Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_015520255.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015515742.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046597269.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015511855.1	30	Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-2564830;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Cytosolic iron-sulfur cluster assembly";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046593835.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046601837.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593776.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747	"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated"
XP_046588863.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015512829.2	5	Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
XP_015523237.2	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046585752.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_046590683.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_015512271.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_015513911.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_015514156.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_015517687.2	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_015512208.2	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_046599612.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046600212.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046599667.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_015515711.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046598236.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046600332.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046596846.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015522462.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_015514669.2	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015517003.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258	"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL"
XP_015513570.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015513157.1	29	Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape"
XP_046586825.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_015516712.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015516570.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046587427.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_046595572.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046598135.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_015511588.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_046594957.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_015515558.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015519981.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_015519248.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046600514.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046590282.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046588591.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_015512358.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046593842.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015522920.1	5	KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
XP_046593989.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_015518525.2	7	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_015522364.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046588127.1	7	KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;MetaCyc: PWY-7158	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"L-phenylalanine degradation V"
XP_015515467.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_015515719.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046587602.1	32	Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-72165	"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway"
XP_015516857.2	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_015517830.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015517923.2	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015511125.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862	"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046600042.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015519874.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015518025.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015519931.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015518087.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion"
XP_046591760.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046599175.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046597250.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562	"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog 'on' state";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)"
XP_046595855.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588069.1	13	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_015514466.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015519612.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046591290.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046589954.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046589694.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_015519759.1	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis"
XP_015517180.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046602334.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_015513971.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015511862.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_015509232.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046599958.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_046588323.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_015510583.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046589469.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex"
XP_046591067.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015519540.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015514815.2	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046588196.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015521133.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015518565.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015516218.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
XP_015512695.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046593682.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_015517291.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015517382.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046595852.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897	"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"Macroautophagy";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes"
XP_046594804.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046601270.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046598620.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723	"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation"
XP_015522740.1	25	Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-8941284;Reactome: R-HSA-8939242;Reactome: R-HSA-8877330;Reactome: R-HSA-8931987;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8941326;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-8949275;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8939246	"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates bone development";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells"
XP_015520012.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015521120.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015523951.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046602565.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046601710.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_046598582.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046589862.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_015522636.1	7	Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_046591289.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_046595664.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_015522915.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046597140.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046594278.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015520569.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015510042.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046593690.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_015522216.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_015523828.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015524628.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046599986.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_015513765.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046590391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046593890.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046598748.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046601011.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046597205.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046596785.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015515641.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601351.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046588915.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046595929.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046598819.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_015512717.2	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_015510328.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046600662.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046594367.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy"
XP_046596915.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015519251.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046592407.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_015524347.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015516868.2	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_046596490.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046596118.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046596043.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046587897.1	19	MetaCyc: PWY-7115;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7383	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methane metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_015522546.1	7	Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-156827	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046599544.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_046602656.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046601834.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015521479.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046592962.1	14	MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046593723.1	14	Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400	"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER"
XP_015517996.2	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046600500.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046592039.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_015516228.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597381.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_046591044.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015510618.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167160	"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_046600922.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046601122.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015515816.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046588195.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046590910.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015512229.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046591248.1	44	Reactome: R-HSA-445144;Reactome: R-HSA-879415;Reactome: R-HSA-3371453;Reactome: R-HSA-6802952;Reactome: R-HSA-9627069;Reactome: R-HSA-202670;Reactome: R-HSA-2559582;Reactome: R-HSA-5668599;Reactome: R-HSA-74749;Reactome: R-HSA-198753;Reactome: R-HSA-8940973;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-8939211;Reactome: R-HSA-5654733;Reactome: R-HSA-162658;Reactome: R-HSA-5673001;Reactome: R-HSA-881907;Reactome: R-HSA-2559585;Reactome: R-HSA-170968;Reactome: R-HSA-8943724;Reactome: R-HSA-9635465;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-982772;Reactome: R-HSA-9649948;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-375165;Reactome: R-HSA-2559580;Reactome: R-HSA-5674135;Reactome: R-HSA-112409;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5663213;Reactome: R-HSA-2871796;Reactome: R-HSA-5674499;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-5675221;Reactome: R-HSA-1295596;Reactome: R-HSA-444257;Reactome: R-HSA-6802948	"Signal transduction by L1";"Advanced glycosylation endproduct receptor signaling";"Regulation of HSF1-mediated heat shock response";"Signaling by BRAF and RAF fusions";"Regulation of the apoptosome activity";"ERKs are inactivated";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate NADPH Oxidases";"Signal attenuation";"ERK/MAPK targets";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"ESR-mediated signaling";"Negative regulation of FGFR4 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"RAF/MAP kinase cascade";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oncogene Induced Senescence";"Frs2-mediated activation";"Regulation of PTEN gene transcription";"Suppression of apoptosis";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"Growth hormone receptor signaling";"Signaling downstream of RAS mutants";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"NCAM signaling for neurite out-growth";"Oxidative Stress Induced Senescence";"MAP2K and MAPK activation";"RAF-independent MAPK1/3 activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"FCERI mediated MAPK activation";"Negative feedback regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of MAPK pathway";"Spry regulation of FGF signaling";"RSK activation";"Signaling by high-kinase activity BRAF mutants"
XP_046601471.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_015511896.2	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_046591802.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046595153.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_015512481.2	5	Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-209543	"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"p75NTR recruits signalling complexes"
XP_046594145.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046593249.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046595489.1	10	MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559	"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway"
XP_046593815.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046589317.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_015520923.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046591837.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015519543.1	11	Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42	"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes"
XP_015514171.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046595870.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015523204.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046600334.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_015522102.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_015524542.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_015514210.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_015509947.2	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046590988.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046592343.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-195399;Reactome: R-HSA-194313	"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions"
XP_046587034.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_015524339.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_015523288.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046595211.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_015513744.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015514638.2	14	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity"
XP_015518089.1	4	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015509497.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046594862.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015521398.2	8	Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-432720	"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis"
XP_046592821.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046595932.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_015518616.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015519753.2	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_015521033.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015517615.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_015518263.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046599793.1	8	KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_046589836.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_015515848.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015516232.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046590118.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046593270.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_015521195.1	8	KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046593866.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_046591489.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_015518232.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046595787.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015513406.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046587233.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015517241.2	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_015516042.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046593719.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_015513129.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046592402.1	5	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201	"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I"
XP_015524911.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046587784.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_015510242.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_015520075.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_046602248.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015510210.2	20	MetaCyc: PWY-7288;MetaCyc: PWY-735;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_046587991.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015510402.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015514600.1	12	KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II"
XP_015510393.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015514465.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015522074.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_015520095.2	4	Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_015520716.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_015518521.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_046600495.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015510312.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046594236.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015523921.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_015514962.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015523993.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_015521347.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015520216.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_015511845.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_015510690.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046596247.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_015521352.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046602799.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015517756.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046592226.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015510585.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046596175.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426496	"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs"
XP_015509262.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_015511951.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046595782.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015516366.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015512379.2	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_015519161.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015523653.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046592394.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046589068.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_015522094.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046589901.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046602504.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046589360.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046586306.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation"
XP_015513776.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046585951.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046594126.1	11	KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657	"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes"
XP_015515402.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015516726.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046600298.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_015509834.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600304.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046597729.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015509636.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015516644.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046597187.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_046598701.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046586206.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046599154.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046586605.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_046594004.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015520947.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_015516359.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_015520420.2	57	Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276	"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046586709.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046601195.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046600839.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_015523851.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_015511814.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046594231.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015517986.2	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046601202.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_015524442.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015524034.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_015512149.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015519781.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_015513063.1	60	Reactome: R-HSA-77288;MetaCyc: PWY-5177;MetaCyc: PWY-6944;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5109;MetaCyc: PWY-5789;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5136;Reactome: R-HSA-77348;MetaCyc: PWY-5138;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77346;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00720+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;Reactome: R-HSA-1482798;MetaCyc: PWY-7007;MetaCyc: PWY-6863;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;Reactome: R-HSA-77350;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7726	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Glutaryl-coa degradation";"Androstenedione degradation";"Butanoate metabolism";"Geraniol degradation";"Butanoate metabolism";"Benzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Valine, leucine and isoleucine degradation";"Toluene degradation";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Caprolactam degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Acyl chain remodeling of CL";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Aminobenzoate degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Fatty acid salvage";"Fatty acid elongation";"Lysine degradation";"Benzoate degradation";"Tryptophan metabolism";"Caprolactam degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Lysine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_015509322.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection"
XP_046589551.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_015513918.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015514796.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046588180.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596177.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944	"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2"
XP_046597958.1	22	MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7725	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046590752.1	7	MetaCyc: PWY-6605;Reactome: R-HSA-74217;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807	"Adenine and adenosine salvage II";"Purine salvage";"Adenine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Purine metabolism";"Glyphosate degradation III"
XP_046595051.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events"
XP_015521622.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046601268.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015515354.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046593500.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_015516327.1	8	MetaCyc: PWY-7199;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-73614	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage"
XP_015509639.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046585805.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_015514305.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015510545.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046598704.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046594291.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_046598984.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046593768.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015509165.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046592204.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_015518760.2	13	Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178	"NCAM1 interactions";"Extracellular matrix organization";"Collagen degradation";"Laminin interactions";"Integrin cell surface interactions";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans"
XP_046600881.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_015517535.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_015516969.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015524773.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046597975.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_015519808.2	52	Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Neddylation";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog 'on' state"
XP_015514930.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_015521362.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046593824.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046591204.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_046589119.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046591183.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015520141.1	8	KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_015512622.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015512697.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046598864.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_015517694.2	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_015509690.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_015513341.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508	"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_015520001.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015513521.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_015521687.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046597080.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015524430.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046594733.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046595812.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046592476.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046601539.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046592127.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_046601241.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015523662.1	22	Reactome: R-HSA-70263;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-5659;MetaCyc: PWY-7385;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6981;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-6992;MetaCyc: PWY-7238;MetaCyc: PWY-5514;MetaCyc: PWY-621;MetaCyc: PWY-7347;MetaCyc: PWY-3801;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5054;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-622	"Gluconeogenesis";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"GDP-mannose biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Chitin biosynthesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch and sucrose metabolism";"Neutrophil degranulation";"1,5-anhydrofructose degradation";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"Sucrose biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"D-sorbitol biosynthesis I";"Glycolysis / Gluconeogenesis";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis"
XP_015510094.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_046595912.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_015512631.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046595165.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_015514690.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_046601189.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046595133.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046590685.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046600386.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015520182.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_046593433.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_046599754.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015517660.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046589433.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015518866.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046600869.1	52	Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046586757.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589012.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046602700.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015524949.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3	"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism"
XP_015518797.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046587097.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_015517216.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015518685.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-983231	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production"
XP_015509341.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015519865.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015521851.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_015518694.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253	"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Interleukin-1 signaling";"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex"
XP_015509438.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_015511525.2	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_046597999.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046590990.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_015513555.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015518785.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046586165.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_046599527.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594064.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_046602294.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046586763.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis"
XP_015523348.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9646399	"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Recycling pathway of L1";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy"
XP_046585688.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046590933.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046592054.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015516376.2	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_015517286.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_015511984.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_015514593.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_015520715.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere"
XP_046591586.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015516202.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-71403	"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)"
XP_046602622.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-168315;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Inhibition of Host mRNA Processing and RNA Silencing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046600407.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_015515722.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015521703.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_015516225.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_015514300.2	8	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5689880	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases"
XP_046592177.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Synthesis of PA"
XP_046592426.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_046590279.1	31	MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971	"Gondoate biosynthesis (anaerobic)";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_046595926.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_015511934.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046588431.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_046598689.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_046601641.1	4	MetaCyc: PWY-5668;MetaCyc: PWY-5269;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5	"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_046598905.1	39	Reactome: R-HSA-5654733;Reactome: R-HSA-1257604;Reactome: R-HSA-5654720;Reactome: R-HSA-5654719;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2033514;Reactome: R-HSA-190373;Reactome: R-HSA-5654712;Reactome: R-HSA-8853338;Reactome: R-HSA-5654699;Reactome: R-HSA-190372;Reactome: R-HSA-5654710;Reactome: R-HSA-5654688;Reactome: R-HSA-5654732;Reactome: R-HSA-1839130;Reactome: R-HSA-5658623;Reactome: R-HSA-190322;Reactome: R-HSA-5654219;Reactome: R-HSA-5655302;Reactome: R-HSA-5654227;Reactome: R-HSA-5654221;Reactome: R-HSA-2033519;Reactome: R-HSA-190371;Reactome: R-HSA-5654689;Reactome: R-HSA-5654687;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-1839122;Reactome: R-HSA-190375;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-5654700;Reactome: R-HSA-5655253;Reactome: R-HSA-5654704;Reactome: R-HSA-5654706;Reactome: R-HSA-5654228	"Negative regulation of FGFR4 signaling";"PIP3 activates AKT signaling";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR4";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade";"FGFR3 mutant receptor activation";"FGFR1c ligand binding and activation";"FRS-mediated FGFR4 signaling";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR2";"FGFR3c ligand binding and activation";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR1";"Negative regulation of FGFR3 signaling";"Signaling by activated point mutants of FGFR3";"FGFRL1 modulation of FGFR1 signaling";"FGFR4 ligand binding and activation";"Phospholipase C-mediated cascade: FGFR1";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade, FGFR3";"Phospholipase C-mediated cascade, FGFR2";"Activated point mutants of FGFR2";"FGFR3b ligand binding and activation";"PI-3K cascade:FGFR1";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Signaling by activated point mutants of FGFR1";"FGFR2c ligand binding and activation";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR2 signaling";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR3 signaling";"Phospholipase C-mediated cascade, FGFR4"
XP_046601600.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_015519112.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_046601496.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_015510659.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046599336.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046597521.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591139.1	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_046589132.1	8	Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade"
XP_046597007.1	9	Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695	"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events"
XP_046586623.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586073.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_015520488.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015514145.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046600227.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046588502.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591610.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015518871.1	8	MetaCyc: PWY-5269;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 04658+3.1.3.16	"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Synthesis of PG";"Th1 and Th2 cell differentiation"
XP_015522753.1	24	Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Recycling pathway of L1";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046592850.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_015509518.2	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_015510763.2	13	MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_046588864.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046587440.1	17	Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-445989	"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_046592648.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015522450.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046601187.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046591749.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-5099900;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis"
XP_015513878.2	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_046588222.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015512411.2	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704	"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade"
XP_046587596.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046590070.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere"
XP_046594877.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6"
XP_046592496.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046595743.1	33	Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-180746	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein"
XP_015511107.2	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046588058.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015517276.2	6	MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_015513372.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015517617.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046599895.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_015514192.2	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_046602009.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015512101.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046594855.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046585885.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046593123.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_015513155.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046587691.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_046588865.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046594873.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_015512204.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046599860.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046596275.1	4	Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047	"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol"
XP_046590165.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_015513595.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046600996.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_015509860.2	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_015517281.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046593778.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046593838.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015517645.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046589154.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_015521648.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015509722.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046599573.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046591065.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015522318.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046601832.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597953.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046590057.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597507.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046590981.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592849.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046599276.1	11	MetaCyc: PWY-6453;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4	"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_046587311.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046601983.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015513151.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046589545.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046601556.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046586126.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046599725.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046586914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046591567.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_046588408.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015513986.2	14	MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51	"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_015512623.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism"
XP_046601627.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_046588853.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046593070.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015518867.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_015511543.1	25	Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-381771;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-392170	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G-protein activation";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12"
XP_046599088.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015520326.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_015521191.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-139915	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria"
XP_015515090.1	6	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis II"
XP_015522097.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046593889.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046587523.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046602719.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015513395.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015513629.2	6	KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_046586719.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_015524585.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046596623.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_046592760.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046592397.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015517619.1	40	Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"Pausing and recovery of HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_046600385.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046596836.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046592447.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)"
XP_015519969.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046598635.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_015514255.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_015521186.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046592459.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046599249.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667	"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_046601126.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046591915.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046592799.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015522576.1	7	Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis"
XP_015524917.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046602263.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046591951.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_046599073.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_046596208.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046602262.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046593863.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015515840.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046599918.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046594292.1	8	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_046599919.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015514880.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_015513632.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046592124.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046595894.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015513723.1	7	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_015511539.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046601833.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591611.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015523674.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_015524315.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046588484.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_015521670.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_015523298.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046585812.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_046587785.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046600035.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015515942.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_046595630.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_015522564.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_046593247.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046602800.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046594721.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_015516126.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015514170.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_015519891.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015514684.1	19	Reactome: R-HSA-5389840;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_015520590.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046598274.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_015517401.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511241.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046587444.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events"
XP_015513211.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046601086.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046587701.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_015518609.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046590041.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015514172.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_015511502.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_015510116.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015519978.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015511802.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_046590992.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046600766.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046600994.1	8	MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"PPARA activates gene expression"
XP_046589506.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_015509819.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015518139.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015522639.1	16	Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_015520617.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015515563.2	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695	"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation"
XP_046599321.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046586373.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015518101.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046597039.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046589479.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046586125.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_015509303.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015513054.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518258.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015515419.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_015520843.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015522563.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_046598032.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046592448.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015512038.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046598985.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_046596300.1	17	Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"Thermogenesis"
XP_046596227.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015521032.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_046598700.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046594722.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_015520015.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046602434.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015521165.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015522506.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046600390.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015512166.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046594228.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046594678.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_015518942.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046597255.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046595635.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_046595862.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046597882.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015513897.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046597222.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015514424.2	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_015520946.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046590788.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_015510337.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_015519775.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_046595842.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046598798.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_046589162.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_046598224.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046593552.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046596847.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015517311.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046599475.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015515202.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_046601970.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015517406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015517997.2	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046586333.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_046598634.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046599751.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_046598260.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_015523880.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015512068.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046602112.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_046586131.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_015515801.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420	"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi"
XP_046598306.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_015509391.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"DSCAM interactions";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046587983.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_015517924.2	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015515220.2	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046598767.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046599779.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046594235.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015516418.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015516363.2	20	KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-380972	"Human papillomavirus infection";"Macroautophagy";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Human cytomegalovirus infection";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046586713.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_015511330.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046594532.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046597251.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015511682.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_046600084.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015517365.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_015511670.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046588894.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046595097.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_015524186.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_015514702.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_046593832.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046599823.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046594535.1	11	Reactome: R-HSA-210990;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-388841	"PECAM1 interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"PD-1 signaling";"Interferon alpha/beta signaling";"Costimulation by the CD28 family"
XP_015513100.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_015509254.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_015515115.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046598853.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046594928.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046596625.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015512886.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015524755.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015510227.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_046598851.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_015518395.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_015516257.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_046592049.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015510810.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046592677.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_015510627.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_015514404.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046599098.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015515383.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_046596400.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015519733.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046590308.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_046586519.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_015509136.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72649	"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Translation initiation complex formation"
XP_046601699.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015521694.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046590404.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015515253.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015523077.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_015512264.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046598142.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046596173.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723	"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation"
XP_015512363.2	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_015512789.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046595930.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046591662.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592125.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818	"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_046595171.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046599853.1	6	MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_046599845.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046598775.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046597260.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046588287.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046599234.1	7	KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Glutathione metabolism"
XP_046600575.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015516662.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_015523383.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046587521.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015524919.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046599298.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_046590690.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling"
XP_046594757.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015523792.1	6	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_015513760.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_015513083.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_015520418.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046595131.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015523833.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015511533.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046591494.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_015522291.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015521914.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015516523.1	7	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling"
XP_046589086.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046601784.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046592929.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015524598.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015512040.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015517443.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046596135.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046593644.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_015524358.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046597145.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046589195.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046596840.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_015510083.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_015515029.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601825.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015517168.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046589209.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046586905.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015519675.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046587845.1	13	MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_015510781.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541	"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Neddylation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway"
XP_046585939.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015514484.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_015514454.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046598048.1	13	KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2024101	"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"CS/DS degradation"
XP_046600106.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_015513274.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_015520832.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_015517317.2	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_015509318.2	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046599089.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046601480.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_046588773.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015519536.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046594000.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015515277.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
XP_015520056.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_015523207.2	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_015509297.1	9	Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110329	"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine"
XP_046595102.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_015518114.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015510098.2	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_015519985.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_015513232.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046590589.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046587682.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459	"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015520508.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046594162.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046596563.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015515148.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_015521691.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_046598537.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-5621575;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508	"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_015512629.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_015522653.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046588204.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015511982.2	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_046597221.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046587312.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015518177.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015517973.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586722.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015522281.2	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_046586484.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_046595100.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015520545.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046588456.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_015517835.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046595997.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015524658.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046595390.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015521645.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015515465.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046601280.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174084	"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_015520948.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_015510529.2	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046593290.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046599908.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_015510060.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-445989	"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_046588401.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015514774.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046598040.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015512625.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ATP biosynthesis";"Photosynthesis"
XP_015519349.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015515308.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-427413	"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression"
XP_046599058.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_015510304.2	18	MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Arachidonic acid metabolism"
XP_015523683.2	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_015510784.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015519104.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015509816.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046595057.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_015521805.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046586734.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015513053.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015514023.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Neddylation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_046599571.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046594680.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046597388.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_015509763.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046591160.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015521695.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015516772.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_046594048.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_046600403.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046601664.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015514979.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046602813.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015524637.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015517154.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015511100.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015510152.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_015510192.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_015516869.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046601997.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046586840.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_046593031.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046597886.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015510058.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_046593329.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_015520873.2	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_046587118.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046600862.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046601923.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_015514098.2	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_046592475.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046594511.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_015524910.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_015511389.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_046586301.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015521549.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046586520.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046597921.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046600772.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_046596821.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046600774.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_015514940.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046589813.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_015512231.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046593321.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
XP_015509988.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046599257.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015519211.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046595954.1	11	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_015523862.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-416993	"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors"
XP_046598347.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046598363.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046598714.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_015519463.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015512355.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046588244.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046596895.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_015511275.1	12	MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309	"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_015520398.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_046598235.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015519185.2	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_015524841.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046602233.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015511299.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046598631.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046586530.1	2	Reactome: R-HSA-442660;Reactome: R-HSA-352230	"Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane"
XP_046591985.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046588668.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_015516122.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_046594719.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_015519472.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046592129.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_015520463.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_015511806.1	13	MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
XP_015523372.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046602381.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518265.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046599174.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046595896.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_015523615.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046601772.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046600648.1	12	KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-174362;MetaCyc: PWY-6932	"Sulfur metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Selenate reduction"
XP_046602669.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046598695.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_015512029.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015510141.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_015514187.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046595692.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_015522603.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046595936.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_015519545.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_046592051.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_046599084.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015513899.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046590909.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046595090.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015519752.2	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_015524068.2	6	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_015513783.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015524916.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015523228.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_046600218.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_046594173.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015521577.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_015510794.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046587917.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_046594169.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046599572.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015522203.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046596023.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_015521077.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046601686.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015519297.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015519657.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_015523796.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046597192.1	11	MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-7586;Reactome: R-HSA-4043916	"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_015511190.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046601200.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_015518600.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015523317.2	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_046587328.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_015522737.1	13	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_046586377.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046593546.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046587955.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046590151.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_046600997.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046598589.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_015523685.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046593428.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512462.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015510527.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046599738.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_015521900.1	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046590097.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593496.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046588425.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046586511.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_015522823.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015521036.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_046593716.1	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046600402.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_015509840.2	16	Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_015515487.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174184	"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_015514595.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency"
XP_046589495.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5989;MetaCyc: PWY-7746;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858	"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II"
XP_015516296.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046595934.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046588202.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015518750.2	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046597488.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046591998.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015522377.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015513506.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015517948.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046587986.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015512444.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046593828.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015515863.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_015521258.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046588555.1	12	KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_046588769.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_046597879.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015520380.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015513731.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046591207.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046591957.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046592767.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046586162.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_046594225.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism"
XP_046590713.1	7	MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183	"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_015518269.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
XP_046598789.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-8876198	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"RAB GEFs exchange GTP for GDP on RABs"
XP_046595738.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_015517048.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_046598676.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046593769.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046594677.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_015513002.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046601451.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_046586818.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015514011.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015521580.2	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198	"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_015510355.2	3	Reactome: R-HSA-195399;Reactome: R-HSA-114608;Reactome: R-HSA-194313	"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation";"VEGF ligand-receptor interactions"
XP_015519948.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516	"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin"
XP_015518291.2	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_015511941.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046592308.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046595807.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015515428.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_015509193.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015521444.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046585769.1	58	Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Metalloprotease DUBs";"Hedgehog 'on' state";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Neddylation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Neutrophil degranulation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells"
XP_046594420.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046590054.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591511.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_015517242.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046594756.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046594244.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046599973.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046596810.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Heme biosynthesis"
XP_046600337.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046590581.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046590414.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046600707.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015512846.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_015519531.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046602683.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046599091.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015510930.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015522394.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015524489.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_015521850.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046588756.1	10	KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11	"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_046600899.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_046585748.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_015523011.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_015522760.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_015512888.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015510400.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046596336.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_015519115.1	13	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_046602234.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015510201.2	20	MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-7288	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_046593206.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015513759.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046586917.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015521325.2	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015521070.2	9	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-114604	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade"
XP_015522705.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_015518994.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015523357.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046596301.1	17	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632	"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis"
XP_046595417.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046595935.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046594857.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588553.1	12	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Rho GTPase cycle";"mTOR signaling pathway"
XP_046596491.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015514934.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015512083.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_046589390.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_015515775.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046597305.1	7	MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8	"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism"
XP_015521256.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046586564.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_046595810.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046586141.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_015509520.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_015523184.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046591894.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046600962.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015518136.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046598256.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046591916.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015519998.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046599665.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism"
XP_015524090.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046586718.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_015513137.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015519062.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046593291.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_015519961.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015522845.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046588165.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_046587786.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046601243.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015512656.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046598233.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046591799.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046597417.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_015510688.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-1268020	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial protein import"
XP_046596621.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046594607.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_046595028.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046589111.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015516031.1	7	MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7886	"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_015510174.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015523062.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_015512828.2	6	Reactome: R-HSA-3878781;MetaCyc: PWY-622;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_046599027.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_015511830.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_015520565.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046598624.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by VENTX"
XP_015517514.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_015516033.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818	"Glycerophospholipid metabolism";"Choline biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_046598377.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015522395.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046587441.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_046591281.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046590923.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046592172.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015510714.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_015518120.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046588290.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015509973.1	4	Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I";"Pentose and glucuronate interconversions"
XP_015515518.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_015519280.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_046602659.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046588416.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_015511346.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015524165.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_015512476.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046591495.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046594455.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015515005.1	4	Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_015517250.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046592835.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015515570.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046590002.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015519801.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046598579.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586907.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046600097.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046599461.1	10	Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508	"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_046587189.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015522899.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046592309.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046593856.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015520456.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_015513124.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_046598009.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7574	"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II"
XP_015522612.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046597523.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046587780.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046591987.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046597952.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015509701.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258	"Interleukin-1 signaling";"Hedgehog 'on' state";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL"
XP_046591886.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols"
XP_015519877.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046594402.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046594522.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046592759.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_015518546.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015520165.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046588385.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046587313.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_015519291.1	4	MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_015509392.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015510314.2	20	Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-110320	"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH"
XP_015515971.2	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_015515062.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_046598368.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046600096.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046595956.1	11	Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_046600963.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015513706.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015520707.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation"
XP_015510382.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046587501.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_015517383.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046589434.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015514013.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015517201.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_015515376.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_015512508.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046597130.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis"
XP_015522258.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015521246.2	14	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-500657;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_046598859.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046591751.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015522507.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046586727.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046591270.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046602008.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015517179.1	13	MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_046594348.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015522758.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_046591920.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046597202.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_015514849.2	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_015511547.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_015523830.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015509774.2	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_046597356.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046590337.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046592169.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015523486.2	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_015516211.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046586600.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_046588084.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046590905.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_046586726.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046588164.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046586209.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_046600512.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015510519.2	7	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends"
XP_046592147.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046594672.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_015518311.2	7	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes"
XP_046601993.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046593166.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046600292.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046594810.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015522731.2	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046588782.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_046598493.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_015514000.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis"
XP_015517260.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015522627.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046589768.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_015520131.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_046601277.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015521794.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046602244.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015512384.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046593617.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046595212.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046598355.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_015510166.2	10	Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-4661	"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_046595003.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015511349.2	16	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_046600551.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046586617.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015520859.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046597963.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_015510687.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation"
XP_015513177.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015522131.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046593852.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046590162.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015510057.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046590478.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046587493.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046601267.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015510298.1	16	MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5913;MetaCyc: PWY-5749;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.4;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392	"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II"
XP_015509476.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952	"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation"
XP_015517084.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046592873.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325	"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis"
XP_015511263.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_046593616.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_046598954.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_015511230.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_015521154.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046596212.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046601777.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015519476.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741	"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046589075.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046597572.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015523420.2	4	Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50	"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism"
XP_046586735.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046591824.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046598871.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592445.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_015520618.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015518879.2	7	Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA"
XP_046595696.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_046592121.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015515681.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_015509616.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046595927.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046601315.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046598747.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046595122.1	24	Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418217	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"G-protein activation";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta"
XP_015522790.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046593710.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046598041.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586538.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_015524345.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046590555.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046599384.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015522338.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046596241.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_015510795.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591386.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046586311.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy"
XP_046594606.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015521535.2	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_046595213.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_046597082.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015514538.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-112382	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex"
XP_046586176.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Interleukin-1 signaling";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_046599341.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046601109.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_046587244.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_015509954.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015524698.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015522676.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015513148.1	58	Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-5689901;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8951664	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"Metalloprotease DUBs";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Neddylation"
XP_046597306.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046592707.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015523364.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_015523084.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046599406.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046587610.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015515850.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_015513825.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression"
XP_046586913.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015515325.2	4	KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis"
XP_015514003.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046586534.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_046594041.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046593849.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046592036.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015516838.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046591057.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046596101.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015523557.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046592967.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_046601774.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046587433.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_015511391.2	8	Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_046593818.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046597591.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046599426.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015519374.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015516192.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046600210.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_015513635.2	6	MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis"
XP_046598692.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046590393.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015515021.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-8852276	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046592736.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015522975.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588946.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046586374.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586225.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046592443.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046587782.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046599090.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046591167.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046599814.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015513873.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_046587790.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046595017.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_046588891.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_015519958.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046598044.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046595235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597040.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046594986.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015518520.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_015522875.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046596264.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046592379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015523314.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046592056.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_015518768.1	9	KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5	"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis"
XP_046586274.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046594193.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046598217.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis"
XP_046595172.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046594021.1	7	MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)"
XP_015519340.2	4	MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20	"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism"
XP_046601888.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046599363.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_015516947.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_015510371.2	5	Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_015516059.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_015518978.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_015519992.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_015513514.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015524137.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_015513171.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046599932.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046587908.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046596273.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus"
XP_015522795.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015517214.2	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_046590290.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015509140.1	4	MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis"
XP_046592331.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015513357.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046599726.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015510399.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_015516656.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046601870.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_015523769.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046591891.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015516058.1	7	Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_015517184.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046600450.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046601494.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_046600229.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015513888.2	26	Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877	"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases Activate Formins";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase"
XP_015521193.1	8	KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism"
XP_015513130.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046602022.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes"
XP_015510139.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046598382.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_015513123.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Rap1 signalling";"Ca2+ pathway";"cGMP effects"
XP_046602193.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046595495.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_046593461.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation"
XP_015520653.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046588920.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015518241.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015517690.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_015520417.2	17	Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5358606	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046585708.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015518437.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-168315;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Inhibition of Host mRNA Processing and RNA Silencing";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046595573.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589193.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046593124.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046592072.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_015516785.1	24	Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-392851	"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"G-protein activation";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor"
XP_046589980.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046602051.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_015513437.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_015523580.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046602505.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046588388.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046601838.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046600275.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046600920.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046587500.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_046601826.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518092.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015523916.2	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_046597832.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015522819.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015516169.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046599799.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046597878.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046599322.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_015518593.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015516814.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046597950.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_015514405.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046595948.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302	"Human immunodeficiency virus 1 infection";"p38MAPK events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_046594250.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046599682.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046589160.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046598860.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046601347.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015521586.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046594515.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046601342.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046598410.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_015518310.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_046598038.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism"
XP_046594417.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_046601424.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_046597376.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_015519555.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_046594161.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046587062.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_015522134.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046593775.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046595220.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_015513826.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519	"Attenuation phase";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression"
XP_046586621.1	3	MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3	"Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism"
XP_015521767.2	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046586133.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_015513331.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015523976.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824	"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis"
XP_015522861.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_015512155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046596367.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_015513623.2	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_046589378.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046599482.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_015517405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015518665.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_046597773.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_046590562.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046589318.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69656	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046598219.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_015513253.1	11	Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-6804114	"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_046599773.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046595744.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046594618.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015516357.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046601271.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015523027.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046595695.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015512504.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046595933.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046593862.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046593679.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_046600300.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_015512506.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_046597850.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism"
XP_015516056.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_015519857.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046600960.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015521769.2	1	Reactome: R-HSA-156581	"Methylation"
XP_015514022.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_015516795.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046590156.1	13	MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism"
XP_046593311.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_015522339.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones"
XP_046602616.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I"
XP_046594682.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015520507.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway"
XP_046598720.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_015509417.1	11	Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-1912408;Reactome: R-HSA-6796648;Reactome: R-HSA-450341;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-5687128;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)"
XP_046593505.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046588422.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046589870.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015524031.2	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046591635.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046592386.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_046590465.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046598672.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_046589899.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046595780.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514134.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046598619.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_046597871.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015521565.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_015519276.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_046602482.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046595902.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015520703.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-9609736	"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"Gap junction assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors"
XP_046595843.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591986.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_015517233.1	10	Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201	"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis"
XP_046600132.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046587109.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_046597811.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015509456.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_046599561.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015516909.2	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046585753.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046591784.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_015509336.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046594729.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046586945.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015521495.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_015509494.1	13	MetaCyc: PWY-7112;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450"
XP_015520578.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512979.2	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046598436.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_046595444.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046589278.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015522561.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046589122.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015520053.2	4	Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_015523760.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015515164.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"HCMV Early Events";"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_015514262.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046588299.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015518122.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046585852.1	4	KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_046600671.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015511585.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_015522080.1	16	Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-983168	"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015510349.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_015520551.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046596032.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_015521948.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015523218.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046589769.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_015521488.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_015512185.2	7	MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221	"Sucrose biosynthesis II";"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)"
XP_015518527.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046598764.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046587065.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015512995.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046600959.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046595814.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046590997.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_015524794.2	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_046598223.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046598292.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046597698.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015510025.2	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_046586843.1	8	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046599424.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015521646.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_015509964.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015522759.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167238	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_046596138.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046601612.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_015518339.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_046598703.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_015522651.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015515429.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_046594732.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_015510129.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046593681.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046585745.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046597609.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_015518569.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015523700.2	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015515773.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-8012;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973	"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis"
XP_046586814.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015516423.2	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046586762.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis"
XP_015517076.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046601437.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_046587299.1	5	MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation"
XP_015521780.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_046601499.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_046586469.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046594044.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_046590484.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Gap junction assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs"
XP_015518936.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046586509.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046600676.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_015510232.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046600214.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_015524057.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_015509522.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046589038.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046598093.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046594647.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_046587723.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046589520.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046596624.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_015514584.2	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046586878.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046587167.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_046587932.1	6	Reactome: R-HSA-6785807;Reactome: R-HSA-2892245;Reactome: R-HSA-2892247;Reactome: R-HSA-3769402;Reactome: R-HSA-452723;Reactome: R-HSA-8986944	"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Deactivation of the beta-catenin transactivating complex";"Transcriptional regulation of pluripotent stem cells";"Transcriptional Regulation by MECP2"
XP_015512270.1	4	KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_046601557.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046590470.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046585980.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015517818.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046597416.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046586328.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163	"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_015519524.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_046597156.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046593816.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015518324.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046592200.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_015514166.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015519684.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046600134.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_015510729.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046591118.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046598862.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046601892.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046595779.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046588067.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416572	"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Sema4D induced cell migration and growth-cone collapse"
XP_015512922.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_015513509.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046592630.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046592131.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046589263.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586	"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence"
XP_046600098.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046598022.1	13	KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism"
XP_046588086.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046600548.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046585910.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_046592469.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046596330.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-9613829;Reactome: R-HSA-382556	"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Clathrin-mediated endocytosis";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport"
XP_015515898.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_046590479.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015509353.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015513475.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
XP_015512783.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046589457.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_046589181.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511122.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_015517232.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111463	"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs"
XP_015524228.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7417	"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046596345.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_015515705.2	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_015513397.2	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_015511549.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046589835.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046592582.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors"
XP_046595231.1	7	Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_015517208.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046588687.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046594230.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015517825.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015524617.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046588167.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_015515431.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046586595.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046602441.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015514970.2	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_015520251.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046598278.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015521150.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_015510456.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells"
XP_046594927.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046591426.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046599686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046598824.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_046587985.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015513501.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046598137.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046597245.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_015517609.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015516194.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046586525.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046589093.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015511105.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046590324.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_046586958.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_015520575.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_015511505.1	9	Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection"
XP_015512346.2	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046600384.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015516273.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046586040.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_046586380.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046592664.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-428543;Reactome: R-HSA-418885;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128	"Myogenesis";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling";"GPVI-mediated activation cascade";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling"
XP_046602341.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_046600392.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015524696.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046600266.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046594936.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046591220.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_015511111.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046602428.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046597880.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046592266.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015512750.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_015521664.2	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046587286.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_015519695.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_046592788.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_015524188.1	10	KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742	"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"RSK activation";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"
XP_015512247.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_046597727.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_015515788.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_046588686.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046602510.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015515089.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046587781.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_015512573.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_046588035.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015516198.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046600471.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015509744.2	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046593251.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_015515363.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046591889.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046597888.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046602402.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_015516161.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_015515488.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046587970.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046590259.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220	"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_046590714.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I"
XP_046592176.1	7	Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039	"Synthesis of PA";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule"
XP_046587053.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015517245.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046596919.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015525057.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_046589120.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015523977.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_046602339.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046597696.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015511231.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046586876.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015524064.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046592513.1	11	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046587495.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046589633.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_015513703.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis"
XP_046595939.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046596153.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015524707.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046599815.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015509610.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046602299.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046588423.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046595492.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism"
XP_046600782.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221	"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway"
XP_046587829.1	13	MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198	"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_015523023.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046598836.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-9609690	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events"
XP_015511747.2	8	Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_046597151.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015524828.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_015513640.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046598193.1	8	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_015520419.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046586724.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015510136.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015511386.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046588673.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046593680.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046596077.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046589761.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_015511919.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_015512593.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015519362.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015523329.2	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046601602.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_015521661.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046598221.1	5	Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_046598287.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015519040.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514106.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015520428.2	44	Reactome: R-HSA-3371453;Reactome: R-HSA-6802952;Reactome: R-HSA-879415;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-202670;Reactome: R-HSA-198753;Reactome: R-HSA-5668599;Reactome: R-HSA-2559582;Reactome: R-HSA-74749;Reactome: R-HSA-456926;Reactome: R-HSA-8939211;Reactome: R-HSA-8940973;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-170968;Reactome: R-HSA-8943724;Reactome: R-HSA-5673001;Reactome: R-HSA-881907;Reactome: R-HSA-9635465;Reactome: R-HSA-5654726;Reactome: R-HSA-982772;Reactome: R-HSA-9649948;Reactome: R-HSA-450341;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-6811558;Reactome: R-HSA-6802955;Reactome: R-HSA-112409;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5663213;Reactome: R-HSA-5674499;Reactome: R-HSA-2871796;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-5675221;Reactome: R-HSA-9634638;Reactome: R-HSA-6802948;Reactome: R-HSA-444257	"Regulation of HSF1-mediated heat shock response";"Signaling by BRAF and RAF fusions";"Advanced glycosylation endproduct receptor signaling";"Signal transduction by L1";"Regulation of the apoptosome activity";"ERKs are inactivated";"ERK/MAPK targets";"RHO GTPases Activate NADPH Oxidases";"Senescence-Associated Secretory Phenotype (SASP)";"Signal attenuation";"Thrombin signalling through proteinase activated receptors (PARs)";"ESR-mediated signaling";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"Frs2-mediated activation";"Regulation of PTEN gene transcription";"RAF/MAP kinase cascade";"Gastrin-CREB signalling pathway via PKC and MAPK";"Suppression of apoptosis";"Negative regulation of FGFR1 signaling";"Growth hormone receptor signaling";"Signaling downstream of RAS mutants";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF-independent MAPK1/3 activation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"mTOR signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Negative feedback regulation of MAPK pathway";"FCERI mediated MAPK activation";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of MAPK pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by high-kinase activity BRAF mutants";"RSK activation"
XP_015510108.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046594510.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_015523618.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015511366.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046602806.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015516813.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046598913.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015511179.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015510147.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015517093.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046594458.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_015512479.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046601032.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_015521457.2	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046586744.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015518923.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046596368.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_015519506.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_015523764.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046597128.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046597014.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046595410.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-4086398	"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ca2+ pathway"
XP_015510851.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_015509320.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_015524343.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation"
XP_015514914.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015513051.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015519858.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015512639.1	9	MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-7442	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis"
XP_015520919.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046600995.1	8	Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174	"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)"
XP_015514942.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7288	"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_015515634.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015518048.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex"
XP_046597728.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_015516691.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046591058.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_046602807.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046597383.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046589246.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_046596924.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015513738.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_046595225.1	15	MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40	"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_046587715.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046591217.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046597184.1	11	KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-3861	"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II"
XP_015524948.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III"
XP_015511717.2	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046590416.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046596878.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593065.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_015510080.2	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046592793.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600136.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015522457.2	13	MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392	"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II"
XP_015522479.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging"
XP_015517227.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046586442.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046599749.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046595383.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015523303.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015516694.1	10	KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9	"One carbon pool by folate";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes"
XP_046601127.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592841.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046587477.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_015510681.2	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046599920.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_015514741.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046586242.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_046596030.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046597445.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514991.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_046598693.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_015523774.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046594414.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015514713.1	11	Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_015513382.2	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_046589179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015511019.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_015512551.1	19	MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7383;MetaCyc: PWY-561	"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Methane metabolism";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_015514590.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport"
XP_046593801.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015516494.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5989;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971	"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_046590413.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046591353.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591059.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery"
XP_046586881.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_015520866.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_015512227.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586166.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_046599217.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_046601049.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046601707.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015509790.2	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_015523408.1	3	MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8	"L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation"
XP_046601688.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015515976.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015515554.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046597903.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015523354.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015514366.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046588890.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046601190.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015516071.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046588520.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015519085.1	7	MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3	"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate"
XP_046601916.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046596119.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_015512272.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033	"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones"
XP_015523287.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046588474.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015516147.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_046600669.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586829.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_015523778.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_015510919.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_015521284.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015515997.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046593765.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046593822.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015513192.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_046593611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015520885.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9617324	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_015515520.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046601768.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015514916.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046599915.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046588045.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046586908.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046595293.1	18	KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1	"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis"
XP_015517301.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_015511850.2	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_046588767.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046594080.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_015509716.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046589274.1	11	KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;MetaCyc: PWY-6608;MetaCyc: PWY-6999	"Purine metabolism";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Purine catabolism";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation III";"Theophylline degradation"
XP_015522700.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015524490.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_015519385.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593498.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046587906.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_015523022.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015517435.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046591315.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_015515297.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_015520867.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_015521536.2	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_046602265.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514132.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_015514917.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_015515805.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046600520.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046592048.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015512036.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015519045.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_046602276.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_046597949.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046598350.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015523036.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_015513749.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_046599155.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_015523009.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046598158.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
XP_015513272.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"MAP2K and MAPK activation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_046602230.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046594784.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_046598393.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_015511909.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015520883.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000	"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"RAF activation"
XP_046592230.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046597617.1	24	Reactome: R-HSA-5610785;Reactome: R-HSA-111931;Reactome: R-HSA-163358;Reactome: R-HSA-9010642;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-4420097;Reactome: R-HSA-163560;Reactome: R-HSA-9634600;Reactome: R-HSA-5621575;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-422356;Reactome: R-HSA-8963896;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-392517;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8853659;Reactome: R-HSA-381676;Reactome: R-HSA-164378	"GLI3 is processed to GLI3R by the proteasome";"PKA-mediated phosphorylation of CREB";"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"VEGFA-VEGFR2 Pathway";"Triglyceride catabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CD209 (DC-SIGN) signaling";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion";"HDL assembly";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Rap1 signalling";"DARPP-32 events";"mTOR signaling pathway";"RET signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling"
XP_015524459.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_046600217.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046593485.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis"
XP_015515960.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-381426	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046595052.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion"
XP_046601967.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_015509625.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_015517385.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015511201.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_046586346.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046587190.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046591214.1	7	KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-6351;MetaCyc: PWY-7625	"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Synthesis of PI";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_046590418.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046593125.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046591966.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046596970.1	20	MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_046585935.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015517672.1	6	KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-7395	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_046602513.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046595861.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015519004.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046585914.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440	"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network"
XP_015519166.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_046590636.1	4	Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50	"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism"
XP_015522288.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015515356.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046601778.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_015509845.2	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_015516369.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015523293.1	11	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"p38MAPK events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046601542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015514559.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046594812.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046595420.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015513698.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I"
XP_046591887.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_015514451.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046596254.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046601594.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015517887.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046592233.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046599523.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015523893.2	12	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_015513985.2	13	Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_015511730.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046586836.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046589316.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_015524799.2	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_046585979.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015511531.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046587475.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015522296.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046586601.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046599460.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription"
XP_046587711.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_015512627.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_015522611.1	12	Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826	"Growth hormone receptor signaling";"TNF signaling";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_015515418.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_046591164.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046588592.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_046601509.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015519547.2	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046592775.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_015510707.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046589484.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046597458.1	9	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046586826.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane"
XP_015514182.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange"
XP_015514872.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046594036.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_015516855.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015512519.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015523358.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046586361.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046590689.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_015513924.2	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Synthesis of PA"
XP_046591358.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_015517668.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_046596496.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046590033.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_046600740.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015512474.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046591045.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601024.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046591990.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046601764.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_015519159.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015524744.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046592061.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015519702.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046585884.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046590358.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015521936.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_015515416.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046601601.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_046596852.1	8	MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-73614	"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage"
XP_046595115.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_046589167.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046598952.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046602307.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046601284.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046598771.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046587676.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046594192.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015516866.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015524610.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015510464.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_046602798.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046599526.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046601931.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046588676.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046588900.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046599821.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046601800.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"ECM proteoglycans"
XP_046599240.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015518948.1	5	MetaCyc: PWY-7282;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_015512237.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046602432.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046595802.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015524255.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_015518038.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046591476.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_046592932.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015513096.2	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_015514443.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6	"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism"
XP_015518693.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
XP_046602502.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046593135.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046593504.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066	"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046592869.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597929.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600223.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046591812.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015517388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046595959.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-8937144	"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Aryl hydrocarbon receptor signalling"
XP_046588163.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_015522323.2	5	Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_015514196.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_046601545.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015513903.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046587689.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN"
XP_015522544.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046597533.1	29	Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046601733.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_015517693.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_015515186.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_046595291.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046589456.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046597810.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015515651.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015521456.2	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046599151.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_015521729.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046589981.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_046586610.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046594854.1	1	Reactome: R-HSA-419771	"Opsins"
XP_015510716.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_015515158.1	12	KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6122;Reactome: R-HSA-196780;MetaCyc: PWY-6613;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"One carbon pool by folate"
XP_046590680.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_046590906.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046594608.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_015515827.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046594834.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046593750.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046587188.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046586446.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046591310.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046589802.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046588778.1	13	Reactome: R-HSA-202433;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;MetaCyc: PWY-8052	"Generation of second messenger molecules";"DAP12 signaling";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis"
XP_046601957.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015514274.1	28	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-174437;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-68962	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HSF1 activation";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex"
XP_015524344.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046588457.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_015513728.2	31	MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWYG-321;MetaCyc: PWY-7746;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6799	"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)"
XP_015523318.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046595806.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015520329.1	15	Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75955	"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation"
XP_046586439.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046592512.1	11	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_015512604.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046586686.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015524058.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_046597800.1	13	MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7721;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7659	"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis"
XP_015510056.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_015518008.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_015521476.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015509440.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046594033.1	10	Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-163680	"Lipophagy";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity"
XP_015521585.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015519410.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-380320	"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes"
XP_046591487.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591457.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015515740.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046592969.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_046601031.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046588847.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism"
XP_015511276.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-1187	"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine"
XP_046590936.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_015509210.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174084	"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_046594102.1	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046597706.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046588848.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism"
XP_015520364.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_015513191.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168	"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)"
XP_046594297.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_015522794.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015513069.2	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_046593857.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046589182.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586806.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015522675.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046589326.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015510981.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015510495.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046595739.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046602054.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046586184.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_015511566.2	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_015509230.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015510783.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046600301.1	6	MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_046598140.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_046592604.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046593559.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9617324	"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_015518869.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_015513184.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_015514377.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046600460.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015522003.2	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_015514149.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046590075.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_015514486.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467	"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification"
XP_046590948.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-983168	"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015517200.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046586630.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046593119.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046587456.1	10	MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-2453864	"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism";"Amyloid fiber formation";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Retinoid cycle disease events"
XP_015519164.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046592395.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_046600294.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046601493.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_015510665.1	8	MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4	"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism"
XP_046589823.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046591048.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046594234.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046598818.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015512594.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046599241.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046598583.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015521903.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015514647.2	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_015515704.2	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046590045.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015520922.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046587329.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_015522836.1	9	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_046587285.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015512693.2	11	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_015515720.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046592310.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015518314.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046592425.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015510556.1	7	Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"RHO GTPases Activate Formins";"Degradation of DVL"
XP_046586569.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_015523515.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport"
XP_046600325.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046592038.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015513571.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_046592856.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_015517746.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40	"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism"
XP_046602053.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_015518440.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015524334.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_046594116.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015515873.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_015514469.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015524195.2	4	Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046592784.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046594669.1	12	MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9	"Stachyose degradation";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions"
XP_015514748.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_015514112.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015516500.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015525038.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_015510422.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046602465.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015512571.1	10	MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_015511379.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_015519815.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015513273.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_046600094.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_015511592.1	9	Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-112043	"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events"
XP_046598981.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_015512911.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015514146.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593054.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_015523499.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_015521663.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046599182.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046593304.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046592213.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046592175.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Synthesis of PA"
XP_015523428.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046586736.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046595418.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046599668.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism"
XP_015523199.1	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046588044.1	15	Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-9603505	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor"
XP_046590032.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_046592642.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046593999.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015517442.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046587905.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_015516579.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_046592852.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_015519627.2	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046589987.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_015522058.2	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046594580.1	11	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-5689880	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Ub-specific processing proteases"
XP_046589852.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046597199.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_015514090.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323	"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling"
XP_046602668.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_015520554.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046593627.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046601305.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015509471.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"HCMV Early Events";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_015516037.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_046592878.1	7	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling"
XP_015519739.2	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015517178.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
XP_046602405.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_015524748.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827	"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_015516580.1	7	KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
XP_046595002.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015519480.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046598237.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586470.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_015511829.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885	"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins"
XP_015509695.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_015514487.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9636467	"Insulin receptor recycling";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification"
XP_046585746.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_046598697.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_015516196.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_015509925.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_046599099.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015511504.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_046600742.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046598888.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;MetaCyc: PWY-6129	"N-Glycan biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis"
XP_046594261.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046596633.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_015510405.2	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_015510454.2	17	Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167238;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167243;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_046593725.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511657.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046596894.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_046594502.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_015522849.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046602755.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015519707.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897	"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Lipophagy";"TP53 Regulates Metabolic Genes"
XP_046597746.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046601780.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046590686.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_015516713.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046595388.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046585928.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-611105	"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport"
XP_046588093.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986	"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2"
XP_046602658.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_015510546.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597198.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_046593713.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046588766.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046587400.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586883.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_015514290.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046595386.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046586524.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046598541.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-918233;Reactome: R-HSA-9018519	"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression"
XP_015521389.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046601155.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046593233.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_015514471.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046594219.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_015514151.1	11	Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism"
XP_046594811.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046597006.1	9	Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-167290	"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation"
XP_046598396.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015516509.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046597601.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_015523537.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046593829.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046598220.1	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046601137.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046590031.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_015511130.1	27	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-9010553;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-167200;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-167152;Reactome: R-HSA-159231;Reactome: R-HSA-674695;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-73856;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-975956;Reactome: R-HSA-159230	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Regulation of expression of SLITs and ROBOs";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Pre-transcription Events";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA Polymerase II Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA"
XP_015512090.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046589632.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046595705.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400	"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER"
XP_046594560.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015512368.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015516391.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046595604.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_015509637.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015521923.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046600509.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015514737.2	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046595493.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_046600574.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015512602.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046593134.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046592968.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_015519061.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_015519261.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015522089.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046597307.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015516305.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597831.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection"
XP_046585948.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_046596986.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046587432.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046598765.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015511605.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046589546.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046599599.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046602303.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015520474.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-2467813	"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids"
XP_015514272.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015518877.2	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_015517085.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046595804.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593650.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_015521199.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015522254.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046587685.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation"
XP_046600387.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046598891.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046598575.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015515343.2	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_046599883.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046587928.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_015511104.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046599280.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046597038.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046588777.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2	"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine metabolism"
XP_015518074.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_046593854.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015520247.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046602705.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046595850.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015517243.2	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_015513483.1	7	MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis"
XP_046594176.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046586668.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046596136.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046593509.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046598433.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046596705.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015510110.2	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046589528.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046599176.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015523161.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764	"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling"
XP_046593164.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046600900.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046592956.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_015510540.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046590697.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling"
XP_046585870.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015512242.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046588367.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597917.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_015509949.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-5695	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Inosine 5'-phosphate degradation"
XP_015520447.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
XP_046591816.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)"
XP_015510663.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4	"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine salvage";"Neutrophil degranulation";"Purine metabolism"
XP_015514468.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046589232.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046594419.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_046595101.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_015520657.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015513523.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046589762.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_015522104.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_046602185.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_015517917.2	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_015509775.1	7	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis"
XP_015516499.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_015517407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046594465.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015514871.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046590743.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-74217	"Purine metabolism";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage";"Purine salvage"
XP_015513548.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_015512666.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_015518945.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_015515061.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_015510064.1	13	Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_015515417.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046598042.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015523116.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015510669.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046594191.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046588394.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015509594.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592774.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_015521188.2	10	KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_015517255.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015519145.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_046593320.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_046589543.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_015524743.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046599033.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046591964.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_015511524.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046585756.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_015517605.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015510259.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_015518021.2	9	MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation"
XP_046594781.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046600225.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_015511124.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_015517602.1	12	Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2122948	"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_015520577.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046599679.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015511209.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015517651.2	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046593840.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015515800.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015521814.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015513631.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046600948.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_015512727.2	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_015511668.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046590774.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_015522371.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046597287.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046593248.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046602243.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046595040.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046591480.1	16	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs"
XP_015522065.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015520023.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_015520899.2	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_046588688.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015515397.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015509204.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046590184.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046588179.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046598633.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046598768.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046599158.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046601785.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015516508.2	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046591514.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_015524675.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046588404.1	4	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046595858.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_015514049.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046585692.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_015524894.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_015515087.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593515.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046587787.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_015514045.2	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046596201.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_015520339.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015519142.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_015519535.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046593763.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046595419.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046587681.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_015515910.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046596687.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046600206.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046591163.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046600293.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_015521999.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046594909.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046598982.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046594298.1	8	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_046586419.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588486.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046600711.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046586952.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333	"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_015509814.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046591950.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_015522326.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144	"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1"
XP_015510480.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_046585758.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046598138.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046587321.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046598694.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_046600400.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-354192;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"Integrin signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Downstream TCR signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"Human cytomegalovirus infection";"RSK activation";"Thermogenesis";"Activation of AKT2";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection"
XP_015523892.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046586224.1	7	MetaCyc: PWY-7219;MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234	"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III"
XP_046591291.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_015524342.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy"
XP_015522926.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046594259.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046589118.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046594734.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015512031.1	34	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs"
XP_015512236.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_015515896.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046597280.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046594125.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway"
XP_046591490.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_015512831.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_046601339.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015510240.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_015523748.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_046595144.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015521361.1	6	MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664	"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_015516849.2	7	Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_015519400.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_046599097.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015515342.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046601734.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046592142.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046598915.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_046600773.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_046591923.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015515608.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015515127.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_015520136.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_046589019.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046591265.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046600775.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_015512608.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046598558.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_015514661.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046601536.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015521463.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_046591888.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046598039.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015513359.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046590778.1	7	Reactome: R-HSA-1474151;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate"
XP_046592670.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015522857.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046586305.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_015510234.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046596807.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046587325.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis"
XP_015518880.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_015524033.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046602436.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_015511792.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046590424.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_015511795.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046587121.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046599570.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046586560.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_015509457.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_015516826.2	8	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_046586039.1	14	MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_015512539.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis"
XP_015510115.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_015511818.2	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_015522596.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_046588090.1	11	Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631	"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility"
XP_046594002.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015522257.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046598769.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046590415.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_015514601.1	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9	"Galactose metabolism";"Sucrose biosynthesis II";"Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_015522638.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium"
XP_046598253.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_015516867.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015522916.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046586845.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046598151.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046600539.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046595869.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015519384.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015519427.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046602737.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046586019.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015511778.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046592163.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046589257.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015512042.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_015509596.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046593120.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046599644.1	5	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_015517052.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046590055.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046587306.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046596207.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046587915.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_015523147.1	11	MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4	"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_046596038.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015515891.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046586703.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_046602732.1	18	Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788	"Acyl chain remodelling of PG";"Ether lipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC"
XP_015515379.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046601520.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_015521945.1	10	Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004	"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity"
XP_015509235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015513522.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_015514708.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046600513.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046601302.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046594038.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046602149.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514813.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion"
XP_046600389.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015523192.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046598380.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_015513139.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046591663.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046600744.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015516383.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046589230.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_015521302.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_015523766.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046599067.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046600236.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_015516197.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046593518.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production"
XP_046594015.1	17	MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-5532;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-74259	"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Nucleoside and nucleotide degradation (archaea)";"Purine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage III";"Purine catabolism"
XP_046594081.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046599913.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046596180.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_015522551.2	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046592776.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_015522876.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015525041.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046592429.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015519798.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_046596004.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_046596116.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015519982.2	3	KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560;Reactome: R-HSA-5666185	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"RHO GTPases Activate Rhotekin and Rhophilins"
XP_015520752.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046588866.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046587815.1	13	MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates"
XP_046590763.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046591997.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046585881.1	9	MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_015515652.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015516498.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046592046.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015523550.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-5617472;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-72086	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"mRNA Capping"
XP_046592487.1	17	KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789	"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Fatty acid biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_015510301.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_015518711.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046594279.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_046601119.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_015520472.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262	"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_015516673.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015512592.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046587678.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_015524567.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015520613.2	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_046588139.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015511184.1	19	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Protein methylation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015518281.1	14	Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Macroautophagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Intraflagellar transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046597042.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046599402.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111464	"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_015517081.2	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation"
XP_046597702.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015519283.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_015520874.2	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046602030.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_046599985.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_046594853.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592153.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046592671.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046597484.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046590110.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins"
XP_046594866.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_046592851.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_015509400.2	13	KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation"
XP_046597124.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046596193.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_015515244.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_015518334.2	10	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05170+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"mTOR signaling pathway";"HATs acetylate histones";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Ub-specific processing proteases";"Human immunodeficiency virus 1 infection"
XP_015512898.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_015512540.2	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_015524461.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation"
XP_046599524.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015512997.2	9	Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_046587799.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_046599082.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046597149.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015515466.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046585868.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_046592931.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-110328	"B-WICH complex positively regulates rRNA expression";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Meiotic synapsis";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Amyloid fiber formation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046588366.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015511013.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046600550.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015521204.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_015517417.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046591162.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015524330.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_015518307.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597639.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046598008.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_046594996.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046591355.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_046592875.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046585757.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046585754.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_046586047.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_015516081.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II"
XP_015515412.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Human immunodeficiency virus 1 infection";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_015519768.2	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046601878.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015515081.2	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046600163.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046591255.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593502.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046588776.1	6	MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819	"Thiamine salvage III";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism"
XP_015512207.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046593806.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348	"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex"
XP_046586522.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_015519787.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046589850.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046591203.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_015522019.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046591664.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591269.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_015515695.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_046587794.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046592058.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015522209.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046601883.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046594910.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046602222.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046601876.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015510700.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046599746.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015517294.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_015521623.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592514.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_015513997.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046586670.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046592441.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015517446.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046595142.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046591937.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015517026.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015516621.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Other glycan degradation"
XP_015516240.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015512981.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001	"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_046595891.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046598348.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046597570.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046590354.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015509335.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_015518280.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation"
XP_015524196.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_046598533.1	12	MetaCyc: PWY-5871;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978;MetaCyc: PWY-5872;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_046600299.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_015512432.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046596923.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015514730.2	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_046587102.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015512198.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_046591907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046594878.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry"
XP_015521534.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015511986.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015509315.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046587710.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_015510873.2	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046602403.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046586661.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046589792.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015519583.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046590573.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_015524046.2	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_015517230.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046593836.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015518200.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_046596296.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015518129.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046591271.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046587912.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046593825.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015514560.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions"
XP_015520570.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_046594754.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511853.2	8	Reactome: R-HSA-191273;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_015520811.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015519861.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_015510169.2	10	MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-4661	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_015512124.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_015520696.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_015512628.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism"
XP_046593275.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015518493.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_046602706.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_015513204.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174178	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Interleukin-1 signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_046599678.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015510173.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046600861.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046600706.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046587702.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046597767.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-mediated anterograde transport"
XP_046591715.1	7	KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00650+4.1.3.4	"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Butanoate metabolism"
XP_046588317.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046596820.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_015517172.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015519579.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015521464.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_015514811.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046589988.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_046596998.1	3	Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015518806.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046601428.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_046591307.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015510972.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046591956.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046589826.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046585751.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors"
XP_015519103.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_015509160.1	10	KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1	"Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_046592203.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_015513292.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015509267.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015515207.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046595351.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015520649.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046593516.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_015511594.1	37	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-2132295;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-983170;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-9639288;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-204005;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9609690	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"MHC class II antigen presentation";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Amino acids regulate mTORC1";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"COPII-mediated vesicle transport";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events"
XP_046602483.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_015520459.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade"
XP_015522342.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases"
XP_015516919.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046593982.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_046593215.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046594028.1	7	MetaCyc: PWY-7238;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25	"Sucrose biosynthesis II";"Starch degradation V";"Neutrophil degranulation";"Starch degradation II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism"
XP_046591790.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046598815.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015524002.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046589979.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046600441.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046587478.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_015509480.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_015522090.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015518888.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046597758.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046596159.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046589631.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046589385.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_015516996.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046602804.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046594758.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511089.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_046589689.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_015523356.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_046588452.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591170.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015518881.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015519300.2	31	MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-8047;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-7663	"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)"
XP_046593430.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046587237.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046597246.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357	"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1"
XP_046602224.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_046592110.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_015523503.2	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046591895.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015518653.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046602077.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015514174.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells"
XP_046593009.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046594422.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046593826.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046596262.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046591836.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_015520571.2	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046590095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046590061.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015510272.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015524101.2	4	KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247	"Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids"
XP_046590117.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046594294.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_046587327.1	5	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_046586838.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046597798.1	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-5122	"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis"
XP_046588088.1	25	Reactome: R-HSA-8941332;Reactome: R-HSA-8931987;Reactome: R-HSA-8935964;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242;Reactome: R-HSA-8941284;Reactome: R-HSA-8877330;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8939246;Reactome: R-HSA-8941326;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-8949275	"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates chondrocyte maturation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates bone development";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 Regulates Immune Response and Cell Migration"
XP_046597510.1	10	KEGG: 05170+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"T cell receptor signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TNFR1 signaling";"mTOR signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_046587236.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046591967.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046602364.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_015515432.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_015511331.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046594988.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046594345.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015512838.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015520140.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_015512406.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015518804.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015515762.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_046598618.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585	"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence"
XP_046602020.1	12	MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1	"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism"
XP_046586441.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046600678.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_015516788.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046592787.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046595856.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046598590.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_015509607.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015512176.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_046598951.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_046595678.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046586289.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy"
XP_015509523.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046599226.1	7	KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism"
XP_046600799.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015525036.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015512360.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015515086.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591385.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_046598777.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046591387.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046596176.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700	"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_046591007.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_015524050.2	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046586330.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_015518108.2	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046589248.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046601314.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046596657.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046598856.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046594948.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)"
XP_046589529.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046597485.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046593772.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015524753.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046593069.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046586916.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046602309.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046598857.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046598154.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_046600537.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046595042.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_015510709.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046598232.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046600783.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221	"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway"
XP_015524749.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Neddylation"
XP_015514721.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046596485.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015517364.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_046597015.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046591882.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046594360.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-429947	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA"
XP_046587095.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046591218.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046594720.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046586578.1	7	MetaCyc: PWY-6969;MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7118;MetaCyc: PWY-7295;KEGG: 00630+2.3.3.9	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"D-xylose degradation IV";"Chitin degradation to ethanol";"L-arabinose degradation IV";"Glyoxylate and dicarboxylate metabolism"
XP_046599286.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_015518018.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_015523705.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046590185.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015524586.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046592733.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046602083.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_015523182.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046598623.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897	"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes"
XP_046602584.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_015516165.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015509735.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015517685.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_015520872.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046598698.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_015519831.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046590513.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015516761.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress"
XP_015521532.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046592531.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046594514.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046600405.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_046592785.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_015514392.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046595962.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_015516707.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015515729.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_046595372.1	18	Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-1221632;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;Reactome: R-HSA-3108214;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Meiotic synapsis";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination"
XP_046597299.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046588215.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046588677.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046594016.1	17	MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-7179-1;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695	"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Purine catabolism";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation II";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation"
XP_015510706.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015509846.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015514821.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046592521.1	33	Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-112382	"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_046599463.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-210744	"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_015509395.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_046589445.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015523145.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046589343.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015519163.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_046596559.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046596891.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015514181.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046599780.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046596219.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167238	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_015522993.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015510616.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_046594078.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_046592923.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046596631.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_015510186.2	19	Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497	"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"LDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL remodeling";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class H Receptors"
XP_015513619.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015523517.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-mediated anterograde transport"
XP_015516453.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_046597985.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_015517901.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_046585941.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015520502.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046598707.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046597447.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046596650.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling"
XP_015514969.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046587494.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046602003.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046601637.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_015518259.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046585732.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_015522375.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046601782.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046590688.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015521574.2	8	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication"
XP_015524227.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046593708.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046586094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015522419.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation"
XP_046590796.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint"
XP_015520444.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015517593.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_015513338.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-418885	"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"EGFR downregulation";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"Myogenesis";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling"
XP_015510347.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_015523561.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046597530.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-1268020	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial protein import"
XP_015522808.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046592314.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015509788.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015515851.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_015524135.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046597141.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015511211.2	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_015512033.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015523279.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_015509724.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046590577.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046592725.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046589037.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046587267.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_015517183.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046585942.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046602438.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_046592113.1	7	Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_015523058.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046587093.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046591508.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046588861.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046601541.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046595953.1	11	Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection"
XP_015524146.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015522434.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046586816.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046601827.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592927.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_015512895.1	16	Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-114604	"Interleukin-7 signaling";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RET signaling";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"GPVI-mediated activation cascade"
XP_015514208.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_046597340.1	8	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_015520886.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-111932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB"
XP_046600216.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_015514046.2	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_015517664.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046587528.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046602440.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015514851.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015524627.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015518212.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015523480.2	8	MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481	"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate"
XP_046596978.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_015510975.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_015509825.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602298.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046586163.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_046597931.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015517661.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015510854.2	27	Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333	"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046591224.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046599761.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015523030.2	4	MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072	"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Alanine racemization"
XP_015522769.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_046601233.1	4	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_015510636.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046599854.1	6	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_046601084.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046596323.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399	"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Clathrin-mediated endocytosis";"Aggrephagy"
XP_015520678.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_046602183.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046599038.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046596178.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity"
XP_046602242.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015521252.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015513508.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015518578.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_015518033.1	11	Reactome: R-HSA-1660517;MetaCyc: PWY-6352;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_046591803.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046598276.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046596617.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015521666.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046587520.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046601793.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046599370.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046586449.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046598867.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046586248.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_046591797.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
XP_046587910.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_015512694.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_046587445.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_046599028.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015518892.1	42	Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-977225;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-2559586;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-5334118;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-5693565	"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"DNA methylation";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_015512630.1	56	Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424	"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling"
XP_015516693.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_015511400.1	16	Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-437239	"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Recycling pathway of L1"
XP_015517944.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046602472.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015522356.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_046599114.1	7	KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_015522053.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046588846.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046594989.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046595567.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_015524253.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_046599972.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015520448.1	23	Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418217	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G-protein activation";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta"
XP_015522154.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015509723.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046601953.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015510429.2	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_046596486.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046597070.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015512709.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046599179.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046600140.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046596465.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015522971.2	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015511621.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_046588573.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046601842.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046593601.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046591068.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015515133.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75955	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation"
XP_015516760.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_015512152.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046598552.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589092.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046596268.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597047.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015514453.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046593312.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_046586571.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_046600228.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046602278.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046592446.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046591259.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046602245.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015511195.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_015514621.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_046590030.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_046599423.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046588162.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_046588252.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046598417.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015516491.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015520480.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_015510236.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_015519532.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015520592.2	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046591995.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046589436.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015515323.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046591699.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046593830.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046588424.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046597509.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_015517058.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046587406.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938	"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)"
XP_015520454.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046591892.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015516301.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015521422.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046592119.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046593510.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046593619.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046587073.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046592669.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015523813.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015524424.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046600462.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046592656.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046593580.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants"
XP_015519822.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_015515399.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046591390.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_015511658.2	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_015524745.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_015515355.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015523464.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046597946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593151.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015513491.2	29	Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6781823	"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex"
XP_015524145.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046598149.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046588460.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015516910.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046586943.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015515901.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_046587675.1	1	Reactome: R-HSA-419771	"Opsins"
XP_015515865.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046591770.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046601611.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046591293.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046592848.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015519639.2	6	Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402	"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046596627.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_046595976.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-3214858	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines"
XP_015519541.2	4	Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581	"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis"
XP_015514707.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015518393.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_015519417.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046602439.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046596320.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880	"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Aggrephagy";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases"
XP_015517755.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015509913.2	10	MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism"
XP_015523803.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015523673.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_015524642.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_046601665.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015518719.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015519379.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046591705.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015519588.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015514539.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167238	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_015515139.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046589920.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046596133.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-5656121	"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI"
XP_046592128.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046599537.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046593416.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046588759.1	17	Reactome: R-HSA-113501;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-69656;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-9616222;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-6804114	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_046586882.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_015514959.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511616.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046587984.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046593250.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport"
XP_015513550.2	19	Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828	"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"LDL remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"LDL clearance";"Chylomicron clearance";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis"
XP_015518723.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046595857.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_015520013.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046587060.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046598811.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015515138.2	4	KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046590410.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_015518536.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_015523706.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046595252.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046587537.1	14	MetaCyc: PWY-3661;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497	"Glycine betaine degradation I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"One carbon pool by folate";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism";"Folate polyglutamylation";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)"
XP_046599628.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_046602712.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_046585903.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046599820.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015518449.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015514852.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015517607.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046593633.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015510404.2	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_015512244.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_015523756.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015523183.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015509632.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046595135.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015511401.1	16	Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-437239	"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Recycling pathway of L1"
XP_046598677.1	8	MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-6791462	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P"
XP_046597611.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_015513333.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_046586452.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015520082.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592027.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046599633.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_046586217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046596472.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046590024.1	14	MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II"
XP_015510724.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015517116.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511798.1	7	MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;MetaCyc: PWY-6470;MetaCyc: PWY-6471;Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_015518155.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_015514058.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046586959.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046601700.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046598378.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046597213.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015513742.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_046599743.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_015517702.2	6	MetaCyc: PWY-922;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33	"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_046597902.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046592837.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046598411.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_015513724.1	7	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis"
XP_015513575.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046587916.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046592168.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592900.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-73728;Reactome: R-HSA-2299718;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379	"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"RNA Polymerase I Promoter Opening";"Condensation of Prophase Chromosomes";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events"
XP_046599822.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046597957.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046601188.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015523971.2	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046589978.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046595643.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_015522300.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046597224.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015521261.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015510031.1	5	Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism"
XP_015519696.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046598353.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015522911.1	5	KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
XP_046592871.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142	"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins"
XP_046597004.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_015522831.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_046599748.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_015519313.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_015516190.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015511860.2	3	MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_046592700.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_015520218.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_015515633.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046589482.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_015521323.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046586302.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching"
XP_046599064.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_015517733.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_015514021.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015510345.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_046593833.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015524429.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_015511612.2	5	MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine metabolism"
XP_046598855.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_015518967.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism"
XP_046601702.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046592668.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-418885	"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"EGFR downregulation";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"Myogenesis";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling"
XP_015515986.2	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_015518022.2	9	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_046592533.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046587443.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation"
XP_046596943.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_015518748.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway"
XP_046587473.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046602346.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_015525018.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046586513.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015510377.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015512962.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_015521351.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046596645.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events"
XP_046599014.1	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_015511727.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046590717.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046598500.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015521008.2	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046595633.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_046597791.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046597607.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046599666.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation"
XP_046597771.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015523941.2	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046599747.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046586386.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046599911.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_046599212.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046595443.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_046600344.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015524904.2	5	MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;Reactome: R-HSA-71336;MetaCyc: PWY-8060	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I"
XP_046594509.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_015510241.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046597640.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_046599285.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_046601525.1	6	Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Defective GALT can cause Galactosemia";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism"
XP_046594238.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015520055.2	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046595000.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046587041.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_015521807.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_015524182.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046598143.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_015518887.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046595950.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302	"Human immunodeficiency virus 1 infection";"p38MAPK events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation"
XP_046593777.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015516258.2	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_046594415.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_046595629.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015523940.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046588572.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046586475.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015523594.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046591264.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046599403.1	5	Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111469	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response"
XP_046598053.1	13	Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_046599473.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046588996.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596558.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046601697.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Neutrophil degranulation"
XP_015524892.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046593685.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046601071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015524494.1	7	KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4	"Geraniol degradation";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies"
XP_015523790.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046587476.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046594503.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_015510699.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591135.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_015517575.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_015518091.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046593520.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046589080.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046602814.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015522593.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638	"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins"
XP_046598296.1	29	Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_046592122.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015523522.2	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_015519172.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046597577.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_046586776.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs"
XP_046595140.1	6	Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-6309	"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_046597325.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046601747.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_015516596.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046593846.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015510024.2	5	Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536	"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_046598863.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046588050.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_046585865.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_015519043.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046593450.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692	"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity"
XP_046598279.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015521653.2	5	Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_046602114.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_046602406.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_015510819.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046599750.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046596647.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (i) signalling events"
XP_015520178.1	18	KEGG: 00720+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7383	"Carbon fixation pathways in prokaryotes";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Methane metabolism";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_015514740.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015520025.2	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_015518800.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046600133.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046598271.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046592229.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046592315.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046600423.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046596646.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events"
XP_015514027.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint"
XP_046587484.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_015511644.1	6	KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017	"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046597983.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_046595808.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046586827.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_015512910.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015523696.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_015513721.2	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex"
XP_046600667.1	12	KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-6932;Reactome: R-HSA-174362;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340	"Purine metabolism";"Sulfite oxidation III";"Selenate reduction";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Sulfur metabolism";"Purine metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfate activation for sulfonation"
XP_046589264.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632	"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis"
XP_046595778.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046585976.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046594821.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046599275.1	10	Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664	"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation"
XP_046599325.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046592376.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-2467813	"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids"
XP_046602151.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586615.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046596266.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015513453.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-72764	"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination"
XP_015523308.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015516832.1	7	MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Synthesis of GDP-mannose"
XP_046589308.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_015522157.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_015517669.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046590307.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046588212.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046600860.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015513568.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015509263.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_015515498.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046602515.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_015517534.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046595579.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046599631.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells"
XP_046592958.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046591425.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015512518.2	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_015515857.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511578.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046597676.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_015512085.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_015518712.2	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_015514588.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015521034.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_015515908.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046595694.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_015513298.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015514020.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046602239.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046587480.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046591791.1	9	Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324	"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046597308.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015523006.1	13	MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_015522195.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562	"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"Interleukin-1 signaling";"Hedgehog 'on' state";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)"
XP_015521531.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046601242.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046589846.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046597327.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275	"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation"
XP_046598581.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046593684.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_015517554.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_015517537.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_015514273.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015516034.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046599790.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046596413.1	12	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5655302;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Signaling by FGFR1 in disease";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"mTOR signaling pathway"
XP_015511165.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_015518626.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12	"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms"
XP_015511666.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046588568.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046593788.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015516294.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_046588674.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_015511416.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046592565.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_015511430.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs"
XP_046600406.1	5	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_015512412.2	5	Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade"
XP_015511319.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046602295.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597872.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_015521916.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593432.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_046593303.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046588321.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046596167.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046587586.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_015518531.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_015522392.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015517920.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015518346.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_046587914.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046588237.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046595888.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-7442	"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis"
XP_015521686.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_015519800.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_015524885.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046592537.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046596206.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015520309.2	8	Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68689	"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex"
XP_015515168.2	7	KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5686	"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"UMP biosynthesis I"
XP_046591507.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046601448.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_015512790.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046600267.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046591205.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852	"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy"
XP_046598277.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046592028.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046597801.1	13	MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-6859	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis"
XP_046587084.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046593929.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_015514667.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_046588218.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_015524599.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_015521685.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046595575.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015515404.2	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046597443.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_015517832.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015520265.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine metabolism"
XP_015520774.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015510856.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594576.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046593059.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_015524718.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046592118.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015523762.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046587098.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015524059.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_046587023.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046602708.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_046590795.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015513973.1	30	Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-8941332;Reactome: R-HSA-9614399;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-5218920;Reactome: R-HSA-6804758;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-1358803;Reactome: R-HSA-69656;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-199418;Reactome: R-HSA-9634638;Reactome: R-HSA-8948751;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-198693;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757	"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"RUNX2 regulates genes involved in cell migration";"Regulation of localization of FOXO transcription factors";"Human papillomavirus infection";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Activity through Acetylation";"Relaxin signaling pathway";"CTLA4 inhibitory signaling";"Downregulation of ERBB2:ERBB3 signaling";"Cyclin A:Cdk2-associated events at S phase entry";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of PTEN stability and activity";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"Thermogenesis";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the nucleus";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation"
XP_015517667.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046593984.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015521172.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_046589146.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation"
XP_015510187.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046589242.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046593853.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046586777.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_046598746.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015524690.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015519646.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_015515902.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_046598629.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_015510185.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015512487.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046586705.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_046595238.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597841.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_015518002.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015512144.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015522558.2	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046596545.1	3	Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741	"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046602297.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046595429.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046595791.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046595432.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046599101.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015510772.1	17	KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168	"Pyruvate metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Glyoxylate assimilation";"Carnitine metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)"
XP_046586766.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046593517.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-427413	"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression"
XP_046594124.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046589472.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015514002.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15	"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_015524602.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046601706.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_015510455.1	11	Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-72163;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046594777.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_015521304.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_015516021.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_015514918.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046586702.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046591309.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_015514207.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11	"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
XP_015521909.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046588131.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592953.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_046594689.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress"
XP_015519341.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597286.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046587505.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_046589692.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_015524167.2	4	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_015512598.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046598854.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_015513153.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_015521620.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046596000.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_015513958.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_015514201.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046592047.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046598534.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-2142789	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_015524317.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_015519423.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_015520671.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046600680.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046600221.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_015512475.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046602305.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046592794.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046597840.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046590278.1	31	MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5989;MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971	"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_046588066.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046602017.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046594256.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_015525115.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046599856.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-611105	"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport"
XP_046599465.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-210744	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_046592559.1	6	MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_046597918.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015516589.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_015521902.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015514576.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046594676.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_015515225.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015512715.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046589346.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_015517742.2	6	KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010	"Vitamin B6 metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_046598578.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046601151.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_015513919.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518503.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046586378.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015515149.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046592065.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046590010.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046587099.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046591222.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_015515938.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046593848.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_046602534.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046594342.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046587538.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015521126.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015518943.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046595952.1	11	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events"
XP_015519737.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046589759.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046587091.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_015510876.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015514662.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046596691.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_015524254.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_015510679.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_046587116.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046591123.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress"
XP_015510048.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046598977.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_015511975.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046588862.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015521786.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015517975.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015523297.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015511064.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046594270.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_046590494.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015518140.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015523698.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_015510807.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046592170.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015514091.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046588192.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015509245.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046602330.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046590411.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_015524341.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_015518934.1	17	MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-74259;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1	"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine salvage";"Purine catabolism";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II"
XP_046590444.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
XP_015518169.2	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_015511516.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046594401.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_015522280.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046593309.1	6	Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_046591670.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046597285.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_046588160.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_046589513.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015511952.1	1	Reactome: R-HSA-419771	"Opsins"
XP_015511892.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015523024.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015517513.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046595941.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046594852.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046598036.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046593790.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5358752	"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated"
XP_046592708.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_046586844.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway"
XP_015510954.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_046591750.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_046600998.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_046590580.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046595803.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588251.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511059.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046585946.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_015524497.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_046595574.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597154.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015513306.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046593018.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_015519036.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046592676.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046589081.1	14	MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589	"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_046587013.1	2	Reactome: R-HSA-167826;Reactome: R-HSA-167827	"The fatty acid cycling model";"The proton buffering model"
XP_046599755.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_046589449.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046588043.1	15	Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046586800.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046596131.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-110312	"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1"
XP_015518214.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046594340.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015518722.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_015510119.2	7	MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-6610	"Glyphosate degradation III";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage II";"Adenine salvage"
XP_015524706.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046593831.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046600746.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046586754.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3"
XP_046595859.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046595437.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046601771.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015521030.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046600330.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046592631.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046587540.1	16	Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-437239	"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Recycling pathway of L1"
XP_015521319.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588292.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_046600031.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046599777.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046588389.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015510770.1	17	Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6679	"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Carnitine metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis"
XP_046588899.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015517379.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046597254.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_015520676.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046589245.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_015509879.2	7	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-6596	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I"
XP_046598924.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_046586069.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4	"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Synthesis of PE";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Ether lipid metabolism";"Synthesis of PC";"Glycerophospholipid metabolism"
XP_046594797.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046593525.1	19	MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5172;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Neutrophil degranulation"
XP_046594071.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_015514446.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015516125.2	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046590794.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046591767.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015517606.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046596370.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046598793.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046599567.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046596585.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046593622.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015509740.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-8866654;Reactome: R-HSA-110314	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex"
XP_015509633.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046590925.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_015515140.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015512103.2	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015513201.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046602180.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046594037.1	5	Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_015523018.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015516015.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_015509215.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_015511722.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_046596412.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015520834.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_015511060.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock"
XP_046595742.1	33	Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_015521124.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015519351.2	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_015521533.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514048.2	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism"
XP_046596226.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37	"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism"
XP_046596879.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015521391.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015519823.2	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_046601535.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015517213.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_015522776.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046587539.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046600606.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_046589488.1	31	KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7746;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049	"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis"
XP_015522385.2	2	Reactome: R-HSA-5656169;Reactome: R-HSA-9033241	"Termination of translesion DNA synthesis";"Peroxisomal protein import"
XP_046586216.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy"
XP_015510100.2	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_015516408.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046601350.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046594129.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046591578.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046594646.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046597474.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_015516920.2	1	Reactome: R-HSA-419771	"Opsins"
XP_046591361.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046599373.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_015523456.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046594774.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2644606	"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_015515447.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_046589244.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_046590534.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015522654.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_046597701.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046595250.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046587428.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015517781.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015523763.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046598576.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586072.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046600670.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015520825.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_046585905.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046600958.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046590429.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046588325.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015509660.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_015516057.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046597049.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046601750.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046586720.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046586071.1	14	KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-4419969	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PC";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina"
XP_015510407.1	4	KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_046588133.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589948.1	10	MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)"
XP_046596866.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046593143.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_015521718.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015514035.2	10	Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_046601773.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046599648.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046585912.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation"
XP_046599413.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046596967.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation"
XP_046585780.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_046593007.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015518631.2	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_015518187.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512909.2	13	Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation"
XP_015519058.2	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046601621.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827	"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of DVL";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex"
XP_046589271.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_015512849.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_015514983.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes"
XP_046594501.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046596134.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942	"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Polymerase switching";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)"
XP_046590902.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2	"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046586822.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-445989	"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_046597526.1	4	MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_015514863.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_015522828.2	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046596620.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046596867.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046587141.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015513309.2	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_046598712.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_015517384.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046589707.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_015512903.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015521194.1	8	KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046599315.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events"
XP_015510440.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015524887.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_015513607.1	7	MetaCyc: PWY-7295;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-7854	"L-arabinose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_015509753.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_015510223.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046599740.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_015511210.2	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_046587987.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015513236.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_046595030.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046589110.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046590420.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046587931.1	6	Reactome: R-HSA-8986944;Reactome: R-HSA-452723;Reactome: R-HSA-3769402;Reactome: R-HSA-6785807;Reactome: R-HSA-2892247;Reactome: R-HSA-2892245	"Transcriptional Regulation by MECP2";"Transcriptional regulation of pluripotent stem cells";"Deactivation of the beta-catenin transactivating complex";"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"
XP_046598136.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_015523771.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_015522204.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_015517160.2	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA"
XP_015512268.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_046588780.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_015523907.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292	"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome"
XP_046595143.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046594077.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_015524364.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046601279.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801	"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_046586379.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015514464.1	13	MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)"
XP_046596562.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046591921.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015515027.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015512501.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015517695.2	13	KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;Reactome: R-HSA-74259;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7206	"Starch and sucrose metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_015515945.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_015522826.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046590335.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046587907.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046593724.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656169	"Translesion synthesis by REV1";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis"
XP_046593068.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_046594105.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_015520143.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_015518213.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046593667.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046601521.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_015519853.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586599.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_015516520.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_015510606.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_015516448.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046593839.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046589918.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015514527.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes"
XP_015524997.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-3781	"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)"
XP_015514237.2	7	MetaCyc: PWY-6692;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.2;MetaCyc: PWY-5083;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-4302	"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)"
XP_046595937.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046595290.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_015517441.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046596920.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046602723.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046601920.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046588194.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015517925.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015514842.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_046589487.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_015520108.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11	"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism"
XP_015509243.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_015510237.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_015509277.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046595674.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion"
XP_015522957.2	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis"
XP_015515078.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046586606.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_046599795.1	8	KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1	"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis"
XP_015516554.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046588669.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_015512407.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015511513.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046593501.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_015515657.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Activation of RAC1";"Nephrin family interactions";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_015509939.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_015509305.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015518557.2	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_015518460.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_046586144.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_015521697.1	18	MetaCyc: PWY-5084;Reactome: R-HSA-70268;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00310+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00620+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-204174;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71403	"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Lysine catabolism";"Pyruvate metabolism";"Glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)"
XP_015520111.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046595693.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015515458.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015524719.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_015509785.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046593506.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046600219.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_015518916.2	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_015514906.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015520130.2	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046597457.1	9	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_046600761.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046589491.1	31	MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-6282;MetaCyc: PWY-8047;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-8012	"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis"
XP_046592264.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046593008.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046586739.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_015524561.1	6	MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_046587593.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046590034.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_046595498.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_015521180.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015524524.2	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)"
XP_015513902.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046602749.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046594727.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_015515101.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588201.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015516036.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046588868.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046600919.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_046596966.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_046593178.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_015517940.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_046586832.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046598711.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046598172.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_015518997.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_046587909.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046596969.1	20	MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7726;Reactome: R-HSA-9033241	"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import"
XP_015510091.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_015524678.2	4	Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_046588758.1	17	Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-113501;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-9616222;Reactome: R-HSA-139915;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-111448	"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Transcriptional regulation of granulopoiesis";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria"
XP_015509641.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_015520536.2	4	KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;Reactome: R-HSA-156582;KEGG: 00633+2.3.1.5	"Caffeine metabolism";"Drug metabolism - other enzymes";"Acetylation";"Nitrotoluene degradation"
XP_015520457.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046590989.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046601898.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046602494.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046594686.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046596743.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_015510055.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046594725.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046591079.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015509416.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046594740.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015513377.2	12	KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042	"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)"
XP_015513576.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015518914.2	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_046587104.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_015522678.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046594840.1	1	Reactome: R-HSA-419771	"Opsins"
XP_015513987.1	4	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2"
XP_015514868.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046596622.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_046597755.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046589247.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_046593419.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046588589.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046595041.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_015518570.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837	"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation"
XP_015509207.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-211733	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Interleukin-1 signaling";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_015514257.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_015516329.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015516185.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015515760.2	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585	"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence"
XP_046602754.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046589039.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015522478.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_015519511.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_046597766.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_046596489.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046587498.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_015523284.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_015516118.2	9	MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;MetaCyc: PWY-7902	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis"
XP_046594276.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_015511367.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594467.1	6	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis"
XP_015517670.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_015521121.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015516598.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046595141.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015521706.2	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_015510079.2	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015510050.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_015520702.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-380320	"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes"
XP_015510662.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_046586842.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046593307.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13	"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system"
XP_015512609.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015515966.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_015511636.2	5	MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_046587699.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_015518753.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_015517312.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_015516622.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046586568.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_015518211.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015523219.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015517706.1	17	Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_015509234.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046601340.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015512965.2	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046599641.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_015510822.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_015519556.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118	"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle"
XP_046600716.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046598593.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046586472.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_046595503.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015512030.1	34	Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9639288;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Amino acids regulate mTORC1";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_015511816.1	6	Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Rho GTPase cycle";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_015516805.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69231	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin D associated events in G1"
XP_015510092.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_015510804.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_015524336.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_015524986.2	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_015516372.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046600082.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_015524471.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_015515045.2	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_046602722.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046601274.1	8	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046597387.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046587791.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046597016.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015521318.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015510023.2	5	KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189	"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046598499.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_046589898.1	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_046597961.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046598869.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046595903.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046592984.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_046585711.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015522245.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046595438.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046592053.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015510866.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046595408.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356	"Ca2+ pathway";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion"
XP_015512520.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015509393.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046587088.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_015521919.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046586708.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_015517049.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_046586367.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046593115.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046600262.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046587504.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_015513688.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046595163.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_015520933.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015523059.2	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046599565.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015523704.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade"
XP_046588768.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046595899.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046594290.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_015524871.1	29	Reactome: R-HSA-3371511;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-5358606	"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_015512084.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046595056.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_046592149.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015519780.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_046592202.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_046586440.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046589693.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_046597043.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046602410.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046586850.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046592734.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046594347.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046597263.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046590571.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines"
XP_046600797.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046589483.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015511193.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015515128.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_015518810.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015524023.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046588832.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046595462.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"Platelet degranulation";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_046592485.1	17	KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789	"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_046592928.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046594548.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046589116.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046587251.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_015520470.2	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_046593431.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_015517656.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_046589218.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Neutrophil degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_015520553.2	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_015517165.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_015513890.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046596553.1	8	KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1	"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II"
XP_015519959.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046598567.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046593618.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_046594362.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-450408	"mTORC1-mediated signalling";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_046599689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591166.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015521617.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046591223.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_015515721.1	10	MetaCyc: PWY-6537;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-4321;MetaCyc: PWY-5022;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19	"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"Propanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation III";"L-glutamate degradation IV";"4-aminobutanoate degradation V";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism"
XP_046600449.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_015511091.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015510874.2	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046597704.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046588407.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_015511097.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_046595152.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046588689.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015510016.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_015516390.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046595897.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046595325.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015521377.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_046590780.1	5	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_015514966.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046590096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046599756.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015513536.2	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_046595505.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport"
XP_046601012.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_015516690.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_015520207.2	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_046599440.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015524054.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015521619.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes"
XP_046585866.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_046602209.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046602816.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046590287.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046600231.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586711.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015515870.2	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046592082.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046597193.1	11	MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-3881;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992	"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation"
XP_046594296.1	8	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046601667.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015520954.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_046591267.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_015523644.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_046590983.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_015523301.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768	"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046595792.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_015513473.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046588590.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_046594790.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046596267.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046589217.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135	"Smooth Muscle Contraction";"Neutrophil degranulation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation"
XP_015509477.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430	"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation"
XP_046597890.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015513630.2	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_046588426.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015515324.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046596204.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046602746.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_015519964.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery"
XP_015511385.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046600408.1	5	KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046597191.1	11	MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-3861	"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II"
XP_046600755.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015510875.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015518186.2	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046585715.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_015512230.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046598632.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_015523661.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_046591482.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046586093.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046594103.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_015522093.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046600420.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592562.1	6	MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_046599564.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046592043.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_015520708.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467	"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs"
XP_015509171.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015516393.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015513734.2	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_046599256.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046587688.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_046601511.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046598365.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046595422.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015514310.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046593104.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046590715.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046588691.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046599881.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_015517922.2	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015521356.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046602748.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046588892.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_015521374.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_015514928.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_046596249.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_015520102.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015518664.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046586536.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_015509841.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015523335.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015513860.2	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_015511351.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569	"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046598505.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015510656.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046586223.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis"
XP_015513510.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046588440.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015512161.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_046588765.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015510947.1	3	Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_046597127.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046600161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015520731.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination"
XP_015516827.2	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_015517981.2	6	Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_046591922.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046587187.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015518576.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046594040.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_015513730.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046588889.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046591006.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046586631.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046585883.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046595249.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046602657.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_015511817.2	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046587332.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046590716.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015513830.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015510233.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046589322.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367	"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis"
XP_015509491.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_046599643.1	5	MetaCyc: PWY-6580;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64	"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_046602006.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015514052.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_046597677.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_046599772.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046597989.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015514828.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046596972.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046591893.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046590548.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046585743.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_015517556.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_015511828.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885	"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins"
XP_015510992.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046598617.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation"
XP_015511315.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046592123.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046588181.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015522554.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015509386.2	4	Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy"
XP_046599865.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046600816.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046592488.1	17	KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_046586884.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_015517965.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046591134.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046598799.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046592666.1	19	Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-428543;Reactome: R-HSA-418885;Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-8964616	"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"Myogenesis";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42"
XP_046600265.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046586542.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-110362	"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair"
XP_046599173.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046602499.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015517745.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_015511768.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_015516657.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection"
XP_046593512.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_015519611.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046596192.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046593674.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015520145.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_046593804.1	11	Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168	"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_046597769.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015517870.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_046600713.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_015516039.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046594935.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046597281.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_015518318.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_015518632.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-203641	"Nephrin family interactions";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"NOSTRIN mediated eNOS trafficking"
XP_046600274.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046600089.1	4	KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_015519700.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046602751.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046590847.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_015509597.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046593013.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046586331.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046601010.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_015511711.1	5	MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
XP_015513552.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_015509552.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046594687.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015522860.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_015512371.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015519358.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015516633.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046596552.1	8	Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826	"Purine salvage";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism"
XP_015520435.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046594609.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046587923.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046593727.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046599852.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_046586737.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046596841.1	8	MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-7199;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes"
XP_015515400.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046591684.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_015523686.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_046601631.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism"
XP_046597200.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601540.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046595977.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha"
XP_046594685.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015515564.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291	"Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C"
XP_046598369.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015515135.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046599907.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046598280.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046591701.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_015510372.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046600883.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046598351.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046598367.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046591813.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015510961.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015519482.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046602333.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_015516846.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046598034.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_015511099.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_015510280.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_015510786.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046593301.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_015521721.1	7	Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"Telomere Extension By Telomerase";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases";"Ub-specific processing proteases"
XP_015523286.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_015509169.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015515567.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601	"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Neddylation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_046600694.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5358346	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis"
XP_046593010.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046600440.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046600277.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046601450.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046588395.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015514574.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046588082.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_015517340.1	3	Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12	"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism"
XP_015521156.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015514376.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015523327.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046602016.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015509911.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_015519274.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_015521632.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046596172.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426496	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs"
XP_015524859.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_046601422.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_015520782.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046587209.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046592855.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_015516400.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_015519625.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_015512291.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_015518687.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_015521649.2	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway"
XP_046594775.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2644606	"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046589953.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange"
XP_046595490.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I"
XP_046592262.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046587140.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_015514393.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_046601874.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046591942.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015524229.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-7587	"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)"
XP_046588421.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046598861.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046592592.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_015522283.2	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046595895.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046591968.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_015516831.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_046600578.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015512537.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046602379.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592583.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_015521196.1	8	Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1	"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis"
XP_046600233.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046585955.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Glycerophospholipid metabolism"
XP_046594808.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046600268.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046594158.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_046600796.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046586710.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_046594661.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046592214.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046592034.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046588888.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046591829.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_046598394.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046601533.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046595053.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046595961.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981	"PPARA activates gene expression";"Endogenous sterols";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics"
XP_046594302.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_015517310.2	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046594958.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046600842.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_015512150.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015519841.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_046597775.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015520008.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_015524423.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015513091.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015509678.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015524929.2	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_015519860.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015512742.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046596326.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Aggrephagy";"Clathrin-mediated endocytosis"
XP_046598774.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046590421.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046600272.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_015514099.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518017.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_015517974.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046595913.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046587056.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015514529.2	14	KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1622;MetaCyc: PWY-8004	"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I"
XP_015512464.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046597569.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046595931.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046588307.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_015510946.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_046595504.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation"
XP_046593686.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_015518889.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046594683.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015514133.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046586689.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046588764.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015524056.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046587264.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046588608.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046602747.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046595882.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046591483.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046587164.1	13	KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-2261;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842	"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II"
XP_015511101.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015518727.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046596744.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_015524957.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046600664.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_046594035.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046592052.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046589165.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962	"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex"
XP_015525039.2	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_046594341.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015512621.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046593061.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046597520.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015523637.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_046593163.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046589309.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046599102.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015512120.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_046587687.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700	"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_015523338.2	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_015522707.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597973.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015523267.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046600270.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046602179.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046599861.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015520762.2	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_015522208.1	5	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_015511076.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_015523707.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_015517117.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_015518900.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046599248.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_015519440.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_046593066.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015522468.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015523336.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7766;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_046595631.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_015516239.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258	"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL"
XP_046589544.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_015515436.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046590570.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses"
XP_046592692.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_015519738.2	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_015514246.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions"
XP_015510481.1	7	KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356	"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_046590490.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015521157.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015511181.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_015523949.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046597003.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-167290	"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation"
XP_046591351.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046597139.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046596372.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_015510968.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046587082.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046588556.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885	"G alpha (12/13) signalling events";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"DCC mediated attractive signaling"
XP_046594239.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046599466.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_046592580.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus"
XP_046591838.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046595854.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_015519534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015521031.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015522662.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046599971.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591347.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway"
XP_046594403.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_015524534.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015511554.2	11	Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2122948	"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_015523366.1	4	Reactome: R-HSA-4755583;Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis"
XP_015512405.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046597934.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015519859.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015509739.2	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015513677.2	5	Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685	"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy";"Pink/Parkin Mediated Mitophagy"
XP_046585691.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015523170.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015518099.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046586760.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015519076.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_046587090.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046600306.1	6	Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_015522504.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046592084.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046599962.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046599864.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015510430.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015518872.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015514913.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046592086.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046601154.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_015522426.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046592486.1	17	MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789	"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Carnitine metabolism";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_015516775.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_015517569.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_015510144.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046591085.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046601529.1	6	KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12	"Galactose metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046585742.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_046586161.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_015515414.2	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046598376.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046598443.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_046595983.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512791.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015524066.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046596349.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_015524607.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046586856.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046590644.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046585861.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046594681.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_015518919.2	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_046601030.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046587471.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046599123.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_015511205.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015521175.2	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_046589191.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046586944.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046598702.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046589571.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015519378.2	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046590027.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_015517662.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046598922.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_015523676.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_015523665.2	11	MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6608;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4	"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine metabolism"
XP_015519146.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046594858.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046594644.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046599574.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046590521.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046587972.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046594343.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046589265.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110328	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046595440.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015523514.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046590664.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_015519659.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046591354.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015510496.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_015512919.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046598297.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046593718.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046598007.1	20	MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_046587442.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_015520319.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015516756.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015514315.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046592795.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514963.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379	"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres"
XP_046600269.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046586857.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046589213.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Neutrophil degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_015510728.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_015524822.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015523798.1	8	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1"
XP_046589711.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230	"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA"
XP_046600336.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-881907	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_015513006.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046594549.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_015520429.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015511321.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046587235.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015515649.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046602533.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_015510626.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_015515874.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_046591959.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046599669.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism"
XP_015522710.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_015519603.1	20	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5656169	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis"
XP_015513202.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046588551.1	12	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Rho GTPase cycle";"mTOR signaling pathway"
XP_015520661.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015517386.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015523409.1	3	MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8	"L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation"
XP_046602056.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046597877.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015522251.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015510708.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597726.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046600108.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_015520206.2	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_015518469.1	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_015511360.2	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046598419.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046588390.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046595134.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015510713.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015520438.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015521458.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046590949.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788	"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling"
XP_046593744.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_046596240.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046600335.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046587680.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459	"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046589231.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046600859.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046592561.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_015515301.2	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_015511535.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046599909.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046590663.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046602433.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015516027.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046586368.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy"
XP_046596608.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_015524306.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046591979.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_015521303.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_015516167.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046597483.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046600208.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015522667.2	6	KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_046585936.1	5	MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III"
XP_046600779.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-389513	"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling"
XP_046595103.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_046589314.1	8	KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;Reactome: R-HSA-6787639;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-5739	"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis"
XP_015514467.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046593434.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_015514423.2	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_015519394.1	6	MetaCyc: PWY-6722;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5789	"Candicidin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_015520783.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046585740.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_015515270.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015516510.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046597978.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2"
XP_046598390.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015523292.1	11	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway"
XP_015509390.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638	"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway"
XP_015518385.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015521171.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482788	"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC"
XP_015515591.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_015522902.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046602802.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046594704.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046590908.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046593474.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692	"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity"
XP_046597452.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046587697.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_015524353.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_015512818.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015510710.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015514202.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015514948.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046586136.1	5	Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26	"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism"
XP_015515815.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_015515914.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815	"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D"
XP_015517574.2	29	KEGG: 04150+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6804757;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3371453;Reactome: R-HSA-5693568;Reactome: R-HSA-6803207;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Human cytomegalovirus infection";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Degradation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Stabilization of p53";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Nonhomologous End-Joining (NHEJ)";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_015513052.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015516188.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046598904.1	39	Reactome: R-HSA-5654733;Reactome: R-HSA-1257604;Reactome: R-HSA-5654719;Reactome: R-HSA-5654720;Reactome: R-HSA-2033514;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-5654712;Reactome: R-HSA-190373;Reactome: R-HSA-5654699;Reactome: R-HSA-8853338;Reactome: R-HSA-190372;Reactome: R-HSA-5654710;Reactome: R-HSA-5654688;Reactome: R-HSA-5654732;Reactome: R-HSA-5658623;Reactome: R-HSA-1839130;Reactome: R-HSA-190322;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-5654219;Reactome: R-HSA-5654689;Reactome: R-HSA-5654221;Reactome: R-HSA-2033519;Reactome: R-HSA-190371;Reactome: R-HSA-5654687;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-1839122;Reactome: R-HSA-190375;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-5654700;Reactome: R-HSA-5654704;Reactome: R-HSA-5654706;Reactome: R-HSA-5655253;Reactome: R-HSA-5654228	"Negative regulation of FGFR4 signaling";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR4";"FGFR3 mutant receptor activation";"PI3K Cascade";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"FRS-mediated FGFR4 signaling";"FGFR1c ligand binding and activation";"SHC-mediated cascade:FGFR2";"Signaling by FGFR3 point mutants in cancer";"FGFR3c ligand binding and activation";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR1";"Negative regulation of FGFR3 signaling";"FGFRL1 modulation of FGFR1 signaling";"Signaling by activated point mutants of FGFR3";"FGFR4 ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade: FGFR1";"PI-3K cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR2";"Activated point mutants of FGFR2";"FGFR3b ligand binding and activation";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Signaling by activated point mutants of FGFR1";"FGFR2c ligand binding and activation";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR2 signaling";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR3 signaling";"Signaling by FGFR2 in disease";"Phospholipase C-mediated cascade, FGFR4"
XP_046602646.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046598865.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_015513727.2	31	Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-8012;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5366	"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)"
XP_015513143.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015510228.2	20	MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_046595892.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046592655.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046596488.1	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015524049.2	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046595025.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228	"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix"
XP_015521192.1	8	KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_015523950.2	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
XP_015515263.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015516717.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_015516835.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046590681.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_015510052.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046601900.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046588393.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046588200.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015512781.1	13	MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-5122	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis"
XP_015513317.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015511348.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015523419.2	4	KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50	"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_015513045.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046590058.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511521.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015515715.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism"
XP_015519131.2	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_015515837.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_015524861.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015521357.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046602429.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046597379.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_046596692.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046589185.1	13	Reactome: R-HSA-2029485;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-2871796	"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"DAP12 signaling";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation"
XP_046591817.1	14	MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-5981	"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III"
XP_015521283.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_015513507.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046586817.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015521431.1	18	Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166	"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Synthesis of PA"
XP_046598156.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-2151201	"HATs acetylate histones";"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis"
XP_015524608.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_046596269.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015520884.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066	"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046601982.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015509976.2	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_015512963.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046589691.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046598948.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_015520469.2	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_046593883.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588779.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_015515862.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046593133.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_015515746.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046589099.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046595588.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046587401.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015511660.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_015519990.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046589117.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015522585.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_015517525.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_015515305.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017	"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046594778.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015518272.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015514803.2	16	Reactome: R-HSA-5602680;Reactome: R-HSA-5603037;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-6811558;Reactome: R-HSA-209543;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-3134963;Reactome: R-HSA-1810476;Reactome: R-HSA-975138	"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR5)";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"p75NTR recruits signalling complexes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_015516505.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_015522202.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_046595955.1	11	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"p38MAPK events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046600326.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046599753.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_015512817.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046593165.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046596168.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_015518623.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015524803.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015511963.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_015512796.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046599846.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046592560.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_015521370.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813	"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids"
XP_015522198.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_015513710.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-5221030	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA"
XP_015512953.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_015518784.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046596258.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046597262.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046599984.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_015517321.2	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_015514147.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046596114.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_015520839.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015510427.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015522573.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5871	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_015520634.2	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_015519228.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167242	"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_015521233.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_046587447.1	17	Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956	"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"Downstream TCR signaling";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway"
XP_046595207.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046588945.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046592891.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015514331.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_015519233.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_046587686.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence"
XP_015509685.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046600307.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_046590427.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015521821.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015511964.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046595890.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III"
XP_015518613.2	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046600780.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-2467813	"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids"
XP_015522061.2	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046601201.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046594412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046587455.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_015512854.2	7	MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_015520305.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015521683.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015523975.2	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_046586823.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_015515748.1	29	KEGG: 00071+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6802;MetaCyc: PWY-5078;MetaCyc: PWY-5751;MetaCyc: PWY-6313;MetaCyc: PWY-7396;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5057;MetaCyc: PWY-7013;MetaCyc: PWY-7118;MetaCyc: PWY-5076;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6871;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-6342;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1	"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Naphthalene degradation";"L-methionine degradation III";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"Salidroside biosynthesis";"L-isoleucine degradation II";"Phenylethanol biosynthesis";"Serotonin degradation";"Butanol and isobutanol biosynthesis (engineered)";"Chloroalkane and chloroalkene degradation";"Acetaldehyde biosynthesis I";"Tyrosine metabolism";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"(S)-propane-1,2-diol degradation";"Chitin degradation to ethanol";"L-leucine degradation III";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol III";"3-methylbutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"L-phenylalanine degradation III";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450"
XP_046594405.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046589184.1	13	Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"DAP12 signaling";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_046590017.1	14	Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634	"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport"
XP_015512193.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_046599418.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_015519709.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-977225;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-5693571;Reactome: R-HSA-606279	"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"HATs acetylate histones";"Amyloid fiber formation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"HDACs deacetylate histones";"DNA methylation";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_015514937.1	6	Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292	"Hyaluronan uptake and degradation";"HS-GAG degradation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome"
XP_046597270.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046586833.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_015509432.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_015509178.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-7124	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)"
XP_046598780.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046589277.1	11	MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6608;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4	"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Purine metabolism"
XP_046591005.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046599020.1	16	Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519	"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression"
XP_046585978.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046586129.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046590417.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_046600577.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046592442.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046602666.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377	"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins"
XP_015516388.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046587058.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015524983.2	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046591960.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_015519949.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_046592766.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046590056.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015514143.1	5	Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-5668599	"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases"
XP_015521035.2	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_015509677.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
XP_046591119.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046602511.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046600917.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_046590063.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046602331.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046599313.1	5	KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_015521647.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015520148.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_015524976.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046598346.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046594849.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592303.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046599425.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046593770.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046589388.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_015522633.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_015520640.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046592963.1	14	MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_015522994.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046590980.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046601711.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015524977.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046586324.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation"
XP_015523316.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046596994.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_015522717.1	8	MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-5739	"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis"
XP_015523119.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046590572.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses"
XP_015521944.1	10	Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"EGFR downregulation";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis"
XP_046600876.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046598397.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_015510952.2	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_046594679.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_015514989.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_015515627.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015511898.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_015513346.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046598770.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015520224.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015514047.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_015514604.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation"
XP_046602344.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_015509853.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046596842.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015516708.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015523224.1	9	MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-6146;Reactome: R-HSA-3371599	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_046589430.1	14	Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Aggrephagy";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Macroautophagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046599525.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015522529.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046588784.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_015522250.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046598089.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_015524500.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046597948.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594045.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_046589490.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-7746;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367	"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis"
XP_046593844.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015519757.1	6	Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-5632684	"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state"
XP_015522752.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8955332	"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Gap junction assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin"
XP_046599910.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_046596202.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_015521659.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_015515640.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015514957.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046587990.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015510396.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015523562.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_046591138.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015512816.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046595023.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046596036.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015519920.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046592872.1	33	Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531	"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"tRNA processing in the nucleus"
XP_046597979.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046600305.1	6	MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_046592251.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_046589917.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015521149.2	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_015512605.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046595136.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015518679.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015524247.2	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_015515712.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015519126.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046594413.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_046596263.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_015509748.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015520220.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046601344.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046589036.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015514383.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_046594410.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046588662.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046597817.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046592581.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_015523523.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046593600.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046595208.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046591513.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase"
XP_046596213.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046596216.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046597284.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_046602702.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015514797.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015516635.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046591672.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046599081.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046598289.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015514264.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046597244.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA"
XP_046586802.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046591311.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046596449.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046598592.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_015511035.1	33	Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-167246;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation"
XP_015519114.1	13	Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400	"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046601979.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015518391.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046596174.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_015510840.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046595785.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593715.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway"
XP_015522340.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases"
XP_046586296.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046592263.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592460.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_015512772.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015513816.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_015521991.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_015516229.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594005.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015518113.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015523516.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046592702.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046592260.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046587526.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases"
XP_015511150.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_046598766.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015515647.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511240.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046592057.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015519403.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015519900.2	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_015511497.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046595130.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015517969.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046599966.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046593554.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_015524747.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_015515088.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594755.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511557.1	5	KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883	"Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG"
XP_046597186.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_015514287.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046591763.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597190.1	11	KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659	"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis"
XP_046592212.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015524498.2	5	KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)"
XP_046598257.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046590295.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046600665.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_015514138.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015514939.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046601298.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_015516252.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555	"Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1"
XP_046601519.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015515340.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046595288.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015512782.1	13	MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-5123	"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_046596887.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586559.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046586135.1	5	Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26	"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism"
XP_015510533.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_015516522.1	7	MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2	"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism"
XP_015523310.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046590392.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015516040.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_046594785.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046602302.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597889.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046600708.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015513336.1	19	Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"Myogenesis";"RHO GTPases Activate Formins";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"EGFR downregulation";"GPVI-mediated activation cascade";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs"
XP_046586192.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046588552.1	12	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Rho GTPase cycle";"mTOR signaling pathway"
XP_015515811.2	8	Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_015510047.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_046587045.1	8	MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_015511874.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_015518262.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046594826.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046591408.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015517367.2	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_015509544.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015510101.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_046590144.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_015517994.2	5	MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_046586183.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046601698.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015524868.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046596464.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046587722.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046600924.1	17	Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571	"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)"
XP_046589438.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046589655.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046601877.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046589849.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046586602.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_015518009.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_015524751.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046594226.1	18	Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925	"Synthesis of PA";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG"
XP_046602720.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046590486.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046592112.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_015518559.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046596808.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046594229.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046599264.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601786.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015515060.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_015513262.2	11	KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism"
XP_046598033.1	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation"
XP_015522859.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046590799.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_015517683.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015515899.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_015519595.2	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_046591049.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589485.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046589806.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_015509595.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_046591481.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex"
XP_015522135.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_046595887.1	6	MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-7442	"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis"
XP_046599894.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015514298.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_015514734.1	6	Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225;Reactome: R-HSA-3000171	"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions"
XP_015521438.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046595150.1	12	MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_015524527.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046588754.1	10	Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11	"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism"
XP_046593550.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF/MAP kinase cascade"
XP_046591694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046595543.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_015521067.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_046599181.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_046594437.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015511015.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_015517916.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046596006.1	13	Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_046588289.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511550.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_015518420.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046597582.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins"
XP_046590323.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation"
XP_046597705.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046595239.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046586725.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015518199.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046595019.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-6785807;Reactome: R-HSA-8878166	"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2"
XP_046594604.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015520844.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_015522289.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046591658.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015517362.1	4	KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_046591405.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_015519167.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_015523749.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_015514919.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015512603.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015513806.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046592378.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015524821.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015513138.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_015511257.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015510839.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046599150.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_015514074.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_046594786.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_046589791.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015518185.2	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_015518796.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046586585.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015511364.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_046598690.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_015524526.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_015512899.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046597606.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046602253.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015514012.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046593521.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis"
XP_015524008.1	42	MetaCyc: PWY-6863;MetaCyc: PWY-7007;MetaCyc: PWY-7216;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7656;MetaCyc: PWY-7726;MetaCyc: PWY-1361;MetaCyc: PWY-7606;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5177;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-5109;KEGG: 00720+4.2.1.17+1.1.1.35	"Pyruvate fermentation to hexanol (engineered)";"Methyl ketone biosynthesis (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Geraniol degradation";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Spodoptera littoralis pheromone biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Benzoyl-coa degradation I (aerobic)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Caprolactam degradation";"Fatty acid salvage";"Phenylalanine metabolism";"Lysine degradation";"Fatty acid elongation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Benzoate degradation";"Androstenedione degradation";"Glutaryl-coa degradation";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Valine, leucine and isoleucine degradation";"Toluene degradation";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fermentation to 2-methylbutanoate";"Carbon fixation pathways in prokaryotes"
XP_015519258.1	8	Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015522557.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_015523642.2	8	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_015515349.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_015510860.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046591714.1	7	KEGG: 00280+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00650+4.1.3.4	"Valine, leucine and isoleucine degradation";"Synthesis of Ketone Bodies";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Butanoate metabolism"
XP_046594293.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_046593834.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046594856.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046600207.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046599153.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_015514886.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_015518695.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
XP_046601835.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015510637.2	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046587210.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015524697.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015519243.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22	"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_015509623.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591819.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_015514024.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015520594.2	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_015516796.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046592135.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_015522293.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015513956.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046586198.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046601196.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046600984.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046587055.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_015517121.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015514753.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_015523422.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_015522329.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015510195.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046586603.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_015518414.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_015511045.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18	"Heme degradation";"Iron uptake and transport";"Heme degradation I";"Porphyrin and chlorophyll metabolism"
XP_015519199.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015515519.2	15	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_046594865.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015515264.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046596205.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597024.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_015517434.2	5	Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_015510993.1	1	Reactome: R-HSA-419771	"Opsins"
XP_015522556.2	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046594760.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046596845.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015515543.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015514718.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_015516654.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046601293.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592609.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_046600226.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046596962.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046586420.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046586909.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046596587.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046602237.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015518759.2	13	Reactome: R-HSA-3000171;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919	"Non-integrin membrane-ECM interactions";"Signaling by PDGF";"Integrin cell surface interactions";"NCAM1 interactions";"Extracellular matrix organization";"Collagen degradation";"Laminin interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Collagen chain trimerization";"Crosslinking of collagen fibrils"
XP_046592890.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046590502.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015515361.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015523604.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015512522.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046599251.1	7	MetaCyc: PWY-46;MetaCyc: PWY-31;MetaCyc: PWY-6922;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984	"Putrescine biosynthesis III";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle"
XP_015516256.1	12	Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897	"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Macroautophagy";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes"
XP_046594177.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046588193.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046586885.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046594046.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_015516497.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046592789.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_046602809.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015512856.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591317.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046587103.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015522355.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046598684.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046599635.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-5140745	"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_046589916.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015510633.2	8	MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826	"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism"
XP_046588753.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)"
XP_046590044.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046586609.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_015514761.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_015509276.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046587588.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015524693.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046596839.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_015517680.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046592120.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015509280.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_015516994.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046586462.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176412	"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C"
XP_015520616.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046599634.1	8	Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873	"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation"
XP_015511799.1	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol"
XP_046593774.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015512076.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015524563.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_015515316.1	19	KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5172;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V"
XP_015524053.2	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015521404.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046596256.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601348.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015520222.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_015510321.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046594433.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591547.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046597797.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7410	"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis"
XP_046593271.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_015515580.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015511890.2	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015511343.1	11	MetaCyc: PWY-5123;MetaCyc: PWY-7391;MetaCyc: PWY-6383;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7560;MetaCyc: PWY-6859;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7102	"Trans, trans-farnesyl diphosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_046591496.1	7	Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684	"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Activation of SMO";"Hedgehog 'on' state"
XP_046590205.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046601497.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_015520422.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046600644.1	12	MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340	"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Selenate reduction";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Purine metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation"
XP_046589957.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_015509999.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015510670.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046595740.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046593983.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015523605.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046586574.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_046590935.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015511485.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015510689.1	25	Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-380270;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"Recruitment of mitotic centrosome proteins and complexes";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015518023.2	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5743	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle"
XP_046596910.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015509554.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046590366.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_015522266.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046599332.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046589854.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_015518862.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046590533.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_015524869.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046601961.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046588867.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015511503.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition"
XP_015513391.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015511458.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046587446.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation"
XP_046599430.1	6	KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7077;MetaCyc: PWY-7395	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_046590779.1	5	KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757	"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_046599157.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_015513060.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046594022.1	7	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V"
XP_046586532.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046597257.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046590907.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015514051.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_015510403.2	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_046588275.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_046585902.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_015524864.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_046599688.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015513474.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-1655829	"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_015524399.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159231	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046589496.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_015510555.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-201681	"RHO GTPases Activate Formins";"Degradation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT"
XP_015520665.2	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_046602808.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015514365.2	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_046595726.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046589239.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046590365.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_015523578.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046597396.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015509338.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046589977.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_015524898.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046598949.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_015518236.2	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_015520652.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015522673.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046589342.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046589276.1	11	MetaCyc: PWY-6607;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6608;Reactome: R-HSA-8851680	"Guanosine nucleotides degradation I";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation II";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions"
XP_046591339.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling"
XP_015519421.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046602005.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046595409.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775	"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Ion homeostasis"
XP_046596956.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046597148.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046600769.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046601783.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015519660.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination"
XP_046593057.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_015519832.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046593850.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046597216.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046595964.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046598497.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_015524259.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015522128.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046592783.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_015510828.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015511712.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467	"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Aggrephagy";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs"
XP_046589259.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015510150.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046601343.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015521849.2	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_015524604.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_015523280.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046592709.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046596896.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_046593207.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046589489.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-8012;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7746;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7723;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7663	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Bacterial bioluminescence";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)"
XP_046594574.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046602718.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046599489.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015523765.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046601604.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046599769.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015519049.2	8	KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_015520633.2	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046600673.1	9	MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_046592167.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588391.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046589872.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015513598.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046596629.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_046593513.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719	"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors"
XP_015513812.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046602404.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046598745.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046590934.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015519960.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015515019.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_046591165.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046592030.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015514999.1	8	KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5049;MetaCyc: PWY-3581;MetaCyc: PWY-5394;KEGG: 00350+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133	"Folate biosynthesis";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II"
XP_046595210.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046600878.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046591958.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046591989.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_046586728.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046595960.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211976	"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Endogenous sterols"
XP_046592427.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046601936.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046589115.1	12	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;MetaCyc: PWY-7221	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis"
XP_015521813.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_015514839.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_015519436.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046601150.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046601779.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046589411.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046599100.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015522156.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046599002.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_015520019.1	39	Reactome: R-HSA-5654710;Reactome: R-HSA-1839130;Reactome: R-HSA-5658623;Reactome: R-HSA-5654732;Reactome: R-HSA-5654688;Reactome: R-HSA-5654719;Reactome: R-HSA-5654720;Reactome: R-HSA-1257604;Reactome: R-HSA-5654733;Reactome: R-HSA-190372;Reactome: R-HSA-5654699;Reactome: R-HSA-8853338;Reactome: R-HSA-5654712;Reactome: R-HSA-190373;Reactome: R-HSA-2033514;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-5654727;Reactome: R-HSA-5654726;Reactome: R-HSA-5654228;Reactome: R-HSA-5654706;Reactome: R-HSA-5654704;Reactome: R-HSA-5655253;Reactome: R-HSA-5654700;Reactome: R-HSA-6811558;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-5654687;Reactome: R-HSA-5654689;Reactome: R-HSA-2033519;Reactome: R-HSA-5654221;Reactome: R-HSA-190371;Reactome: R-HSA-190322;Reactome: R-HSA-5654227;Reactome: R-HSA-5655302;Reactome: R-HSA-5654219;Reactome: R-HSA-190375;Reactome: R-HSA-1839122	"PI-3K cascade:FGFR3";"Signaling by activated point mutants of FGFR3";"FGFRL1 modulation of FGFR1 signaling";"Negative regulation of FGFR3 signaling";"SHC-mediated cascade:FGFR1";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR4";"PIP3 activates AKT signaling";"Negative regulation of FGFR4 signaling";"FGFR3c ligand binding and activation";"SHC-mediated cascade:FGFR2";"Signaling by FGFR3 point mutants in cancer";"FRS-mediated FGFR4 signaling";"FGFR1c ligand binding and activation";"FGFR3 mutant receptor activation";"PI3K Cascade";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR1 signaling";"Phospholipase C-mediated cascade, FGFR4";"FRS-mediated FGFR3 signaling";"SHC-mediated cascade:FGFR3";"Signaling by FGFR2 in disease";"FRS-mediated FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR1";"Activated point mutants of FGFR2";"Phospholipase C-mediated cascade, FGFR2";"FGFR3b ligand binding and activation";"FGFR4 ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade: FGFR1";"FGFR2c ligand binding and activation";"Signaling by activated point mutants of FGFR1"
XP_046601013.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_015518950.2	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015513164.2	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_046593288.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046591074.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_015511180.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_046596888.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586566.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_015519090.2	5	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway"
XP_046587600.1	32	Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-112382	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex"
XP_046588680.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_046593666.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_046591970.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_015518415.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_046589384.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046590303.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046599914.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046592104.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046600901.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_015513963.1	7	MetaCyc: PWY-46;MetaCyc: PWY-31;Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1	"Putrescine biosynthesis III";"Canavanine degradation";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism"
XP_015519983.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_015518261.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015519766.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046593784.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5467348	"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex"
XP_015517571.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism"
XP_046595849.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046599333.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568	"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Attenuation phase"
XP_046591503.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046601510.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015516277.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015524972.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015515645.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_015512250.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588893.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_015518392.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046589432.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"Aggrephagy";"MHC class II antigen presentation"
XP_046599480.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046602328.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_015511160.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046591769.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046593067.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_015523891.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015516806.2	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_046591266.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046602518.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046590023.1	14	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism"
XP_046594024.1	7	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Neutrophil degranulation";"Starch degradation II";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_015515978.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_015520085.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046591818.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7417	"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_015520567.1	12	MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_046598776.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015519168.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046601906.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046600391.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015517631.1	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_015511146.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_015512044.2	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046601163.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046589315.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1538133	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G0 and Early G1"
XP_046597446.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594773.1	14	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Neutrophil degranulation";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046597945.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015521342.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046601130.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046586338.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_015519836.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046600498.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046597444.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046591477.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_046596271.1	10	MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
XP_046585871.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015513252.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046591384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593295.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046589758.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046598536.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519	"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"HATs acetylate histones";"Estrogen-dependent gene expression"
XP_015512359.1	4	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_015518974.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
XP_015516389.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015515014.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015516193.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_046596811.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Heme biosynthesis"
XP_015514137.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046585867.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_046586422.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015510939.2	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046594232.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015524752.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046594861.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015513886.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046597384.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_015514019.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_015512028.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015524626.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015521559.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_015517737.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_015517744.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484	"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_015518273.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015510205.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_046601696.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_015523135.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_015521393.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046596257.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593246.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_015513960.2	13	MetaCyc: PWY-7384;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)"
XP_046591659.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015522077.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-112382	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex"
XP_015520439.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046590423.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046594710.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_015516370.1	7	Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_015514953.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015523491.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046591356.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046592083.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046598305.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046599855.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_046594814.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015516825.2	8	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046597796.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7721	"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis"
XP_046591971.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046592312.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046598914.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015517980.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046596843.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015519962.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015514265.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046600220.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046601689.1	30	Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-2564830;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_046602810.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046593514.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046601543.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046599935.1	1	Reactome: R-HSA-156581	"Methylation"
XP_015517420.2	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_015509154.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-879415	"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling"
XP_046594104.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_015513696.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046594032.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972	"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046595889.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3	"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism"
XP_015518188.2	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_015520879.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-111932	"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB"
XP_015524438.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046585940.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046597215.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015514927.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015512079.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046599636.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046589437.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046587762.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046600052.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046600628.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_046591484.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046599824.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015513390.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_046592261.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015516073.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_015519866.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4641258	"Interleukin-1 signaling";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL"
XP_015519113.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046591474.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_046587315.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_015513722.2	7	MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046592458.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_015515987.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046600982.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046593322.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015523311.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015517724.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_015524248.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015511530.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046587083.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_015518965.1	7	Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500	"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle"
XP_046592800.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_015510378.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046595121.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-4086398	"G alpha (z) signalling events";"G-protein activation";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway"
XP_015520383.1	18	MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism"
XP_046591287.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-3371453;Reactome: R-HSA-6803207;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-6804757	"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Stabilization of p53";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Human cytomegalovirus infection";"Thermogenesis";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Degradation"
XP_015516360.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046598921.1	5	MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_046586706.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046601085.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_015514191.2	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_015523141.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586142.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_015516793.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015509302.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282	"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_046595860.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046590039.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015516275.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015519296.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015512478.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046599600.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046592822.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_015523985.1	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_046591506.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046595586.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015516342.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046596957.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015513068.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702	"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling"
XP_046588949.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_046596848.1	8	Reactome: R-HSA-73614;MetaCyc: PWY-7181;MetaCyc: PWY-7199;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5	"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine metabolism"
XP_015512273.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_015510544.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046600886.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046597046.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015509729.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_015524155.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046591974.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046591862.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046591667.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596658.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046590550.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046601304.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015518461.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_046593026.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046599340.1	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046586616.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015513112.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015519386.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046597524.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015521109.2	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_015522401.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-1912408;Reactome: R-HSA-6804114;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585;Reactome: R-HSA-69231	"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Transcriptional regulation of granulopoiesis";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence";"Cyclin D associated events in G1"
XP_015521170.2	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_046594779.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015519395.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046592050.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_015512324.2	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_015510143.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_015514341.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Photosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046591389.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046602293.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046592016.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046587143.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046597974.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_015511861.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_046602010.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015513158.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046591086.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015524625.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_015516895.2	19	Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497	"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Chylomicron assembly";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Scavenging by Class H Receptors"
XP_046594619.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046585947.1	3	KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_046594246.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015510635.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015510423.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046593746.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_015509524.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046602343.1	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_046592853.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_015514801.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015515597.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046588576.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046598006.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism"
XP_015522619.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046601537.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046592536.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046599624.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046598270.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_046589900.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046586448.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046594582.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046593353.1	9	MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-7902	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis"
XP_046591475.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_046586707.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015516506.1	22	MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-5353;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-7592	"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_046589770.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_015512378.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046591251.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis"
XP_046597078.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_015515602.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015516815.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046596686.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_015511115.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_015515547.2	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046592040.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046597144.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions"
XP_015519956.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046602015.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015516519.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453	"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response"
XP_015523397.2	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_015517899.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-389977	"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Recycling pathway of L1";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway"
XP_015510374.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_015522919.1	179	Reactome: R-HSA-2979096;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-9033241;Reactome: R-HSA-2467813;Reactome: R-HSA-6791226;Reactome: R-HSA-6782210;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-209543;Reactome: R-HSA-5689901;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-174490;Reactome: R-HSA-174084;Reactome: R-HSA-450321;Reactome: R-HSA-1295596;Reactome: R-HSA-936440;Reactome: R-HSA-8856828;Reactome: R-HSA-5675482;Reactome: R-HSA-8939902;Reactome: R-HSA-937041;Reactome: R-HSA-2644606;Reactome: R-HSA-9615710;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-9014325;Reactome: R-HSA-4641263;Reactome: R-HSA-1253288;Reactome: R-HSA-975110;Reactome: R-HSA-75815;Reactome: R-HSA-1236382;Reactome: R-HSA-5205685;Reactome: R-HSA-180585;Reactome: R-HSA-5696394;Reactome: R-HSA-179409;Reactome: R-HSA-205043;Reactome: R-HSA-72706;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-6781823;Reactome: R-HSA-8875360;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-9637628;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-156827;Reactome: R-HSA-9646399;Reactome: R-HSA-9020702;Reactome: R-HSA-69541;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-8849469;Reactome: R-HSA-8863795;Reactome: R-HSA-382556;Reactome: R-HSA-937039;Reactome: R-HSA-8856825;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-5675221;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5357956;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-5696395;Reactome: R-HSA-2173788;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2559582;Reactome: R-HSA-532668;Reactome: R-HSA-349425;Reactome: R-HSA-445989;Reactome: R-HSA-6804756;Reactome: R-HSA-72764;Reactome: R-HSA-110314;Reactome: R-HSA-175474;Reactome: R-HSA-5689896;Reactome: R-HSA-3134975;Reactome: R-HSA-2173791;Reactome: R-HSA-156902;Reactome: R-HSA-2565942;Reactome: R-HSA-8939236;Reactome: R-HSA-168638;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-1358803;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-5689877;Reactome: R-HSA-168928;Reactome: R-HSA-192823;Reactome: R-HSA-3322077;Reactome: R-HSA-936964;Reactome: R-HSA-182971;Reactome: R-HSA-8866652;Reactome: R-HSA-5357905;Reactome: R-HSA-4608870;Reactome: R-HSA-5696400;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-901032;Reactome: R-HSA-9013973;Reactome: R-HSA-2408557;Reactome: R-HSA-5693565;Reactome: R-HSA-2122948;Reactome: R-HSA-5693607;Reactome: R-HSA-187577;Reactome: R-HSA-5685942;Reactome: R-HSA-174048;Reactome: R-HSA-8854050;Reactome: R-HSA-6804760;Reactome: R-HSA-5654733;Reactome: R-HSA-5610785;Reactome: R-HSA-937072;Reactome: R-HSA-9013507;Reactome: R-HSA-168927;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-6804757;Reactome: R-HSA-400253;Reactome: R-HSA-2559585;Reactome: R-HSA-174113;Reactome: R-HSA-1799339;Reactome: R-HSA-69231;Reactome: R-HSA-5654726;Reactome: R-HSA-209560;Reactome: R-HSA-917937;Reactome: R-HSA-9636383;Reactome: R-HSA-9645460;Reactome: R-HSA-6807004;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-201681;Reactome: R-HSA-1169408;Reactome: R-HSA-110320;Reactome: R-HSA-69481;Reactome: R-HSA-2672351;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5676590;Reactome: R-HSA-975144;Reactome: R-HSA-3785653;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5696397;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-5655862;Reactome: R-HSA-68949;Reactome: R-HSA-2173795;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-917729;Reactome: R-HSA-110312;Reactome: R-HSA-450302;Reactome: R-HSA-5654732;Reactome: R-HSA-9633012;Reactome: R-HSA-9613829;Reactome: R-HSA-975163;Reactome: R-HSA-162588;Reactome: R-HSA-4641258;Reactome: R-HSA-977225;Reactome: R-HSA-912631;Reactome: R-HSA-174184;Reactome: R-HSA-8948747;Reactome: R-HSA-5684264;Reactome: R-HSA-937042;Reactome: R-HSA-6782135;Reactome: R-HSA-2871837;Reactome: R-HSA-8876493;Reactome: R-HSA-5610783;Reactome: R-HSA-1234176;Reactome: R-HSA-5656121	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Peroxisomal protein import";"Separation of Sister Chromatids";"Major pathway of rRNA processing in the nucleolus and cytosol";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"p75NTR recruits signalling complexes";"Metalloprotease DUBs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Membrane binding and targetting of GAG proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Spry regulation of FGF signaling";"Negative regulators of DDX58/IFIH1 signaling";"Clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"Regulation of RUNX2 expression and activity";"IKK complex recruitment mediated by RIP1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Late endosomal microautophagy";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of FZD by ubiquitination";"Downregulation of ERBB4 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Pink/Parkin Mediated Mitophagy";"Vif-mediated degradation of APOBEC3G";"DNA Damage Recognition in GG-NER";"APC-Cdc20 mediated degradation of Nek2A";"NRIF signals cell death from the nucleus";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Formation of TC-NER Pre-Incision Complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Modulation by Mtb of host immune system";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"L13a-mediated translational silencing of Ceruloplasmin expression";"Aggrephagy";"Interleukin-1 signaling";"Stabilization of p53";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of ERBB2 signaling";"ABC-family proteins mediated transport";"IRAK1 recruits IKK complex";"Cargo recognition for clathrin-mediated endocytosis";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MAPK pathway";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"TNFR1-induced NFkappaB signaling pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Formation of Incision Complex in GG-NER";"Downregulation of TGF-beta receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Senescence-Associated Secretory Phenotype (SASP)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Autodegradation of the E3 ubiquitin ligase COP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TP53 Activity through Phosphorylation";"Eukaryotic Translation Termination";"Recognition of DNA damage by PCNA-containing replication complex";"Assembly Of The HIV Virion";"Ovarian tumor domain proteases";"Regulation of innate immune responses to cytosolic DNA";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Peptide chain elongation";"Regulation of PLK1 Activity at G2/M Transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NOD1/2 Signaling Pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2:ERBB3 signaling";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"Josephin domain DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Viral mRNA Translation";"Glycogen synthesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"EGFR downregulation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TNFR1 signaling";"Asymmetric localization of PCP proteins";"Dual Incision in GG-NER";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"ER Quality Control Compartment (ERQC)";"TICAM1-dependent activation of IRF3/IRF7";"Selenocysteine synthesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated NOTCH1 Transmits Signal to the Nucleus";"Processing of DNA double-strand break ends";"SCF(Skp2)-mediated degradation of p27/p21";"HDR through Homologous Recombination (HRR)";"APC/C:Cdc20 mediated degradation of Cyclin B";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of TP53 Activity through Methylation";"Negative regulation of FGFR4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"TICAM1, RIP1-mediated IKK complex recruitment";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"Regulation of TP53 Degradation";"Circadian Clock";"Oncogene Induced Senescence";"SCF-beta-TrCP mediated degradation of Emi1";"SRP-dependent cotranslational protein targeting to membrane";"Cyclin D associated events in G1";"Negative regulation of FGFR1 signaling";"NF-kB is activated and signals survival";"Iron uptake and transport";"Prevention of phagosomal-lysosomal fusion";"Alpha-protein kinase 1 signaling pathway";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"TCF dependent signaling in response to WNT";"ISG15 antiviral mechanism";"Translesion Synthesis by POLH";"G2/M Checkpoints";"Stimuli-sensing channels";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NIK-->noncanonical NF-kB signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Myoclonic epilepsy of Lafora";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Translesion synthesis by POLK";"Orc1 removal from chromatin";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Translesion synthesis by REV1";"activated TAK1 mediates p38 MAPK activation";"Negative regulation of FGFR3 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Chaperone Mediated Autophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Budding and maturation of HIV virion";"Degradation of DVL";"Amyloid fiber formation";"Regulation of signaling by CBL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN localization";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IRAK2 mediated activation of TAK1 complex";"Dual incision in TC-NER";"FCERI mediated NF-kB activation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of GLI2 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Translesion synthesis by POLI"
XP_015520574.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_015511955.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_015511024.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_046592126.1	7	MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-7886	"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_015521131.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046596609.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046594500.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046602057.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_015519445.2	19	Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-8856828;Reactome: R-HSA-202733	"LDL remodeling";"Scavenging by Class F Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"VLDL assembly";"Regulation of TLR by endogenous ligand";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class A Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall"
XP_046598797.1	4	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)"
XP_046587069.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_015509371.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_015515112.2	12	KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-6672;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857	"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis"
XP_015509144.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_015519810.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha"
XP_015510196.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_015522420.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_015510081.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046595990.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA"
XP_046596809.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_015521812.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_015509370.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015516038.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_046599124.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046591914.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046594404.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_015513107.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046602329.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046599301.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_015509177.1	16	MetaCyc: PWY-7124;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-8004	"Ethylene biosynthesis V (engineered)";"Rubisco shunt";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I"
XP_015520503.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015513859.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_015519725.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015520785.1	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism"
XP_046595098.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282	"Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_015512290.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_046602519.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_015517246.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015517469.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046595809.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046588453.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015522292.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015519278.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046595043.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_015509754.2	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_046593310.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system"
XP_046597688.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046588241.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015509776.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_015511188.2	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_046602812.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015510858.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046597268.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015519557.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism"
XP_046594994.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015517663.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015516929.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015516511.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046591491.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592838.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015517069.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824	"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis"
XP_046600232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015517590.2	5	Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_046589919.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046587119.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046591169.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015511587.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_046593429.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015524293.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015521700.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_046596137.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_015518918.2	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_015511544.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015522294.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015512771.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046601828.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015515829.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046589847.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015519636.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046589542.1	6	Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712	"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling"
XP_046595219.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_046585869.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015510034.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015514908.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_015512640.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7442	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis"
XP_046593821.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046591050.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015515993.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046597675.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
XP_046590386.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046596921.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015514613.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046599104.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_015520835.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046585913.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_046599398.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691	"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I"
XP_015510918.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_015509952.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015522825.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597050.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_015522158.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015515565.2	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
XP_046587234.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046589095.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046600965.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_046588402.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046595079.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046600581.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015518439.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015510397.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046602216.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591352.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046599816.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046601023.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046591379.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_046589212.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Neutrophil degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046598218.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling"
XP_046595928.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046590390.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015509761.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046591785.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_015524077.2	3	KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_046591996.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015523396.2	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis"
XP_015524709.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046588429.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046592041.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_015511161.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_046589514.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015515501.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015521453.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_015523277.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I"
XP_046593508.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046593195.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_015510719.1	4	Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026	"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_015514958.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592026.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition"
XP_046600877.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046597188.1	11	MetaCyc: PWY-5659;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-3881;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8	"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_046592899.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-5693571;Reactome: R-HSA-5334118;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-110329;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-9610379	"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Nonhomologous End-Joining (NHEJ)";"DNA methylation";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"HDACs deacetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"HATs acetylate histones";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"Cleavage of the damaged pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HCMV Late Events"
XP_046591787.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_046586521.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_015517204.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015511356.2	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_015522098.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015512235.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_046585782.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_015523793.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)"
XP_046601871.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_046591010.1	14	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-500657;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-434316;Reactome: R-HSA-399997;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"PLC beta mediated events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_046586197.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046592667.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-418885	"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"EGFR downregulation";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"Myogenesis";"RHO GTPases Activate Formins";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling"
XP_046587314.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046597690.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_046587930.1	6	Reactome: R-HSA-8986944;Reactome: R-HSA-452723;Reactome: R-HSA-3769402;Reactome: R-HSA-6785807;Reactome: R-HSA-2892247;Reactome: R-HSA-2892245	"Transcriptional Regulation by MECP2";"Transcriptional regulation of pluripotent stem cells";"Deactivation of the beta-catenin transactivating complex";"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"
XP_015521681.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015514589.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046595124.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G-protein activation";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation"
XP_015514482.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080	"Activation of SMO";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)"
XP_046590499.1	30	Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-1170546;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Prolactin receptor signaling";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex"
XP_015513476.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_015510096.2	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_015521255.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046591669.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015516030.1	7	MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483191	"Choline biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC"
XP_046599642.1	6	KEGG: 04070+3.1.3.64;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660517;MetaCyc: PWY-6368;MetaCyc: PWY-6580	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_046586487.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_046589319.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_046585872.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015524968.1	182	Reactome: R-HSA-156902;Reactome: R-HSA-3134975;Reactome: R-HSA-2173791;Reactome: R-HSA-175474;Reactome: R-HSA-5689896;Reactome: R-HSA-110314;Reactome: R-HSA-72764;Reactome: R-HSA-6804756;Reactome: R-HSA-445989;Reactome: R-HSA-72695;Reactome: R-HSA-532668;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-2559582;Reactome: R-HSA-202424;Reactome: R-HSA-2173788;Reactome: R-HSA-5696395;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5357956;Reactome: R-HSA-9604323;Reactome: R-HSA-5675221;Reactome: R-HSA-72702;Reactome: R-HSA-5358346;Reactome: R-HSA-2122947;Reactome: R-HSA-8856825;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-937039;Reactome: R-HSA-8849469;Reactome: R-HSA-8863795;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69541;Reactome: R-HSA-5632684;Reactome: R-HSA-156827;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-9637628;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-6781823;Reactome: R-HSA-8875360;Reactome: R-HSA-5607764;Reactome: R-HSA-72706;Reactome: R-HSA-205043;Reactome: R-HSA-1169091;Reactome: R-HSA-179409;Reactome: R-HSA-5696394;Reactome: R-HSA-180585;Reactome: R-HSA-1236382;Reactome: R-HSA-5205685;Reactome: R-HSA-975110;Reactome: R-HSA-75815;Reactome: R-HSA-1253288;Reactome: R-HSA-4641263;Reactome: R-HSA-9615710;Reactome: R-HSA-9010553;Reactome: R-HSA-9014325;Reactome: R-HSA-450408;Reactome: R-HSA-975957;Reactome: R-HSA-2644606;Reactome: R-HSA-8856828;Reactome: R-HSA-936440;Reactome: R-HSA-5675482;Reactome: R-HSA-8939902;Reactome: R-HSA-937041;Reactome: R-HSA-450321;Reactome: R-HSA-1295596;Reactome: R-HSA-174490;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5689901;Reactome: R-HSA-6782210;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-209543;Reactome: R-HSA-6791226;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9033241;Reactome: R-HSA-5689880;Reactome: R-HSA-2979096;Reactome: R-HSA-5656121;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-937042;Reactome: R-HSA-6782135;Reactome: R-HSA-8876493;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5684264;Reactome: R-HSA-8948747;Reactome: R-HSA-977225;Reactome: R-HSA-912631;Reactome: R-HSA-4641258;Reactome: R-HSA-162588;Reactome: R-HSA-9633012;Reactome: R-HSA-975163;Reactome: R-HSA-9613829;Reactome: R-HSA-5654732;Reactome: R-HSA-450302;Reactome: R-HSA-110312;Reactome: R-HSA-2894862;Reactome: R-HSA-917729;Reactome: R-HSA-2691232;Reactome: R-HSA-2173795;Reactome: R-HSA-68949;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-8948751;Reactome: R-HSA-3785653;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-975144;Reactome: R-HSA-6781827;Reactome: R-HSA-69481;Reactome: R-HSA-2672351;Reactome: R-HSA-8951664;Reactome: R-HSA-110320;Reactome: R-HSA-1169408;Reactome: R-HSA-201681;Reactome: R-HSA-6807004;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9636383;Reactome: R-HSA-9645460;Reactome: R-HSA-209560;Reactome: R-HSA-917937;Reactome: R-HSA-5654726;Reactome: R-HSA-1799339;Reactome: R-HSA-174113;Reactome: R-HSA-69231;Reactome: R-HSA-400253;Reactome: R-HSA-2559585;Reactome: R-HSA-6804757;Reactome: R-HSA-168927;Reactome: R-HSA-5656169;Reactome: R-HSA-6783310;Reactome: R-HSA-5654733;Reactome: R-HSA-5610785;Reactome: R-HSA-937072;Reactome: R-HSA-72649;Reactome: R-HSA-9013507;Reactome: R-HSA-6804760;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-5685942;Reactome: R-HSA-174048;Reactome: R-HSA-5693607;Reactome: R-HSA-2122948;Reactome: R-HSA-9013973;Reactome: R-HSA-2408557;Reactome: R-HSA-5693565;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-901032;Reactome: R-HSA-5696400;Reactome: R-HSA-4608870;Reactome: R-HSA-5357905;Reactome: R-HSA-8866652;Reactome: R-HSA-182971;Reactome: R-HSA-192823;Reactome: R-HSA-3322077;Reactome: R-HSA-936964;Reactome: R-HSA-5689877;Reactome: R-HSA-168928;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-5362768;Reactome: R-HSA-1358803;Reactome: R-HSA-8939236;Reactome: R-HSA-168638;Reactome: R-HSA-8866654;Reactome: R-HSA-2565942	"Peptide chain elongation";"Regulation of innate immune responses to cytosolic DNA";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Assembly Of The HIV Virion";"Ovarian tumor domain proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Eukaryotic Translation Termination";"Regulation of TP53 Activity through Phosphorylation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Formation of the ternary complex, and subsequently, the 43S complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Downstream TCR signaling";"Downregulation of TGF-beta receptor signaling";"Formation of Incision Complex in GG-NER";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of NOTCH4 signaling";"Negative regulation of MAPK pathway";"Ribosomal scanning and start codon recognition";"Hedgehog ligand biogenesis";"NOTCH1 Intracellular Domain Regulates Transcription";"Cargo recognition for clathrin-mediated endocytosis";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"IRAK1 recruits IKK complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of ERBB2 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Stabilization of p53";"Hedgehog 'on' state";"L13a-mediated translational silencing of Ceruloplasmin expression";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Modulation by Mtb of host immune system";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Formation of TC-NER Pre-Incision Complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"CLEC7A (Dectin-1) signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NRIF signals cell death from the nucleus";"Activation of NF-kappaB in B cells";"APC-Cdc20 mediated degradation of Nek2A";"DNA Damage Recognition in GG-NER";"Vif-mediated degradation of APOBEC3G";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Pink/Parkin Mediated Mitophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of ERBB4 signaling";"Regulation of FZD by ubiquitination";"Late endosomal microautophagy";"Regulation of expression of SLITs and ROBOs";"TICAM1,TRAF6-dependent induction of TAK1 complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Clathrin-mediated endocytosis";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of necroptotic cell death";"Regulation of RUNX2 expression and activity";"IKK complex recruitment mediated by RIP1";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Spry regulation of FGF signaling";"Membrane binding and targetting of GAG proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Metalloprotease DUBs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"p75NTR recruits signalling complexes";"Major pathway of rRNA processing in the nucleolus and cytosol";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Peroxisomal protein import";"Ub-specific processing proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Translesion synthesis by POLI";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"IRAK2 mediated activation of TAK1 complex";"Dual incision in TC-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PTEN localization";"Amyloid fiber formation";"Regulation of signaling by CBL";"Degradation of DVL";"Budding and maturation of HIV virion";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Chaperone Mediated Autophagy";"Negative regulation of FGFR3 signaling";"activated TAK1 mediates p38 MAPK activation";"Translesion synthesis by REV1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Orc1 removal from chromatin";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of PTEN stability and activity";"Myoclonic epilepsy of Lafora";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"G2/M Checkpoints";"Stimuli-sensing channels";"Neddylation";"Translesion Synthesis by POLH";"ISG15 antiviral mechanism";"TCF dependent signaling in response to WNT";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Prevention of phagosomal-lysosomal fusion";"Alpha-protein kinase 1 signaling pathway";"NF-kB is activated and signals survival";"Iron uptake and transport";"Negative regulation of FGFR1 signaling";"SRP-dependent cotranslational protein targeting to membrane";"SCF-beta-TrCP mediated degradation of Emi1";"Cyclin D associated events in G1";"Circadian Clock";"Oncogene Induced Senescence";"Regulation of TP53 Degradation";"TICAM1, RIP1-mediated IKK complex recruitment";"Termination of translesion DNA synthesis";"Fanconi Anemia Pathway";"Negative regulation of FGFR4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Translation initiation complex formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of TP53 Activity through Methylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"HDR through Homologous Recombination (HRR)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Processing of DNA double-strand break ends";"Activated NOTCH1 Transmits Signal to the Nucleus";"TICAM1-dependent activation of IRF3/IRF7";"Selenocysteine synthesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"ER Quality Control Compartment (ERQC)";"Dual Incision in GG-NER";"Asymmetric localization of PCP proteins";"Regulation of TNFR1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"EGFR downregulation";"Viral mRNA Translation";"Glycogen synthesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Josephin domain DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2:ERBB3 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NOD1/2 Signaling Pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of PLK1 Activity at G2/M Transition"
XP_015515839.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_015517889.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_015511901.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046589853.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_015520881.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719	"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors"
XP_046586687.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046597266.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046587120.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046596233.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046600549.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046589512.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_015518705.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015519399.1	10	Reactome: R-HSA-72731;Reactome: R-HSA-72649;Reactome: R-HSA-382556;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Recycling of eIF2:GDP";"Translation initiation complex formation";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046598226.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex"
XP_015514168.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015517968.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_015509431.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046589133.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046586088.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046599948.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events"
XP_046594937.1	20	MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-735;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_015517215.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046592535.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046598477.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046592876.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_046596328.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Aggrephagy";"Clathrin-mediated endocytosis"
XP_015521493.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015510586.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592081.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591762.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597836.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046587988.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046588483.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_015520818.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_015523634.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_015515077.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_015518793.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046600957.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015518328.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_015516599.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588916.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046600625.1	6	Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"3-phosphoinositide degradation"
XP_046600209.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046600887.1	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_015518304.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591219.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046592329.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046587122.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015521462.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046597212.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046592782.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046594453.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046595951.1	11	Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection"
XP_015516592.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046587399.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046602266.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015524332.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_015517316.2	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_015516429.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601881.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015522020.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_015511506.1	27	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-5358751;Reactome: R-HSA-8939902;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5339716;KEGG: 04151+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-198323;Reactome: R-HSA-399956;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453	"Thermogenesis";"Human cytomegalovirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"S45 mutants of beta-catenin aren't phosphorylated";"Regulation of RUNX2 expression and activity";"mTOR signaling pathway";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Human immunodeficiency virus 1 infection";"GLI3 is processed to GLI3R by the proteasome";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"B-WICH complex positively regulates rRNA expression";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI3K-Akt signaling pathway";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"AKT phosphorylates targets in the cytosol";"CRMPs in Sema3A signaling";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response"
XP_015520776.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015519107.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_046597271.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046597580.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins"
XP_015510111.2	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_015515568.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"Kinesins"
XP_046599016.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015524638.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046591720.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015524425.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046601161.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination"
XP_015510051.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_015524212.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis"
XP_015511333.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046598225.1	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway"
XP_046596331.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-8856825	"Aggrephagy";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015521000.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_046586533.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_046585749.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_015523189.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_046596248.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046600302.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
XP_046602435.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_015524694.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015524667.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015524232.1	5	Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825	"Neddylation";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis"
XP_046602430.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015513049.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015515317.1	6	Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-69166	"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate"
XP_046596259.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046593665.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_046598906.1	39	Reactome: R-HSA-190375;Reactome: R-HSA-1839122;Reactome: R-HSA-2033519;Reactome: R-HSA-190371;Reactome: R-HSA-5654221;Reactome: R-HSA-5654689;Reactome: R-HSA-5654227;Reactome: R-HSA-190322;Reactome: R-HSA-5655302;Reactome: R-HSA-5654219;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-5654687;Reactome: R-HSA-5654700;Reactome: R-HSA-6811558;Reactome: R-HSA-5654228;Reactome: R-HSA-5655253;Reactome: R-HSA-5654704;Reactome: R-HSA-5654706;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-190373;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-2033514;Reactome: R-HSA-109704;Reactome: R-HSA-190372;Reactome: R-HSA-8853338;Reactome: R-HSA-5654699;Reactome: R-HSA-1257604;Reactome: R-HSA-5654733;Reactome: R-HSA-5654720;Reactome: R-HSA-5654719;Reactome: R-HSA-5654688;Reactome: R-HSA-1839130;Reactome: R-HSA-5658623;Reactome: R-HSA-5654732;Reactome: R-HSA-5654710	"FGFR2c ligand binding and activation";"Signaling by activated point mutants of FGFR1";"Activated point mutants of FGFR2";"FGFR3b ligand binding and activation";"Phospholipase C-mediated cascade, FGFR2";"PI-3K cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR3";"FGFR4 ligand binding and activation";"Signaling by FGFR1 in disease";"Phospholipase C-mediated cascade: FGFR1";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade, FGFR4";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR3";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"FGFR1c ligand binding and activation";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"FGFR3 mutant receptor activation";"PI3K Cascade";"FGFR3c ligand binding and activation";"Signaling by FGFR3 point mutants in cancer";"SHC-mediated cascade:FGFR2";"PIP3 activates AKT signaling";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR4";"SHC-mediated cascade:FGFR1";"Signaling by activated point mutants of FGFR3";"FGFRL1 modulation of FGFR1 signaling";"Negative regulation of FGFR3 signaling";"PI-3K cascade:FGFR3"
XP_046593722.1	14	Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312	"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1"
XP_046586561.1	10	Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383	"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion"
XP_046586303.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_015514736.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046595032.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_015511388.2	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_015511411.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015525000.1	14	MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-3781;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-7254	"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)"
XP_015517872.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514144.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046598580.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586660.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046590120.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_046598371.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015514408.1	18	KEGG: 00401+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115	"Novobiocin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_015512165.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046588296.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046600333.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_046596298.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046598194.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway"
XP_046596487.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_015516446.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_046586635.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_015511496.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)"
XP_046599481.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_015519462.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046589825.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015522547.1	7	Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-166208	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling"
XP_046600743.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046596327.1	9	Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-5627083;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"Clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy"
XP_046602052.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046595924.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046599781.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046589180.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015516163.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046597420.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_046593117.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046590394.1	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
XP_046588921.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046597829.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046587392.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_015521598.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_046593668.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046595251.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046591800.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046593318.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015525110.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046589100.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_046592563.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046600663.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_046588387.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015521371.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_015512820.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046601846.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015510087.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046597157.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046589394.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046593553.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046590800.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_015510752.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015516276.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015510631.2	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046591843.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_015511116.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046598043.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015520491.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-983231	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production"
XP_046595847.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015524846.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046592334.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_046589540.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046602516.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046587063.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046588216.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_015525030.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046595435.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_015510698.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046592440.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015514965.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_015516706.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_046598773.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046602724.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050	"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_046586185.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_015524705.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015521881.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046602236.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046585693.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046593063.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046597932.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046599483.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_015513898.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046586139.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_046596651.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (i) signalling events"
XP_015515553.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046597504.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046597247.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110329	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine"
XP_046592035.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_046593064.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046589690.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046593060.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_046593908.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046598148.1	15	Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-389357;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-1660499;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-912631	"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RET signaling";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"G alpha (q) signalling events";"Synthesis of PIPs at the plasma membrane";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL"
XP_046601476.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015521704.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015517657.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_015524431.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015520779.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_046595577.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597218.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015513358.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046591042.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_046598870.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046596968.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7854	"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_015516191.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_015519175.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807	"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_046588203.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046589243.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_046597679.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_046602241.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046600439.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015521454.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_015517292.1	5	Reactome: R-HSA-446199;Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94	"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis"
XP_015521811.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046590993.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046601527.1	6	KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)"
XP_046597448.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046596020.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046594434.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046592174.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015524708.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046588844.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis"
XP_015514229.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-111367	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046599429.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015521555.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046595737.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046586915.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046589256.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046599858.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015512121.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_015515262.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046601278.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015509573.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046600211.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046600224.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_015520869.1	5	Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_046592474.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_015513289.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_015524321.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046594074.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046595137.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046589494.1	31	Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113	"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis"
XP_046587096.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015521060.2	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_015514425.2	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_015510552.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046586837.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046587679.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oxidative Stress Induced Senescence"
XP_046594864.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015510615.2	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_046600880.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046590422.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015524106.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046599752.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046598607.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046586846.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046592090.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_015518913.2	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_015509151.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046598850.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046586388.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_015509167.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015520527.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046591636.1	9	Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279	"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_015524504.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046585770.1	42	KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-5789;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-7778;KEGG: 00623+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7654;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7007;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-1361;MetaCyc: PWY-7726;MetaCyc: PWY-7656	"Butanoate metabolism";"Glutaryl-coa degradation";"Androstenedione degradation";"Benzoate degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"2-methylpropene degradation";"Toluene degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Geraniol degradation";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Aminobenzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Fatty acid elongation";"Fatty acid salvage";"Phenylalanine metabolism";"Caprolactam degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoyl-coa degradation I (aerobic)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis"
XP_046598556.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_015522480.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism"
XP_015515825.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046593827.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015524352.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes"
XP_046589902.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015523281.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046594452.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Processing of DNA double-strand break ends"
XP_015516769.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015522743.2	8	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation I (yeast)"
XP_046600674.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_015512560.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_015510976.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_046598858.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046588130.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015512345.2	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046593043.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_015516467.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046592532.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_015524136.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046590890.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015515254.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046588324.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_046598453.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046594213.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046587288.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591473.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_015516032.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385	"Plasmalogen biosynthesis";"Synthesis of PC";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Choline biosynthesis I"
XP_015511689.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046587502.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_046594301.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_015523169.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_015521705.2	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_015521054.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046601186.1	6	Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-3000171	"Amyloid fiber formation";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Non-integrin membrane-ECM interactions"
XP_046586972.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046596908.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015509635.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046598222.1	5	Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046589074.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_015522650.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_015512143.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046589958.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_046600261.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046596619.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046600085.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046595018.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_046597303.1	7	MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_015515489.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046590682.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_015519963.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046601799.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046602509.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592387.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046602292.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597125.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046589079.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015524335.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046596037.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046598713.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_015517849.1	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation"
XP_046590767.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046586335.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046596482.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046597123.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_015522076.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery"
XP_046592031.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_046591376.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430	"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling"
XP_046600679.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_015514712.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046591436.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_046598919.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046598625.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723	"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation"
XP_046585882.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015509496.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015518309.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046599342.1	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_015523138.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_015512912.1	16	Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-1660499	"Interleukin-7 signaling";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RET signaling";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"Rho GTPase cycle";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane"
XP_015511856.1	30	Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-2564830;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-167158	"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex"
XP_046597223.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015516241.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046588501.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015514286.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046597460.1	9	Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015519779.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_046598584.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015520461.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_015515424.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_015517332.1	20	Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400	"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Polymerase switching";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER"
XP_015519988.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046595781.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046594987.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046595886.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_015513810.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_046587953.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_015517545.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-5674400	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_015524903.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_046596779.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046587904.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046594300.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_015517688.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_046592693.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_015516121.1	9	MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-7411;Reactome: R-HSA-1483166	"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA"
XP_046593511.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_015522125.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_015518231.1	11	Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942	"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)"
XP_015514990.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_015519086.1	7	KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;MetaCyc: PWY-3841	"One carbon pool by folate";"Metabolism of folate and pterines";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)"
XP_015512387.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_046591272.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046600468.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046597972.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046601913.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046597422.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_015516645.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015518416.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015512850.1	52	Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-73980	"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination"
XP_046595326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046600710.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015516720.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046593551.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_015524827.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046593530.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis"
XP_015515113.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_046598155.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones"
XP_015512125.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_015516837.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046585953.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism"
XP_015524416.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015512580.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046585898.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046599959.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015520591.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046590583.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046587353.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046586700.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046599017.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046597253.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046602803.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015523026.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046589215.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_046591766.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046596120.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046601489.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_046587597.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_015511151.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046594094.1	5	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_015524946.2	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046588398.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046588671.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046593795.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751	"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated"
XP_046591716.1	7	KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4	"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Geraniol degradation"
XP_015521517.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046591961.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046595770.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962	"Polymerase switching";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex"
XP_046587690.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events"
XP_046590361.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_015509397.2	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52	"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism"
XP_046587472.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_046593503.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046591375.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015510420.1	12	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Rho GTPase cycle"
XP_046591984.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_046585716.1	15	Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015514169.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015517445.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015523332.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_015521321.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046598381.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046596302.1	17	Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473	"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint"
XP_015512142.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_046592029.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015513780.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_015510832.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046591280.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046590022.1	14	MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing"
XP_046587952.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_015522562.2	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046601142.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046586746.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_015512843.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046592032.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046587274.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046588092.1	11	Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565	"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants"
XP_046601908.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046598094.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046593714.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046589547.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_046589816.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015511213.2	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_046597812.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046593634.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_015524866.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046600538.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046602210.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046598988.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_015514586.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046586064.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_046593773.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015521644.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_015518980.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_046599287.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway"
XP_015518132.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046595088.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015510140.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_015524613.2	29	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-167158	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex"
XP_015521907.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_015516421.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_015513142.2	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_015520540.2	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046602238.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015514670.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015516335.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015523369.2	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_046598366.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_015519890.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046592428.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_046595811.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046596844.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046598037.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_015514470.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015520983.2	6	MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;Reactome: R-HSA-500753	"UMP biosynthesis I";"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis"
XP_046601622.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_015517330.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046588221.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015521816.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5696400	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER"
XP_046598234.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046595568.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_015513495.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046600967.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046589553.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_046586849.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_015514596.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987	"Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046592694.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_015518738.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_015524226.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046591284.1	29	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6803204;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-3371453;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-349425	"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Stabilization of p53";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_015519529.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736	"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors"
XP_015514110.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046591077.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015516452.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046596184.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015520302.2	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_046597386.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046589718.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_015509820.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway"
XP_046587068.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015510686.1	4	MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism"
XP_046600088.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046588298.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046586613.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway"
XP_046600712.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046593019.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046590425.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046590019.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I"
XP_015524102.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015520149.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_015514738.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046588295.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046591316.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_015521369.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_046598566.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046597508.1	7	KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis"
XP_046601663.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015511128.1	7	KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484	"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_015519785.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015511106.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046594358.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72662	"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046601925.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046594505.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_015522881.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046587307.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600685.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046601191.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046598826.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046590507.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015518601.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015520279.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602797.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046593012.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046592017.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602223.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046601240.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046588774.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015525122.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_046594816.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046601352.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046589714.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_046600675.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_015519245.2	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_046592066.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_046590433.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046587595.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_015524337.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046598786.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046598275.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046596772.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046598139.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_046587977.1	6	KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I"
XP_015523124.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-141430	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_046597044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046599284.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046585707.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588760.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_015522559.2	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_015510999.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015510451.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_046598374.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015523687.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion"
XP_046599859.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015514141.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015513119.2	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046592045.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_046587933.1	6	Reactome: R-HSA-6785807;Reactome: R-HSA-2892245;Reactome: R-HSA-2892247;Reactome: R-HSA-452723;Reactome: R-HSA-3769402;Reactome: R-HSA-8986944	"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional regulation of pluripotent stem cells";"Deactivation of the beta-catenin transactivating complex";"Transcriptional Regulation by MECP2"
XP_015521324.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015516588.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_015521143.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_015509481.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_015515079.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_046599808.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046594457.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046592520.1	33	Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-69656;Reactome: R-HSA-75953	"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation"
XP_015517895.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_015510351.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_015510059.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702	"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Interleukin-1 signaling"
XP_046593519.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046585943.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046601603.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_015512624.1	6	Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317	"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_015521675.2	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_015511899.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_015511669.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015511507.1	27	Reactome: R-HSA-4641262;Reactome: R-HSA-5250924;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-196299;KEGG: 04151+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-198323;Reactome: R-HSA-3371453;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-5358751;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358747;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610785	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"B-WICH complex positively regulates rRNA expression";"Human papillomavirus infection";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"PI3K-Akt signaling pathway";"CRMPs in Sema3A signaling";"AKT phosphorylates targets in the cytosol";"Regulation of HSF1-mediated heat shock response";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"S45 mutants of beta-catenin aren't phosphorylated";"Thermogenesis";"Human cytomegalovirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Regulation of RUNX2 expression and activity";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Human immunodeficiency virus 1 infection";"GLI3 is processed to GLI3R by the proteasome"
XP_046594361.1	12	Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046602002.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_015511731.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_015519558.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046594001.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046587934.1	6	Reactome: R-HSA-6785807;Reactome: R-HSA-2892245;Reactome: R-HSA-2892247;Reactome: R-HSA-3769402;Reactome: R-HSA-452723;Reactome: R-HSA-8986944	"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Deactivation of the beta-catenin transactivating complex";"Transcriptional regulation of pluripotent stem cells";"Transcriptional Regulation by MECP2"
XP_046601185.1	6	Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-3000171	"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Retinoid cycle disease events";"Amyloid fiber formation";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions"
XP_046599850.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046587287.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046600815.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046591560.1	16	Reactome: R-HSA-1250342;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795	"PI3K events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling"
XP_015524955.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015520609.2	10	Reactome: R-HSA-1989781;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391	"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)"
XP_046589211.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Neutrophil degranulation";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation"
XP_046586607.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046598630.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_015509484.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_046595632.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_015512550.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046588681.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_015521527.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046597977.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015509473.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_015521657.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_015521093.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_046599167.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015523697.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046601829.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593758.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-174411	"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere"
XP_015516233.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015519578.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_015510753.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_015522073.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_046598585.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015521972.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046590021.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482788	"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC"
XP_015516940.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046588485.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046586690.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015514140.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046598288.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046599759.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_046586759.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015517078.2	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation"
XP_046592937.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046597703.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015519294.1	31	MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971	"Gondoate biosynthesis (anaerobic)";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_015520588.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046590064.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046599775.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046598772.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015510938.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_046601927.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_015524095.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_046601911.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046593877.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_015521803.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_015511672.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs"
XP_046601491.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_046591759.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046585781.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046598372.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015512451.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015509296.1	9	Reactome: R-HSA-9630221;Reactome: R-HSA-9608290;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-9630222	"Defective NTHL1 substrate processing";"Defective MUTYH substrate processing";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding"
XP_046601300.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046597757.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_015520509.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046594146.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511671.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015523579.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_015518533.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_015510994.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046591383.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015512140.1	52	Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-749476;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-5617472	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046589310.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_015515433.2	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_046592965.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_046590916.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046596914.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046597143.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046594344.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015509897.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_015517456.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-72163	"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Pausing and recovery of HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway"
XP_046602181.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046597881.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046590357.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015512610.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046587211.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046593027.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046594690.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex"
XP_015518868.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046595905.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015517192.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046589550.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_046589824.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046598868.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015510107.2	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_046602146.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514363.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_015517681.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015517462.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_046585760.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_015520929.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046595209.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046598779.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046597079.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046597506.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046593415.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_015509521.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_015516558.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046593319.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046585767.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046595132.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046596401.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015518292.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_015524928.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_015511873.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046595001.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046588304.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_015509492.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046590991.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_015512245.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046599274.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264	"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_046596483.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection"
XP_015517457.2	9	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9608290;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine"
XP_015516346.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046599201.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046597382.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_015519214.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_046598329.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046595151.1	12	MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046594426.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015521597.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015511459.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046602655.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015511983.2	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_046591994.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046591765.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015509752.2	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_046588166.1	8	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015521672.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379	"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events"
XP_046597847.1	18	MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism"
XP_015521153.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_015511863.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046599758.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046600469.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046589570.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_015523076.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046590480.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592060.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046599936.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046599825.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046602512.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015515526.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046591113.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046590388.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation"
XP_046599720.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046598790.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-8876198;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"RAB GEFs exchange GTP for GDP on RABs";"Late endosomal microautophagy"
XP_046588322.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046600885.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_015518662.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_015512802.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046588507.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591486.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046587085.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046594101.1	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
XP_046597155.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046591717.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015515555.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046592745.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015511337.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015512234.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046586199.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015516334.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015521665.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015514297.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_046594047.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046585954.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_046595020.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046586319.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046591588.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046588198.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046596835.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_015519882.1	26	Reactome: R-HSA-5696400;Reactome: R-HSA-8866654;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-4615885;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6804114;Reactome: R-HSA-110320;Reactome: R-HSA-1362277;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397	"Dual Incision in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"SUMOylation of DNA replication proteins";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion Synthesis by POLH";"Transcription of E2F targets under negative control by DREAM complex";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_046598308.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046602514.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046600923.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046591066.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046587165.1	13	MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836	"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism"
XP_046594507.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046592383.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046587138.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_015511517.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046592073.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation"
XP_015524874.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586334.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_046588475.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046594705.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046600278.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_046587439.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_046600661.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046593563.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948	"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants"
XP_015513278.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046591938.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015521257.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046602506.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015511225.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015515903.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis"
XP_015521911.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046593223.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_015517202.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046586626.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015512617.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046592870.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion"
XP_046598621.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580	"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence"
XP_015517679.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_015510711.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588079.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046602336.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046601988.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015512141.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_046587925.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_015513117.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_015511365.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_015520629.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046596211.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_015512413.1	5	KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_015516441.2	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis"
XP_046592336.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_015516377.2	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_046597608.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_015514030.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_046589834.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046589101.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046586485.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_046594227.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046598449.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_015517725.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_046587729.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046589989.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_015509252.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046592335.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_015513355.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-6142	"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_015512837.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy"
XP_046594252.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015509489.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_046593817.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015516945.1	19	MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;Reactome: R-HSA-380270;MetaCyc: PWY-7210;Reactome: R-HSA-380320;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_046601823.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046594051.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046594730.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046595602.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_015522438.2	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_046593843.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046594190.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046599282.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046596560.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_015514742.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046586127.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046601940.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015521353.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015520858.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_015524142.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046587284.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_015513322.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015515132.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_015521005.2	19	Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901	"Platelet sensitization by LDL";"Chylomicron assembly";"Scavenging by Class F Receptors";"LDL remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Chylomicron remodeling"
XP_046596346.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_015519551.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_046588897.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046587179.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_015519217.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046596865.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_015509208.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424	"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling"
XP_046585873.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046599762.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_015523554.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_015521930.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046588178.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601749.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046595099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046589435.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015522017.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_015517363.2	4	KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_015510466.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046587067.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046593643.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046591999.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015510989.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins"
XP_015524492.1	7	MetaCyc: PWY-5074;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4	"Mevalonate degradation";"Synthesis of Ketone Bodies";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies"
XP_015513528.2	57	Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880	"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Interleukin-1 signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases"
XP_015523881.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046597887.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046600615.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_015515496.1	10	KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;Reactome: R-HSA-69205	"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription"
XP_046590940.1	7	KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis"
XP_015510220.2	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation"
XP_046590646.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015523365.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_015511021.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015522606.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046600882.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_015518058.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015512441.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046602079.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046592579.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_015523963.2	15	Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716	"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_015518319.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_015511359.2	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046587066.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_046586038.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_015513964.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_046591286.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693571;Reactome: R-HSA-3371453;Reactome: R-HSA-5693568	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Thermogenesis";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Meiotic recombination";"mTOR signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Nonhomologous End-Joining (NHEJ)";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015511716.2	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046601199.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046599093.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_015523312.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046601538.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046587282.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_015521300.1	10	Reactome: R-HSA-162699;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;MetaCyc: PWY-7661;MetaCyc: PWY-7922	"Synthesis of dolichyl-phosphate mannose";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046601775.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046592302.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015517869.2	15	Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_046596029.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046596644.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046602365.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I"
XP_015519177.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046595788.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046602517.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_015523922.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046596889.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046595234.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015514165.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015512111.2	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046586090.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015511410.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015511361.2	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046593208.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_015520487.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046602086.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-5663	"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_046592840.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015511857.2	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_046596324.1	9	Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083	"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Aggrephagy";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking"
XP_015509838.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046591854.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_015511985.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_046595587.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015520219.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046586130.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046591466.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015516124.2	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_046601269.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_015513611.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_015523850.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_046601708.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015514400.1	18	MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115	"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_015520223.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046587684.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes"
XP_046587954.1	14	MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_015512109.2	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_015511357.2	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046598947.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_015512547.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046586304.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_015515952.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Mitochondrial protein import";"Respiratory electron transport";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species"
XP_046593841.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046592198.1	11	Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801	"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
XP_046593472.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046591388.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015509972.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015523367.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046594684.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046597919.1	6	Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_046591552.1	16	Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1251985;Reactome: R-HSA-1963640;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Nuclear signaling by ERBB4";"GRB2 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_015518128.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046588752.1	10	MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861	"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_046585709.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597922.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046594277.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046594172.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015516203.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046586628.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015512126.2	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015523624.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_046595164.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046598027.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_015523205.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046592173.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046586557.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046592673.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046587598.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046596200.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_046596005.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy"
XP_046592059.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_015511851.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_015523117.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_015523343.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015513800.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046598231.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046591592.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591460.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046592109.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_046585909.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_046601522.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046594263.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046586699.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_015520813.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_046591117.1	4	Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046586910.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015511661.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015521327.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015509266.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_046586473.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_015521037.2	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_015522552.2	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_015516120.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_015517253.1	10	Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459	"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage"
XP_046602711.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046594418.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046601120.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046598290.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015512265.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_015511118.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_015512263.2	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046586912.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046596685.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_046599562.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046586618.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046597126.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046599530.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046586558.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046598810.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_046591252.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_015511067.2	15	Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-1236382;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810	"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII"
XP_015509419.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046597837.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046597966.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015518826.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046594850.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046601950.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_015512606.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046596893.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_046590982.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015520601.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046597415.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_015521437.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_015519041.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046598920.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_015510553.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-201681	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"RHO GTPases Activate Formins";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT"
XP_015519851.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_015515989.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046586376.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015515415.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046597453.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015509217.2	7	MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis I";"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046597839.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015510531.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015523649.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_015509983.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_015519414.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_046601162.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046591313.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_015525083.1	7	Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;MetaCyc: PWY-7158;Reactome: R-HSA-2160456	"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylketonuria"
XP_046591582.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_015517436.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015512792.1	13	Reactome: R-HSA-5689877;Reactome: R-HSA-532668;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-8876725;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895	"Josephin domain DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion Synthesis by POLH";"Aggrephagy";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"HSF1 activation";"ABC-family proteins mediated transport";"Protein methylation";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis"
XP_015511865.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_046594728.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046593352.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis"
XP_015514324.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015517304.2	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_015516274.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046601532.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015521338.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_015518805.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015519520.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046594026.1	7	MetaCyc: PWY-7238;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-5941	"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Neutrophil degranulation";"Starch degradation II";"Glycogen degradation II"
XP_015519720.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_015521455.2	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_046593823.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015514709.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_015519003.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046589800.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046594533.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046587403.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518034.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046594780.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046594359.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling"
XP_046601879.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046588245.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015519034.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP"
XP_046590265.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_015511600.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046601296.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046586474.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046596319.1	9	Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-9613829	"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Clathrin-mediated endocytosis";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy"
XP_015521753.2	7	Reactome: R-HSA-9020265;Reactome: R-HSA-2142691;Reactome: R-HSA-9018896;Reactome: R-HSA-9018676;Reactome: R-HSA-6798695;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661	"Biosynthesis of aspirin-triggered D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of D-series resolvins";"Neutrophil degranulation";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins"
XP_046595233.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593845.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046601904.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_015519764.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015519676.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_015520248.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_015514220.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046592025.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046595677.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion"
XP_046601964.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220	"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_015513969.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015523860.1	14	MetaCyc: PWY-5078;MetaCyc: PWY-5103;MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5057;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108	"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-valine degradation II";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V"
XP_015510509.1	6	MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_015519678.1	9	Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046593820.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_015511715.2	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_015519830.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_046591771.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046601121.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_015511306.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046599626.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_046586510.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046593368.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046592723.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046594079.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015515691.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046589229.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046593028.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015515398.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015517557.1	6	KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;Reactome: R-HSA-1660517;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation"
XP_015513916.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015514591.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046586755.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-350054	"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway"
XP_046592300.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046592234.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_015512736.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_015512309.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046591963.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_015515556.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015523313.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015509986.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046585714.1	7	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_015515306.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production"
XP_015520775.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015511848.1	6	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation"
XP_015517101.1	10	MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-2453864	"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism";"Amyloid fiber formation";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Retinoid cycle disease events"
XP_015521943.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046588051.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_015520628.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046591509.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_015515144.2	11	Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096	"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation"
XP_046599221.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
XP_046599441.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046596991.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015515855.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_015511519.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015516993.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015519143.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046601712.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046595352.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015523424.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_015523208.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046596299.1	17	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"mTOR signaling pathway"
XP_046600448.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046602707.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046588242.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015520189.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation"
XP_046594072.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_015518610.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_046591221.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046596690.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046593726.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046600722.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015511632.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855167;Reactome: R-HSA-983231;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-4661;MetaCyc: PWY-6366;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_015513082.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_015515912.1	11	MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism"
XP_046599374.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_046594394.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_015510701.2	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046593673.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046598696.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_015516791.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015517734.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus"
XP_015515490.2	10	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint"
XP_046599904.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015517888.2	8	MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461	"Rubisco shunt";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P"
XP_046592215.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015510941.2	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046594712.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_015516514.2	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_015522856.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69017	"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6"
XP_046597849.1	18	Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166	"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Synthesis of PA"
XP_015520875.2	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046590647.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046599819.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015510442.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046599085.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015514050.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046597927.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015513707.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046591012.1	14	Reactome: R-HSA-1855204;Reactome: R-HSA-500657;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-4086398;Reactome: R-HSA-434316;Reactome: R-HSA-418217;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-399997	"Synthesis of IP3 and IP4 in the cytosol";"Presynaptic function of Kainate receptors";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Ca2+ pathway";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion"
XP_046592960.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_015511137.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_015514745.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_015521992.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046592674.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_015524695.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046602407.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046594761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602745.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_015518090.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046597986.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046600921.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015522789.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015514687.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_015514326.1	18	MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_046602202.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015514104.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_015517533.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015511262.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346	"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis"
XP_015524051.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_015509512.1	5	MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168	"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)"
XP_015518060.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_015524771.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_015524409.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046602801.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046597185.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-3861;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_046600472.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046585737.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046598953.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046597581.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_015523487.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015514506.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015514318.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046591804.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046598408.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046598192.1	10	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"RSK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015523795.1	7	KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_015517852.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_015522582.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046602306.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015512498.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015523085.1	15	Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_046600399.1	24	Reactome: R-HSA-165158;Reactome: R-HSA-2871837;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Activation of AKT2";"FCERI mediated NF-kB activation";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs";"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046598459.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015524943.2	19	Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888	"Scavenging by Class B Receptors";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class A Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"VLDL assembly";"LDL remodeling";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly"
XP_046594947.1	14	MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation"
XP_046588872.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015517331.2	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015523827.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_015509836.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015510363.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_046597146.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046587795.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_015511910.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015523845.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015513502.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046600582.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046587402.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046599776.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_015513669.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015518528.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015521990.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_015515430.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015521219.2	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_046591944.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015514603.1	12	Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801	"Glycogen synthesis";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Sucrose biosynthesis II";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)"
XP_015516302.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_015511399.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046592926.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_015523819.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046600623.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_046600222.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046586332.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046587144.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586712.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_015513170.1	6	Reactome: R-HSA-8868766;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion"
XP_015512417.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015512123.1	3	Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4	"Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_015524350.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168	"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015518389.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046589323.1	31	MetaCyc: PWY-5367;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-7858;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558	"Petroselinate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_015524622.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_046586070.1	14	Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-7782;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4	"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Glycerolipid metabolism";"Synthesis of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_015516942.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_015518801.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_015510771.1	17	MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2	"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Aflatoxin biosynthesis"
XP_046600380.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015509448.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046585741.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046600388.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_015513980.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_046597716.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588678.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_015516833.1	7	MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_046592228.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015518979.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_046594660.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046595387.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046588459.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046586046.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_015512070.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046591660.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046585759.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_015510434.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046596618.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015517820.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015519670.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_015513861.2	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-7394	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin II"
XP_015515781.2	31	MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367	"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis"
XP_015523002.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015510751.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046592590.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)"
XP_015524966.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_015511129.1	7	MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Methane metabolism"
XP_046588950.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_046594908.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046588087.1	25	Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8951936;Reactome: R-HSA-8941332;Reactome: R-HSA-8931987;Reactome: R-HSA-8935964;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-8939242;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8951911;Reactome: R-HSA-8941326	"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates expression of components of tight junctions";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates bone development"
XP_046599488.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015518915.2	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_046599178.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046586778.1	9	MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;Reactome: R-HSA-70171	"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis"
XP_015517616.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015511520.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046599427.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046587971.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_015516227.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593289.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046593865.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046586229.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation"
XP_046598254.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046594536.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-912694;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-877312	"Costimulation by the CD28 family";"Regulation of IFNA signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"PECAM1 interactions";"Platelet sensitization by LDL";"PD-1 signaling";"Interferon alpha/beta signaling";"Regulation of IFNG signaling"
XP_046598535.1	12	KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-6978;MetaCyc: PWY-5857;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5856;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-6708	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_046593819.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015521166.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-5667	"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_046594815.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046589552.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_015514981.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_015514244.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_015517118.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046599399.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_046591700.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_015516316.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015511897.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046595901.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015523191.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_015521083.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015510890.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046589127.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982	"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046586729.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015512061.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015518119.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015519719.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_015522341.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones"
XP_046596965.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_046592199.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046595055.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_046590483.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic"
XP_015510651.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015519305.1	3	KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_015510731.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046600715.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_015511403.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-3661;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1	"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism"
XP_046586841.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015517633.1	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;MetaCyc: PWY-6891	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)"
XP_046586195.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046594249.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015510530.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_046601060.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046587398.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046596294.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_015513961.1	13	MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-7254	"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)"
XP_046586387.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046586758.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_046602212.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015510362.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_015511498.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_046596022.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_015509638.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046598261.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046588947.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015512189.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_015514299.2	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_046595947.1	11	Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection"
XP_015510734.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015524525.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_015514001.1	10	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-5667	"Synthesis of PA";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_046597081.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_015516304.1	10	KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276	"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"
XP_015515560.2	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen degradation";"Collagen chain trimerization";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_046600095.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046587741.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046586074.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046600464.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_046593717.1	8	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection"
XP_015514375.2	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046602256.1	13	MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_015522066.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046593179.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046587326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015522327.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015513021.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015517378.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046595893.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046594436.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046595054.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events"
XP_015514193.2	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046597189.1	11	KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-5659	"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis"
XP_046599569.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015523225.1	9	KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)"
XP_015510204.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_046598838.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-9609690	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events"
XP_015516655.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015518418.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046586794.1	15	Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571	"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)"
XP_015510853.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046601831.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591268.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046595138.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_015512819.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046591685.1	14	MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7589	"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_015519111.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_015522207.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_015520962.2	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_046590762.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046587503.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_015512745.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046598806.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_015511875.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046588059.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015522095.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015521053.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_015518715.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_015523193.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015517371.2	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_046598610.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_015512340.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046594456.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046602703.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_015518798.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_015520589.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015524078.2	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_046597456.1	9	Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015520695.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046597838.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection"
XP_046590765.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046587117.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046590029.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_046585747.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_015517063.1	52	Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-72163;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Major Pathway";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression"
XP_015513585.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046593855.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015509944.2	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046598539.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-5621575;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"PPARA activates gene expression";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes"
XP_015512344.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_015509985.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046599261.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015510353.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes"
XP_046586723.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015515713.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046598710.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046594867.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_015515165.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569	"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046597733.1	11	KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_015514176.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046592311.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046592403.1	5	KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841	"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)"
XP_046597848.1	18	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Anandamide biosynthesis II"
XP_046598727.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_015514130.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046592227.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015513876.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046597747.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046599188.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046600800.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_015519777.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_046591591.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015512153.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046598035.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046585739.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation"
XP_046595845.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015525016.1	6	KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism"
XP_046601364.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_015511332.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046601609.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015518428.2	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015513005.2	9	Reactome: R-HSA-2426168;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha"
XP_046585755.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046601589.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015523475.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_015519391.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046596659.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_015519054.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015522910.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046597389.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046597350.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046593759.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-111465	"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins"
XP_015511826.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9609690	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events"
XP_046594504.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_015522822.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046588902.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046597142.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015522777.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_015514735.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046587089.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046599627.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_015519207.2	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015515861.1	5	KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;Reactome: R-HSA-389661	"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation"
XP_046594516.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_015522012.2	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_015512853.1	4	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516	"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin"
XP_015518320.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725	"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_015509712.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046601554.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015515163.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"Regulation of MECP2 expression and activity"
XP_046600331.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046599204.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046600203.1	4	Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_046586204.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046585862.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015516507.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_015515659.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_015522505.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046590801.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_046593860.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046602296.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046598816.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046588085.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046591581.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_015518758.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_015515084.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_046586523.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015524623.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046587438.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-170660	"Purine metabolism";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway"
XP_015524470.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046600303.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_015518012.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_015513504.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_046598577.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046600733.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046593030.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015513305.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390450	"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC"
XP_046586447.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046587298.1	5	MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_015522706.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015523799.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_046597152.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046590889.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046590026.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788	"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC"
XP_015512243.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_015518508.2	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_015514575.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046599015.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046598191.1	10	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway"
XP_015510522.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_015521935.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015511928.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046602007.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015520921.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046600470.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046599283.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046599598.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015514488.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_046587474.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046594788.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015512365.2	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_015513608.1	7	MetaCyc: PWY-7854;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7295;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"D-xylose degradation IV";"L-arabinose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism"
XP_046588406.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_046601975.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046597583.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015511136.1	22	MetaCyc: PWY-7592;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-5353;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7727	"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_046591644.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015516159.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046590645.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015522508.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046598309.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046596684.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1"
XP_015522391.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015511604.1	6	Reactome: R-HSA-1483148;MetaCyc: PWY-5668;Reactome: R-HSA-1483166;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269	"Synthesis of PG";"Cardiolipin biosynthesis I";"Synthesis of PA";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II"
XP_015524895.2	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046588080.1	14	Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046587590.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323	"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling"
XP_046594240.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015512336.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_015521057.2	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_046596963.1	20	MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7726	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_015521251.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_015519404.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation"
XP_046596940.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046595021.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046595089.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046596019.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046600467.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046597331.1	6	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381426	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046589104.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046589815.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_015522344.1	18	MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_015515682.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_015524814.2	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_015519908.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046588302.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_046593116.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046596634.1	4	KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_046590071.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015518190.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_015513275.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_015522575.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5856;Reactome: R-HSA-2142789	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
XP_046599478.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_015513944.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_046587322.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015524440.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_046595784.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015517244.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015513910.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046601265.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_046600263.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_015521368.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_046585750.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_046590119.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046597697.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015513900.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046595904.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046589306.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046597772.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_046591546.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_015519718.1	4	KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046599472.1	3	Reactome: R-HSA-5576890;Reactome: R-HSA-5576893;Reactome: R-HSA-1296072	"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase";"Voltage gated Potassium channels"
XP_015513779.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_015510668.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046601524.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation"
XP_046587009.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046601716.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046596183.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046595735.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046591478.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_015514552.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes"
XP_046601555.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046593276.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015512851.1	13	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3	"Folate transformations I";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_046597691.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_046599003.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046588219.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_046597147.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015509930.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046595433.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046602709.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_015519044.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_015517452.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046601553.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046602228.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046598551.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046599177.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015510244.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046590576.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046590718.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046601443.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_046599490.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046590575.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_015514592.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046601346.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046588305.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_046587100.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015510587.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046601251.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046602085.1	6	MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151	"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046587479.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_015523920.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_015520086.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046585727.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046591485.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046600864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046591648.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_015521125.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046600297.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_015510790.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015518141.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_046601880.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015520312.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_046594224.1	18	Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925	"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PG"
XP_046589549.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_015521042.1	5	Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis"
XP_046598373.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015521405.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046591801.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046592085.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046598705.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046592450.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046592259.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600540.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046596964.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7574	"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_046589523.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046597947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015520830.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015514391.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_015524815.2	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_046602750.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046592111.1	7	Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046589587.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015515377.1	3	Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985	"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose"
XP_046599250.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-6922;Reactome: R-HSA-70635	"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"Canavanine degradation";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle"
XP_015513387.1	7	MetaCyc: PWY-7625;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11	"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Inositol phosphate metabolism"
XP_015509526.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_046598498.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_046594508.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_015512397.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895	"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis"
XP_046588134.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046591988.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046596040.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins"
XP_046599087.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046586140.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_015512232.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046592042.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015515303.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015509194.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046602084.1	6	KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_015522265.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046599242.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046588898.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_015516392.1	6	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport"
XP_046598496.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_046593062.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_015509984.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046594170.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015515581.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046599086.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015523945.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046595637.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_015511690.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_015520887.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-936837	"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases"
XP_015516186.2	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_015521234.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046593745.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_015512045.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_015509331.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-69601	"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Hedgehog 'on' state";"Interleukin-1 signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_046589166.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_015510815.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046592564.1	6	MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046593507.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046589121.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_015524643.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702	"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Hedgehog 'on' state";"Interleukin-1 signaling"
XP_046587527.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_015510844.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_015513290.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046591798.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148	"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015513084.1	6	Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046591512.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046597256.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046586075.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015515360.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015516976.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_015515698.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_046599385.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046591712.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046597201.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_046595368.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046593175.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_015517964.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA"
XP_015512233.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_046586463.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase"
XP_015524141.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015511061.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046596203.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015513962.1	7	Reactome: R-HSA-70635;MetaCyc: PWY-6922;MetaCyc: PWY-46;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1	"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Canavanine degradation";"Arginine and proline metabolism";"Urea cycle";"Arginine biosynthesis"
XP_046598788.1	6	Reactome: R-HSA-8876198;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"RAB GEFs exchange GTP for GDP on RABs";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_015522180.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046595232.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes"
XP_015520579.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015522827.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046595816.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_015510660.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046588036.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_015512720.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597971.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015510437.2	8	Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_046602739.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015522325.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-445144	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Synthesis of PC";"Signal transduction by L1"
XP_015511839.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046590563.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_015524001.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_015510861.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046598242.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046589359.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_015522219.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling"
XP_015513972.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046599912.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046600868.1	52	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-5578749;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-167290	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Pausing and recovery of HIV elongation"
XP_015512534.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_015520654.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015519724.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_015513572.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015523914.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046601492.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_015510054.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046585897.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046598434.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046598787.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-8876198	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"RAB GEFs exchange GTP for GDP on RABs"
XP_015514307.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_015519765.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046599392.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_015520550.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015510966.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015513050.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046598405.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_015518237.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046596630.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_015509904.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_015515216.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046598909.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV"
XP_015514458.1	18	MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_046596325.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Aggrephagy";"Clathrin-mediated endocytosis"
XP_015523757.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046600264.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_015524833.1	9	Reactome: R-HSA-9656255;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-5649702;Reactome: R-HSA-9657050;Reactome: R-HSA-110329	"Defective OGG1 Substrate Binding";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine"
XP_046598591.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046594581.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_015514258.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046599484.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_015518032.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_046597423.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046596484.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015517182.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_015512558.1	9	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69017	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6"
XP_015513020.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015509176.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes"
XP_046596318.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880	"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Aggrephagy";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases"
XP_046601965.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_046594949.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_046590408.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015513870.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_046586143.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_015519355.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046592201.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046596348.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046596471.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_015519968.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015509588.2	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046591579.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_015511404.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1	"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism"
XP_015517002.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_015512836.2	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046600681.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046591590.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046589214.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Platelet degranulation";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_015514259.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046602055.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046600522.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_015524541.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046601781.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015519174.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Other glycan degradation"
XP_046589995.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015520704.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015524030.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046601735.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046585813.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_046591580.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046596992.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602235.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046588458.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_015518577.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015520490.1	32	Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167158	"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex"
XP_015524025.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597482.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046591254.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_015523334.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046597937.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_015515557.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046593577.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001	"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"RAF/MAP kinase cascade"
XP_015525084.1	7	KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;MetaCyc: PWY-7158	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"L-phenylalanine degradation V"
XP_046594512.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046590687.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_015519539.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_046588128.1	7	Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylketonuria";"L-tyrosine biosynthesis IV";"Folate biosynthesis"
XP_046593017.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_015514135.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046588645.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015509402.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_015516358.2	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046588400.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046601680.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015511989.1	8	MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_015517091.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046602345.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_046588554.1	12	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"mTOR signaling pathway"
XP_015516221.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_015514867.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_046586869.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046588772.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015512039.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_015513701.2	5	Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_046596606.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046586627.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_015519533.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015510767.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_015512190.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511623.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046592797.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046590481.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594859.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046589654.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015524620.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015514200.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015510653.2	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_015522992.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"HCMV Early Events"
XP_046592062.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_015520303.2	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046597883.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015518082.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_015513125.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_015519585.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_015523675.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046586620.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046588802.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046591549.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_015512734.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046587320.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046591046.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046591969.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046590266.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046597310.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046586567.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046596607.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_015518235.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046598835.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046593132.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_015516725.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_046597214.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046591962.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_015524158.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046597160.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046593711.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046598420.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015509619.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_015521041.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_015523822.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046588427.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046587042.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046600461.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046600017.1	3	Reactome: R-HSA-168928;Reactome: R-HSA-70350;Reactome: R-HSA-9639288	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism";"Amino acids regulate mTORC1"
XP_046594117.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046590161.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015517686.2	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046601681.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046598980.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046599479.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046599281.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046600418.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046600295.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046598538.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-5621575;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508	"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Estrogen-dependent gene expression";"PPARA activates gene expression";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_046596838.1	8	MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage"
XP_015523266.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_015517190.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046591308.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046596949.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_015516941.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_015517620.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_015518897.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046591584.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046598792.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015515904.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_046598784.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046593858.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046591360.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_015511966.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046590216.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_015523602.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046588217.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_046593302.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046595439.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046598364.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046594039.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046600442.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_015510551.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_046587789.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046594932.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046592494.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015523775.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_015514101.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046587101.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046594421.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046588301.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046588232.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_015522010.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_015524209.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_046588675.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_046599464.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046587035.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_015520718.2	7	KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046596270.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597610.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046589083.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046599189.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046595236.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015514954.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046586186.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046597885.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046586830.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_046587793.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046591666.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046598540.1	26	Reactome: R-HSA-5617472;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_046591687.1	5	Reactome: R-HSA-4793954;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-532668	"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046598709.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046598144.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_015516732.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046591946.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046588757.1	17	Reactome: R-HSA-9616222;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-113501;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300	"Transcriptional regulation of granulopoiesis";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046598852.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046598241.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015514175.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046596261.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_015524876.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_015520778.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046600107.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_015522396.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046588548.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_046591206.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015509219.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788	"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling"
XP_046595491.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2	"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism"
XP_046592777.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046595581.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596322.1	9	Reactome: R-HSA-9613829;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-5627083;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"Clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy"
XP_046589599.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015517153.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046594547.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_015509848.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046593814.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015519387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015524361.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046595230.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_015521709.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015509777.1	8	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046587142.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_015519350.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594248.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046590512.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_015514874.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046586089.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015510508.1	7	MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_046587405.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"T cell receptor signaling pathway"
XP_046589216.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"Platelet degranulation";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
XP_046602277.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_046592936.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046595129.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_046588843.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897	"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes"
XP_015522267.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046602220.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015514389.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046602340.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_015510151.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_015509953.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046592959.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046588433.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)"
XP_046590353.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046598778.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_015522200.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046595736.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015514517.2	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_046590276.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046601588.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015520217.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046588755.1	10	KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11	"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism"
XP_046597874.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046599970.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015518019.1	11	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046590186.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015511545.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_046599817.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046587092.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_015521677.2	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_015518242.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_015512566.1	14	KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Synthesis of PC";"Ether lipid metabolism";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I"
XP_015520934.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_015524375.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_015511944.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046592961.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_015514845.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_015510740.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046588917.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_015522078.1	16	Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-983168	"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015516709.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_046598384.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015514173.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046596181.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_046591171.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015524890.2	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046602611.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015518929.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_015518142.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015514296.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_015524274.1	4	Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_015521514.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015511515.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046602147.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015522230.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_015517604.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046594034.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354	"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Lipophagy"
XP_015519732.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046597261.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015521085.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015523391.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_046586625.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046597351.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046602182.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_015522991.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_015518932.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046590574.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation"
XP_015510444.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046586573.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_046595431.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046585886.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015510465.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046599963.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046599083.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015522545.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046585761.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_015521248.2	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046594180.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046601158.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_015521783.2	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046591357.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046597830.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_015511409.2	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046587404.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-69231	"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1"
XP_046592146.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015516865.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046585911.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-432722	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_046598825.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_046592921.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046586570.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_015515892.1	4	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_015518494.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785	"Degradation of AXIN";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome"
XP_046601198.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_015509778.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_015521662.2	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_046594233.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015512632.2	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_015516631.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046595851.1	12	Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"Macroautophagy";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes"
XP_015510996.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046594216.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_015516189.2	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046588392.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015521906.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046594464.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_015514139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592877.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046588690.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046599968.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015524060.2	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046595585.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015522241.2	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_015516156.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_015515401.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_015515804.1	6	MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238	"Glycogen degradation II";"Starch degradation V";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II"
XP_046601629.1	10	MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_046600504.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015510774.1	17	MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism"
XP_015518860.1	4	Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_015517710.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046596632.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_015514289.2	33	Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-69656;Reactome: R-HSA-167246;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_046590482.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046586824.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
XP_046602531.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046597265.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046598794.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046586565.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_015512874.2	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_046598255.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046591285.1	29	Reactome: R-HSA-5693579;Reactome: R-HSA-6804757;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6803204;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693571;Reactome: R-HSA-3371453;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565	"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Thermogenesis";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Meiotic recombination";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Nonhomologous End-Joining (NHEJ)";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046594531.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046600541.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046589386.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_015515886.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_046591277.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_015520856.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events"
XP_015520942.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046599988.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046591952.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046591032.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015515278.2	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_046597709.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046595757.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046593029.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015511329.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046598791.1	6	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-8876198	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"RAB GEFs exchange GTP for GDP on RABs"
XP_015511514.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046595391.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046600499.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046597489.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_015524584.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_015514720.2	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion"
XP_015515761.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_015511858.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_015515636.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046602721.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_015510209.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015509447.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_015515981.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015509220.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8863795	"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of ERBB2 signaling"
XP_046595938.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_015519345.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_015512751.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_015522218.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176	"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of AXIN";"Neddylation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_046602630.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_015517175.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_015521162.2	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046594346.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046592484.1	17	Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-5743	"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Carnitine metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle"
XP_046597592.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-561	"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_046587736.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046594513.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046590043.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015518647.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597956.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046593683.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_015510570.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_015514448.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_015524340.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_015510109.2	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_015518649.1	8	MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_015511014.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046593141.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829	"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy"
XP_015511759.2	4	Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975138	"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_046594868.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_015512075.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046602466.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_015511732.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046592148.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046597479.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015518396.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046593176.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046597920.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;Reactome: R-HSA-5083632	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_015516082.1	14	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_046587057.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015520851.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_015512154.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015509634.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015510549.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_015520750.2	11	Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-110314	"DNA replication initiation";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046596265.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015513573.1	30	Reactome: R-HSA-5607764;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-1170546;Reactome: R-HSA-2894862;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-68949	"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Downstream TCR signaling";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Orc1 removal from chromatin"
XP_046587601.1	32	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167290	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Pausing and recovery of HIV elongation"
XP_046600213.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046598152.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1"
XP_015516711.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046592023.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046600215.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046599623.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046594251.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015522155.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046593016.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_015520568.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_015511893.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_015522205.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015519615.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_015510960.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046602012.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046593414.1	13	MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)"
XP_046590979.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015515527.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_046589715.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046588901.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015524927.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046597132.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_015516020.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046600260.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_015510167.2	10	MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-4661	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_015522348.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015523909.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046587012.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_015520113.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046593766.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752	"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated"
XP_015510398.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046588570.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_015510550.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_015519708.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380972	"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_015521771.2	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_046587812.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046595673.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Galactose metabolism";"Other glycan degradation"
XP_046592117.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046599566.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015514764.2	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046597282.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046587212.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046590028.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4	"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_015519799.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-373753	"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Nephrin family interactions"
XP_046593764.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046587061.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_015516962.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_015516295.1	17	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_015518746.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_015513251.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046594886.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015516553.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015523415.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046588386.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_015517211.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_046592836.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015520928.1	40	Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5578749	"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs"
XP_015520414.1	32	Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_015510026.2	5	MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
XP_046588547.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_046602247.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046590122.1	5	MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I"
XP_015522196.1	3	KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism"
XP_015518745.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_015510032.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046586586.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015519067.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514288.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_046589814.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_046588434.1	7	KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism"
XP_015513315.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015514714.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange"
XP_015522201.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046589192.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015517610.1	10	KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-8004;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
XP_046594789.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046601228.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_015518417.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015511068.2	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046586738.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046602275.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046589186.1	13	Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2871809;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;MetaCyc: PWY-8052	"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"DAP12 signaling";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated Ca+2 mobilization";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis"
XP_015514071.2	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_015518321.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_046591051.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514080.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide"
XP_015521616.2	3	MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3	"Urate conversion to allantoin I";"Purine metabolism";"Caffeine metabolism"
XP_015513733.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_046597150.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046600576.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015513284.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046599260.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_046595324.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597759.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_015524767.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015509437.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046590426.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046589845.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046601776.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015512078.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046600918.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015518110.1	24	KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-2730905;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921	"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activation of AKT2";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"RSK activation";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Downstream TCR signaling";"Integrin signaling";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation"
XP_015518885.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046600686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512642.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015510494.2	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718	"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes"
XP_015511805.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046594846.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046596648.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_046587036.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_046598352.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015514686.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046587692.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_015524956.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_015520221.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_015512037.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_015522133.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_015516590.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-428930	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G-protein activation";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor"
XP_046590684.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046593491.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-111932	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion homeostasis";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB"
XP_046599774.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_015522022.2	5	Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233	"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway"
XP_046591548.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615	"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation"
XP_015517732.2	17	Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_046593847.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015514018.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015515531.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015522635.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_015510020.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_015510805.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015516799.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_046602014.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046592130.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_046589163.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046593497.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046586096.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015512218.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046592732.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046597951.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046596182.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015517839.2	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_046600086.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015512821.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015518535.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615;Reactome: R-HSA-1474151	"Folate biosynthesis";"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046596598.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046594023.1	7	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737;Reactome: R-HSA-6798695	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Starch degradation V";"Neutrophil degranulation"
XP_046601250.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591459.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015516556.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046589082.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8055	"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis"
XP_015514496.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046597518.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046586196.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy"
XP_046591056.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_015510704.2	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_015514245.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596185.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_015510980.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046595384.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046599105.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046601836.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015509261.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046602756.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046597459.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015519986.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046600793.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_015517726.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_015516934.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_015512663.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_046601628.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_046599601.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_015520458.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_046600947.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_046599103.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046602805.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015510281.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_015511870.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_015513321.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046590477.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015521904.2	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_015510628.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_015520011.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046594731.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046594260.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046595031.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_015521560.1	13	KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"DAP12 signaling";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_015510326.1	14	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_015512393.1	33	MetaCyc: PWY-6587;KEGG: 00260+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00625+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7013;KEGG: 00010+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5078;MetaCyc: PWY-7111;KEGG: 00982+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-6313;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-6342;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-7798;MetaCyc: PWY-7118;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-5751;MetaCyc: PWY-7396;MetaCyc: PWY-1801;KEGG: 00071+1.1.1.1;KEGG: 00592+1.1.1.1	"Pyruvate fermentation to ethanol III";"Glycine, serine and threonine metabolism";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Chloroalkane and chloroalkene degradation";"L-tryptophan degradation V (side chain pathway)";"Tyrosine metabolism";"L-valine degradation II";"(S)-propane-1,2-diol degradation";"Glycolysis / Gluconeogenesis";"Naphthalene degradation";"L-methionine degradation III";"L-isoleucine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"Drug metabolism - cytochrome P450";"Ethanol oxidation";"Serotonin degradation";"Methane metabolism";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450";"Acetaldehyde biosynthesis I";"Protein S-nitrosylation and denitrosylation";"Chitin degradation to ethanol";"L-leucine degradation III";"Salidroside biosynthesis";"Phenylethanol biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Formaldehyde oxidation II (glutathione-dependent)";"Fatty acid degradation";"alpha-Linolenic acid metabolism"
XP_015524587.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015519353.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046598404.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_015519856.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_046591789.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_015522754.2	24	Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-190840	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_015516288.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046602645.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046600863.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015522247.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046594726.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046586835.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046600983.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_015518363.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046596466.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046601694.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015515382.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015509630.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_015515534.2	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046599760.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015513936.2	5	Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_015515716.1	18	Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925	"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG"
XP_015511548.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_015522249.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_015511108.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015523171.1	18	Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167238	"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_046595634.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046601958.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046585730.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046587346.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138	"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_015521742.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_015510373.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046599428.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015520426.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174430	"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Telomere C-strand synthesis initiation"
XP_046594550.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046588845.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism"
XP_015510560.2	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941	"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses"
XP_015524032.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_015517721.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)"
XP_046593861.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046599563.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015520870.1	5	KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I"
XP_046600142.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015522641.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_015519359.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046593522.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017	"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_015513316.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_046592304.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_046587599.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_015520754.2	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_015518125.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_015511123.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_046594416.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046591525.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046597818.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046595687.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_015520656.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046591161.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046594930.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015517671.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046601149.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_015518228.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046586549.1	6	Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110357	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1"
XP_046597568.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015519292.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046587305.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015510112.2	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_015523325.1	34	Reactome: R-HSA-167246;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-69202;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-73779;Reactome: R-HSA-6782135	"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin E associated events during G1/S transition";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER"
XP_046591896.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_046587323.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015515730.2	6	Reactome: R-HSA-5368286;MetaCyc: PWY-6367;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"Mitochondrial translation initiation";"D-myo-inositol-5-phosphate metabolism";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_046591612.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_015524400.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins"
XP_046602178.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_015520484.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_046589258.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_015522299.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_015521758.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_015511229.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046593781.1	15	Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751	"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated"
XP_046601709.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_015512859.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69166	"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate"
XP_046585904.1	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_046596260.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046594931.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015517555.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015516100.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046591040.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593014.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046593971.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046597197.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046602301.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046602752.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_015521924.2	18	Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053	"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Anandamide biosynthesis I";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II"
XP_015514403.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046599019.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046593277.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_015509789.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_015511598.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046588771.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_015521817.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_015509910.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046598976.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046590059.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046596628.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_046597264.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046594929.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_015513593.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_015515988.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_015523361.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015513041.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015518545.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_046592591.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046587409.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_015520054.2	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046600296.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_015523524.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046594711.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_015516199.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_015519183.2	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046598706.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_015520637.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046593410.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_015518917.2	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_015522126.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_015520763.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046589522.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_015511990.1	8	MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_015514399.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046591761.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_015523309.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046590020.1	14	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Ether lipid metabolism"
XP_046598291.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_015519744.2	13	Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956	"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046589803.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046587911.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046593126.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046586215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015522565.2	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015523658.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_015520450.2	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_015515030.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046594688.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress"
XP_015511696.2	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046598259.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046597153.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_015516768.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046600949.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015519698.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046591159.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015522694.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046595963.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046587497.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046595898.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046597595.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046599152.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_015511765.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046595798.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046588432.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_015516828.2	8	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288	"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Amino acids regulate mTORC1"
XP_046587309.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046594934.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046586611.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_015513431.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174411	"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere"
XP_046592497.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_046591849.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046597174.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638	"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway"
XP_046586688.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046589844.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015512289.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_046596179.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_046592232.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046597725.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046594247.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046591472.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_015521089.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046597017.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046597928.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_015520147.2	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_015509449.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046594723.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_015509631.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015524746.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046594621.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015513835.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_015509698.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_046594215.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_015523360.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_015519170.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046590549.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015511933.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046588397.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015511148.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_015516992.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046590025.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788	"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC"
XP_015509584.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_015513057.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_015512427.2	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046591842.1	8	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015514641.1	12	KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-6932	"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Purine metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenate reduction"
XP_046590485.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190861	"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Gap junction assembly"
XP_046586372.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046594620.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015522132.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_015518130.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046585927.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species"
XP_046597873.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_015514642.2	12	MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4	"Sulfite oxidation III";"Purine metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Sulfur metabolism";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfur metabolism";"Monobactam biosynthesis"
XP_015522719.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_015515315.1	19	MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;MetaCyc: PWY-5172;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5	"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Neutrophil degranulation";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)"
XP_015510316.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_015519721.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_015509339.2	15	Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756	"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_015519756.1	10	Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-3821	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification"
XP_046585710.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591589.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046594214.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046594241.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015512823.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_046599794.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_015515028.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_015524385.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046591004.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046592701.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046585977.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_015510097.2	6	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381426	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_015518964.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046598736.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046591404.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046600583.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046588514.1	8	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins"
XP_046586970.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046599818.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046591587.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046587397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602486.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046592250.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046595815.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015510879.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168325	"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis"
XP_015523525.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046591087.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_015520087.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046602437.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_015515018.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_015522467.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_046595949.1	11	Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection"
XP_046601341.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends"
XP_015516116.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015522290.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046595636.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_046596369.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_015521215.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015513674.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-2467813	"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids"
XP_015509368.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_015523046.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046598827.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_015518908.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_015513300.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046593272.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046587291.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046595999.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046592400.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_046597283.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046600511.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046593413.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384	"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_046593696.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_015509148.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046600510.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015517699.1	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway"
XP_046586507.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_015511422.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046597203.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015514915.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_015514128.1	3	Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807	"Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling"
XP_046594809.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015514056.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_015518680.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_046591764.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046591873.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_015512956.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_015520871.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046592957.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_015519275.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_046598837.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910	"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs"
XP_046599474.1	3	Reactome: R-HSA-5576890;Reactome: R-HSA-5576893;Reactome: R-HSA-1296072	"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase";"Voltage gated Potassium channels"
XP_015521390.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015517821.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015516017.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_015517945.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_015523711.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046586714.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_015523538.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046602246.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015509624.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015511196.1	14	MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;Reactome: R-HSA-75876	"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_015510554.1	7	Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-201688	"Degradation of DVL";"RHO GTPases Activate Formins";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL"
XP_015523699.2	7	Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_015523518.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046599917.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046588091.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993	"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling"
XP_046597678.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046593479.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_015519907.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_015516445.2	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046593802.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716	"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_015510477.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_015514739.1	8	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046586518.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046594851.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046588243.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015520787.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_015512342.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190861	"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Gap junction assembly"
XP_046593478.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ion homeostasis";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046594813.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015510075.2	6	Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3	"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_046594363.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling"
XP_046589493.1	31	Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-7746;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-5367	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Petroselinate biosynthesis"
XP_046593749.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046591043.1	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046597566.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_015515953.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046595783.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015517410.1	17	Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8951664	"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation"
XP_015516354.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046592810.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015520739.1	17	Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-445989	"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"Interleukin-1 signaling";"Downstream TCR signaling";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_046601345.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046593481.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046592330.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015510965.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046595756.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592966.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis"
XP_015524845.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015514598.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046599863.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046596018.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046592385.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_015515849.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046586801.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046598608.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046602021.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes"
XP_046591273.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046593011.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046599862.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_015518515.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015516187.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes"
XP_046587788.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046588405.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_015513268.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_015510780.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046599371.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046589454.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_015515985.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_015516943.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046598448.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046592933.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046592037.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_015522560.2	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_046588199.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046587704.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046593669.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046589610.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_015517576.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism"
XP_046596383.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_046587792.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046600271.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_015518387.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046600162.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015521777.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Neutrophil degranulation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_015510406.2	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_015524515.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046587522.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591919.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015512071.2	6	MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_015519706.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy"
XP_015509652.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_015514513.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046593837.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_015522540.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_015516792.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591363.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_015511908.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_015523777.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_015523296.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015520693.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_015519415.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_015519222.2	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_015519549.2	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046586095.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046591668.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015524035.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046594759.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593859.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_015519717.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_015515450.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046593245.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046594791.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046590766.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046596371.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_046588132.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015524592.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046600273.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046592344.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_015514637.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046598272.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_015509747.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046591258.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046586756.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_046594245.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_015523563.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_015516901.2	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_015515842.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_015512280.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_046602249.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_015520823.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046595940.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046594070.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_015509593.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046602811.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046601944.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046591939.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046587854.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_015510652.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046593851.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046598317.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_046601266.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046600709.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015518899.1	8	MetaCyc: PWY-4661;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism"
XP_015517119.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015515408.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015516856.2	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_046588918.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_015517212.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_046591545.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046594583.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_015518254.1	6	Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)"
XP_046591948.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_015522874.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_015510284.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046600624.1	6	Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"3-phosphoinositide degradation"
XP_046601830.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588300.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046592839.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046599312.1	5	KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_015509346.2	3	Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_015515024.2	7	Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046587587.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_046594366.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952	"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions"
XP_015523986.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046598209.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046593306.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046598708.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_015519282.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_046600487.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015524157.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046588569.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_015509854.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion"
XP_046595499.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_015513332.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046602232.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_015517541.2	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046591047.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046602464.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_015519852.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046592650.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046599047.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_015520112.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_015516447.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_015518429.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046593642.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_015510425.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046602431.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_046589387.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046595865.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015511454.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046597259.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_015521540.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046601014.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046593469.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571	"Ion homeostasis";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation"
XP_046598781.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046596272.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis"
XP_015519396.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_015523667.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015511408.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046591359.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046595373.1	18	Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-1221632;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-3108214;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Meiotic synapsis";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination"
XP_046602206.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046595149.1	12	MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_015517300.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Clathrin-mediated endocytosis"
XP_046586906.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046601490.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_015521993.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_046595679.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_015524756.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_015517515.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046592874.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257	"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion"
XP_046585783.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_046598370.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_015523521.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_046587703.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046591253.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_015512923.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_015521584.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046600717.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_015514834.2	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_015516029.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046594670.1	12	KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9	"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Sucrose biosynthesis II";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions"
XP_046601282.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046586596.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_015511642.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017	"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046600200.1	3	KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046585949.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_046598273.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046592150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015523812.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046589468.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046592641.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046602150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015521475.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015525114.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046586329.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_015510820.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_015512852.1	13	MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9	"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes"
XP_046595237.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046588682.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_015513324.1	11	Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-388841	"PECAM1 interactions";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"PD-1 signaling";"Costimulation by the CD28 family"
XP_015515347.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046598333.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046601528.1	6	KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527	"Galactose metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation"
XP_015520833.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_046594534.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-512988;Reactome: R-HSA-210990;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-877312	"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PECAM1 interactions";"Interferon alpha/beta signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Regulation of IFNG signaling"
XP_046602738.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046588995.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588250.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046600884.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046589492.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_015518234.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046595421.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046594220.1	5	Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221	"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway"
XP_046599258.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046595580.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_015517848.1	13	KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II"
XP_046597954.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046595344.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046588220.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits"
XP_046586701.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046586356.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046594435.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015515541.2	14	Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by REV1"
XP_046594115.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_015524488.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_015524823.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_015514614.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_046587900.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_015520179.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015523745.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_015516981.2	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046599975.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_015521478.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257	"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion"
XP_015518294.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_015515846.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046591768.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046597418.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_015514510.2	8	Reactome: R-HSA-5696395;Reactome: R-HSA-8949664;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"Processing of SMDT1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_046602503.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_015523670.2	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046590001.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046598978.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_015510898.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046596337.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_015509455.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_046594938.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_015511093.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_046591788.1	9	Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324	"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046600777.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_015524118.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046596688.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_015514346.2	6	Reactome: R-HSA-76071;KEGG: 00730+3.1.3.2;Reactome: R-HSA-6807505;Reactome: R-HSA-749476;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Thiamine metabolism";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"Phosphate acquisition";"Riboflavin metabolism"
XP_046591965.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046599632.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-196025	"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions"
XP_015514778.2	7	Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724	"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Regulation of PTEN gene transcription"
XP_046586572.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_046594724.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_015522402.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-1912408;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585;Reactome: R-HSA-69231	"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence";"Cyclin D associated events in G1"
XP_046586828.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_046588763.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790	"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer"
XP_046590764.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046589801.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_015522788.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_015511110.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046597309.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046601769.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046590046.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046600677.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046590042.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015509725.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046589141.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046588182.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015513737.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_015511534.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_015520067.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_015516119.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_015517222.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046587115.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015520050.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046599757.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015519002.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_015511791.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015511273.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-1187;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_015513267.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_046590356.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015509699.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_046589530.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_015520784.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046589818.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046597531.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_015521828.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_015511790.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046586375.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046600781.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747	"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated"
XP_046599916.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046589108.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015524562.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046589848.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046593499.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046589554.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_046599969.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015512595.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046599080.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_015514825.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation"
XP_046586285.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_015518544.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046599300.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_046589109.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046597045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_015511527.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046587064.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046597522.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046597069.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046596877.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593121.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046602335.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046595576.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_015511943.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_015514850.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046585787.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046589138.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324	"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046587698.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046599236.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046591039.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_015515448.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046594003.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046593056.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_015511135.1	22	MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7728;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-7592	"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_015517542.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046592558.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363	"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046600858.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046598763.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046597217.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_046596039.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_015517654.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_046592786.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_046593308.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-76005	"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+"
XP_046601875.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046594295.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_015509589.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_015510940.2	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_046588670.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_015509337.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_015515229.2	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_015511900.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_015519277.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_015510443.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046599462.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856	"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling"
XP_015514160.2	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046598418.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046591146.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046601427.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_015519722.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_015513758.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046597258.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046592265.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046592337.1	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_015514148.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593767.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046602023.1	12	KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis"
XP_046596934.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046595946.1	17	MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6	"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism"
XP_046586200.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046601349.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046586634.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_015509791.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046589440.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_015511796.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_015512240.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_015521158.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_015511703.2	6	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_015516987.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_015523825.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046588869.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex"
XP_046590476.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046600135.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046587783.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_015511965.1	5	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_015521015.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046592881.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_015521734.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847	"UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones"
XP_015510200.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046599354.1	13	Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-416993	"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors"
XP_046585744.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation"
XP_015519301.1	31	MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-199220	"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_046586207.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_015521593.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046594027.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238	"Neutrophil degranulation";"Starch degradation V";"Glycogen degradation II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II"
XP_046589459.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046589871.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_015517403.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046593055.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_046598597.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978	"Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production"
XP_046602338.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046598395.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_015516902.2	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_046593317.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046587721.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_015524807.2	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082	"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_046599778.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046595027.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_015509394.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046591369.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway"
XP_046595584.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046600979.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_015523104.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046595022.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_015521913.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_015516473.2	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_015519776.2	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_015511338.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015522328.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046594262.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_015523987.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_015517682.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_015517653.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_015520651.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791	"Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_015514221.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_015515167.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_015517109.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046586614.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046588197.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046587304.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046593771.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_015514703.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_015522253.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046591661.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046596347.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_015518001.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046592550.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_046596643.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"Purine metabolism"
XP_015514961.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046586517.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_015516205.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_015513116.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_015522186.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046588574.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_015512918.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_015518282.1	10	MetaCyc: PWY-5890;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-5849	"Menaquinol-10 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis"
XP_046589275.1	11	MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-6538;Reactome: R-HSA-74259;MetaCyc: PWY-6607;Reactome: R-HSA-8851680;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6999	"Guanosine nucleotides degradation II";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Guanosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation"
XP_015513118.2	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046597304.1	7	MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8	"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism"
XP_015516164.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046602300.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046591312.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046591665.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046601770.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_015520215.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_015518516.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046597405.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_015510162.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"