-6798695;MetaCyc: PWY-5691 "Amyloid fiber formation";"Purine metabolism";"Retinoid metabolism and transport";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Neutrophil degranulation";"Urate conversion to allantoin I" XP_014298721.2 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_053595487.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233 "PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway" XP_014295682.1 15 Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-179409 "Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A" XP_008549079.1 1 MetaCyc: PWY-6938 "NADH repair" XP_008551851.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription" XP_014299339.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_008555603.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_053599019.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5685939 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" XP_008558412.1 12 Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-2122948 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_053594361.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_008558240.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling" XP_053596009.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008545127.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-350054 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway" XP_053595037.1 24 Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-5625740;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05163+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-2730905 "CLEC7A (Dectin-1) signaling";"mTOR signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"RSK activation";"RHO GTPases activate PKNs";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Human cytomegalovirus infection";"Downstream TCR signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization" XP_008552018.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_053593358.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_014297105.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008556388.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_008546538.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014296786.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_008550031.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008549215.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_014299614.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_008553827.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_008548688.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_014296763.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5578775 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis" XP_053594847.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_053595652.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" NP_001401718.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008550368.1 57 Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-69017 "Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6" XP_008545009.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008547997.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008545756.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008555003.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_008553004.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_014294972.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008545948.3 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053593838.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_008555270.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_008555469.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_014298392.1 7 KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism" XP_053595001.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_008550214.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_008549611.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008548196.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_008554140.1 12 KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-383280;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"p38MAPK events";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Nuclear Receptor transcription pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_014296322.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_008555028.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014298330.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597116.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_008545565.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008556718.1 14 Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-6607;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;Reactome: R-HSA-8851680;MetaCyc: PWY-5695;KEGG: 00232+1.17.3.2 "Purine catabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Guanosine nucleotides degradation I";"Drug metabolism - other enzymes";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation";"Caffeine metabolism" XP_008548161.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_053596036.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_053592942.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053598010.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_008554528.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_053595930.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_014300168.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014297198.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008558301.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_053597996.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014299231.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008553316.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008544846.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008557320.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_053594269.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_053595601.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008550508.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008551331.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008559382.2 6 MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13 "L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_053596565.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_053596636.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053593936.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_053596486.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_008549424.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_053598976.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_053592805.1 6 KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" XP_008560513.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_008547482.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_008557018.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_008554027.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008560355.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER" XP_008546930.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_008544350.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_008543630.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_053598429.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_008556006.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_008547653.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_008555900.1 13 MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384 "Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_008559022.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_008545467.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_008550780.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66 "3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_053593789.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_053597441.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008557084.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_008545108.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" XP_053594225.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_053598945.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008551465.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_053596943.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_008544779.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008551586.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_053596499.1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_053596529.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_014299670.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_008553808.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_008556962.1 6 Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport" XP_008556760.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_008556855.1 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_008555031.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_008549247.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_053593754.1 30 Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-2564830;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-73762 "Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase I Transcription Initiation" XP_008550603.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_008556268.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" XP_014296808.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_008556784.1 13 MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736 "Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis" XP_008559970.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_008548189.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_053594834.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_008550165.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_008547744.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_008545499.1 5 Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_053598206.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_008546644.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_008545943.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_014299161.1 14 MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6538;MetaCyc: PWY-6999;MetaCyc: PWY-6607;Reactome: R-HSA-8851680;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-5695;KEGG: 00232+1.17.3.2 "Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Theophylline degradation";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Drug metabolism - other enzymes";"Purine metabolism";"Inosine 5'-phosphate degradation";"Caffeine metabolism" XP_053594139.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014297401.2 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_008550288.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_008551328.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053596123.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008556039.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_053594021.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597173.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_008550497.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" XP_053595975.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_008547400.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_053598674.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170660 "G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase activating pathway" XP_053595633.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_008550628.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_053595483.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053595491.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847 "Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones" XP_008555607.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_008559077.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014299587.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014298729.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_008557224.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_053598181.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695 "Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_008555508.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253 "A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_053595466.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014298881.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_053596794.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_008559282.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008558597.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008545123.1 6 KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;Reactome: R-HSA-73817 "Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis" XP_008544711.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_053596915.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_008558979.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_053593459.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_014300689.2 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_014298234.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_008550450.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_008548635.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008557739.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008543675.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_014295273.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008543725.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008546975.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" XP_014295907.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Purine metabolism" XP_053593279.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_053594843.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_014297667.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-141430 "APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_008561147.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_053593460.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_053597094.1 11 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_014299088.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_008560986.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_008550310.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_053598239.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_008552684.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008555007.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_008557999.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008545794.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008547449.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_008555374.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_008556335.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;MetaCyc: PWY-7511 "TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"Protein ubiquitination" XP_053594106.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008558333.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_008555214.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_008547205.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_014298846.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_053593858.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_053595969.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_053597040.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_053598803.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_008560454.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014300675.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_008545942.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-5632684 "G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state" XP_008543069.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_008559841.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008547538.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_053598364.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_008549393.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008559531.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008546997.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014300829.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008549779.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_008550868.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_053596709.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_053594998.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_008553086.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_053597609.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation" XP_008548788.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008548280.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_008556963.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-416993 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors" XP_008550255.1 8 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_053592947.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_008549107.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008560489.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014296327.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_053593956.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053593188.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008551351.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014298065.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_008555080.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_008543365.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_008556887.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008553436.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-69601 "Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_053594861.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014298397.1 1 Reactome: R-HSA-6803529 "FGFR2 alternative splicing" XP_008559023.1 18 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Ether lipid metabolism" XP_008545709.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_008545178.3 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_053599139.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008549029.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008550991.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_053595348.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008560335.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport" XP_008549131.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling" XP_014294977.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008553440.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008543792.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008551259.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008554863.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_008557210.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008560759.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008546057.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053594246.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008557370.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_053594590.1 12 Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840 "DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Rho GTPase cycle" XP_014299655.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_053594842.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768 "Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_008547001.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053594058.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation" XP_008553198.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053596996.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053595090.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_008551541.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_053595176.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_008552388.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008547732.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008555728.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257 "MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion" XP_014295326.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008555678.1 13 Reactome: R-HSA-110320;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695 "Translesion Synthesis by POLH";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"HSF1 activation";"ABC-family proteins mediated transport";"Protein methylation";"Neutrophil degranulation" XP_014295087.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_008551260.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"MAP2K and MAPK activation" XP_008560962.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014298509.1 5 Reactome: R-HSA-3299685;Reactome: R-HSA-1236973;Reactome: R-HSA-4420097;Reactome: R-HSA-5668599;Reactome: R-HSA-1222556 "Detoxification of Reactive Oxygen Species";"Cross-presentation of particulate exogenous antigens (phagosomes)";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate NADPH Oxidases";"ROS and RNS production in phagocytes" XP_008551479.1 8 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_053595032.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008555577.1 8 MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_053598710.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_008547601.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_053595057.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_008543505.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway" XP_008551768.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" XP_008559283.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_053598378.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_008558417.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_053595690.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_053598828.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008555220.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_053594557.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_014299055.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_014295687.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_053595632.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_008559507.1 13 Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948 "Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"Human papillomavirus infection";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants" XP_014295067.2 5 MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II" XP_014295588.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008550179.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_053593747.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_008560121.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_053596122.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_008558801.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053596898.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008544234.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_014296227.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008555002.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_014295066.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008552335.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008545989.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_053599038.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_008549128.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053595653.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_053593654.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008551763.3 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008548202.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_008543956.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053598768.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_008544079.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_008550664.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008554914.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8953750 "HCMV Early Events";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6" XP_008548806.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_053594019.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008544825.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_008558413.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_053593054.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_008554194.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_008560210.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_008557006.1 52 Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210 "Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_008546653.1 9 MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle" XP_053593439.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_008555868.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_008559072.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_053594553.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008560442.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053596441.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008559503.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_053594619.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_008547044.1 18 MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7221 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis" XP_008544893.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_008548359.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_008550492.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_008547483.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008546925.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_053594721.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_053598807.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008543775.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_008547521.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_008548549.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_008553741.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_008543174.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662 "Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism" XP_008545173.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_008559383.2 6 Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)" XP_008544611.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_008550078.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_008560526.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_053593715.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_053594889.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008560512.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_008546449.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008543681.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_008554551.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_008543693.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_008545694.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_008549397.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_008546993.1 5 MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis" XP_008555324.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142 "Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"SUMOylation of ubiquitinylation proteins" XP_008547585.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_014294884.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008548839.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_008551380.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053594184.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_008550220.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_008556835.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_053596462.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_008559528.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_053592943.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053595733.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_053593734.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_053595925.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_008559363.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_008556967.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008548504.2 3 Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45 "Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism" XP_008558294.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014296323.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_008554200.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4570464 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins" XP_053594854.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008557039.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_053598175.1 14 MetaCyc: PWY-5104;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42 "L-isoleucine biosynthesis IV";"L-valine degradation II";"L-leucine degradation III";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation" XP_008552006.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)" XP_014300750.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_053595449.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I" XP_008556814.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014298779.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_014296741.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_014297939.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014297641.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_008555707.1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_014298393.1 7 KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism" XP_008544083.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058 "Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_008558824.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008559940.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014297281.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_008558374.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" XP_008555589.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" XP_008544700.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_053595851.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014300882.1 4 KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937 "Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation";"Iron uptake and transport" XP_008560809.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_053598033.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008546125.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_053595074.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053593073.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_008550857.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_008545973.1 10 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" XP_014298273.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_014295234.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_014300137.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_008547624.1 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway" XP_008550301.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5871 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_014297544.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_053597839.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_053593194.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008560840.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_008544845.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_008553315.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008554871.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_008554321.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008544433.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_053593795.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_008554439.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_053596421.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_053597995.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_008556919.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008546074.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_008545035.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008546913.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014296334.1 13 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation" XP_008554743.1 16 Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones" XP_053596635.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008549082.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_053592806.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_053595674.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008560530.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_053596973.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_053599004.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_053598975.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008546945.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_014296159.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_008556525.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" XP_053597359.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_008556495.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_008558493.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5 "TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism" XP_008543645.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_008557575.1 4 KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I";"Formation of xylulose-5-phosphate" XP_014297536.2 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_008557253.1 13 MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism" XP_053595668.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_008553889.1 6 Reactome: R-HSA-2426168;Reactome: R-HSA-446199;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273 "Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_014300387.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014300841.2 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_053597655.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_053593708.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_053596860.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6 "Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism" XP_008553785.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_008556581.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_008556593.1 8 Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6664;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661 "Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_008559120.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008547479.1 30 Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783 "GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Circadian Clock";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome" XP_008544813.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_008555183.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_008548205.2 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_008560232.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008550240.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_008547831.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053594873.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008550596.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014300367.2 6 MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22 "Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism" XP_008550748.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_008559796.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008557162.1 44 Reactome: R-HSA-5663213;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5675221;Reactome: R-HSA-5668599;Reactome: R-HSA-8939211;Reactome: R-HSA-8943724;Reactome: R-HSA-6811558;Reactome: R-HSA-2559582;Reactome: R-HSA-5654733;Reactome: R-HSA-74749;Reactome: R-HSA-450341;Reactome: R-HSA-375165;Reactome: R-HSA-8940973;Reactome: R-HSA-198753;Reactome: R-HSA-2871796;Reactome: R-HSA-5674499;Reactome: R-HSA-2029482;Reactome: R-HSA-881907;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-202670;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-9635465;Reactome: R-HSA-456926;Reactome: R-HSA-9627069;Reactome: R-HSA-9634638;Reactome: R-HSA-445144;Reactome: R-HSA-5654727;Reactome: R-HSA-6802952;Reactome: R-HSA-444257;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-3371453;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-162658;Reactome: R-HSA-170968;Reactome: R-HSA-6802946 "RHO GTPases Activate WASPs and WAVEs";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"Negative regulation of MAPK pathway";"RHO GTPases Activate NADPH Oxidases";"ESR-mediated signaling";"Regulation of PTEN gene transcription";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR4 signaling";"Signal attenuation";"Activation of the AP-1 family of transcription factors";"NCAM signaling for neurite out-growth";"RUNX2 regulates osteoblast differentiation";"ERK/MAPK targets";"FCERI mediated MAPK activation";"Negative feedback regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Gastrin-CREB signalling pathway via PKC and MAPK";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ERKs are inactivated";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Suppression of apoptosis";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of the apoptosome activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signal transduction by L1";"Negative regulation of FGFR2 signaling";"Signaling by BRAF and RAF fusions";"RSK activation";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Regulation of HSF1-mediated heat shock response";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Frs2-mediated activation";"Signaling by moderate kinase activity BRAF mutants" XP_053592923.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_008550593.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053597384.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053595945.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_053597143.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008553854.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_008547284.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580 "Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence" XP_053594568.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008547768.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014296785.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008545859.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008553071.1 10 Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537;MetaCyc: PWY-4321;MetaCyc: PWY-5022 "Degradation of GABA";"beta-Alanine metabolism";"Propanoate metabolism";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"4-aminobutanoate degradation V" XP_014297106.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008545755.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008554932.2 57 Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050 "Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_014299483.2 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_008558702.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008551126.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_008549791.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_008547130.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008559789.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids" XP_014298812.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008548947.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014297361.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761 "TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling" XP_008546010.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014300745.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433 "Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)" XP_008545720.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014300539.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008555542.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008543076.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual incision in TC-NER" XP_008548398.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_053598112.1 5 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_053595465.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_008556427.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008552840.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014294942.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_008544817.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408 "HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism" XP_008546878.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER" XP_053597318.1 12 Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001 "Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"NrCAM interactions";"Trafficking of AMPA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade" XP_008557477.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_053594877.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008547378.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_008555187.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008552809.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008558028.1 13 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation" XP_008543726.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008549600.1 13 Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-5689877;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346 "Defective CFTR causes cystic fibrosis";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"Josephin domain DUBs";"Neutrophil degranulation";"Protein methylation";"ABC-family proteins mediated transport";"HSF1 activation";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis" XP_008543676.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_008550979.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_053596670.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014299529.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434 "Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Kinesins";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Cilium Assembly";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008558450.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_053593970.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_053597147.1 31 MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-6519;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-7858;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799 "Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)" XP_053598732.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053595010.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_008561094.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_008545161.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_053593616.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_053598001.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008554301.3 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_014297638.1 6 MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_008545851.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014296738.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_008556336.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN" XP_008556550.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_008547504.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_008544980.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_053598992.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008544782.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128 "Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling" XP_008553420.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593863.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_008544087.1 7 MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_053594822.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008556005.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008558003.1 10 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357905 "Human papillomavirus infection";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TNFR1 signaling" XP_053596088.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008551633.1 7 MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659 "Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis" XP_014295164.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_014297297.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_008552477.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_008551483.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)" XP_053593077.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008543382.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_053593304.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008547380.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_008552938.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008556856.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_008548127.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_008555748.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_008551585.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014296658.1 9 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_014298903.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_008545203.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008546880.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008545142.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700 "FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling" XP_053596438.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_014298148.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053596688.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_008546864.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910 "SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs" XP_053595197.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008544588.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008559615.1 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_014298490.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008544437.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014300072.2 5 Reactome: R-HSA-8963896;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "HDL assembly";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_008543617.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_008549273.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053592972.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes" XP_008544699.2 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_008559319.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" NP_001401698.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_053595880.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_008550166.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_053593677.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014296420.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_008547803.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053598449.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_008554371.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_008544783.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897 "Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes" XP_053596995.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-432040 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_053598981.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008549964.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy" XP_008557233.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014295393.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_053595624.1 17 KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-6722;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-200425;Reactome: R-HSA-3371599;MetaCyc: PWY-5743 "Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Glyoxylate assimilation";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Carnitine metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle" XP_008557408.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_053595774.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_053596923.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008546807.1 13 Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757 "Macroautophagy";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation" XP_008544931.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_053597207.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Relaxin signaling pathway" XP_008560252.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_053595175.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_008560191.2 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_053592884.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008549227.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_008546024.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_008544600.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-8939902 "Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity" XP_008560605.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972 "Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)" XP_008548694.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008561172.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008543506.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_008558051.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_008553128.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008554155.1 13 KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3 "Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate polyglutamylation";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Folate transformations I";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes" XP_008551997.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008555543.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014296225.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_014297315.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053593023.1 42 Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-110331;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-3214841;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-110329 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged purine";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"Meiotic recombination";"PKMTs methylate histone lysines";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine" XP_053597614.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF activation";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation" XP_053597035.1 7 KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" XP_008550357.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000 "Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RAF activation" XP_014296815.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_008545828.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_053596714.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008551701.1 4 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_014300712.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_008555515.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_053599212.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_053597306.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523 "Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008550547.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053594041.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014300676.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_008554484.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_053598744.1 24 Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-418597 "Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events" XP_014298845.1 17 Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_053596806.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_008547567.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_014296389.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_053597189.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008555413.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110314 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex" XP_008553085.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_008561040.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785 "Hedgehog 'off' state";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome" XP_008556253.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_008551057.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_053598519.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism" XP_053593291.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-977225 "Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy";"Amyloid fiber formation" XP_008545143.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_008556921.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008545384.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_008543383.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_008546541.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008545806.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_008553533.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_053593266.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053596360.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_008560098.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_008554319.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_053594823.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014297160.1 8 Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_014294934.1 6 MetaCyc: PWY-7765;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7717 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I" XP_014296354.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_008551482.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_053598653.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_053593955.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_053593862.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_008553435.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_014298514.1 5 Reactome: R-HSA-1236973;Reactome: R-HSA-3299685;Reactome: R-HSA-4420097;Reactome: R-HSA-1222556;Reactome: R-HSA-5668599 "Cross-presentation of particulate exogenous antigens (phagosomes)";"Detoxification of Reactive Oxygen Species";"VEGFA-VEGFR2 Pathway";"ROS and RNS production in phagocytes";"RHO GTPases Activate NADPH Oxidases" XP_014296021.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_053593716.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_008560525.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008549083.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_053596620.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_053596972.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_014298687.1 25 Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-381771;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-400042 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"G-protein activation";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion" XP_053594763.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_008547563.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008558078.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_008544148.1 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" XP_008559654.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_008551653.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events" XP_053598690.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_008549066.1 11 KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8866654 "mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008544432.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_008552237.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_008558810.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2 "Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_014300153.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_014295540.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008547586.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_008547465.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_053595828.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation" XP_053593287.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008545620.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053593136.1 24 Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434 "Gap junction assembly";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Cilium Assembly";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008561195.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_008553488.1 10 KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis" XP_053598176.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_053593405.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_008556938.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_053595710.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014297861.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008552252.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_008548122.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_053598032.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_008560426.2 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_053593072.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_053595926.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008559321.1 9 Reactome: R-HSA-9608290;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9608287;Reactome: R-HSA-110331 "Defective MUTYH substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate binding";"Cleavage of the damaged purine" XP_008555332.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_014296038.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_008544277.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" XP_008546378.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_053598701.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008544903.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053594827.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_053594377.1 30 Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-68949;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546 "Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Degradation of GLI2 by the proteasome";"Circadian Clock";"FCERI mediated NF-kB activation";"Prolactin receptor signaling" XP_008558987.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_008552005.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014300866.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_053598997.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014295435.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008552069.3 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_053597438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053598348.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_008553501.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_008548056.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_014295397.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858 "Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity" XP_053596788.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_053597142.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_053598737.1 31 MetaCyc: PWY-8012;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-7723;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-8047;MetaCyc: PWY-5971;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-7858 "Mupirocin biosynthesis";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Bryostatin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II" XP_008554120.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_008556809.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_008555048.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008555965.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_008548805.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_053596927.1 16 MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4 "Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Citrate cycle (TCA cycle)" XP_008552569.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_008557309.1 1 Reactome: R-HSA-419771 "Opsins" XP_008547917.1 16 MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_008546146.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_008550534.1 57 Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276 "Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_053593528.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593498.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_014295350.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947 "NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription" XP_008551733.1 5 Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling" XP_008560233.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_008544222.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_053594872.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014300584.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_008544826.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_053598950.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008544812.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_053596280.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014298817.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_008548177.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_008557856.1 8 KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817 "T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_008552683.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008545793.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008553374.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008560227.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation" XP_008555799.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_014298167.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_008549252.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_008548970.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_053595279.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_053594844.1 5 Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_053597093.1 11 Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_053595319.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_008546484.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;MetaCyc: PWY-5723 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt" XP_008544162.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053596402.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008545675.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014294849.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_008558019.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_008552535.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_008555939.1 5 MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863 "Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis" XP_014296718.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_008549005.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008560964.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008555895.1 9 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER" XP_014296751.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_053597025.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_008553508.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_053598341.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_008547819.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097 "Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway" XP_053598795.1 42 Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222 "SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Meiotic recombination";"HDMs demethylate histones";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"DNA methylation";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic synapsis";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transcriptional regulation of granulopoiesis" XP_008560980.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_053596793.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_014298894.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_014296129.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692 "NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity" XP_008552091.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008554831.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807 "Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling" XP_008546460.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_008558315.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" XP_008550872.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053598723.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" NP_001401783.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008554541.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_014299382.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_008555767.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949 "Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin" XP_053595634.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_053597775.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165 "Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)" XP_008546459.1 23 Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-420092 "Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Glucagon-type ligand receptors" XP_053598935.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_053597625.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_053595484.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_053596933.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_008557295.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_008549186.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008550456.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008546034.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_014296214.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_008550763.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_008548891.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053597407.1 3 Reactome: R-HSA-5173214;Reactome: R-HSA-189085;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014296368.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_008547743.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation" XP_008556766.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008556931.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_008553481.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system" XP_008543943.1 19 Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;Reactome: R-HSA-75105;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-7384;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5 "ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism" XP_008560326.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_053598362.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_008546821.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_008551772.1 7 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression" XP_008550786.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_008551616.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053596311.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483 "AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs" XP_053593753.1 30 Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-2564830;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167152 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat" XP_008547321.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_008548349.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_008556783.1 13 MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736 "Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis" XP_008558071.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_014295268.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014295185.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_008558160.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_008545451.1 20 Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397 "Processing of DNA double-strand break ends";"Dual incision in TC-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_014299076.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008548300.1 7 KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014299887.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_008560978.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008557083.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_053592879.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008548153.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008560437.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008560687.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_008553900.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014299673.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008554147.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008553778.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5668541 "Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway" XP_008556928.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_053597403.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_008547061.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014300579.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_053597110.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_008545630.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053596030.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_008543172.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_053598016.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_008547170.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339 "Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane" XP_053595761.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_008559599.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_008547747.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142 "SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins" XP_008547096.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_053594837.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014295718.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_008557588.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_008551200.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_008552980.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_053597238.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_053593757.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_053596630.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_008550939.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014298597.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_053593732.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_053598772.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_008560749.1 5 Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-209560 "Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NF-kB is activated and signals survival" XP_008547081.2 3 MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis" XP_014299891.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism" XP_053594965.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008548910.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_053594048.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_008548157.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_008560433.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" XP_008550213.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_053598580.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008557087.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_014296527.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_008556812.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_008553498.3 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_008553310.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008557272.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014296778.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053597365.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis" XP_014298163.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400 "WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Degradation of DVL";"PCP/CE pathway" XP_008558058.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_014299241.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008555004.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053595418.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008545797.1 8 KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_008552437.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_008547188.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_008556432.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014297664.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_008547265.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_014300694.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_008560409.2 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_053593652.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014299559.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_053597746.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_008548204.1 11 KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-2029485;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453 "Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Stigma estolide biosynthesis" XP_008556148.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_008544290.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_053598282.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014299560.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_014299613.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_008550662.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_053596646.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_008545258.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008543127.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_053595358.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053594390.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation" XP_008557570.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014295388.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_008556082.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_008555786.1 10 Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_014297522.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014297434.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_008552326.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008552312.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_053597697.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008554192.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_008556317.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053596478.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053597428.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008556277.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_008545865.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_008559074.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_008556903.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_053598156.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_053597598.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_008557964.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_053593487.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008551502.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" NP_001401787.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_008556457.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008554130.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_053593205.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_008551910.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_014299974.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_008549233.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_053596046.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_053596879.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_008547319.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_053598841.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_008557313.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_053597829.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201 "Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_008547279.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008554429.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation" XP_008550212.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_014294968.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_053598695.1 7 MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-4302;MetaCyc: PWY-3781;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-6692 "NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Complex I biogenesis";"Fe(II) oxidation" XP_053596681.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_053597781.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_008558815.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_053596329.1 4 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_014299882.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_014296324.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_053594911.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_053595406.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430 "G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation" XP_008548299.1 7 Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"UTP and CTP de novo biosynthesis" XP_014297824.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_053597725.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_014300305.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_008549104.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_008560490.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053593733.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_008546114.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_008548267.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism" XP_053596081.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482 "Myogenesis";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation" XP_053594183.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053598367.1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_008560903.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020 "Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import" XP_008543694.1 6 Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "Galactose catabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" XP_008555323.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_053595715.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053596025.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008545625.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_008547484.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008552649.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014296707.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_008552766.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_053597402.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014299608.2 17 Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174178 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_008546734.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_008553111.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008549232.1 7 Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632 "Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Meiotic synapsis" XP_053592933.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008558354.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008556066.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_014300636.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_014296991.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014300565.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_014299773.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_053595689.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014296447.2 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_008546654.1 9 MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_008559710.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008555959.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_053595321.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_008556902.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_053594554.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014295060.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_014297481.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014297631.1 6 MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_008547155.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_053593053.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_008554193.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_008544408.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078 "Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" XP_008548539.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_053597451.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_008557649.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_008556749.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_008546385.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_014300036.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_008548144.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014296602.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_014295659.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471 "Downstream signal transduction";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_008549798.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" XP_014296868.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_014299612.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_008550663.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008550510.1 16 Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347 "Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling" XP_008554851.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053596407.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_053598608.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053594589.1 12 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"mTOR signaling pathway";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection" XP_008557345.1 5 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097 "p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway" XP_008548366.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_008560826.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_008558435.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014297461.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008553475.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_008558106.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_053593653.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008546054.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_008544233.1 182 Reactome: R-HSA-1236382;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-2122948;Reactome: R-HSA-174113;Reactome: R-HSA-1169408;Reactome: R-HSA-8951664;Reactome: R-HSA-5654733;Reactome: R-HSA-936440;Reactome: R-HSA-5607764;Reactome: R-HSA-209560;Reactome: R-HSA-174048;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5357956;Reactome: R-HSA-2122947;Reactome: R-HSA-168927;Reactome: R-HSA-5362768;Reactome: R-HSA-2559580;Reactome: R-HSA-6782135;Reactome: R-HSA-72649;Reactome: R-HSA-2691232;Reactome: R-HSA-8948747;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-6783310;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8875360;Reactome: R-HSA-9646399;Reactome: R-HSA-5685942;Reactome: R-HSA-68949;Reactome: R-HSA-936964;Reactome: R-HSA-2408557;Reactome: R-HSA-2672351;Reactome: R-HSA-8866652;Reactome: R-HSA-2644606;Reactome: R-HSA-912631;Reactome: R-HSA-5693607;Reactome: R-HSA-937072;Reactome: R-HSA-72689;Reactome: R-HSA-8863795;Reactome: R-HSA-450408;Reactome: R-HSA-205043;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-5696400;Reactome: R-HSA-9033241;Reactome: R-HSA-5696397;Reactome: R-HSA-5658442;Reactome: R-HSA-168928;Reactome: R-HSA-209543;Reactome: R-HSA-69601;Reactome: R-HSA-72702;Reactome: R-HSA-2559585;Reactome: R-HSA-8941858;Reactome: R-HSA-975957;Reactome: R-HSA-5655862;Reactome: R-HSA-187577;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5654732;Reactome: R-HSA-72764;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-975144;Reactome: R-HSA-5654726;Reactome: R-HSA-3769402;Reactome: R-HSA-5689877;Reactome: R-HSA-156827;Reactome: R-HSA-110314;Reactome: R-HSA-977225;Reactome: R-HSA-9613829;Reactome: R-HSA-5689896;Reactome: R-HSA-5696394;Reactome: R-HSA-3785653;Reactome: R-HSA-168638;Reactome: R-HSA-9633012;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-110320;Reactome: R-HSA-937042;Reactome: R-HSA-532668;Reactome: R-HSA-8856828;Reactome: R-HSA-8866654;Reactome: R-HSA-9013973;Reactome: R-HSA-72706;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-6804757;Reactome: R-HSA-975110;Reactome: R-HSA-2173791;Reactome: R-HSA-5632684;Reactome: R-HSA-72695;Reactome: R-HSA-9645460;Reactome: R-HSA-9637628;Reactome: R-HSA-5689901;Reactome: R-HSA-110312;Reactome: R-HSA-5684264;Reactome: R-HSA-2559582;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-2979096;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-162588;Reactome: R-HSA-5675221;Reactome: R-HSA-937041;Reactome: R-HSA-6807004;Reactome: R-HSA-9013507;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8876493;Reactome: R-HSA-8948751;Reactome: R-HSA-3134975;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339;Reactome: R-HSA-1295596;Reactome: R-HSA-182971;Reactome: R-HSA-3322077;Reactome: R-HSA-2173796;Reactome: R-HSA-400253;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-174490;Reactome: R-HSA-6804756;Reactome: R-HSA-937039;Reactome: R-HSA-9636383;Reactome: R-HSA-2565942;Reactome: R-HSA-917729;Reactome: R-HSA-5357905;Reactome: R-HSA-975956;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-69541;Reactome: R-HSA-192823;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-6782210;Reactome: R-HSA-6804760;Reactome: R-HSA-2173795;Reactome: R-HSA-9014325;Reactome: R-HSA-175474;Reactome: R-HSA-5607761;Reactome: R-HSA-1253288;Reactome: R-HSA-9615710;Reactome: R-HSA-5675482;Reactome: R-HSA-5656169;Reactome: R-HSA-2173788;Reactome: R-HSA-68827;Reactome: R-HSA-901032;Reactome: R-HSA-5693565;Reactome: R-HSA-6781823;Reactome: R-HSA-8849469;Reactome: R-HSA-975163;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-5610783;Reactome: R-HSA-6791226;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-450321;Reactome: R-HSA-5656121;Reactome: R-HSA-156902;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641263 "Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"ISG15 antiviral mechanism";"Neddylation";"Negative regulation of FGFR4 signaling";"Negative regulators of DDX58/IFIH1 signaling";"CLEC7A (Dectin-1) signaling";"NF-kB is activated and signals survival";"APC/C:Cdc20 mediated degradation of Cyclin B";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"TNFR1-induced NFkappaB signaling pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"TICAM1, RIP1-mediated IKK complex recruitment";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxidative Stress Induced Senescence";"Dual incision in TC-NER";"Translation initiation complex formation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of PTEN localization";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Fanconi Anemia Pathway";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"InlB-mediated entry of Listeria monocytogenes into host cell";"Aggrephagy";"HDR through Homologous Recombination (HRR)";"Orc1 removal from chromatin";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Selenocysteine synthesis";"Stimuli-sensing channels";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of signaling by CBL";"Processing of DNA double-strand break ends";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Formation of a pool of free 40S subunits";"Downregulation of ERBB2 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NRIF signals cell death from the nucleus";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"UCH proteinases";"Dual Incision in GG-NER";"Peroxisomal protein import";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of RAS by GAPs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"p75NTR recruits signalling complexes";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ribosomal scanning and start codon recognition";"Oncogene Induced Senescence";"Regulation of RUNX3 expression and activity";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translesion synthesis by POLK";"SCF(Skp2)-mediated degradation of p27/p21";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Negative regulation of FGFR3 signaling";"Eukaryotic Translation Termination";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR1 signaling";"Deactivation of the beta-catenin transactivating complex";"Josephin domain DUBs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recognition of DNA damage by PCNA-containing replication complex";"Amyloid fiber formation";"Chaperone Mediated Autophagy";"Ovarian tumor domain proteases";"DNA Damage Recognition in GG-NER";"Myoclonic epilepsy of Lafora";"NOD1/2 Signaling Pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Translesion Synthesis by POLH";"IRAK2 mediated activation of TAK1 complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Clathrin-mediated endocytosis";"E3 ubiquitin ligases ubiquitinate target proteins";"TICAM1-dependent activation of IRF3/IRF7";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Degradation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Hedgehog 'on' state";"Formation of the ternary complex, and subsequently, the 43S complex";"Alpha-protein kinase 1 signaling pathway";"Modulation by Mtb of host immune system";"Metalloprotease DUBs";"Translesion synthesis by REV1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Senescence-Associated Secretory Phenotype (SASP)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"Budding and maturation of HIV virion";"Negative regulation of MAPK pathway";"IKK complex recruitment mediated by RIP1";"Negative regulation of MET activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of PTEN stability and activity";"Regulation of innate immune responses to cytosolic DNA";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Spry regulation of FGF signaling";"EGFR downregulation";"Glycogen synthesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Circadian Clock";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Membrane binding and targetting of GAG proteins";"Regulation of TP53 Activity through Phosphorylation";"IRAK1 recruits IKK complex";"Prevention of phagosomal-lysosomal fusion";"Regulation of PLK1 Activity at G2/M Transition";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TNFR1 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Stabilization of p53";"Viral mRNA Translation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Methylation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Assembly Of The HIV Virion";"Dectin-1 mediated noncanonical NF-kB signaling";"Downregulation of ERBB4 signaling";"Late endosomal microautophagy";"Regulation of necroptotic cell death";"Termination of translesion DNA synthesis";"Downregulation of TGF-beta receptor signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER Quality Control Compartment (ERQC)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of TC-NER Pre-Incision Complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Degradation of GLI2 by the proteasome";"Major pathway of rRNA processing in the nucleolus and cytosol";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by POLI";"Peptide chain elongation";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Regulation of FZD by ubiquitination" XP_008547821.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_053598507.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_053597271.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008549257.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_008546871.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_008554239.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_053598266.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_008557788.3 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" XP_008555918.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_008546661.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_014298798.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_008558396.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008548776.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_008554880.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_053598722.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_008556452.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_008560766.1 7 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_008543404.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_014300652.2 6 Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_008550395.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_053596932.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism" XP_008553446.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation" XP_008543897.3 1 Reactome: R-HSA-8876725 "Protein methylation" XP_053594412.1 3 KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" XP_008558361.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_008553810.1 52 Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-113418;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-203927;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210 "Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_008554197.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_008545505.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008560791.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_008551283.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_053596792.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_008559284.1 6 MetaCyc: PWY-7980;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Mitochondrial protein import";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis" XP_053597030.1 15 MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism" XP_053595661.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling" XP_014298836.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_008552490.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_053598405.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053596403.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_008556978.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_053596238.1 7 Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82 "Synthesis of PC";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism" XP_008555198.1 6 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation" XP_053597092.1 11 Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_008547838.1 8 KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1 "Purine metabolism";"Adenine and adenosine salvage III";"Purine salvage";"Surfactant metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II" XP_014300205.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_008555822.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_008554150.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_053593090.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008559259.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_008546096.1 7 MetaCyc: PWY-6352;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11 "3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_014298290.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_053592865.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_053596505.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_008549253.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_008544186.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_008545097.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_008552826.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_053597478.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_008559024.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II" XP_008550984.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008558758.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_008557277.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_053593348.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008558501.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_008552812.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008557082.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_014296684.2 15 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_008544427.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-7356;Reactome: R-HSA-196819 "Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism" XP_008556817.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008543248.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008545365.1 5 MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation" XP_014298840.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_053598498.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008548717.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_008551095.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008555510.1 29 Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-6782135 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER" XP_053598777.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014298416.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008557457.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_008555083.2 5 Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781 "Phase I - Functionalization of compounds";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression" XP_008545669.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_008557432.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_053596650.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_014298809.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_008555877.1 22 KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6142;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;MetaCyc: PWY-5384;MetaCyc: PWY-5514;Reactome: R-HSA-70263;MetaCyc: PWY-7347;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-621;MetaCyc: PWY-622;MetaCyc: PWY-3801;MetaCyc: PWY-6992;MetaCyc: PWY-6981;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-8013 "Pentose phosphate pathway";"Starch and sucrose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Glycolysis";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Gluconeogenesis";"Sucrose biosynthesis III";"Glycolysis / Gluconeogenesis";"GDP-mannose biosynthesis";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Starch biosynthesis";"Sucrose degradation II (sucrose synthase)";"1,5-anhydrofructose degradation";"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_053596097.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_053598363.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_008544098.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_008560907.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling" XP_008555327.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_014294887.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_008545050.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_053594832.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_008554465.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_008547940.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_008553492.1 7 Reactome: R-HSA-983168;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3108214 "Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins" XP_008546642.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_008550308.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014299299.1 13 MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_008550960.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_053596669.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008554563.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-1236382;Reactome: R-HSA-8863795;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-9665233;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-9665245;Reactome: R-HSA-9665247 "Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to osimertinib" XP_008557148.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053595042.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_008554976.1 6 MetaCyc: PWY-622;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_053594890.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008551695.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;Reactome: R-HSA-1483166;MetaCyc: PWY-5269 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Synthesis of PG";"Cardiolipin biosynthesis I";"Synthesis of PA";"Cardiolipin biosynthesis II" XP_053598804.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_053595677.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014295340.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_053596017.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008550671.1 7 MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-5941 "Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Neutrophil degranulation";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen degradation II" XP_008545617.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008554482.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008560629.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_053598940.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_008551319.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_008551459.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_008557410.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014296748.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_008543088.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" XP_008550184.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_008555905.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_014299219.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053599129.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_008549039.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008544320.1 4 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_008546863.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_008548258.1 29 Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape" XP_008544618.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_008559585.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008546727.1 33 Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-141444 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_008545204.1 11 Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-1268020 "Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Mitochondrial protein import" XP_053595886.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_053597717.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_053594728.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_053593169.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-112043 "FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"PLC beta mediated events" XP_014296596.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_053598358.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_008558377.1 3 Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation" XP_053594987.1 4 KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_008549639.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_008543587.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842 "Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification II" XP_008552830.1 18 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_008551634.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_014296352.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_053593864.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014297048.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_014298512.1 5 Reactome: R-HSA-3299685;Reactome: R-HSA-1236973;Reactome: R-HSA-1222556;Reactome: R-HSA-5668599;Reactome: R-HSA-4420097 "Detoxification of Reactive Oxygen Species";"Cross-presentation of particulate exogenous antigens (phagosomes)";"ROS and RNS production in phagocytes";"RHO GTPases Activate NADPH Oxidases";"VEGFA-VEGFR2 Pathway" XP_008556247.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_008543818.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014300908.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_053594703.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_008547503.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_053596448.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_008549760.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014296890.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_008545157.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_008558380.3 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053598838.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" XP_008553301.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_053595622.1 17 Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744 "Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carnitine metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Glyoxylate assimilation" XP_053596076.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_008555118.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_053593010.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_008561093.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_008553857.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_008545712.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_014296187.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_008549006.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_008546022.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_053594430.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_008548692.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_008558276.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_053599031.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" XP_008554752.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_008553187.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_008545190.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014296857.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_008551643.1 7 Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-8854214 "Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs" XP_008556556.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008561096.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_008549185.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008546970.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_008549606.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008543720.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_008543670.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_008545132.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_053598761.1 17 Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-9020702 "Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling" XP_053597612.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_008550619.1 17 Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949 "DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA" XP_053596712.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053597626.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_053598936.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_008546249.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_053594707.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_014300278.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014295525.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex" XP_008548311.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_008544835.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_008544999.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_008547608.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" NP_001401729.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008549718.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_053597366.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_053594651.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_008550246.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932 "Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Trafficking of AMPA receptors";"NrCAM interactions";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules" XP_008546708.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_053593429.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014295593.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008553853.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014300020.1 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7338 "Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_053596891.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_014298268.1 5 KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_053596883.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_008545968.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_008560296.1 18 MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC" XP_008556658.2 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_008554925.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_053597745.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_053596645.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_053597383.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_053597391.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_053593945.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_014299464.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_008555184.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_008550557.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_053598155.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_053594874.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_008560509.1 10 Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_008545262.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_008550658.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_008553344.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008555343.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_014296853.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107 "SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_008556424.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport" XP_008549370.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_008559992.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_008555889.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_053596045.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_053593206.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_008555721.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788 "HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling" XP_008544967.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_008554113.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_053598015.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_053594111.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_053595673.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_053599003.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008555455.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_053596974.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_008557029.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_008555619.1 10 MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174 "Ferrichrome A biosynthesis";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)" XP_008545560.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_008556079.1 11 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_008545613.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_008552289.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_008546914.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_008547023.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695 "HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation" XP_008551909.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014296333.1 13 MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_008549496.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_008545559.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_053595341.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_053593181.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_008550347.1 52 Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-202424 "Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAPK6/MAPK4 signaling";"Degradation of DVL";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling" XP_008556151.1 13 KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-6370;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061 "Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I" XP_053594966.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_008545974.1 179 Reactome: R-HSA-1358803;Reactome: R-HSA-1295596;Reactome: R-HSA-182971;Reactome: R-HSA-1799339;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-3134975;Reactome: R-HSA-8876493;Reactome: R-HSA-174178;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-9013507;Reactome: R-HSA-937039;Reactome: R-HSA-9636383;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-6804756;Reactome: R-HSA-174490;Reactome: R-HSA-5678895;Reactome: R-HSA-400253;Reactome: R-HSA-3322077;Reactome: R-HSA-2173796;Reactome: R-HSA-2559582;Reactome: R-HSA-8852276;Reactome: R-HSA-5689901;Reactome: R-HSA-5684264;Reactome: R-HSA-110312;Reactome: R-HSA-9637628;Reactome: R-HSA-5632684;Reactome: R-HSA-2173791;Reactome: R-HSA-975110;Reactome: R-HSA-9645460;Reactome: R-HSA-6807004;Reactome: R-HSA-162588;Reactome: R-HSA-917937;Reactome: R-HSA-937041;Reactome: R-HSA-5675221;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-2979096;Reactome: R-HSA-6781823;Reactome: R-HSA-975163;Reactome: R-HSA-8849469;Reactome: R-HSA-5693565;Reactome: R-HSA-68827;Reactome: R-HSA-901032;Reactome: R-HSA-5656169;Reactome: R-HSA-2173788;Reactome: R-HSA-5675482;Reactome: R-HSA-4641263;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-156902;Reactome: R-HSA-75815;Reactome: R-HSA-5656121;Reactome: R-HSA-450321;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-6791226;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-69541;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-192823;Reactome: R-HSA-349425;Reactome: R-HSA-975956;Reactome: R-HSA-5357905;Reactome: R-HSA-917729;Reactome: R-HSA-2565942;Reactome: R-HSA-1253288;Reactome: R-HSA-175474;Reactome: R-HSA-5607761;Reactome: R-HSA-9615710;Reactome: R-HSA-9014325;Reactome: R-HSA-2173795;Reactome: R-HSA-6804760;Reactome: R-HSA-6782210;Reactome: R-HSA-5205685;Reactome: R-HSA-8875360;Reactome: R-HSA-9646399;Reactome: R-HSA-5685942;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-8948747;Reactome: R-HSA-6783310;Reactome: R-HSA-174154;Reactome: R-HSA-5693607;Reactome: R-HSA-912631;Reactome: R-HSA-2644606;Reactome: R-HSA-2408557;Reactome: R-HSA-2672351;Reactome: R-HSA-936964;Reactome: R-HSA-8866652;Reactome: R-HSA-68949;Reactome: R-HSA-1169408;Reactome: R-HSA-174113;Reactome: R-HSA-5654733;Reactome: R-HSA-8951664;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-2122948;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-1236382;Reactome: R-HSA-6782135;Reactome: R-HSA-2559580;Reactome: R-HSA-5362768;Reactome: R-HSA-2691232;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-168927;Reactome: R-HSA-2122947;Reactome: R-HSA-5357956;Reactome: R-HSA-174048;Reactome: R-HSA-936440;Reactome: R-HSA-209560;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-5689896;Reactome: R-HSA-9613829;Reactome: R-HSA-9633012;Reactome: R-HSA-8854050;Reactome: R-HSA-168638;Reactome: R-HSA-3785653;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-3769402;Reactome: R-HSA-977225;Reactome: R-HSA-110314;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-5654732;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5655862;Reactome: R-HSA-4608870;Reactome: R-HSA-5654726;Reactome: R-HSA-975144;Reactome: R-HSA-5668541;Reactome: R-HSA-201681;Reactome: R-HSA-8866654;Reactome: R-HSA-6804757;Reactome: R-HSA-179409;Reactome: R-HSA-72706;Reactome: R-HSA-174084;Reactome: R-HSA-9013973;Reactome: R-HSA-8856828;Reactome: R-HSA-110320;Reactome: R-HSA-532668;Reactome: R-HSA-937042;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-205043;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-72689;Reactome: R-HSA-8863795;Reactome: R-HSA-937072;Reactome: R-HSA-8941858;Reactome: R-HSA-2559585;Reactome: R-HSA-975957;Reactome: R-HSA-209543;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-168928;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-9033241 "Downregulation of ERBB2:ERBB3 signaling";"Spry regulation of FGF signaling";"EGFR downregulation";"SRP-dependent cotranslational protein targeting to membrane";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of innate immune responses to cytosolic DNA";"InlA-mediated entry of Listeria monocytogenes into host cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"IRAK1 recruits IKK complex";"Prevention of phagosomal-lysosomal fusion";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Membrane binding and targetting of GAG proteins";"Defective CFTR causes cystic fibrosis";"Circadian Clock";"Glycogen synthesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Senescence-Associated Secretory Phenotype (SASP)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Metalloprotease DUBs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Translesion synthesis by REV1";"Modulation by Mtb of host immune system";"Hedgehog 'on' state";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of MET activity";"Budding and maturation of HIV virion";"Iron uptake and transport";"IKK complex recruitment mediated by RIP1";"Negative regulation of MAPK pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Formation of TC-NER Pre-Incision Complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"CDT1 association with the CDC6:ORC:origin complex";"ER Quality Control Compartment (ERQC)";"Termination of translesion DNA synthesis";"Downregulation of TGF-beta receptor signaling";"Regulation of necroptotic cell death";"Regulation of FZD by ubiquitination";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Peptide chain elongation";"Ubiquitin-dependent degradation of Cyclin D";"Translesion synthesis by POLI";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Stabilization of p53";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Viral mRNA Translation";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of TNFR1 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of ERBB4 signaling";"Assembly Of The HIV Virion";"Dectin-1 mediated noncanonical NF-kB signaling";"Late endosomal microautophagy";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of TP53 Activity through Methylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pink/Parkin Mediated Mitophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"Aggrephagy";"HDR through Homologous Recombination (HRR)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN localization";"Fanconi Anemia Pathway";"APC/C:Cdc20 mediated degradation of Securin";"Processing of DNA double-strand break ends";"Regulation of signaling by CBL";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Selenocysteine synthesis";"Stimuli-sensing channels";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Orc1 removal from chromatin";"ISG15 antiviral mechanism";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of FGFR4 signaling";"Neddylation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Dual incision in TC-NER";"Oxidative Stress Induced Senescence";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TICAM1, RIP1-mediated IKK complex recruitment";"NOTCH1 Intracellular Domain Regulates Transcription";"TNFR1-induced NFkappaB signaling pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"Negative regulators of DDX58/IFIH1 signaling";"NF-kB is activated and signals survival";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ovarian tumor domain proteases";"Chaperone Mediated Autophagy";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NOD1/2 Signaling Pathway";"Myoclonic epilepsy of Lafora";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Deactivation of the beta-catenin transactivating complex";"Amyloid fiber formation";"Recognition of DNA damage by PCNA-containing replication complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Negative regulation of FGFR3 signaling";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLK";"Asymmetric localization of PCP proteins";"Negative regulation of FGFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TNFR2 non-canonical NF-kB pathway";"TCF dependent signaling in response to WNT";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Degradation";"APC-Cdc20 mediated degradation of Nek2A";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Autodegradation of Cdh1 by Cdh1:APC/C";"TICAM1-dependent activation of IRF3/IRF7";"Clathrin-mediated endocytosis";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK2 mediated activation of TAK1 complex";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"UCH proteinases";"NRIF signals cell death from the nucleus";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Formation of a pool of free 40S subunits";"Downregulation of ERBB2 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of RUNX3 expression and activity";"Oncogene Induced Senescence";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"p75NTR recruits signalling complexes";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Peroxisomal protein import" XP_008543485.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014299769.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors" XP_053595914.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053593913.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_053598034.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_008554519.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_053596560.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008560665.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_053595073.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008552131.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_008556215.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008546341.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-68949 "UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin" XP_053596559.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_008554653.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-165054 "SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA" XP_008543591.1 10 Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_008548379.1 10 MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" XP_008555334.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014295167.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_008552474.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_008558799.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_008543339.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008548219.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_053593239.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_008558823.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_008560242.1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-3000471 "Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"VLDL assembly";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"LDL clearance";"Post-translational protein phosphorylation";"Chylomicron assembly";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"VLDL clearance";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Scavenging by Class B Receptors" XP_008551940.1 5 KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757 "Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines" XP_053598460.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_053596717.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008546498.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_008546528.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_014296476.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_014300635.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism" XP_053594628.1 30 Reactome: R-HSA-180534;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-5607761;Reactome: R-HSA-2122947;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-2644606 "Vpu mediated degradation of CD4";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_053597617.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-111932 "Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB" XP_008556065.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_008547578.1 7 Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191 "Synthesis of PE";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC" XP_008543927.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008546140.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873 "Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_008547727.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_053594527.1 10 KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_053598042.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008544718.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014300583.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_014297561.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_008551135.1 18 Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482801 "Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS" XP_008558086.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_014300339.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_008555342.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_008553837.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_008555470.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_008547645.2 6 MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17 "Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Caprolactam degradation" XP_008551734.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3 "Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism" XP_008554757.1 33 Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-69656;Reactome: R-HSA-8939236;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-112382 "Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex" XP_008560151.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-3214842;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110331 "Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"HDMs demethylate histones";"PKMTs methylate histone lysines";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HCMV Early Events";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged purine" XP_014299081.1 26 Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-8866654;Reactome: R-HSA-1362277;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-69205;Reactome: R-HSA-4615885;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169 "Dual incision in TC-NER";"Polymerase switching";"E3 ubiquitin ligases ubiquitinate target proteins";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"G1/S-Specific Transcription";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis" XP_053593364.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_053596286.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_008559671.3 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_053594450.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_008550621.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_008556350.1 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_008554930.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_053599051.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_053597382.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_008548669.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_053597204.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_008544138.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014300035.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_008546386.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_008560881.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_008543280.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_008557850.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_008550685.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_008556846.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_008555758.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_014299681.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_053598265.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_008544370.1 34 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-9639288;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Amino acids regulate mTORC1";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly" XP_008558436.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702 "Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition" XP_008544820.1 33 Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_008560825.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_008558686.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_014296473.2 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_008553476.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_053598696.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_053599111.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_008558822.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_008557556.1 18 KEGG: 00380+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70268;MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00640+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71064;KEGG: 00020+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-5362517;MetaCyc: PWY-5084;Reactome: R-HSA-6783984;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4 "Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Lysine catabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine degradation";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation" XP_008560102.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_008543582.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014296357.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_008547580.1 7 MetaCyc: PWY-7782;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213 "Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis of PE" XP_008550815.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_008556261.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_008557330.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_053593710.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014300884.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_053597726.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-68949 "NIK-->noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin" XP_008551439.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_008551321.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_053597910.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_008544512.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_008549434.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_008547616.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_053595287.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_008543972.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_008546920.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_008556296.1 4 KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" XP_008549059.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833 "RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly" XP_053595136.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_008555488.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_008548730.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_053593192.1 41 Reactome: R-HSA-5654719;Reactome: R-HSA-190322;Reactome: R-HSA-8853338;Reactome: R-HSA-5654689;Reactome: R-HSA-5655253;Reactome: R-HSA-2033519;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-190372;Reactome: R-HSA-190377;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-5654704;Reactome: R-HSA-190371;Reactome: R-HSA-2033514;Reactome: R-HSA-5654221;Reactome: R-HSA-5654693;Reactome: R-HSA-190370;Reactome: R-HSA-5673001;Reactome: R-HSA-5654228;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-190373;Reactome: R-HSA-5654700;Reactome: R-HSA-5654695;Reactome: R-HSA-5654733;Reactome: R-HSA-5654687;Reactome: R-HSA-5654710;Reactome: R-HSA-5654706;Reactome: R-HSA-190375;Reactome: R-HSA-5654720;Reactome: R-HSA-2219530;Reactome: R-HSA-5654727;Reactome: R-HSA-1839122;Reactome: R-HSA-5654227;Reactome: R-HSA-8851708;Reactome: R-HSA-5654732;Reactome: R-HSA-1839130;Reactome: R-HSA-1257604;Reactome: R-HSA-5654726 "SHC-mediated cascade:FGFR4";"FGFR4 ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"PI-3K cascade:FGFR1";"Signaling by FGFR2 in disease";"Activated point mutants of FGFR2";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"FGFR3c ligand binding and activation";"FGFR2b ligand binding and activation";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR3";"FGFR3b ligand binding and activation";"FGFR3 mutant receptor activation";"Phospholipase C-mediated cascade, FGFR2";"FRS-mediated FGFR1 signaling";"FGFR1b ligand binding and activation";"RAF/MAP kinase cascade";"Phospholipase C-mediated cascade, FGFR4";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR1c ligand binding and activation";"FRS-mediated FGFR2 signaling";"PI-3K cascade:FGFR2";"Negative regulation of FGFR4 signaling";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR3";"FRS-mediated FGFR3 signaling";"FGFR2c ligand binding and activation";"PI-3K cascade:FGFR4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR2 signaling";"Signaling by activated point mutants of FGFR1";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR2 IIIa TM";"Negative regulation of FGFR3 signaling";"Signaling by activated point mutants of FGFR3";"PIP3 activates AKT signaling";"Negative regulation of FGFR1 signaling" XP_014298018.1 12 MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-7901 "Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine" XP_014300154.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_053593828.1 10 MetaCyc: PWY-3821;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6317 "D-galactose detoxification";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)" XP_053593218.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_053594764.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_008547564.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_008555396.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_008558918.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_008559653.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_008551654.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events" XP_014296332.1 13 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_014295477.1 12 Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553 "Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs" XP_053594165.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_053596026.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_008548110.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158 "Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V" XP_053595672.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_008558409.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_008554538.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_053594214.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_008550758.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014299715.2 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_008546008.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_053594824.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_008552825.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis" XP_008555397.2 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_008560619.2 8 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_008545383.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053593302.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_014299403.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_008550297.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014300670.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_053597968.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_014300193.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_053594129.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_053593284.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs" XP_053597045.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_008556131.1 7 KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway" XP_008552881.1 4 KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801 "Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion" XP_008546608.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-68827 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex" XP_053593260.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_008550470.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_053593479.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation" XP_014300818.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_014299990.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_008558959.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_008550269.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_008546862.1 26 Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-918233 "FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway" XP_008546955.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_053598439.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_008549618.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_053594751.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_008543655.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_053593831.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_008555414.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_008548221.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014300074.2 5 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-8963896;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"HDL assembly";"Crosslinking of collagen fibrils" XP_008554491.1 41 Reactome: R-HSA-5654720;Reactome: R-HSA-2219530;Reactome: R-HSA-1839122;Reactome: R-HSA-5654727;Reactome: R-HSA-8851708;Reactome: R-HSA-5654732;Reactome: R-HSA-5654227;Reactome: R-HSA-5654726;Reactome: R-HSA-1257604;Reactome: R-HSA-1839130;Reactome: R-HSA-6811558;Reactome: R-HSA-5654695;Reactome: R-HSA-5654733;Reactome: R-HSA-190373;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5654687;Reactome: R-HSA-5654710;Reactome: R-HSA-190375;Reactome: R-HSA-5654704;Reactome: R-HSA-5654221;Reactome: R-HSA-190371;Reactome: R-HSA-2033514;Reactome: R-HSA-5654693;Reactome: R-HSA-190370;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-5654228;Reactome: R-HSA-190322;Reactome: R-HSA-8853338;Reactome: R-HSA-5654719;Reactome: R-HSA-5654689;Reactome: R-HSA-5655253;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-2033519;Reactome: R-HSA-5654219;Reactome: R-HSA-5654699;Reactome: R-HSA-190377;Reactome: R-HSA-190372 "PI-3K cascade:FGFR4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by activated point mutants of FGFR1";"Negative regulation of FGFR2 signaling";"Signaling by FGFR2 IIIa TM";"Negative regulation of FGFR3 signaling";"Phospholipase C-mediated cascade, FGFR3";"Negative regulation of FGFR1 signaling";"PIP3 activates AKT signaling";"Signaling by activated point mutants of FGFR3";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR2";"Negative regulation of FGFR4 signaling";"FGFR1c ligand binding and activation";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR3";"FGFR2c ligand binding and activation";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR2";"FGFR3b ligand binding and activation";"FGFR3 mutant receptor activation";"FRS-mediated FGFR1 signaling";"FGFR1b ligand binding and activation";"RAF/MAP kinase cascade";"PI3K Cascade";"Phospholipase C-mediated cascade, FGFR4";"FGFR4 ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR1";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"Activated point mutants of FGFR2";"Phospholipase C-mediated cascade: FGFR1";"SHC-mediated cascade:FGFR2";"FGFR2b ligand binding and activation";"FGFR3c ligand binding and activation" XP_008554483.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_008554521.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_008544639.1 5 Reactome: R-HSA-197264;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation" XP_053596383.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_053592974.1 13 MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_008554975.1 6 Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-3878781 "Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)" XP_008550250.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244 "Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation" XP_008559558.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_008557611.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_008553515.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_053593259.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_053597891.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_008556289.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_008545133.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_053597613.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-111932 "Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB" XP_008544962.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_008560765.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_008558067.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_008554044.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_053596713.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_008544855.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_008555139.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_008548174.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_053594523.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" XP_008544603.2 15 Reactome: R-HSA-167246;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382 "Tat-mediated elongation of the HIV-1 transcript";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex" XP_008553929.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008556779.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_053593351.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_008548775.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_053593807.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_008558395.1 12 MetaCyc: PWY-7343;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801 "UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)" XP_008556381.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_008555834.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_008548879.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_053595095.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008544759.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_008557215.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress" XP_008548693.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_053595367.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_014299650.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_008558699.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-525793 "Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Myogenesis" XP_014300688.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_008557375.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_053594425.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_008550537.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_053598406.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_053594031.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_008545713.1 5 KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_008557989.3 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_053592883.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_008546023.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_053595623.1 17 MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-3371599 "Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_008558667.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_053596924.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_053598734.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_008554644.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972 "Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)" XP_053596267.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_014299697.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014297698.2 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_008543500.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_008550847.1 13 Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-450302 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation" XP_008544784.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496 "Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs" XP_014300206.2 1 Reactome: R-HSA-8964038 "LDL clearance"