Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_046612684.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046626647.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046626347.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046627985.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046627736.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046608618.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_046604436.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046603952.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_046603783.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046622658.1	29	Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167200	"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046617193.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_046618728.1	7	MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610	"(aminomethyl)phosphonate degradation";"Purine metabolism";"Purine salvage";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage"
XP_046618105.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046620807.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046610491.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046607984.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046609927.1	6	KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124	"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II"
XP_046613254.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046607304.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_046610075.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_046621819.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_046616902.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046623179.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046609670.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046614252.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046612329.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_046614572.1	42	Reactome: R-HSA-171306;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-2559586;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459	"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage/Telomere Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDACs deacetylate histones";"HATs acetylate histones";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046610913.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-195253	"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"UCH proteinases";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex"
XP_046628337.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046613241.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046614614.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046622347.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046617186.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046605873.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046602853.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046629630.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612258.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046629557.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046613599.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_046610715.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046613624.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046612314.1	11	MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-5695;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6607	"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I"
XP_046611854.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046619060.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_046613022.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046602987.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046618643.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046626911.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_046622305.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046608893.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046624132.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046608694.1	31	MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-7388	"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)"
XP_046630556.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046624421.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046608065.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046629004.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046616256.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046625246.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046629902.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046608999.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046612689.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613548.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046626569.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046623395.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046626394.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046609556.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046622628.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046621848.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046630331.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046602834.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046630521.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_046612763.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Meiotic synapsis";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046609683.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046616191.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046616612.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_046611607.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_046620993.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling"
XP_046605547.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046618057.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046619384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603017.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046626620.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
XP_046620381.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046613792.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_046616274.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046605506.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_046626237.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046620947.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046615943.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046630485.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046609374.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046619240.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046623108.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046624762.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046620590.1	18	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PG"
XP_046627336.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-76042	"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046612821.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-445355	"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction"
XP_046614552.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism"
XP_046626454.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_046622790.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"Gap junction assembly";"Aggrephagy";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046623916.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046630269.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046613960.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046606380.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628145.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046627783.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046608101.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052	"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"DAP12 signaling";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis"
XP_046611355.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046619867.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046623901.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_046623193.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_046624398.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046630509.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_046614559.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046616523.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046613506.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046624010.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046611550.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046616496.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs"
XP_046630324.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046620279.1	12	KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122	"Purine metabolism";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_046614842.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046614223.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046617033.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046620931.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046603913.1	17	Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4086398	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"Downstream TCR signaling";"Ub-specific processing proteases";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Ca2+ pathway"
XP_046603464.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046630510.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_046611876.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046615056.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046608929.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046608371.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046613929.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046610493.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046628511.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046614872.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046623124.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046610955.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046606512.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046630341.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617475.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046605485.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046626416.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046621464.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046605215.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046616654.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046604849.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046613561.1	5	Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688	"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Proline catabolism"
XP_046616082.1	19	MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5392;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-7384;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538	"Methylaspartate cycle";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI"
XP_046616680.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046614355.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism"
XP_046607379.1	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046627550.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_046603372.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046618135.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism"
XP_046628861.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046619862.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046602917.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046605501.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_046609776.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046617543.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046607395.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046613165.1	10	Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484	"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_046622335.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046611154.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046630019.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046610098.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046607985.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046609308.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176407	"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046603884.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046604255.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046609111.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046621252.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046622091.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_046628006.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046621820.1	11	MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659	"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis"
XP_046613364.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_046616332.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046620750.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046617157.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_046617438.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046603468.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046617772.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046611605.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes"
XP_046602835.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046629010.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046624720.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046619813.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627855.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046619451.1	18	Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;MetaCyc: PWY-7511;Reactome: R-HSA-8953750;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5689901;Reactome: R-HSA-5693616	"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Protein ubiquitination";"Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Metalloprotease DUBs";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046604306.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046617747.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046607962.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046610150.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046627731.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046609967.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046630333.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629175.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_046614437.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046615616.1	8	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046603507.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046611422.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046605793.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_046622291.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_046613629.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046606756.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046603996.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046612322.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610688.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046614528.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_046622396.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046606256.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046629478.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046626120.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046625216.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046607398.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046616153.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046603622.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046607951.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624765.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046627137.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046627427.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046604733.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046628283.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046617103.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_046624661.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046613245.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046624400.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046618484.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_046610866.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046615455.1	9	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7902;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle"
XP_046621533.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046603621.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046627234.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_046608339.1	6	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046623452.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046620568.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_046616967.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_046609842.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"One carbon pool by folate"
XP_046629739.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046623410.1	5	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046619104.1	4	MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046615405.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046618172.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046606629.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046629215.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_046606272.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_046609797.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046603702.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046628286.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046622507.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628108.1	17	Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;KEGG: 04660+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167158	"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"T cell receptor signaling pathway";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex"
XP_046603500.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046624393.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046621616.1	9	Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046609056.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046614104.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046621057.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046611475.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046611903.1	29	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-3371453;Reactome: R-HSA-5693579;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6803207;Reactome: R-HSA-5693616;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69541;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of HSF1-mediated heat shock response";"Homologous DNA Pairing and Strand Exchange";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Thermogenesis";"Regulation of TP53 Degradation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Stabilization of p53";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway"
XP_046607830.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_046610600.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_046621275.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_046623708.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046625627.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_046613845.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046624077.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046625215.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046616217.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046615038.1	7	KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-5265	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)"
XP_046625109.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046626848.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046619443.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_046626864.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046616822.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046624109.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046609302.1	30	Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-1170546;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323	"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Prolactin receptor signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Circadian Clock";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling"
XP_046607254.1	16	Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174184	"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046618986.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046622461.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046624520.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046605871.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046622766.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046612366.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_046606375.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046608303.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046610433.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046609215.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046604346.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046610984.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046611036.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_046616495.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230	"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_046629829.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046622426.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046620656.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046605429.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046606726.1	4	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_046622176.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046630474.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046628527.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046624337.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174154	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin"
XP_046608652.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046624063.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046605443.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046613898.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation"
XP_046615483.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046614312.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046623219.1	11	MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913	"L-glutamine biosynthesis III";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)"
XP_046608713.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_046605681.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046616074.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA"
XP_046611125.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046630440.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_046608144.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046628095.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046613486.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046609513.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046619337.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046621970.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046608926.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_046609244.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046616903.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046609542.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA"
XP_046629365.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617300.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_046603733.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046617770.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046624242.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_046628818.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046619390.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046604495.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046618998.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046620799.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046611066.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046627121.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046603822.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046616985.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046624882.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046615400.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046604196.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-5497;Reactome: R-HSA-196757	"Folate transformations I";"Glycine betaine degradation I";"Folate polyglutamylation";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines"
XP_046630124.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046617668.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_046629292.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046615655.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380320	"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Aggrephagy";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes"
XP_046607317.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046611908.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046621812.1	11	MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation"
XP_046612592.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046622371.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046627257.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046609989.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628422.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046611996.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046614634.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046609630.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046629644.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046627258.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046624800.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046610763.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046609350.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_046616108.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046624014.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046603485.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046617462.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_046609764.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046613493.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046624372.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046624335.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046621671.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046608397.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046616314.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046615890.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046609800.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046628462.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046615284.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046605445.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046607626.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046622835.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046604803.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046624945.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046615923.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046613670.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046611338.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046604301.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046606415.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046612006.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_046627982.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046624370.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_046603876.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046625344.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046610593.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Macroautophagy";"Aggrephagy"
XP_046620812.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046613230.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629787.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046626238.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046628492.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_046606758.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751	"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated"
XP_046619120.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046624087.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs"
XP_046628556.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619005.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046612073.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_046607089.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046605348.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_046609579.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046630044.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_046625360.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046612893.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046613407.1	4	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis"
XP_046617380.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046615971.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046626849.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046627425.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046630272.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_046626791.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046609459.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046605465.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_046610755.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046607371.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_046610811.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046617733.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046622701.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_046609201.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_046626346.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046613525.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046621280.1	11	Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_046630345.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602983.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_046603140.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_046617636.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046614283.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571	"Ion transport by P-type ATPases";"Ion homeostasis";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation"
XP_046606731.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins"
XP_046623090.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046616258.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046606523.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046624104.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046604478.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046626132.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046620740.1	4	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17	"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis"
XP_046611175.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046619634.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_046626696.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046615338.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046605375.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_046610258.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins"
XP_046611421.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046603044.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046624169.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046614795.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_046609472.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046611910.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046625341.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046608294.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612561.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046628265.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_046619845.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046611886.1	8	MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_046624889.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046614810.1	11	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity"
XP_046628572.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046623386.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046625908.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046606822.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046627873.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046623245.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_046604151.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046605850.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones"
XP_046614335.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-200425	"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism"
XP_046611262.1	19	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197	"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_046616472.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046614612.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046604577.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046618739.1	7	Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;MetaCyc: PWY-7807	"Purine salvage";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II";"Adenine salvage";"Neutrophil degranulation";"Glyphosate degradation III"
XP_046604091.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046628452.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_046614950.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_046622042.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_046630216.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_046608593.1	42	Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-2559586;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-110331;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-427413;Reactome: R-HSA-73728	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"DNA methylation";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged purine";"RMTs methylate histone arginines";"HDACs deacetylate histones";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"HCMV Early Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening"
XP_046623086.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_046603777.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046627633.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_046618825.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046603081.1	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_046603467.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046627111.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046604303.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046618723.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046606956.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046606996.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_046614448.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046606736.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046629447.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046626122.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046624386.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046629121.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046615613.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)"
XP_046609577.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046622565.1	9	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046621210.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins"
XP_046618870.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046615634.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046613966.1	33	KEGG: 00071+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5078;MetaCyc: PWY-6333;MetaCyc: PWY-6313;Reactome: R-HSA-71384;MetaCyc: PWY-5057;KEGG: 00626+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00680+1.1.1.284;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5082;MetaCyc: PWY-1801;MetaCyc: PWY-5480;MetaCyc: PWY-7396;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-6871;KEGG: 00260+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5751;MetaCyc: PWY-6342;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00980+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-7798;MetaCyc: PWY-5486;MetaCyc: PWY-5076	"Fatty acid degradation";"(S)-propane-1,2-diol degradation";"L-isoleucine degradation II";"Acetaldehyde biosynthesis I";"Serotonin degradation";"Ethanol oxidation";"L-valine degradation II";"Naphthalene degradation";"L-tryptophan degradation V (side chain pathway)";"Methane metabolism";"Drug metabolism - cytochrome P450";"Chitin degradation to ethanol";"L-methionine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol I";"Butanol and isobutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Salidroside biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"alpha-Linolenic acid metabolism";"Retinol metabolism";"Pyruvate fermentation to ethanol III";"Phenylethanol biosynthesis";"Noradrenaline and adrenaline degradation";"Tyrosine metabolism";"L-phenylalanine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to isobutanol (engineered)";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol II";"L-leucine degradation III"
XP_046610810.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_046607983.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046629830.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046621768.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046616115.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046622733.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
XP_046612124.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046613534.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046616745.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_046604054.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624453.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046623331.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046626107.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046620007.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046604918.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046607222.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170	"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_046604500.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046614053.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046604723.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046625703.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_046619998.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046623727.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046622652.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046619217.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_046628071.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_046624177.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046628680.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046607361.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046625975.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046607320.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046626803.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046629873.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046627610.1	30	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-2564830;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167172	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"mRNA Capping";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cytosolic iron-sulfur cluster assembly";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome"
XP_046612829.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_046617151.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_046618370.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612978.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion"
XP_046613313.1	6	Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_046622632.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_046623816.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046628702.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046604206.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046616340.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046604877.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046625569.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046604487.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism"
XP_046614895.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_046623444.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046605090.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046621300.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046618936.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046630346.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629449.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_046607391.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046614915.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046621675.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046626886.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046613632.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046615581.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046620012.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606894.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression"
XP_046615277.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619	"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis"
XP_046612309.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046625553.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_046618487.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046605780.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046616529.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605803.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_046605523.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046617440.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_046626542.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_046606361.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_046608063.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046624081.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
XP_046603382.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046618734.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046625525.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046610376.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046621645.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046629906.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046605486.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046604840.1	8	KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901	"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_046616933.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628938.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046610128.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046613673.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628899.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I"
XP_046622866.1	6	MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18	"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_046603993.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046604488.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046604095.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046611431.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_046613609.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046625029.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046613788.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046611387.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_046617918.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919	"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils"
XP_046603502.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046614293.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_046604166.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628885.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046629278.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046612981.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046615116.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046603613.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046625579.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627253.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046606131.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046623586.1	8	KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
XP_046618083.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046617643.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046610018.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV"
XP_046624349.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046604447.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046612074.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046614520.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046629520.1	4	Reactome: R-HSA-156582;KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;KEGG: 00633+2.3.1.5	"Acetylation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Nitrotoluene degradation"
XP_046612051.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046604571.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy"
XP_046603678.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046615831.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_046605883.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046611872.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046611143.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_046615568.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046603488.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046629332.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_046604758.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_046603501.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046611970.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046627962.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046609677.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712	"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling"
XP_046611240.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046626761.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046622070.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046628104.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046612663.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046606631.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046622445.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046603907.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046618000.1	17	MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-200425;MetaCyc: PWY-5743	"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Glyoxylate assimilation";"Carnitine metabolism";"3-hydroxypropanoate cycle"
XP_046628288.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046629828.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046622421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046608287.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046628121.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046613866.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046609692.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046612316.1	11	Reactome: R-HSA-8851680;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6538;Reactome: R-HSA-74259	"Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism"
XP_046606708.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046614056.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046627341.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603994.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046629368.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602992.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046619633.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_046623859.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046604363.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046628502.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625768.1	5	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_046624383.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046626926.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046621339.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046612096.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046623214.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_046624699.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046622234.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046612586.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_046610153.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046614646.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_046618733.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046616905.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046610266.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605316.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046619079.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_046625239.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046624112.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046611900.1	29	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803207;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-69541;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Human papillomavirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Thermogenesis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Stabilization of p53";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination"
XP_046627532.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613346.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046626716.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_046626242.1	4	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_046628002.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046612892.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport"
XP_046614633.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046611359.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046621461.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046628890.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046624621.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046612696.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046623321.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046621383.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046627195.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046622987.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046630201.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046612347.1	16	Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
XP_046604551.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046603729.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046617256.1	7	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4	"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_046604779.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046624099.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046604090.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046604646.1	12	Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046622275.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046629065.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_046616646.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046605840.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_046616556.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046614372.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571	"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation"
XP_046616071.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699	"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels"
XP_046609243.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046625866.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_046622080.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046618809.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73863	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination"
XP_046611324.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_046621661.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046609702.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046613532.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046617802.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046629337.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046612651.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1	"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism"
XP_046623598.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046621635.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046613479.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046615921.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046616843.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046616429.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046621945.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046622420.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation"
XP_046615989.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046624895.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046626545.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046623976.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046607262.1	34	Reactome: R-HSA-4085377;Reactome: R-HSA-9639288;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-180910	"SUMOylation of SUMOylation proteins";"Amino acids regulate mTORC1";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs"
XP_046627734.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046629030.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046627440.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046622392.1	11	Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"p38MAPK events";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_046608964.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_046606390.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046619170.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144	"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling"
XP_046604079.1	7	MetaCyc: PWY-6906;Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31	"Chitin derivatives degradation";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway"
XP_046606986.1	10	KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis"
XP_046627438.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046625995.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691	"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I"
XP_046603556.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046620930.1	33	Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046624850.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046610374.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046603982.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046628267.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_046626686.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046611163.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046603250.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;MetaCyc: PWY-5691	"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Amyloid fiber formation";"Urate conversion to allantoin I"
XP_046611168.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046628372.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_046609373.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046611967.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046621823.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_046623336.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046613501.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046626801.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046629444.1	6	MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_046617162.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046622774.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046604954.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_046607471.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046618556.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_046608509.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046603235.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608302.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046615695.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046619836.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046613448.1	11	Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-391160	"Platelet sensitization by LDL";"Regulation of IFNG signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Interferon alpha/beta signaling";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"PECAM1 interactions";"Signal regulatory protein family interactions"
XP_046622629.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046605462.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046619534.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046612969.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_046627519.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_046624897.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046606360.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046603986.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046622504.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046621542.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_046612903.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625060.1	11	KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis"
XP_046611258.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046616776.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046603198.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046605635.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046626397.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046615885.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046618180.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046624592.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046629034.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_046609055.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046604440.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_046624617.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046611968.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046615207.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_046621810.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046626275.1	5	KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism"
XP_046622393.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007	"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events"
XP_046609471.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046606273.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_046628332.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_046612661.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427359	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression"
XP_046622548.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_046617137.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046607700.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046615168.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416476	"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"G-protein activation";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events"
XP_046612548.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046626721.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_046614358.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046607403.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046629042.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046627034.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614015.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046624153.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_046616476.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046622854.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046615008.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046624900.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046621894.1	24	Reactome: R-HSA-4420097;Reactome: R-HSA-180024;Reactome: R-HSA-111931;Reactome: R-HSA-422356;Reactome: R-HSA-432040;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-442720;Reactome: R-HSA-8963896;Reactome: R-HSA-381676;Reactome: R-HSA-9634600;Reactome: R-HSA-5610785;Reactome: R-HSA-9010642;Reactome: R-HSA-163358;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163615;Reactome: R-HSA-8853659;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5621575;Reactome: R-HSA-163560;Reactome: R-HSA-392517	"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"PKA-mediated phosphorylation of CREB";"Regulation of insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"HDL assembly";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"GLI3 is processed to GLI3R by the proteasome";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of key metabolic factors";"mTOR signaling pathway";"PKA activation";"RET signaling";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CD209 (DC-SIGN) signaling";"Triglyceride catabolism";"Rap1 signalling"
XP_046628416.1	57	Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276	"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046628464.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046602968.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046622271.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046611001.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046628079.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046618005.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629754.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046619812.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612434.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046616443.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046609580.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046619057.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046604245.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046612968.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation"
XP_046620781.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046618800.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075	"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_046628008.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046603624.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046619857.1	20	Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Polymerase switching";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_046622488.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046629564.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046609393.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046608711.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex"
XP_046612881.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling"
XP_046630373.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046626524.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046615132.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046624310.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_046627562.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046607751.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625085.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade"
XP_046627621.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Neutrophil degranulation"
XP_046622626.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046603887.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046626997.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046614366.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622363.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046615160.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046617805.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690	"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"HCMV Early Events"
XP_046609706.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046623085.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046616485.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_046621049.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046629772.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046628507.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046619992.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046605639.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046624733.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046615281.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046604940.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-5696397;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_046617241.1	12	KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417	"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046603557.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046618093.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046606519.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046610604.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046611375.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046630442.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046620621.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046618730.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046605852.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_046628974.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046624302.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046610375.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046609153.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-5651801	"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair"
XP_046623563.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046612458.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258	"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL"
XP_046612393.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_046616547.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_046617428.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046617511.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046603527.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046613282.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184	"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046615324.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227	"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA"
XP_046620497.1	8	MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193	"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_046609045.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046630438.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046615579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046622108.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603492.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046603751.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_046609869.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046603458.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046629277.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046627776.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_046619549.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046605331.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046603807.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-168315;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Inhibition of Host mRNA Processing and RNA Silencing";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_046611780.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046606002.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618932.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148	"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046606949.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046621762.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_046609422.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_046626398.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046624061.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046616218.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046611058.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA"
XP_046622923.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046628541.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046605314.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046626976.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046608992.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046621353.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046620011.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606312.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046625470.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-2132295	"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation"
XP_046615276.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046616155.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046619562.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046610990.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046606983.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6	"Neutrophil degranulation";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_046621756.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046624008.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-8876198	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"RAB GEFs exchange GTP for GDP on RABs"
XP_046610569.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_046624103.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046623247.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046611992.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046623842.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585	"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence"
XP_046609806.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I"
XP_046605329.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612553.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046616473.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046623583.1	8	KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1	"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis"
XP_046616184.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046628700.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046604557.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046626934.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046612408.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_046614257.1	3	Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857	"Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis"
XP_046627732.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046615314.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046613487.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046616600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046623268.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046620716.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7736	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis"
XP_046615545.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-977225	"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Amyloid fiber formation"
XP_046622123.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046609607.1	9	MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)"
XP_046616744.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046604327.1	3	MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3	"Urate conversion to allantoin I";"Purine metabolism";"Caffeine metabolism"
XP_046625335.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_046606998.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046620680.1	6	Reactome: R-HSA-1268020;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980	"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis"
XP_046625969.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046604516.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046624484.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_046621899.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046623352.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_046624096.1	16	Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3214847	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HATs acetylate histones"
XP_046617459.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624903.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046626402.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046605228.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616774.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_046607431.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046622646.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046611109.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603701.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046616246.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046618125.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046606416.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046613027.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046613314.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+"
XP_046603493.1	5	KEGG: 00790+3.4.19.9;KEGG: 00513+2.4.1.142;MetaCyc: PWY-2161B;KEGG: 00510+2.4.1.142;Reactome: R-HSA-6798695	"Folate biosynthesis";"Various types of N-glycan biosynthesis";"Glutamate removal from folates";"N-Glycan biosynthesis";"Neutrophil degranulation"
XP_046624173.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046608508.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046611514.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_046606378.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046610920.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046611063.1	7	Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046614824.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046622986.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046612205.1	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_046614570.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046616866.1	5	KEGG: 00270+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010	"Cysteine and methionine metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_046623593.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046621127.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046620865.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046617700.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046620794.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"Macroautophagy"
XP_046612714.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046612018.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_046613310.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046619955.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046628737.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046616799.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046614246.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_046626869.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046611009.1	7	KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_046618026.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_046628226.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8852276	"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Gap junction assembly";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_046618352.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046614133.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046623262.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046604434.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046606330.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046615780.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046622797.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735	"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis"
XP_046623447.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_046625685.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858	"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity"
XP_046621548.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046617176.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER"
XP_046630446.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_046613830.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_046619584.1	9	Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5678895;Reactome: R-HSA-5627083;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710	"Ub-specific processing proteases";"Aggrephagy";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"RHO GTPases regulate CFTR trafficking";"Chaperone Mediated Autophagy";"Late endosomal microautophagy"
XP_046612599.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046628911.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046614323.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_046617356.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046616463.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-983231	"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"HDMs demethylate histones";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production"
XP_046608670.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046611377.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046606453.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_046604006.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046622938.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046609592.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_046611852.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046612883.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025	"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation"
XP_046619355.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046623597.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046618357.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046615962.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046613638.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046610676.1	13	MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism"
XP_046626712.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046628461.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046625839.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046612049.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046625104.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046603267.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046627066.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_046609591.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_046607033.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046613424.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046617557.1	14	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-9013700	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_046625902.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046615733.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046616013.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_046616064.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_046626865.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046629748.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046615614.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)"
XP_046623123.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046607750.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046615229.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046620941.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046609818.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046612791.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_046614731.1	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_046625686.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046615463.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046609371.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046620791.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"Macroautophagy";"HSF1-dependent transactivation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_046614801.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046605892.1	17	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_046624793.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046618107.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046627579.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046627313.1	13	MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722	"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_046622857.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046630344.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046619054.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046618043.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046613559.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046617818.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046607652.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_046621874.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046603443.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618961.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046628501.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612589.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627972.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046606467.1	7	Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046603083.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_046623269.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046615035.1	13	KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690	"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)"
XP_046614168.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046611756.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046622375.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046629396.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606638.1	8	Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046617072.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046626817.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046615042.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046625472.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046616265.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-373753	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Nephrin family interactions"
XP_046613125.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046604852.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046626674.1	9	Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6142;MetaCyc: PWY-6146	"Gluconeogenesis";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Biotin transport and metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_046604743.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046615708.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046608512.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
XP_046628454.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy"
XP_046625993.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046618982.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046604828.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046604766.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046622300.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046620017.1	20	MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7288	"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_046606068.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046611734.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046618024.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046611817.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046621644.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046625889.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046607080.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046626568.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046607236.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046614324.1	3	Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-383280	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046607075.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046617741.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-3214847	"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones"
XP_046622917.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670	"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis"
XP_046612403.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046623704.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046629141.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046628898.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_046615047.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046609931.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046618025.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_046614179.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046609588.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription"
XP_046614264.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046617393.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046620015.1	20	MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136	"Jasmonic acid biosynthesis";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046622035.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046622683.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046629796.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046625639.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046628373.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046628916.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046603403.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046616251.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046615080.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616651.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046625359.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046613367.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046622464.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046617030.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046613219.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046611711.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046619811.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046620345.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046605202.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046606259.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046625265.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_046607725.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046615523.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_046622785.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_046609676.1	6	Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731	"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_046607366.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046626770.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046611028.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_046611156.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046613660.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046628856.1	14	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046617040.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046623982.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046626804.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046615972.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046612402.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046607035.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046609656.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046609212.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046617439.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046615694.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046611259.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046622112.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046607793.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046611685.1	12	MetaCyc: PWY-7385;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13	"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
XP_046624086.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN"
XP_046626697.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046623421.1	4	KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755583	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_046612335.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_046628695.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046613123.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046628065.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046627189.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046627143.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046613557.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046618136.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_046606490.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046611257.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046624255.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046617899.1	5	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_046626573.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046619205.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046604457.1	15	Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046625701.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_046613650.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046612826.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_046620856.1	10	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046620280.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046626619.1	3	Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893	"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase"
XP_046604920.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046607330.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046614030.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629939.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046628857.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_046610102.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046620078.1	17	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Meiotic synapsis";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Fanconi Anemia Pathway";"Human cytomegalovirus infection"
XP_046607332.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046606743.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046625083.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade"
XP_046625983.1	30	Reactome: R-HSA-1170546;Reactome: R-HSA-5610783;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-983168	"Prolactin receptor signaling";"Degradation of GLI2 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046611530.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046627343.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046608259.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046620372.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046616615.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046615456.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046622922.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046602924.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_046606067.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606933.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-168325;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046612165.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046624852.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046621787.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046611553.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046606239.1	13	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection"
XP_046608037.1	7	Reactome: R-HSA-2160456;MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158	"Phenylketonuria";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_046627243.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_046630519.1	42	MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7656;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6944;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7779;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00640+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7007;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-6945;MetaCyc: PWY-6946	"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Tryptophan metabolism";"Fatty acid elongation";"Toluene degradation";"Fatty acid salvage";"Androstenedione degradation";"beta-Alanine metabolism";"Pyruvate fermentation to butanol I";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"Geraniol degradation";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Propanoate metabolism";"Limonene and pinene degradation";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"Benzoate degradation";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"
XP_046629733.1	7	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Deadenylation of mRNA";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046629494.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046606694.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046621307.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_046613597.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606248.1	8	Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_046606420.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607393.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046628399.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749	"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated"
XP_046623271.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046618308.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046624576.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_046608216.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046620075.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046612334.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046619589.1	9	Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-5627083;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710	"Ub-specific processing proteases";"Aggrephagy";"RHO GTPases regulate CFTR trafficking";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Chaperone Mediated Autophagy";"Late endosomal microautophagy"
XP_046630380.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046612202.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_046619325.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046612047.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046611388.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046607819.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046611763.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046621094.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046610985.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_046623592.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046608409.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046625277.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046617509.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046620719.1	13	MetaCyc: PWY-5123;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-6859	"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"All-trans-farnesol biosynthesis"
XP_046625301.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046603300.1	14	Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8055;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4	"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_046614183.1	5	KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_046611710.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046622660.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_046604360.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046624415.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046612222.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046607359.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046604092.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046604112.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000	"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF activation"
XP_046624406.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"mTOR signaling pathway"
XP_046629161.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046610197.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046606804.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461	"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation"
XP_046613585.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_046605997.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_046628585.1	12	KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857	"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis"
XP_046615020.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046623729.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis"
XP_046621244.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046628576.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046629723.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046605503.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_046609241.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046615067.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046622793.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-735	"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis"
XP_046615076.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046604386.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046625555.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_046618600.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_046620022.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046621769.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation"
XP_046604721.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046604831.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046628525.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046617024.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046605502.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_046603357.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046623122.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046620276.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046620713.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618820.1	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_046623931.1	9	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule"
XP_046609252.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046629722.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046624161.1	5	Reactome: R-HSA-193048;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046608962.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046603113.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607031.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046613024.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046620765.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046618827.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046603405.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046628738.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046608376.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046604103.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046622625.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046629751.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046613158.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"HS-GAG biosynthesis"
XP_046602908.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163	"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_046614089.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046615705.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046615273.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046626878.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046614166.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046603638.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046618880.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690	"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"HCMV Early Events"
XP_046611911.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046624843.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046624080.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046617544.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046615653.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-6527;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817	"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046625901.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046606374.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629647.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046618955.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046619357.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046621640.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046615650.1	12	KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9	"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Glycerolipid metabolism"
XP_046615580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628513.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046616908.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046607231.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_046613142.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046616180.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046604208.1	16	Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Gap junction degradation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Formation of annular gap junctions";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_046604239.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046620138.1	8	MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6611	"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage V"
XP_046629176.1	6	MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151	"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046611152.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046625903.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046616988.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046612788.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_046618369.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046617452.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_046609343.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046623668.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046621763.1	4	KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I"
XP_046606691.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046626209.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046614879.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046616565.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046612565.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046604810.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046612896.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046629366.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629059.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046626776.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_046627555.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046622463.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046624176.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046622383.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046616601.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046615510.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046629804.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046619704.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046620605.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046622630.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046630233.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046613507.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046612847.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046612876.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_046628329.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480	"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"LDL clearance";"VLDL assembly";"Platelet sensitization by LDL";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Scavenging by Class A Receptors"
XP_046622410.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046616803.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_046618482.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_046617871.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046625916.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333	"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046604597.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes"
XP_046603525.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628636.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046607139.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046619216.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046609775.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046615217.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046624752.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046622506.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046611035.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_046607329.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046603073.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685	"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species"
XP_046611517.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses"
XP_046624195.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046622419.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation"
XP_046619490.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622320.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609290.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046603432.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046603383.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046614553.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618954.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046622269.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046624950.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046613651.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046621364.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046624396.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046615487.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046621323.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046613608.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046630524.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6783310	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway"
XP_046619863.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046609381.1	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
XP_046620009.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046623223.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_046626134.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046605537.1	32	Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167160	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_046617758.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-166208	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling"
XP_046622274.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_046622416.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408	"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation"
XP_046627309.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-6703	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis"
XP_046614261.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046620588.1	18	KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE"
XP_046627228.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism"
XP_046618912.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046603781.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046616672.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046619366.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630120.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046627954.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046613456.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046617712.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046622982.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046611904.1	29	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-69541;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-5693568;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-5693616;Reactome: R-HSA-6803207;Reactome: R-HSA-5685942;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Stabilization of p53";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Thermogenesis";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Homologous Recombination (HRR)";"Human papillomavirus infection";"Homologous DNA Pairing and Strand Exchange";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046625781.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_046623701.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613497.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046617165.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046614034.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046623495.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046616926.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046607003.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046612399.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046613337.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046628755.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046611357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046612405.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046603908.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_046606499.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046617218.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046628607.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622105.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628908.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_046606988.1	10	MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis"
XP_046625068.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide"
XP_046622368.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046610555.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;MetaCyc: PWY-7511	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination"
XP_046606682.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628185.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178	"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans"
XP_046620718.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6383	"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_046610353.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046607401.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046617411.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_046625656.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_046609734.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046606217.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046616189.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_046620016.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241	"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import"
XP_046614311.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046621400.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046617217.1	3	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis"
XP_046629768.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_046605444.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046625692.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046605234.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046604667.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046603056.1	7	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-203641;Reactome: R-HSA-8856828;Reactome: R-HSA-373753	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"NOSTRIN mediated eNOS trafficking";"Clathrin-mediated endocytosis";"Nephrin family interactions"
XP_046621639.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046618133.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046622100.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-380972	"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046606071.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624033.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism"
XP_046617155.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046611374.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046604264.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046626980.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046626881.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046617635.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046615287.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725	"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046606832.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046609585.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046620199.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046608585.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046608630.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046615926.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046620361.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046613550.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046622836.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046606545.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046626351.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046626105.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046604907.1	9	KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5	"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_046614598.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627119.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046628711.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_046618003.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722	"3-hydroxypropanoate cycle";"Carnitine metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Candicidin biosynthesis"
XP_046621694.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046612919.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046610867.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_046612666.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046607124.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046629555.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603651.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046613669.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046612350.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_046607036.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046617644.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046619496.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046619869.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046629154.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046620340.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046603988.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_046603623.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046605037.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes"
XP_046626384.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_046619001.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046629819.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046622584.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046615878.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046628391.1	3	Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_046624888.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046607649.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046607272.1	34	Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_046629248.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046613876.1	5	MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20	"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate"
XP_046623985.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046608693.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway"
XP_046627612.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_046625240.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046606759.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046607585.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation"
XP_046612902.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399	"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy"
XP_046618892.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046605274.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625988.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
XP_046608030.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603555.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046615485.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046621673.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046613603.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046625518.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_046607158.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046604222.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046611253.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046615356.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046628558.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628583.1	12	MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1	"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Propanoate metabolism";"Pyruvate metabolism"
XP_046609819.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046609671.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046625837.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_046603782.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046606665.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046629979.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046607986.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046627230.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046614446.1	42	Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-171306;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222	"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"HCMV Late Events";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"HDACs deacetylate histones";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"RMTs methylate histone arginines";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Packaging Of Telomere Ends";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis"
XP_046615668.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046616254.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046622414.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation"
XP_046623361.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046610673.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046614346.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046622440.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_046624933.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046623585.1	8	KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_046619569.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046621334.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046619881.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046622441.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_046616408.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046612963.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046624156.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046611479.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922	"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_046608837.1	31	MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746	"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis"
XP_046618599.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046612187.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046609411.1	31	MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-6113;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-7858;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5973	"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis"
XP_046623006.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_046620137.1	8	MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4	"Adenine and adenosine salvage V";"Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine metabolism"
XP_046611527.1	4	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation"
XP_046611704.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046624475.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_046628532.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046617478.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046623989.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624634.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046603414.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_046613317.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+"
XP_046618031.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046604807.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_046625195.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046606895.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression"
XP_046622704.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046622457.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_046611978.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046622411.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046616259.1	18	Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_046621872.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046627779.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046628900.1	8	MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_046612694.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_046629645.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046614201.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628714.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_046614434.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046608514.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046606542.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046605795.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046611214.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046607755.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046629499.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046608947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619169.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211976	"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Endogenous sterols"
XP_046614345.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046626704.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-164843	"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation"
XP_046611108.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617555.1	14	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_046606331.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046611481.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_046610188.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625234.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046608583.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046626130.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046628904.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046614740.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046615074.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046626577.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046608701.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_046603268.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046628421.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046613482.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046626546.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_046625174.1	3	Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_046610476.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_046627120.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612839.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046613667.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046614368.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046628183.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046627149.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046604256.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046625213.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046604140.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046618568.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624967.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation"
XP_046615929.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046628534.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046609594.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046616249.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046605038.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_046626031.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Triglyceride catabolism"
XP_046616909.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_046609159.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex"
XP_046626823.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046625567.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046616907.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046613642.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046625381.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046613606.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_046626852.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_046625221.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046621764.1	4	MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72	"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis"
XP_046622413.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-1912408	"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation"
XP_046625285.1	6	KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)"
XP_046614087.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046604548.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046626323.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_046613518.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046607377.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Signaling by Hippo";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046630471.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_046630280.1	42	MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5789;MetaCyc: PWY-1361;MetaCyc: PWY-7007;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5109;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7779;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6583	"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"Butanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoyl-coa degradation I (aerobic)";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"Propanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Caprolactam degradation";"Valine, leucine and isoleucine degradation";"Benzoate degradation";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"Geraniol degradation";"Fatty acid degradation";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Tryptophan metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Fatty acid elongation";"Fatty acid salvage";"Toluene degradation";"Androstenedione degradation";"beta-Alanine metabolism";"Pyruvate fermentation to butanol I"
XP_046606414.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046623116.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046619099.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607283.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_046609340.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046604319.1	6	Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892245;Reactome: R-HSA-3769402	"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Deactivation of the beta-catenin transactivating complex"
XP_046622351.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046621578.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046607632.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046618395.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-422356	"Role of phospholipids in phagocytosis";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Regulation of insulin secretion"
XP_046618483.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_046628625.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046618902.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046604573.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046620252.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628831.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046610383.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046611343.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_046614098.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_046614367.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046611930.1	6	MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_046614263.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046608634.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531	"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus"
XP_046621423.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046623665.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_046608651.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046619253.1	13	MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_046617346.1	10	KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70171	"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis"
XP_046612546.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046608682.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
XP_046617873.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046610105.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046603181.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_046610495.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046626917.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046621861.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046629755.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046603649.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046604100.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046613147.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046623806.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046606003.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046609509.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046625953.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046612973.1	7	Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4	"Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Geraniol degradation"
XP_046605558.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046612431.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046603883.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046619279.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins"
XP_046607017.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046625707.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046625413.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505	"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_046611208.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046605794.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622136.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046614914.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046612564.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046614518.1	4	KEGG: 00052+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9	"Galactose metabolism";"Gluconeogenesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis"
XP_046607412.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046622075.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046606843.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001	"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade"
XP_046624194.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046615830.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_046628098.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046616050.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046604202.1	9	MetaCyc: PWY-7883;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52	"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_046604358.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046624404.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046622456.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_046616107.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046617646.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046614334.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046623277.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046626774.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_046605500.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_046619162.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201	"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis"
XP_046616670.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046605636.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046624828.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046627803.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046621243.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046619710.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046605881.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046612822.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants"
XP_046613909.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046621006.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_046609880.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046615970.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046628567.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046613277.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_046625164.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613126.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046621345.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046613061.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_046622621.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046622855.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046627426.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_046611389.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_046614661.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046608666.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046618298.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046628284.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046630369.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046612401.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046615021.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046608928.1	10	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046619392.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_046607824.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_046629538.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_046612593.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046626110.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046607438.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046616106.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_046626317.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_046623703.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046604152.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615963.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046620703.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046613851.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046616277.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046621406.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046625838.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046616797.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_046621099.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046616874.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_046604471.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046626302.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046629394.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046615918.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_046619994.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046629614.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046610912.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-1368108	"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046615124.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_046619184.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046624380.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046610924.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046619837.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046617254.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7039	"Synthesis of PG";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule"
XP_046619127.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_046606821.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046612337.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046628972.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_046617009.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046619590.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-8856828;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829	"Aggrephagy";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"Clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Late endosomal microautophagy";"Chaperone Mediated Autophagy"
XP_046605797.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606947.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046628743.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER"
XP_046615666.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046619936.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046604467.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046623186.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046605548.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046609809.1	5	MetaCyc: PWY-7279;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-6692	"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation"
XP_046623519.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046621143.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046620702.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046611777.1	5	KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_046623493.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_046613649.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046625268.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_046616080.1	19	MetaCyc: PWY-5392;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-75105;MetaCyc: PWY-5913	"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)"
XP_046617213.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_046621538.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046603626.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046628647.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046623651.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046613258.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046618181.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046627335.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075	"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_046608520.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046619809.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046617735.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046613560.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046603806.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046605630.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046610246.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046627933.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6811555	"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation"
XP_046626277.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_046614159.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046603645.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046617642.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046609703.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046615270.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046625030.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046629440.1	6	KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia"
XP_046609060.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_046608515.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046626915.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046606127.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783	"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome"
XP_046607825.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-975634	"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport"
XP_046627518.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046603934.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_046614822.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046620008.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046610664.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046610283.1	3	KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_046606208.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046627035.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046620196.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046627558.1	15	KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003	"Purine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol"
XP_046617335.1	26	Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-1362277;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-4615885;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6804114;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-110312;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-8866654;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Transcription of E2F targets under negative control by DREAM complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA replication proteins";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"Translesion synthesis by REV1";"G1/S-Specific Transcription";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046618953.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046611966.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046609831.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046628428.1	10	Reactome: R-HSA-5609977;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_046603676.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046611548.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046628134.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_046629901.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_046612339.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_046614253.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046602995.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046613051.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046613652.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046619000.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046608372.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046606313.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046612594.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046605634.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046614231.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837	"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases"
XP_046621328.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_046615960.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046621331.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046630490.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046621789.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046605203.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046616996.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_046616154.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046617117.1	6	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046628706.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_046628281.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695	"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Purine metabolism";"Inosine 5'-phosphate degradation"
XP_046621532.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046614357.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_046626481.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046624930.1	1	Reactome: R-HSA-156581	"Methylation"
XP_046607731.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046619039.1	10	KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6536;MetaCyc: PWY-6537;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-5022	"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"beta-Alanine metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"Degradation of GABA";"Propanoate metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation V"
XP_046625397.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046627635.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_046604574.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046608689.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7664;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558	"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_046628705.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_046620957.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046626071.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046626899.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046622006.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes"
XP_046605204.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046613636.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046628739.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046621508.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046619134.1	16	MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5749;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.4;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism"
XP_046619687.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618929.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046606940.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859	"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly"
XP_046624346.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046625891.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046608186.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046605655.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046614860.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046620297.1	4	MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_046615913.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046613516.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046628793.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_046619609.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_046622988.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046622344.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046608158.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046613216.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046617392.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046604325.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046603985.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046626240.1	4	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_046618719.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;Reactome: R-HSA-74217;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610	"Purine metabolism";"(aminomethyl)phosphonate degradation";"Purine salvage";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage"
XP_046624454.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046618865.1	10	KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"RSK activation";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human papillomavirus infection";"Recycling pathway of L1";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046612562.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622177.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046609753.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046609494.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046613483.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046604739.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046621483.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207	"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_046609857.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046628926.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_046606809.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046621257.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046624185.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046605532.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046615283.1	14	MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_046609116.1	4	KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50	"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_046615311.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046605110.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046628374.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046612725.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046627658.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046613622.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046607965.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046605220.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046624949.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_046625007.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046605330.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046606417.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046612388.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046603504.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_046608669.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046622756.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-7727	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_046623522.1	19	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-3214858;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"RMTs methylate histone arginines";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Protein methylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_046606874.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-5466	"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis"
XP_046614199.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_046628498.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046607123.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046615282.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_046610083.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
XP_046617239.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_046618790.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167200	"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046612094.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046616790.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046621549.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046606667.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046614561.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_046602919.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_046603728.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046628956.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046613710.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046626236.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_046617412.1	12	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046626413.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046605054.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046617721.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046620020.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291	"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_046611491.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605654.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046628390.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046621050.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046606715.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_046615125.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_046614158.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046609421.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_046630488.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)"
XP_046617088.1	4	MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism"
XP_046606008.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046619417.1	13	Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852	"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"VEGFR2 mediated vascular permeability";"Macroautophagy"
XP_046628147.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046627125.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046629771.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046607686.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046629549.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608798.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046612251.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046618012.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046622301.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046605283.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_046608813.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046625570.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613434.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046617771.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_046609882.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046628905.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER"
XP_046603909.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046627212.1	6	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Phosphatidylinositol signaling system"
XP_046613504.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046612950.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046626314.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_046614527.1	6	MetaCyc: PWY-6364;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046606501.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_046615749.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046606518.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046608360.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046630276.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046615950.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046605463.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_046611650.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046620080.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616	"Thermogenesis";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046625577.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628119.1	11	Reactome: R-HSA-210744;Reactome: R-HSA-72163;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"mRNA Splicing - Major Pathway";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_046623181.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_046627250.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046610245.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046620778.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046627983.1	9	Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-9630222	"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate binding"
XP_046610848.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046626324.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_046626956.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610054.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046624697.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046623823.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046621850.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046625163.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046603855.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis"
XP_046606358.1	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046613249.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046628655.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046606911.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_046621969.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046603505.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046620244.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046611138.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046618371.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046630134.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046614156.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046608223.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046620044.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046620694.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046624382.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046624598.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629913.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046629563.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046620122.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046618201.1	15	Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-2559582	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)"
XP_046612255.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_046606005.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046605624.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046610618.1	14	MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_046617378.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046611863.1	44	KEGG: 04150+2.7.11.24;Reactome: R-HSA-444257;Reactome: R-HSA-9627069;Reactome: R-HSA-6802946;Reactome: R-HSA-2559585;Reactome: R-HSA-5675221;Reactome: R-HSA-456926;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-5654726;Reactome: R-HSA-3371453;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-5668599;Reactome: R-HSA-5654727;Reactome: R-HSA-879415;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-5654732;Reactome: R-HSA-8943724;Reactome: R-HSA-5654733;Reactome: R-HSA-202670;Reactome: R-HSA-5663213;Reactome: R-HSA-198753;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-5674499;Reactome: R-HSA-2559580;Reactome: R-HSA-6811558;Reactome: R-HSA-445144;Reactome: R-HSA-982772;Reactome: R-HSA-162658;Reactome: R-HSA-1295596;Reactome: R-HSA-170968;Reactome: R-HSA-112409;Reactome: R-HSA-2559582;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-375165;Reactome: R-HSA-2029482;Reactome: R-HSA-450341	"mTOR signaling pathway";"RSK activation";"Regulation of the apoptosome activity";"Signaling by moderate kinase activity BRAF mutants";"Oncogene Induced Senescence";"Negative regulation of MAPK pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"FCERI mediated MAPK activation";"Signal attenuation";"Negative regulation of FGFR1 signaling";"Regulation of HSF1-mediated heat shock response";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR2 signaling";"Advanced glycosylation endproduct receptor signaling";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR3 signaling";"Regulation of PTEN gene transcription";"Negative regulation of FGFR4 signaling";"ERKs are inactivated";"RHO GTPases Activate WASPs and WAVEs";"ERK/MAPK targets";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"Negative feedback regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signal transduction by L1";"Growth hormone receptor signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Spry regulation of FGF signaling";"Frs2-mediated activation";"RAF-independent MAPK1/3 activation";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"NCAM signaling for neurite out-growth";"Regulation of actin dynamics for phagocytic cup formation";"Activation of the AP-1 family of transcription factors"
XP_046609965.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046623803.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_046606842.1	11	Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631	"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility"
XP_046602926.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_046626862.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046623005.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_046607746.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046628852.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046613251.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046608408.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046629448.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-4641258	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"G2/M Checkpoints";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL"
XP_046619736.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046622907.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046613772.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046602900.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046613524.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046619413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617437.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046628555.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046617125.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
XP_046621946.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046608290.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046611730.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046625165.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046623177.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046625377.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046622905.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614526.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046603857.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046612980.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046628387.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046610180.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344	"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis"
XP_046621611.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_046623584.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Streptomycin biosynthesis"
XP_046605216.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046613814.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046605678.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_046624706.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046623288.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046623411.1	5	MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046602937.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046625642.1	6	Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-7717	"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_046613495.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046613374.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II"
XP_046603629.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046606680.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis"
XP_046627623.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_046613601.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_046609163.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046608712.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046624558.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046624235.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-6978	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II"
XP_046622904.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605876.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046614439.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046626914.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046627326.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046623359.1	5	Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_046603824.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046612653.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_046623063.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046615041.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046609311.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046604234.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046619824.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046605854.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046612414.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613266.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_046625564.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046625270.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046625023.1	9	Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115	"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_046616072.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA"
XP_046621674.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046604508.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046608519.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046621301.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_046612427.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046617388.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046609798.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046618987.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046602911.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046605209.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046627953.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_046608411.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046619993.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046610619.1	14	Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046618937.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046621637.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046629442.1	6	Reactome: R-HSA-5609978;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12	"Defective GALT can cause Galactosemia";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046625884.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046603947.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412	"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C"
XP_046626916.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606818.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333	"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated"
XP_046611552.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046615698.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_046612407.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046630486.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046622360.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046620731.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046626882.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046630227.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_046620329.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_046604237.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046624105.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046613055.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_046613671.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046619361.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046619514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046616079.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-427413	"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression"
XP_046626796.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046618461.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046613252.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046612386.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046605996.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_046614640.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046626395.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046624243.1	7	KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3	"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Thiamine metabolism"
XP_046603975.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046613330.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_046614721.1	20	Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942	"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Polymerase switching";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)"
XP_046629773.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046611238.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046625705.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046629473.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046610831.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_046620638.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046608584.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046614556.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_046615886.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046614173.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046626349.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046617492.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046628573.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046616800.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_046617354.1	7	KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716	"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046607597.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_046620375.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046607588.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation"
XP_046611628.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046611360.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624170.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046617008.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046619782.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625619.1	29	Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167200	"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046613491.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046624422.1	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_046619006.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046603987.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046627631.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046614892.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046627536.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046620637.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046622664.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046618042.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046618655.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629815.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046623539.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046628330.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_046605200.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244	"Integrin cell surface interactions";"NCAM1 interactions";"Signaling by PDGF";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Extracellular matrix organization"
XP_046625620.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72086	"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping"
XP_046621468.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046607885.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046616850.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046625103.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046616505.1	7	MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-5578999	"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_046612836.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046625706.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046623510.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046621354.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046609697.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046616119.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046602859.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_046615469.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046630118.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046620855.1	10	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Human papillomavirus infection";"Thermogenesis";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046622553.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610384.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046624861.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046618085.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046609253.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046612340.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_046613167.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046604045.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606813.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046611699.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1250347;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001	"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade"
XP_046615880.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_046619787.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_046611021.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046618185.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046618179.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046603064.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_046615119.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046622927.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046609933.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046610478.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046618958.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046619870.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_046621376.1	17	Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-6782135	"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER"
XP_046604695.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046622559.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046615874.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046624533.1	4	KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557	"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis"
XP_046606572.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046619386.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_046621672.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_046614224.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046607192.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046621092.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046628287.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046627632.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046602991.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046611123.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046609477.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046617479.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046627223.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_046623406.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046612282.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046621335.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046618831.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_046626813.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046612724.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046623284.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046614796.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046616500.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins"
XP_046607147.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046629871.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_046627268.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046630156.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046629769.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_046617039.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046621207.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046628902.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_046620349.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046611935.1	6	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_046603466.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046627564.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046617725.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_046609236.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046611606.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs"
XP_046623653.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046629795.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046620648.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_046611392.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046624478.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046611959.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_046615266.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046624477.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046605084.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_046617546.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046604917.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046630484.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046614259.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046626782.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_046610235.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046604489.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification"
XP_046623423.1	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_046621278.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_046608377.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046624384.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046623581.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046609184.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046610983.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046619829.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046607233.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_046620625.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602931.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_046619004.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046614931.1	20	MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_046620953.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046627733.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046605466.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_046619679.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046604648.1	12	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"DCC mediated attractive signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection"
XP_046622370.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046612368.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046615468.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046625898.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046624710.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046621083.1	13	MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes"
XP_046617822.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046626263.1	5	KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_046620690.1	24	Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-418594	"G-protein activation";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events"
XP_046607576.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046627080.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046627605.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046615126.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624842.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_046613955.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046624851.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046611759.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046602974.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046607180.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_046613635.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046610250.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046614644.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046625846.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046622880.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046626938.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046617902.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046613970.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-428543	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"EGFR downregulation";"DCC mediated attractive signaling";"Myogenesis";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1"
XP_046611776.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_046620793.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046626400.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046603980.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046611871.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046614234.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046611122.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046622262.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046610992.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex"
XP_046622259.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610129.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046610055.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046618657.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046628342.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046630382.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046611335.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046606544.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046612184.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_046605325.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046621774.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046614781.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046624241.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046619391.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046627799.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046609685.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_046629561.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046611242.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046603409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046602989.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046630237.1	57	Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236	"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"G2/M Checkpoints";"Neutrophil degranulation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046620984.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046621935.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_046616380.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding"
XP_046625161.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046607887.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046603232.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046625447.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606221.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046623664.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_046612048.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046623984.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046615053.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046616488.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046612770.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_046625362.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046618952.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046603553.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046627075.1	37	Reactome: R-HSA-3301854;Reactome: R-HSA-983170;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-204005;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9639288;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-191859	"Nuclear Pore Complex (NPC) Disassembly";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"COPII-mediated vesicle transport";"tRNA processing in the nucleus";"Mitotic Prometaphase";"MHC class II antigen presentation";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amino acids regulate mTORC1";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly"
XP_046608587.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046603732.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_046620789.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_046607982.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046615453.1	9	MetaCyc: PWY-5981;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I"
XP_046623711.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046603882.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046604205.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046627346.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046615408.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_046619007.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046628709.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_046615050.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046622577.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_046622921.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046606042.1	13	Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18	"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes"
XP_046606991.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046615274.1	14	MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_046614091.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046619506.1	12	Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1	"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"NRAGE signals death through JNK";"Human papillomavirus infection"
XP_046613033.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_046620591.1	18	MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7409	"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_046615240.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046628350.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_046616178.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046618440.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046627009.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046603503.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046619680.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_046609160.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_046627260.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046604799.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046615789.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046620145.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_046627262.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046618429.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046629826.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046604793.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046611977.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046627443.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046610149.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046621579.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046603062.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-6901	"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation"
XP_046626047.1	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874;Reactome: R-HSA-189483	"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I";"Heme degradation"
XP_046612951.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444	"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046623587.1	8	KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_046605964.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046615887.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046628426.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_046622281.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_046622619.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046603218.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046603775.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046622353.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046617348.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_046624673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046617042.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046623105.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046608404.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046611821.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046610846.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046616111.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_046615700.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_046619786.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046615871.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046629781.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046614649.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046616981.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046614611.1	12	Reactome: R-HSA-210744;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_046621151.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046624721.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046610647.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046622918.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046629290.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046605408.1	17	Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-2559585;Reactome: R-HSA-69231	"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"G0 and Early G1";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Oncogene Induced Senescence";"Cyclin D associated events in G1"
XP_046624147.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046622902.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_046627578.1	15	MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40	"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_046616356.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_046604957.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-174154	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"G2/M Checkpoints";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin"
XP_046627211.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605150.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046619630.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_046629094.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046616371.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_046606377.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046604160.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046606576.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046620202.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046629746.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046614209.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046620010.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046618300.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_046618426.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046606716.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046618338.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046623118.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046612596.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613765.1	11	Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046629852.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046629515.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046610372.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046627291.1	12	KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550	"Sulfur metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Monobactam biosynthesis";"Selenocompound metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_046612178.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046607617.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_046604153.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046619588.1	9	Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-8856828;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-5678895	"Ub-specific processing proteases";"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis"
XP_046614359.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_046622252.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046621303.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046609742.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257	"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN"
XP_046626201.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_046621446.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046628179.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046627894.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046623266.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046629367.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046615961.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046611199.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_046614154.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046627152.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_046611976.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046608015.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046613285.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046626742.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046604666.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046609794.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046606999.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins"
XP_046614153.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046617917.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_046614360.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046624277.1	39	Reactome: R-HSA-190322;Reactome: R-HSA-5654688;Reactome: R-HSA-1839122;Reactome: R-HSA-1839130;Reactome: R-HSA-6811558;Reactome: R-HSA-5654689;Reactome: R-HSA-5654221;Reactome: R-HSA-5654699;Reactome: R-HSA-5654719;Reactome: R-HSA-5673001;Reactome: R-HSA-2033519;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-190375;Reactome: R-HSA-5654720;Reactome: R-HSA-190373;Reactome: R-HSA-5654687;Reactome: R-HSA-5654700;Reactome: R-HSA-1257604;Reactome: R-HSA-8853338;Reactome: R-HSA-109704;Reactome: R-HSA-190371;Reactome: R-HSA-5654706;Reactome: R-HSA-5654227;Reactome: R-HSA-5654228;Reactome: R-HSA-5654219;Reactome: R-HSA-5654695;Reactome: R-HSA-5654727;Reactome: R-HSA-5654733;Reactome: R-HSA-190372;Reactome: R-HSA-5654732;Reactome: R-HSA-5655302;Reactome: R-HSA-2219530;Reactome: R-HSA-5654704;Reactome: R-HSA-5654710;Reactome: R-HSA-5655253;Reactome: R-HSA-5658623;Reactome: R-HSA-2033514;Reactome: R-HSA-5654726	"FGFR4 ligand binding and activation";"SHC-mediated cascade:FGFR1";"Signaling by activated point mutants of FGFR1";"Signaling by activated point mutants of FGFR3";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR1";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR4";"RAF/MAP kinase cascade";"Activated point mutants of FGFR2";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FGFR2c ligand binding and activation";"PI-3K cascade:FGFR4";"FGFR1c ligand binding and activation";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR2 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR3 point mutants in cancer";"PI3K Cascade";"FGFR3b ligand binding and activation";"FRS-mediated FGFR3 signaling";"Phospholipase C-mediated cascade, FGFR3";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade: FGFR1";"PI-3K cascade:FGFR2";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR4 signaling";"FGFR3c ligand binding and activation";"Negative regulation of FGFR3 signaling";"Signaling by FGFR1 in disease";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR3";"Signaling by FGFR2 in disease";"FGFRL1 modulation of FGFR1 signaling";"FGFR3 mutant receptor activation";"Negative regulation of FGFR1 signaling"
XP_046611060.1	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-2301	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis"
XP_046605233.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046625305.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_046625261.1	10	MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-6362;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;Reactome: R-HSA-1855167;Reactome: R-HSA-983231	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production"
XP_046608476.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046619107.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_046621608.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046616425.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046621394.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046609923.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046629641.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046624777.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046605990.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046614919.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046625283.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_046614018.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046609263.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-1187	"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine"
XP_046623476.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046611346.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046621296.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046629962.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_046613423.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_046608121.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046604022.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046624275.1	39	Reactome: R-HSA-5654689;Reactome: R-HSA-6811558;Reactome: R-HSA-1839130;Reactome: R-HSA-1839122;Reactome: R-HSA-190322;Reactome: R-HSA-5654688;Reactome: R-HSA-5654687;Reactome: R-HSA-5654712;Reactome: R-HSA-190375;Reactome: R-HSA-5654720;Reactome: R-HSA-190373;Reactome: R-HSA-2033519;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654719;Reactome: R-HSA-5654221;Reactome: R-HSA-5654699;Reactome: R-HSA-5654228;Reactome: R-HSA-5654227;Reactome: R-HSA-5654706;Reactome: R-HSA-190371;Reactome: R-HSA-109704;Reactome: R-HSA-8853338;Reactome: R-HSA-1257604;Reactome: R-HSA-5654700;Reactome: R-HSA-5654219;Reactome: R-HSA-5654727;Reactome: R-HSA-5654695;Reactome: R-HSA-5654732;Reactome: R-HSA-190372;Reactome: R-HSA-5654733;Reactome: R-HSA-5654710;Reactome: R-HSA-5654704;Reactome: R-HSA-2219530;Reactome: R-HSA-5655302;Reactome: R-HSA-5654726;Reactome: R-HSA-2033514;Reactome: R-HSA-5658623;Reactome: R-HSA-5655253	"PI-3K cascade:FGFR1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by activated point mutants of FGFR3";"Signaling by activated point mutants of FGFR1";"FGFR4 ligand binding and activation";"SHC-mediated cascade:FGFR1";"Downstream signaling of activated FGFR1";"FRS-mediated FGFR4 signaling";"FGFR2c ligand binding and activation";"PI-3K cascade:FGFR4";"FGFR1c ligand binding and activation";"Activated point mutants of FGFR2";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR4";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR2";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade, FGFR3";"FRS-mediated FGFR3 signaling";"FGFR3b ligand binding and activation";"PI3K Cascade";"Signaling by FGFR3 point mutants in cancer";"PIP3 activates AKT signaling";"FRS-mediated FGFR2 signaling";"Phospholipase C-mediated cascade: FGFR1";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR2";"Negative regulation of FGFR3 signaling";"FGFR3c ligand binding and activation";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR1 in disease";"Negative regulation of FGFR1 signaling";"FGFR3 mutant receptor activation";"FGFRL1 modulation of FGFR1 signaling";"Signaling by FGFR2 in disease"
XP_046604856.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046621443.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046623667.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_046618427.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046603334.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046616243.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046630072.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV"
XP_046625502.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_046606260.1	25	Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-8951936;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8939245;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8931987;Reactome: R-HSA-8939256;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8939243;Reactome: R-HSA-8941858;Reactome: R-HSA-8941333;Reactome: R-HSA-8939242;Reactome: R-HSA-8941284;Reactome: R-HSA-8877330;Reactome: R-HSA-8939902;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8939247;Reactome: R-HSA-8949275	"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 regulates p14-ARF";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates chondrocyte maturation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX2 expression and activity";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 Regulates Immune Response and Cell Migration"
XP_046630133.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046622166.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046628639.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046615309.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046609088.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046607881.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046609990.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046611169.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603954.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046620005.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046609575.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046615922.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046606491.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_046625399.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046613875.1	5	MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20	"Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes"
XP_046617160.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046626535.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046630232.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046623246.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605498.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_046627670.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046629969.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_046608300.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612534.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046627592.1	6	KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52	"Methane metabolism";"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism"
XP_046611979.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046619056.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_046608710.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_046612758.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046620603.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046616875.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_046606774.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046622007.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046611740.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046630503.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_046605638.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046612224.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046611518.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046620428.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046625162.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618737.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046614876.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046617566.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046611698.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046625714.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387	"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Photosynthesis";"Insulin receptor recycling"
XP_046616793.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_046622302.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046618770.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046609390.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046620379.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046619587.1	9	Reactome: R-HSA-5689880;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-5678895	"Ub-specific processing proteases";"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis"
XP_046626875.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046629229.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046621362.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6372	"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_046629416.1	6	Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046612392.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling"
XP_046614128.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046622841.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046614182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046619055.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046611013.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_046603404.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046624847.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046613637.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046624015.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046606401.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5610785	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Downstream TCR signaling";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome"
XP_046612688.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046612012.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_046614957.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"Gap junction assembly";"Aggrephagy";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046624483.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_046617396.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046621442.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046616974.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046625700.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_046626534.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046617377.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046629542.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046615438.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_046616527.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629369.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629131.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_046606469.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046623697.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046610837.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046622213.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046624178.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046618203.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046626547.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046606714.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046609687.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046613676.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex"
XP_046625287.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_046615990.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046616781.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046618597.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046603903.1	17	Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-1169091;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-4086398	"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"Activation of NF-kappaB in B cells";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"Ca2+ pathway"
XP_046609793.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046608420.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046615279.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046613500.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046615993.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046617037.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046620724.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046627445.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046621841.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2	"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism"
XP_046604373.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046606075.1	17	Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8853884	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX"
XP_046604215.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046614949.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046615750.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046623087.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_046623898.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176407	"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046603670.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184	"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046607610.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8943723	"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation"
XP_046611613.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid"
XP_046628170.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628	"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046604304.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046607267.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046616188.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046620622.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046630338.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630275.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_046626929.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046617041.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046610481.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling"
XP_046606651.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_046607380.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046607864.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046603183.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_046613477.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046623732.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis"
XP_046620619.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046627214.1	6	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle"
XP_046605315.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046629177.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12	"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis"
XP_046615699.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_046619779.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046630108.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046620503.1	8	MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695	"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Neutrophil degranulation"
XP_046624862.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046605115.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046607206.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046605717.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-1251985;Reactome: R-HSA-2660826;Reactome: R-HSA-193692	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Growth hormone receptor signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Regulated proteolysis of p75NTR"
XP_046614748.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046612483.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046618882.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046611519.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046607666.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_046621297.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046615230.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046622732.1	7	Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204	"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol"
XP_046609547.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046610574.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046611502.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046623853.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046626331.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_046628971.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046611103.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046621814.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_046611551.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046618399.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046605535.1	32	Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167246	"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_046621135.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279	"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_046603401.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046626741.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046622424.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_046620358.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046617096.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628505.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046603448.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046620816.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096	"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation"
XP_046609231.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_046624200.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046602934.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_046629140.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046618396.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-1489509	"Ca2+ pathway";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling"
XP_046606784.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046616435.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046630562.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046618856.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046616666.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046622110.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628417.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Downstream TCR signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
XP_046629253.1	11	Reactome: R-HSA-9627069;Reactome: R-HSA-1268020;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"Mitochondrial protein import";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_046610498.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046609415.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-4381;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5367	"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis"
XP_046610074.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_046620123.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046616966.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046607697.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046606737.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046620403.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046610876.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046624848.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046603554.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046628509.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046608654.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046611617.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_046617901.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046608575.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046625810.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_046619061.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046619175.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046625196.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046622466.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046610477.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_046613869.1	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_046618727.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046622755.1	22	MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-7727;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation"
XP_046604518.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046617291.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_046630533.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046611177.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046614222.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046603700.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046625580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046613641.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046616682.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046612389.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046623346.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046617398.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046623763.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606777.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046626811.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046614176.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046609821.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046607002.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046604481.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603738.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_046619084.1	4	KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism"
XP_046625352.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation"
XP_046612943.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046627044.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_046626125.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046608304.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046622946.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046623946.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046624905.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046611713.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046625565.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_046618187.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046620864.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046607653.1	11	MetaCyc: PWY-6383;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-5123;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;Reactome: R-HSA-191273;MetaCyc: PWY-6859;MetaCyc: PWY-7560;MetaCyc: PWY-7391;MetaCyc: PWY-7102	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis";"Methylerythritol phosphate pathway II";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)"
XP_046619952.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046620859.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622569.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection"
XP_046626504.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_046605211.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_046607648.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"D-galactose detoxification"
XP_046610279.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046614750.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046614427.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046603833.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046607125.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046625058.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_046606937.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046617674.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046613826.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046611235.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046628884.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046608185.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046606041.1	13	MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II"
XP_046622273.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046629453.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046610850.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046626112.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046608513.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962	"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex"
XP_046624034.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-5531	"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_046609083.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_046605808.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-110331;Reactome: R-HSA-9608287	"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Cleavage of the damaged purine";"Defective MUTYH substrate binding"
XP_046607034.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046614554.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_046613054.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046622494.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046617488.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_046629825.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046604197.1	14	MetaCyc: PWY-181;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-3841;MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1	"Photorespiration ";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Methane metabolism";"Folate polyglutamylation";"Glycine betaine degradation I";"Folate transformations II (plants)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Metabolism of folate and pterines";"Cyanoamino acid metabolism"
XP_046627159.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046611942.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046620956.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046609766.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046629749.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_046613278.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_046622303.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046607082.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046621158.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046629742.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046604170.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046626943.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046619404.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613306.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046615622.1	8	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_046613645.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046605787.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_046625913.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046626162.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046614631.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046615920.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_046629393.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046625235.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046626851.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046629778.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046611474.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046621320.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046626870.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046614452.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_046604581.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046614782.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046609051.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046603955.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046603436.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046620795.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"Macroautophagy";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_046617618.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_046628400.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-6811558	"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046625976.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046625748.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046625504.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_046608288.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046624935.1	7	MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;Reactome: R-HSA-70635	"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Urea cycle"
XP_046625745.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_046621356.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046602964.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_046623588.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046622374.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046628850.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-381033	"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046603376.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046607709.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046626129.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046607370.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_046603930.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046626930.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046621846.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046614170.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625088.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046619491.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046614258.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046612099.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046626722.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_046625974.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046619842.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046627263.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046618666.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046611512.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines"
XP_046618202.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046618604.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046628080.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046624736.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046615211.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"Neutrophil degranulation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046615062.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046604698.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046627604.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_046621338.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046609822.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046617951.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_046615570.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046614249.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046619858.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782135	"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Polymerase switching";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Dual incision in TC-NER"
XP_046605428.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046623068.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_046621867.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046607952.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607343.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046611546.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046613159.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-975634	"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport"
XP_046602925.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046608846.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046630475.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046612287.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046611761.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_046626587.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625243.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046609043.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046615118.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046611340.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046617426.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_046621984.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046621372.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Aggrephagy";"Gap junction assembly";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs"
XP_046605898.1	28	Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5685938	"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Meiotic recombination";"Dual incision in TC-NER";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)"
XP_046622867.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046617429.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046620700.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_046615010.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_046613234.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046613447.1	11	Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-388841	"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"PD-1 signaling";"Regulation of IFNA signaling";"Platelet sensitization by LDL";"Regulation of IFNG signaling";"Costimulation by the CD28 family"
XP_046618823.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046607507.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_046624876.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2	"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_046612299.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046619642.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046613663.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046609795.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046628744.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046610381.1	6	KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_046615931.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046604348.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046605962.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_046610762.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046603628.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046622715.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046628626.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046630145.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046603630.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046618874.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046624711.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046622689.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046607421.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046617752.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046608359.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046624085.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_046626354.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046628137.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_046623858.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046630492.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_046604171.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652	"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_046624227.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression"
XP_046611256.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_046606688.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628503.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046625249.1	33	Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453	"HCMV Early Events";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response"
XP_046605453.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation"
XP_046619635.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046612859.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_046624162.1	5	Reactome: R-HSA-4755579;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046613231.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046617400.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046627634.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_046608591.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046624931.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046622454.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046626233.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046627897.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046604754.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046629196.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046621051.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046621594.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606705.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046622798.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337	"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_046611037.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_046611034.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_046618343.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046623164.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046624180.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046621741.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046628577.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046622099.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046622385.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection"
XP_046626850.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046623756.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046603741.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046613492.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046610393.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_046614333.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046612877.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_046617097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602927.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046615416.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612406.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046623811.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046615242.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046604458.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_046625182.1	27	KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5610783;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-399956;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-8939902;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5674400;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-75815	"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Degradation of GLI2 by the proteasome";"Human papillomavirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CRMPs in Sema3A signaling";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"B-WICH complex positively regulates rRNA expression";"Regulation of RUNX2 expression and activity";"Thermogenesis";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ubiquitin-dependent degradation of Cyclin D"
XP_046629330.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_046606952.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_046604915.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046629868.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046617192.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_046614225.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ion transport by P-type ATPases";"Ion homeostasis";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_046623121.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046617035.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046604772.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046610182.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_046605525.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046621488.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046620321.1	20	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Thermogenesis";"Regulation of PTEN gene transcription";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling"
XP_046615714.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_046620201.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046610133.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046622560.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046622749.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046629091.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046618039.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046613480.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046625453.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046622376.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046612866.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_046628401.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-432142	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL"
XP_046625346.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046616255.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046618349.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046618029.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"G2/M Checkpoints";"Neutrophil degranulation";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21"
XP_046624670.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629540.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612612.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046609650.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046610254.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046606812.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046608278.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_046603394.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046625578.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627325.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622903.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046630268.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_046606537.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Activation of RAC1"
XP_046608795.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046607835.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046626793.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046604996.1	52	Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167243	"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_046605336.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046607627.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046615375.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046612437.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046605407.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-2173796	"Pre-NOTCH Transcription and Translation";"G0 and Early G1";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_046627990.1	52	Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152	"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046616657.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046623896.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046615726.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046617676.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046606410.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_046617345.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046618997.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046609792.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy"
XP_046613243.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046621565.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_046619551.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046630377.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046612647.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_046608301.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046619511.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046623194.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046612662.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046629834.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046613648.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046619095.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046626127.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046616273.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_046627390.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046608187.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046609777.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046603998.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046610911.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046624669.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614935.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_046624934.1	7	MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635	"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Canavanine degradation";"Arginine and proline metabolism";"Urea cycle"
XP_046609416.1	31	Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7664	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)"
XP_046611067.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046618249.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046626918.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046617708.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046621403.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046612098.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046623822.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046609778.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046620733.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_046621466.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046617431.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046623652.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046608922.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046618741.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046604730.1	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315	"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_046616573.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046607382.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046603298.1	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-75109;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-8055	"Ether lipid metabolism";"Synthesis of PE";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis"
XP_046616524.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046621255.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046605469.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-180585	"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G"
XP_046622505.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046622391.1	11	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_046623844.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_046622373.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046623009.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_046611855.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046620697.1	13	Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"HSF1 activation";"Josephin domain DUBs";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Ovarian tumor domain proteases";"Protein methylation"
XP_046619942.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA"
XP_046621402.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046606770.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046615458.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046629736.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046618656.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613986.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046614085.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046612615.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046621293.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046613232.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046610268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046625733.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_046628496.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046614888.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046618822.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation"
XP_046626224.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046627199.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5687128	"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_046619983.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046612947.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046617236.1	12	KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417	"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046623409.1	5	KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046616546.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_046625177.1	9	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046603816.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046620043.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046613352.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046602982.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_046629249.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046629360.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046610595.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046616849.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046604198.1	14	KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-3661-1	"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"Methane metabolism";"Folate polyglutamylation";"Glycine betaine degradation I";"Folate transformations I";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Glycine betaine degradation II (mammalian)"
XP_046609705.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046606045.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046609796.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046619415.1	13	Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Macroautophagy";"VEGFR2 mediated vascular permeability";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_046618339.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046624326.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046604049.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046610836.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination"
XP_046629295.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046606521.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046603023.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046625236.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046606471.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2	"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism"
XP_046616660.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046611712.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_046615785.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046612320.1	22	Reactome: R-HSA-70171;MetaCyc: PWY-5659;MetaCyc: PWY-3801;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-6992;MetaCyc: PWY-622;MetaCyc: PWY-5514;MetaCyc: PWY-5054;MetaCyc: PWY-7347;MetaCyc: PWY-7238;MetaCyc: PWY-5384;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263;Reactome: R-HSA-5628897	"Glycolysis";"GDP-mannose biosynthesis";"Sucrose degradation II (sucrose synthase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis / Gluconeogenesis";"Chitin biosynthesis";"Neutrophil degranulation";"1,5-anhydrofructose degradation";"Starch biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"D-sorbitol biosynthesis I";"Sucrose biosynthesis III";"Sucrose biosynthesis II";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis";"TP53 Regulates Metabolic Genes"
XP_046615508.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_046627529.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046621302.1	3	Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046617671.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046616976.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_046621598.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628553.1	40	Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-6796648	"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046618402.1	12	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes"
XP_046627194.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9022692	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity"
XP_046610177.1	10	Reactome: R-HSA-5609977;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046610687.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046620104.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046617010.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046610089.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046622684.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046624619.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046628491.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_046621868.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046622896.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE"
XP_046609132.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046613746.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046603904.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_046617850.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation"
XP_046616427.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046611887.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_046605241.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046609405.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046604021.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046617659.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046604195.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046612979.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046604921.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046626279.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism"
XP_046623038.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046623036.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046627780.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_046606329.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046605529.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046606268.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046624728.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046619828.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046629038.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_046621772.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046626342.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046628402.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion"
XP_046615028.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046615973.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046611703.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046619860.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046621839.1	10	MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112	"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification"
XP_046621361.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046630516.1	58	Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5689901;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733	"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Metalloprotease DUBs";"ER-Phagosome pathway";"Degradation of AXIN";"Interleukin-1 signaling";"G2/M Checkpoints";"Neutrophil degranulation";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_046613938.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046613602.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046621214.1	5	MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046609932.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613556.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046614478.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046611934.1	6	KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046613471.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046609193.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046609998.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046607736.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083	"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions"
XP_046607635.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046619336.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_046611155.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046619810.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046623629.1	24	Reactome: R-HSA-5218920;Reactome: R-HSA-5607764;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-5625740;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"CLEC7A (Dectin-1) signaling";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"RHO GTPases activate PKNs";"Thermogenesis";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"mTOR signaling pathway";"Human cytomegalovirus infection";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"PI3K-Akt signaling pathway";"Integrin signaling";"VEGFR2 mediated cell proliferation";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"RSK activation";"PIP3 activates AKT signaling"
XP_046618698.1	10	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation"
XP_046629566.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608639.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046607598.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_046623690.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046606144.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046621633.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046610874.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046612189.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_046619696.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_046603377.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046625996.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849;MetaCyc: PWY-7394	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Urate conversion to allantoin II"
XP_046610590.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046615620.1	8	Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_046608305.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612283.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046616638.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_046610577.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046620966.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046609476.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046606807.1	15	Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-111465	"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Apoptotic cleavage of cellular proteins"
XP_046614296.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046604486.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism"
XP_046619371.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603429.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046626113.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046620991.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046603341.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046619933.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607615.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_046609047.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046609723.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046622379.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046620191.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046630473.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_046609962.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046629222.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046607207.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046607232.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_046629419.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046604838.1	8	KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901	"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_046616151.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046609106.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046617477.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046615936.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615250.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613472.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046621289.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046608410.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046613607.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_046603677.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046610597.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046625912.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046606006.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046621773.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation"
XP_046608903.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046611926.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046624192.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046622796.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-735	"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis"
XP_046623248.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046620939.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046615828.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046629077.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_046610413.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_046630342.1	18	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482925	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PG"
XP_046615460.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046622425.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046617250.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046627544.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046620730.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_046626925.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046623437.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046615505.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975	"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_046622567.1	9	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection"
XP_046613490.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046620715.1	13	MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1	"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis"
XP_046629356.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603744.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046616743.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_046624471.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046620989.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046626350.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046611084.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046618879.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_046614016.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046625178.1	27	Reactome: R-HSA-196299;Reactome: R-HSA-75815;Reactome: R-HSA-5358752;Reactome: R-HSA-5674400;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-8939902;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5250924;Reactome: R-HSA-399956;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5467348;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-3371453;Reactome: R-HSA-4641262;KEGG: 04151+2.7.11.1;Reactome: R-HSA-195253;KEGG: 05170+2.7.11.1	"Beta-catenin phosphorylation cascade";"Ubiquitin-dependent degradation of Cyclin D";"T41 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Thermogenesis";"S45 mutants of beta-catenin aren't phosphorylated";"Regulation of RUNX2 expression and activity";"Relaxin signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"B-WICH complex positively regulates rRNA expression";"CRMPs in Sema3A signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"Truncations of AMER1 destabilize the destruction complex";"Human cytomegalovirus infection";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Regulation of HSF1-mediated heat shock response";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI3K-Akt signaling pathway";"Degradation of beta-catenin by the destruction complex";"Human immunodeficiency virus 1 infection"
XP_046620732.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046623590.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046608668.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046630444.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_046620061.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046621657.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046608029.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046610578.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_046623037.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046614353.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_046613687.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046605046.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046612372.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046603978.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046622154.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046624286.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046628912.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046613870.1	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_046612032.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046604499.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046622791.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
XP_046617838.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_046619383.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046629869.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection"
XP_046607754.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046619069.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_046616341.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_046615200.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046629831.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046628490.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_046614819.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_046611745.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046607964.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046618973.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046630193.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046628701.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046617952.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-202040	"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G-protein activation"
XP_046615623.1	8	Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046621535.1	13	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II"
XP_046606074.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628871.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046613644.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046612003.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046613784.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046604329.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046629404.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_046605875.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046624397.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046608139.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046616965.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046619789.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569	"HDACs deacetylate histones";"PPARA activates gene expression";"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046612889.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"MHC class II antigen presentation";"Intraflagellar transport"
XP_046606573.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046629035.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046615210.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046629666.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046615286.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046610096.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046615457.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046617214.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_046619078.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_046609991.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616487.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_046620250.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping"
XP_046602999.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046607211.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046616983.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046606009.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_046610594.1	14	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-1632852;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Macroautophagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_046630385.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046625436.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046604834.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046614833.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_046622622.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046624735.1	12	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_046617718.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046612397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046611031.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046629246.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046603950.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_046629436.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_046628910.1	6	Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046613169.1	40	Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046610480.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling"
XP_046614797.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046624012.1	6	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-8876198	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"RAB GEFs exchange GTP for GDP on RABs"
XP_046618864.1	10	Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742	"Recycling pathway of L1";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RSK activation";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"
XP_046612891.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport";"MHC class II antigen presentation"
XP_046618722.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614814.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046629298.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_046617640.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046606805.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046615709.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046626158.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_046605629.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046619949.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046627896.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_046615724.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_046609319.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688	"Signal transduction by L1";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL"
XP_046619988.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046627344.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046624893.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046629168.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046622261.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046619991.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046618221.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046614826.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046629613.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046609493.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_046603461.1	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046611107.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046608412.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046619969.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046622046.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose"
XP_046620392.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046617722.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_046606892.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108	"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046628476.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046605365.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613021.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046629299.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046629212.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618934.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046607387.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_046607833.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046604068.1	6	Reactome: R-HSA-191273;Reactome: R-HSA-446199;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_046611237.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046627966.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046626404.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046624896.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046630378.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046627282.1	12	KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4	"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfur metabolism";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism"
XP_046616497.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_046626401.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination"
XP_046607639.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046613382.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-194313;Reactome: R-HSA-195399	"Platelet degranulation";"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization"
XP_046626184.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046605534.1	32	Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-167160	"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_046614975.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046609679.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046611874.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046626714.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_046622924.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046618299.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046609961.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046611877.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046626385.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_046602980.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_046615061.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046629606.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046616677.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046609613.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436	"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"MHC class II antigen presentation";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046608400.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046609655.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046618351.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046619022.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046626131.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046605874.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046609733.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616167.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046623909.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_046625640.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046622263.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_046620954.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046611937.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
XP_046610127.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046611717.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_046612547.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046607650.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046618984.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046618622.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046626908.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046615948.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622901.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_046622390.1	11	Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"p38MAPK events";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_046625371.1	3	Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193	"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046628735.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046612333.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938	"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_046603561.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046616676.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046620692.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis"
XP_046611774.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046611045.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_046603974.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046611889.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_046623688.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046628851.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046606577.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_046628855.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046604517.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046622764.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046603648.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046620326.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046622308.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046625987.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_046617298.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046611795.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046613850.1	18	Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events"
XP_046608421.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046613666.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046625671.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_046612767.1	7	Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Packaging Of Telomere Ends";"Meiotic synapsis";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_046617237.1	12	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism"
XP_046612070.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046627945.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_046619098.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046629336.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_046620642.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608	"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III"
XP_046617164.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046607604.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569	"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046610249.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046627178.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618667.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046617116.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation"
XP_046623766.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_046624385.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046603460.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046613643.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046603179.1	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_046620712.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-7659	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis"
XP_046619418.1	13	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Macroautophagy";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation"
XP_046617948.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_046607032.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046617632.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046619995.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046626876.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046612944.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046615924.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_046623199.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046606938.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046616649.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046606403.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046604307.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_046620471.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_046622270.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046621537.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046605489.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046608367.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046620599.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046604209.1	16	Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-190873	"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Formation of annular gap junctions";"LDL clearance";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"Gap junction degradation"
XP_046615621.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_046622345.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046610921.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046620985.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046616181.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046606893.1	9	Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168	"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_046609512.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046624818.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046629599.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046605552.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046617748.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046619564.1	9	Reactome: R-HSA-9656255;Reactome: R-HSA-110330;Reactome: R-HSA-9656256;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-110331	"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine"
XP_046612242.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046616681.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046611621.1	7	KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-7625;MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11	"Glycerophospholipid metabolism";"Synthesis of PI";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_046620861.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046626194.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046606840.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046611402.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_046607836.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603112.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046630518.1	42	MetaCyc: PWY-7779;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7656;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-6945;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5109;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-5177;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17	"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"2-methylpropene degradation";"Geraniol degradation";"Fatty acid degradation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Spodoptera littoralis pheromone biosynthesis";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Androstenedione degradation";"Fatty acid salvage";"Toluene degradation";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"Limonene and pinene degradation";"Propanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Glutaryl-coa degradation";"Benzoate degradation";"alpha-Linolenic acid metabolism"
XP_046619931.1	16	Reactome: R-HSA-5603037;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-5602498;Reactome: R-HSA-6811558;Reactome: R-HSA-975155;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-166058	"IRAK4 deficiency (TLR5)";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"Interleukin-1 signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_046618911.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606495.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046606411.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_046613246.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046624111.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046610589.1	10	MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5839	"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis"
XP_046621534.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046608413.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046620263.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046604468.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046617163.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046626359.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046622298.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046627389.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_046617954.1	24	Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-8964616	"Ca2+ pathway";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G-protein activation";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42"
XP_046604552.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046606935.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046620259.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046619742.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046613502.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616122.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046604019.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046604105.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046605226.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046618214.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017	"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046606489.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_046616656.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046628948.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046603933.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-4641258	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Neutrophil degranulation";"G2/M Checkpoints";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL"
XP_046603197.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_046623348.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046622828.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_046611870.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046616428.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_046612544.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_046614630.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046619871.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046616821.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046603152.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695	"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation"
XP_046622444.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046620133.1	8	MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;Reactome: R-HSA-74217	"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Purine salvage"
XP_046615018.1	7	MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_046608100.1	13	MetaCyc: PWY-7039;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system"
XP_046610654.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046625326.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_046629643.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046621505.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046617829.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046616783.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046605517.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046618661.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046629142.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046609858.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046611991.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046605839.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046626034.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16	"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway"
XP_046604976.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_046627800.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046620657.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046626072.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046627608.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046624224.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046628707.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_046609690.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046607115.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046624009.1	6	Reactome: R-HSA-8876198;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710	"RAB GEFs exchange GTP for GDP on RABs";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy"
XP_046621985.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046608646.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046624883.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046630223.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-167590	"Ion channel transport";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation"
XP_046605880.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046624550.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046624399.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046608493.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Neutrophil degranulation";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription"
XP_046605563.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046613646.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046612008.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534	"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"UCH proteinases";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4"
XP_046609930.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046620243.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046625264.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_046613138.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046620851.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_046618365.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046619187.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_046629872.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046616381.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding"
XP_046606116.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046628029.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046617860.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046605198.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919	"Laminin interactions";"Signaling by PDGF";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Integrin cell surface interactions";"Extracellular matrix organization";"ECM proteoglycans";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Crosslinking of collagen fibrils"
XP_046618875.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_046610988.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_046614429.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046611971.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046607745.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612563.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046602935.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046612313.1	11	Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-5695;Reactome: R-HSA-8851680	"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions"
XP_046626208.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046624709.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046618361.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046617118.1	6	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046624467.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_046611104.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046614365.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_046624116.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046607228.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627113.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046624311.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046620976.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046611515.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975	"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA"
XP_046612552.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046606400.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046620800.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_046606816.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046615935.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046609860.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046624118.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046605944.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046617647.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046606637.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins"
XP_046605948.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046624377.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046617105.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046621482.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_046617496.1	6	MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism"
XP_046624430.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_046620209.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046613488.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046615624.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)"
XP_046629000.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_046621828.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046608110.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046622990.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046611473.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046606912.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_046626104.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046614856.1	33	Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-69231;Reactome: R-HSA-73863	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination"
XP_046603216.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046624625.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046620328.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_046605350.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_046625554.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_046604722.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046614562.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_046614058.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_046604213.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046602958.1	7	KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596	"Drug metabolism - other enzymes";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I"
XP_046618378.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046615873.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046611395.1	12	Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046624174.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046621367.1	10	MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046621216.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046629171.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046614055.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046629009.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046609845.1	5	KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6614	"One carbon pool by folate";"Folate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis"
XP_046628126.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046620004.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046630335.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629818.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046607253.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046622760.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046611638.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046630578.1	5	Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5205685	"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy"
XP_046625220.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046616973.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046607430.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046624872.1	30	KEGG: 04926+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-6804758;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-8941332;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-1358803;Reactome: R-HSA-199418;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-9614399;Reactome: R-HSA-6804759;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;Reactome: R-HSA-389513;Reactome: R-HSA-8948751;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-211163;Reactome: R-HSA-198693;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69656;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-111447;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Activity through Acetylation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"RUNX2 regulates genes involved in cell migration";"Thermogenesis";"Regulation of TP53 Degradation";"Downregulation of ERBB2:ERBB3 signaling";"Negative regulation of the PI3K/AKT network";"Human immunodeficiency virus 1 infection";"Cyclin E associated events during G1/S transition";"Regulation of localization of FOXO transcription factors";"Regulation of TP53 Activity through Association with Co-factors";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"CTLA4 inhibitory signaling";"Regulation of PTEN stability and activity";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the nucleus";"PI3K-Akt signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Activation of BAD and translocation to mitochondria";"Human cytomegalovirus infection"
XP_046622352.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046626539.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_046628535.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046612702.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046607870.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610878.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625172.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613664.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046629952.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046610554.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603560.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046604456.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)"
XP_046603967.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046612898.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046627944.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046617874.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046620501.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046621129.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046621584.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046623966.1	10	MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-3841	"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)"
XP_046609239.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046624236.1	12	MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5856	"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_046629029.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610636.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046618363.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046628987.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-532668;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_046615046.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046606910.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046624626.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046604638.1	6	MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908;Reactome: R-HSA-196819	"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism"
XP_046625454.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046628493.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_046618108.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046625222.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046605460.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_046620699.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)"
XP_046630248.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046604669.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046622856.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046625689.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_046613914.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046629358.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612353.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046613527.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046603134.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046628352.1	7	MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-73817;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205	"Inosine 5'-phosphate degradation";"Purine metabolism";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_046612346.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-167238	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation"
XP_046618736.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046611480.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_046630443.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence"
XP_046614273.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692	"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity"
XP_046610264.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046619452.1	18	Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;MetaCyc: PWY-7511;Reactome: R-HSA-5693554;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Protein ubiquitination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046610211.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046627437.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046603506.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_046625585.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480	"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"LDL clearance";"VLDL assembly";"Platelet sensitization by LDL";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Scavenging by Class A Receptors"
XP_046606918.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_046607600.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408	"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_046614352.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571	"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation"
XP_046624196.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046612664.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046615204.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046627112.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046613369.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046624473.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046608518.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046621217.1	5	MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046628455.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_046614308.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046620371.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938	"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"Platelet sensitization by LDL";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"LDL clearance";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand"
XP_046617542.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046617556.1	14	Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2122948	"Neutrophil degranulation";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_046629632.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046609515.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046614254.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046609363.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"UCH proteinases";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1"
XP_046630235.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046603566.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane"
XP_046627273.1	12	Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Selenate reduction";"Purine metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Sulfur metabolism"
XP_046613881.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046629953.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046613626.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046622044.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586	"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_046624985.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046617861.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046628439.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046606494.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_046622233.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046629008.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046608368.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046627180.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046612904.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-390450	"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC"
XP_046607209.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046621355.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046613338.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046626396.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_046623731.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_046624894.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046620210.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046606995.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_046612433.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046618277.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_046605809.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9608290;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-9630222	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate processing";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate binding"
XP_046613214.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046611444.1	14	Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-500657;MetaCyc: PWY-8052;Reactome: R-HSA-399997;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Ca2+ pathway";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046616336.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_046627547.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3270619;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046606801.1	15	Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-111465	"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins"
XP_046628289.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046608504.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046629552.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046621357.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046613634.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046626572.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046618302.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046621333.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046623974.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046625238.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046627607.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046618893.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-5620912;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Anchoring of the basal body to the plasma membrane";"RHO GTPases Activate Formins"
XP_046628768.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046614719.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046628792.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_046611764.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_046626410.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046626978.1	7	Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_046628674.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046613312.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046613096.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_046603384.1	4	Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046625583.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046602928.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_046603582.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046603583.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046624013.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046607172.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_046628066.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046605214.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046603673.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_046615011.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_046611038.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex"
XP_046607084.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046608660.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046623710.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046619610.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_046622703.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046611134.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046620689.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046618341.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046623354.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046622378.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046609913.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046623129.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046607735.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046616489.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046618652.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046622061.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_046613831.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046616383.1	4	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_046618186.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046615045.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046619683.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_046611129.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046622256.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046613967.1	19	Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5663220	"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"EGFR downregulation";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling";"Myogenesis";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins"
XP_046619243.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046619945.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046615051.1	4	Reactome: R-HSA-379716;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557	"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_046621336.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046617353.1	11	Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169	"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis"
XP_046620479.1	8	MetaCyc: PWY-6556;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7193	"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I"
XP_046610611.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_046614175.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046626345.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046620319.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046623705.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618045.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046608811.1	13	MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046618863.1	10	Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"RSK activation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046605430.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG"
XP_046605206.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046611902.1	29	Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-6796648;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-5693554;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803207;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of DNA Repair Genes";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Relaxin signaling pathway";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Thermogenesis";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046607582.1	4	MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20	"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism"
XP_046613335.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046612603.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046611120.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046605409.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-111448;Reactome: R-HSA-9616222;Reactome: R-HSA-69231;Reactome: R-HSA-2559585;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Pre-NOTCH Transcription and Translation";"G0 and Early G1";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Activation of NOXA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Cyclin D associated events in G1";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046623192.1	5	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_046626340.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046604020.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613242.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046615662.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_046613861.1	18	Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922	"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI"
XP_046630015.1	10	MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_046617476.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046613145.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046627528.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046620343.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046618306.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046630498.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_046610260.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046616164.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046620801.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_046609274.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046606635.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046623368.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046611933.1	6	MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism"
XP_046615980.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046617279.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046603299.1	14	MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-75109;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis II"
XP_046624845.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046604310.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-180746	"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein"
XP_046613730.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046617142.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046607217.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046617714.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046620204.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046614531.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381038	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes"
XP_046612715.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046629361.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606989.1	10	Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_046603942.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_046623222.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_046628914.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046608620.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046623496.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046630234.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046606182.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_046605882.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046627549.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_046627959.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046624618.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046624432.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046620344.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046605464.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046626126.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046617815.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_046620312.1	20	Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165159	"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Relaxin signaling pathway";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"Thermogenesis";"Macroautophagy";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling"
XP_046620096.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046615079.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046605410.1	17	Reactome: R-HSA-1538133;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-9616222;Reactome: R-HSA-111448	"G0 and Early G1";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria"
XP_046618362.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046613963.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046615530.1	5	KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_046618689.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_046615034.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI"
XP_046611609.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046604937.1	5	Reactome: R-HSA-110381;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210	"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046630074.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046615477.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046621785.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046609992.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046622438.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046608394.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046624314.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_046615049.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046604645.1	12	Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"Relaxin signaling pathway";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046623963.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046611999.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046626872.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046627374.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_046626054.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046622240.1	11	KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187	"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_046614532.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_046627597.1	29	KEGG: 00980+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5079;MetaCyc: PWY-5057;MetaCyc: PWY-7111;KEGG: 00625+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5076;MetaCyc: PWY-5082;MetaCyc: PWY-7118;KEGG: 00071+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-7396;MetaCyc: PWY-6802;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-6587;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-6342;MetaCyc: PWY-5751	"Metabolism of xenobiotics by cytochrome P450";"Serotonin degradation";"L-phenylalanine degradation III";"L-valine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"Chloroalkane and chloroalkene degradation";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"L-leucine degradation III";"L-methionine degradation III";"Chitin degradation to ethanol";"Fatty acid degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol I";"Butanol and isobutanol biosynthesis (engineered)";"Salidroside biosynthesis";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"Retinol metabolism";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"Acetaldehyde biosynthesis I";"Noradrenaline and adrenaline degradation";"Phenylethanol biosynthesis"
XP_046618731.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046622508.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046615285.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046613591.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_046622133.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046626106.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046616979.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046608406.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046627434.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046617409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046621967.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_046611998.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046605752.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046629417.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046609475.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622276.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046603940.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_046614010.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046623358.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046627616.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_046630394.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046622130.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046626879.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046613345.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046630564.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046612796.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins"
XP_046614475.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_046621206.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046602922.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_046612727.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046618735.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046605858.1	18	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7226	"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_046623962.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046625358.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046617537.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046606039.1	14	MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-5690	"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)"
XP_046622699.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_046603354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618720.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046613535.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046626234.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_046622372.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619096.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046621641.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616658.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046614853.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046607219.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046606126.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046619639.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046619194.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046621830.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046610379.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_046603246.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046615201.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046605364.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046617624.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046620018.1	20	MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136	"Jasmonic acid biosynthesis";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046622697.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046603419.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046617996.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-196780;Reactome: R-HSA-163765	"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Glyoxylate assimilation";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression"
XP_046621318.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046616578.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046628107.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_046607200.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046615782.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046630334.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046604384.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_046621634.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616117.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046613598.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_046622348.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046622109.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628563.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046622310.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046622894.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046610212.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046619226.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046604854.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046630143.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612068.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046613654.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046622700.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_046627996.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046615396.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612965.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_046629300.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_046626239.1	4	MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188	"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_046605490.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046622355.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046613515.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_046605965.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736	"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors"
XP_046621279.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_046622963.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046608858.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046610186.1	3	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_046625523.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627246.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783	"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome"
XP_046621347.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046625914.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046627323.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622640.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046606811.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046613253.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046630384.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046614180.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046605886.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046613885.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046617281.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046627986.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72649	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Translation initiation complex formation"
XP_046619996.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046621776.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription"
XP_046625151.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_046623007.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_046629735.1	7	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-429947	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Deadenylation of mRNA"
XP_046628754.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046620938.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_046629055.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046612535.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046608227.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046623188.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_046611065.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606532.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046627525.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046611174.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2132295	"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Gap junction assembly";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"MHC class II antigen presentation"
XP_046613270.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046611030.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046624803.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046612530.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_046621815.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_046608571.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046603552.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046604670.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046618988.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046610745.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046608218.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_046629832.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046613383.1	3	Reactome: R-HSA-194313;Reactome: R-HSA-114608;Reactome: R-HSA-195399	"VEGF ligand-receptor interactions";"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization"
XP_046629918.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046619197.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046609322.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046611627.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_046611603.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_046613041.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046614916.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046627338.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling"
XP_046602985.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046615027.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046614178.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046623663.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_046620325.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046616244.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046610761.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046616839.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
XP_046605188.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046620106.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046606526.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046607827.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046610269.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615503.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046605989.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046619161.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201	"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis"
XP_046619073.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751	"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Neutrophil degranulation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity"
XP_046608665.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046619603.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628441.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Purine metabolism";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_046612183.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046619200.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046609204.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_046624210.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046628427.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046619935.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607959.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_046614255.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046615393.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046625245.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046625281.1	6	KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046616116.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046609049.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046618605.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046622462.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046618598.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_046609050.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_046625379.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046620796.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy"
XP_046609754.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046614647.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_046618868.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046623178.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046611361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046602923.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046628703.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684	"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state"
XP_046605562.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046607178.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046613359.1	7	MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7886	"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_046617707.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046626853.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046620241.1	18	KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1	"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism"
XP_046610094.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618699.1	10	Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23	"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Sphingolipid metabolism"
XP_046610093.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046605385.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046630366.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046616152.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_046629558.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_046626673.1	9	MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Biotin transport and metabolism"
XP_046626953.1	8	Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724	"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription"
XP_046626940.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046604005.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046623265.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627601.1	6	KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52	"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"Methane metabolism"
XP_046611875.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046624451.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046613370.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_046622698.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_046620862.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046627233.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046626053.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046629900.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_046603074.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_046615260.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046609888.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_046607831.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_046620711.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7736	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Stellatic acid biosynthesis"
XP_046612315.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;Reactome: R-HSA-74259;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_046609543.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)"
XP_046617138.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046613053.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_046608873.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046618006.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627569.1	15	KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003	"Purine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol"
XP_046619838.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_046612191.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_046605003.1	13	MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046609997.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046619594.1	9	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Aggrephagy"
XP_046628148.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046607699.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046611537.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046618204.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046623884.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_046608733.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Repression of WNT target genes"
XP_046615829.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046604283.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046613776.1	5	Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-6168;MetaCyc: PWY-5523	"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_046608673.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046629908.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046614054.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_046606588.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046629743.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046617344.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_046604832.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046606666.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_046613271.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271	"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046603148.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695	"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation"
XP_046628061.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046609881.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046619375.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612157.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046618548.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046612072.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_046623104.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046604769.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046622415.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8934593	"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity"
XP_046626933.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046624405.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046606570.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046619414.1	13	Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"Macroautophagy";"HSF1-dependent transactivation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling"
XP_046611446.1	14	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-500657;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;Reactome: R-HSA-112043;Reactome: R-HSA-418217;Reactome: R-HSA-434316;Reactome: R-HSA-399997;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"Inositol phosphate metabolism";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"PLC beta mediated events";"G beta:gamma signalling through PLC beta";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule"
XP_046615939.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046617538.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046615934.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046618344.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046626153.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046620691.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D"
XP_046616522.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046627622.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation"
XP_046603338.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046605993.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_046603984.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046617235.1	12	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism"
XP_046628418.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Interleukin-1 signaling";"G2/M Checkpoints";"Neutrophil degranulation";"Orc1 removal from chromatin";"UCH proteinases";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
XP_046617238.1	12	MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_046620955.1	29	Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453	"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Meiotic recombination";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response"
XP_046625008.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046619790.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537	"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_046611061.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363	"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_046623814.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046627761.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046607963.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046610091.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046611119.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046609473.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046604505.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046612991.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046613218.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046623360.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046606591.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046623591.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046624107.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046620172.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516	"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin"
XP_046622838.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046622753.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-6958;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7049;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_046604890.1	4	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046628565.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046617485.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_046620242.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046620430.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046610684.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_046627439.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046617803.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046613000.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_046626177.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_046623819.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046629851.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046613531.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046602984.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_046623666.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_046621282.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_046618729.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046613766.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-5693571;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonhomologous End-Joining (NHEJ)";"Human papillomavirus infection";"Human cytomegalovirus infection";"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046622789.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events"
XP_046628128.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046613957.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046612967.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046604311.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
XP_046623975.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046603397.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046602959.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-5695;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis"
XP_046607088.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046623083.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046623434.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046605147.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_046624319.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612354.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046617029.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046618233.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_046621739.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046630337.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046609790.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046618550.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046625911.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_046617583.1	3	KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_046606589.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046615245.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046626646.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046625782.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046625560.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_046608338.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046623340.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046621447.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046617736.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_046628027.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046622149.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046624117.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046627770.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046624794.1	6	KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Drug metabolism - other enzymes";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_046621738.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046615257.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_046622681.1	7	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"PPARA activates gene expression";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046619504.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046628675.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046609587.1	8	MetaCyc: PWY-5740;MetaCyc: PWY-5738;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47	"GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046622771.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046615481.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046603378.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046622648.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046621291.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_046615092.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_046618572.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046605144.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046616995.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046606814.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046603170.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046618356.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046611610.1	42	Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-73772;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-606279;Reactome: R-HSA-5250924;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-171306;Reactome: R-HSA-5625886	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"HDACs deacetylate histones";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged purine";"DNA methylation";"Deposition of new CENPA-containing nucleosomes at the centromere";"B-WICH complex positively regulates rRNA expression";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_046621932.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes"
XP_046629725.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046605098.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_046611200.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_046620451.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625317.1	7	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22	"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_046611492.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603297.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052	"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PE";"Ether lipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_046625380.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046621788.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046603612.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046622354.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046620936.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_046622912.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046610382.1	5	KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234;MetaCyc: PWY-6123	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I"
XP_046608293.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046622692.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046626355.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046616836.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination"
XP_046622849.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046622235.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_046615464.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046615268.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_046620013.1	20	MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136	"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_046622122.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046605885.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046616780.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046617071.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046607747.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046626316.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_046617719.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046617804.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046609254.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046617134.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046607670.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791	"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_046626974.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046625910.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046604553.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046620167.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046610010.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046616802.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046617460.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046619030.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046612148.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046615729.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_046612957.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046611631.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046615792.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046611884.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046614332.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692	"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity"
XP_046613520.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046629547.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046625345.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046611062.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_046624899.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046624449.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_046610247.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046625900.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046623658.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_046616792.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046612614.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046626226.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046604007.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_046620103.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046620393.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046628681.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046619164.1	11	Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201	"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Estrogen-dependent gene expression";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046609348.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_046617023.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046603997.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046603905.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046605335.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046613484.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046615022.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046621636.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046623462.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046603926.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046619100.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046626718.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_046622550.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619597.1	9	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-9646399;Reactome: R-HSA-5689880	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Aggrephagy";"Ub-specific processing proteases"
XP_046622657.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-76042	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046613505.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607328.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_046625256.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046615521.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046605769.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events"
XP_046617711.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046605559.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046604142.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046612341.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046623855.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046622750.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046616461.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"G alpha (q) signalling events";"Platelet degranulation";"Post-translational protein phosphorylation"
XP_046628173.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046628523.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046604734.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046625917.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408	"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism"
XP_046617402.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046629548.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046622589.1	12	MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5872	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_046610056.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046626123.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046625000.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046627192.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046603563.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane"
XP_046621481.1	8	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_046612801.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_046613255.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046620777.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046628753.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046606553.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_046624228.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568	"ESR-mediated signaling";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase"
XP_046614451.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046624233.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II"
XP_046610605.1	14	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism"
XP_046621317.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046602936.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_046627941.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-2453864	"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Retinoid metabolism and transport";"Retinoid cycle disease events"
XP_046630271.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046622458.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046624138.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046616564.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046610732.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736	"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Kinesins";"Gap junction assembly";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors"
XP_046626816.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046620735.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046608418.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046624922.1	14	MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667	"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I"
XP_046606742.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046624932.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046614436.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046612158.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046626227.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046610929.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046603340.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046624771.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046604322.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046617539.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046627348.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046609808.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_046617032.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046604732.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046609281.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046619498.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046623702.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046608838.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-4381;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5367	"Fatty acid biosynthesis";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis"
XP_046613954.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046624035.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609232.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046610612.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_046621609.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046612310.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046604214.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046620852.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_046628973.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_046607396.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046607390.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046614861.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046625378.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046609843.1	7	MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6614;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3	"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_046619934.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046617677.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_046618905.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046629437.1	6	KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose catabolism"
XP_046615917.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_046621322.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046603981.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046615983.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046624815.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_046623263.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046603571.1	6	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane"
XP_046618189.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046619816.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046613179.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108	"RORA activates gene expression";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046613985.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046615072.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607932.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_046623602.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046625111.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046626847.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046628370.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_046623191.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_046610377.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046623765.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619318.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046624168.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046620025.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046629513.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046616253.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046619989.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046622837.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_046613657.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046603374.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046628530.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046621547.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_046621208.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_046605530.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046609755.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046615088.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_046626880.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046623062.1	16	Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-912631;Reactome: R-HSA-194840	"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"RET signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"Regulation of signaling by CBL";"Rho GTPase cycle"
XP_046608183.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046614815.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046628510.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046630111.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046605114.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046607243.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046620019.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046630493.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_046618240.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046612396.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622343.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046613791.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624472.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046627548.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_046622568.1	9	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_046622638.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046613496.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046621453.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046616083.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_046623706.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046623675.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_046615091.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"
XP_046628275.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046622519.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046618391.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046617897.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_046615353.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622666.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_046606836.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896	"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases"
XP_046628495.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046614389.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants"
XP_046618765.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046623856.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046603951.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_046630368.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046620413.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046617427.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046614362.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants"
XP_046612825.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Platelet degranulation";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046608720.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes"
XP_046607470.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly"
XP_046622685.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_046627673.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948	"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants"
XP_046629474.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046620592.1	18	Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801	"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS"
XP_046607333.1	25	Reactome: R-HSA-4086398;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-381771;Reactome: R-HSA-163359	"Ca2+ pathway";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G-protein activation";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon signaling in metabolic regulation"
XP_046615040.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046629782.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_046625173.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_046613980.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046623384.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_046609994.1	4	MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_046604680.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046620363.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046616521.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046603138.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis"
XP_046602912.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046626463.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_046614320.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046603983.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046621580.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046626935.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046626921.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046630499.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046617638.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046607381.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046626235.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_046623808.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046618985.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046604437.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_046603990.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046620934.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_046621844.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046603043.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046622267.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046607360.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615087.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6"
XP_046620135.1	8	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611	"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V"
XP_046606690.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046610923.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046609631.1	3	Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins"
XP_046607411.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046626033.1	6	Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046623267.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046614032.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046622522.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046623945.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046607818.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046612849.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation"
XP_046607108.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046629095.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046630386.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046622989.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046620940.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046617362.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_046618646.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046626341.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046630409.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_046620253.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046630088.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046620961.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046617669.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046619242.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046619440.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046606707.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046615290.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_046611172.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628901.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_046615994.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046605222.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046617762.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Deadenylation of mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046619121.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_046627255.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046610579.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_046615888.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046608362.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046621374.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046611032.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046621441.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046603957.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046604107.1	11	Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665	"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells"
XP_046620362.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606357.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046612685.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046608137.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-202733	"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"LDL clearance";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall"
XP_046627093.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046621554.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)"
XP_046625946.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046625242.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_046616160.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046620935.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_046618498.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046610746.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046627524.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046612177.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046615362.1	8	Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324	"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046613215.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046622702.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_046628028.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046614666.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046612136.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046615082.1	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_046609384.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046606571.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046615793.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046626733.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_046613308.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046615310.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046624976.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046603526.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046605851.1	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_046629799.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046604777.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046622511.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046630455.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101	"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation"
XP_046626514.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_046618903.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046610926.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613590.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236	"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"UCH proteinases";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_046615727.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046629286.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046625994.1	4	MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Purine metabolism"
XP_046630481.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046618849.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"G0 and Early G1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046617540.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046613820.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400	"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER"
XP_046629955.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046623555.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046614800.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046612845.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046626280.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism"
XP_046604232.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046611511.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695	"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation"
XP_046605327.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046609993.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046623390.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_046612430.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046619497.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046622665.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_046618359.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046608794.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046626863.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046605208.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046618182.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046630491.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
XP_046612918.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399	"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy"
XP_046615478.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046628048.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046606808.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046624395.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046627751.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_046629355.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628799.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046621253.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046626736.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046630349.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046614062.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046628152.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046625907.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046624779.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046628699.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046612723.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046627538.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568	"Regulation of TP53 Activity through Phosphorylation";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046621254.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046618746.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046629591.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046625473.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_046620006.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046628791.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046614877.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046612551.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046610185.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046614343.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046608517.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046612683.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046625899.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046615467.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046620105.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624904.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046625001.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046611767.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_046608680.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046613097.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_046612966.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046626779.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046615617.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)"
XP_046618962.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046616566.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046603698.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046625836.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_046606461.1	6	KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22	"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism"
XP_046629219.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046606953.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_046627492.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046617355.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046618740.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046614344.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046608419.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046613237.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046618011.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046611825.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046611002.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046622127.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046605869.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_046613794.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046627345.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
XP_046614172.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046630563.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_046606044.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046612102.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046612929.1	31	Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7664	"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)"
XP_046628515.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046617441.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_046603780.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046621988.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046619586.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829	"Aggrephagy";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Chaperone Mediated Autophagy"
XP_046607646.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_046630391.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046605524.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046614354.1	5	Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046606029.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046605109.1	19	MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5913;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Methane metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms"
XP_046610844.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046625517.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046624666.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046621771.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation"
XP_046609406.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_046612602.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046618350.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046613659.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046618554.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046627609.1	30	Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167152	"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046630525.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6783310;Reactome: R-HSA-983168	"Protein ubiquitination";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046604498.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046619701.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_046604707.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046629797.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046609386.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046612964.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046619596.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5627083	"Aggrephagy";"Ub-specific processing proteases";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking"
XP_046630375.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046610496.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046615280.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)"
XP_046620426.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046623831.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046603832.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046624951.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046619241.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046604956.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Neutrophil degranulation";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex"
XP_046618112.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046622428.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046630469.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857	"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_046612926.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase"
XP_046618489.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046612476.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624622.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046613533.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046614890.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046623860.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046620945.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046626116.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046613229.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046612298.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046612879.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932	"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules"
XP_046605488.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046612490.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046613619.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046620331.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046626814.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046609289.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046607834.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613354.1	7	MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)"
XP_046611239.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046617119.1	7	KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201	"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis"
XP_046611393.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046605986.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046622056.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046630278.1	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
XP_046614658.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_046630247.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046626553.1	16	Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046605312.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046628606.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046628004.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046615461.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046623518.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_046612338.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_046609044.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046610492.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046627777.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_046617631.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046623987.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046606219.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046628279.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046628064.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046623436.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613108.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046618826.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation"
XP_046603718.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-168315;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Inhibition of Host mRNA Processing and RNA Silencing";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_046630270.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_046614802.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046618368.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046612605.1	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_046606040.1	13	MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18	"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes"
XP_046619444.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046619058.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_046608407.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046626671.1	9	KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-6142	"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_046613969.1	19	Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-525793	"EGFR downregulation";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"Myogenesis"
XP_046614313.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046625561.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046617070.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046620339.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046616818.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046624747.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046604874.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_046607967.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046604097.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046605313.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046621624.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_046616058.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046619090.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046608374.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046609375.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046603699.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_046618239.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046617036.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046605042.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_046617936.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046615339.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046613653.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046626737.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046614239.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-877300	"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Interferon gamma signaling"
XP_046623854.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046623724.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_046613793.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046623189.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_046607727.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046630274.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_046615930.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046622984.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046624209.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_046622460.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046624060.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046630339.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630336.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046626868.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046630410.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046608951.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046607579.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046614862.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_046612595.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046603564.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_046625858.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_046616175.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046615790.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046620374.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046627735.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046613156.1	5	MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7185	"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I"
XP_046621642.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046624122.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046625906.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046625343.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046614306.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046626810.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046622916.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046627114.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046606586.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628533.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_046605213.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046617430.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_046617352.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046619712.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046606191.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046604362.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046627412.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046621245.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046620076.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046610575.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046616176.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046605236.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938	"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)"
XP_046621947.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046605212.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_046603135.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046612946.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046606261.1	25	Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-9018519;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8936459;Reactome: R-HSA-8939902;Reactome: R-HSA-8939247;Reactome: R-HSA-8949275;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-8951936;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-8931987;Reactome: R-HSA-8939245;Reactome: R-HSA-8939256	"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"Estrogen-dependent gene expression";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"RUNX3 regulates p14-ARF";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in WNT signaling"
XP_046625904.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046607410.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046607388.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_046607696.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046603407.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046626939.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046607580.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046603082.1	5	KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046621663.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046615261.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046629770.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes"
XP_046618881.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046617143.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046608141.1	13	KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;Reactome: R-HSA-74259;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7206	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_046605687.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-167590	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation"
XP_046614447.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046619002.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046627527.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046629293.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046624075.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046612532.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_046613435.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046616647.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046628489.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_046623353.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046615077.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046621330.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046626942.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046604774.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046619629.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_046629750.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046617364.1	4	Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_046629784.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046607630.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046603245.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046623813.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046610987.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046607375.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_046622920.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046603558.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046630407.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_046607212.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_046623796.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046609444.1	57	Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8939902	"Downstream TCR signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Interleukin-1 signaling";"Orc1 removal from chromatin";"G2/M Checkpoints";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity"
XP_046630226.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_046607363.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_046623393.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-3301854	"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly"
XP_046627092.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046622688.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046628694.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046626855.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_046612846.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046617567.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046604875.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046605696.1	7	KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7219;MetaCyc: PWY-7234	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_046630371.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046612878.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_046626812.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046625002.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046617359.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_046614338.1	10	Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Carnitine metabolism";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs"
XP_046618665.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046615912.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046611420.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046612436.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046605520.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046609929.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624470.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046607675.1	11	KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-5154;Reactome: R-HSA-500753;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5	"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046612850.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046627940.1	6	Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-975634	"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Retinoid metabolism and transport"
XP_046629279.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046609042.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046618188.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_046616416.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046620383.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046609264.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-1187	"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine"
XP_046628388.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046621933.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes"
XP_046626124.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046627704.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_046618145.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046619158.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046624698.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046615693.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046612256.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59"
XP_046613350.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046629026.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046612440.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046615117.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_046623781.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_046611323.1	8	Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-4086398;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870	"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Ca2+ pathway";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins"
XP_046624115.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_046612097.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046614220.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046616906.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046613361.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046617836.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_046608138.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825	"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis"
XP_046610712.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome"
XP_046624969.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046613924.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_046624874.1	30	Reactome: R-HSA-389513;Reactome: R-HSA-1257604;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-69202;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;Reactome: R-HSA-8876198;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69656;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-111447;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-198693;Reactome: R-HSA-389357;Reactome: R-HSA-6804758;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-9634638;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-8941332	"CTLA4 inhibitory signaling";"PIP3 activates AKT signaling";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"RAB GEFs exchange GTP for GDP on RABs";"PI3K-Akt signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Activation of BAD and translocation to mitochondria";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the nucleus";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Activity through Acetylation";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thermogenesis";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"RUNX2 regulates genes involved in cell migration"
XP_046617739.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"HIV Transcription Initiation";"HATs acetylate histones";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046606206.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046611337.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046609682.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046619806.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046606827.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-111465	"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins"
XP_046624110.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046626724.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_046627010.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046611873.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046606693.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046612069.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046611995.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046606000.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046611020.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046623960.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046607213.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046608923.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_046611165.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046618161.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046620643.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608	"Purine catabolism";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III"
XP_046629532.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-611105	"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport"
XP_046618890.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046614262.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046629752.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046622814.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612482.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046627874.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_046618439.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046608662.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046609238.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046609168.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
XP_046617919.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils"
XP_046613686.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046607087.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046629631.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046613528.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_046617487.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_046605483.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046613373.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_046613586.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_046609065.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_046622906.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_046624172.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_046619269.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046609202.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_046629114.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046629741.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616114.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER"
XP_046619864.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046612598.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046618013.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046623657.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_046624814.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_046615563.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046615991.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046628047.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046610057.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_046614857.1	33	Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046615278.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046608633.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142	"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins"
XP_046612644.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603	"Iron uptake and transport";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases"
XP_046609210.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis"
XP_046613390.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046607871.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046618872.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046604051.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046604776.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046626885.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046615507.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046621631.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046611980.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046614190.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism"
XP_046628750.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046618999.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046606831.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046617005.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046618082.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046617950.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_046624078.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins"
XP_046604470.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046608849.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
XP_046618171.1	3	MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60;Reactome: R-HSA-5666185	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046620850.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_046613675.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex"
XP_046621360.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046606915.1	11	Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"PKA activation";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_046625688.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_046618364.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046617327.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_046611639.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_046621859.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046621536.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046616528.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603646.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-168315;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Inhibition of Host mRNA Processing and RNA Silencing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_046621900.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046613184.1	10	Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153	"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"mTOR signaling pathway"
XP_046618738.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046612972.1	7	KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4	"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Mevalonate degradation";"Butanoate metabolism"
XP_046619761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046615554.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046611938.1	6	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046630435.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_046621256.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046624859.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_046620506.1	18	KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642	"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation"
XP_046607701.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046618830.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_046619254.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046613592.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046604094.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046612920.1	23	Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398	"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G-protein activation";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway"
XP_046615968.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046609995.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046610350.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046614428.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046615882.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_046606073.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046619026.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046625055.1	10	Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells"
XP_046623438.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046603068.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose"
XP_046615347.1	13	KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1	"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_046621546.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046609649.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606310.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046607956.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046614129.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046620717.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7736	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis"
XP_046610674.1	13	MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046613844.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046623301.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_046618850.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-2173796	"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_046627534.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614351.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046612827.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955	"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046622132.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046623448.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_046615299.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619592.1	9	Reactome: R-HSA-5678895;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-8856828;Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-5689880	"Defective CFTR causes cystic fibrosis";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"Clathrin-mediated endocytosis";"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy";"Ub-specific processing proteases"
XP_046621944.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046618649.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046626035.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_046611541.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046622257.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606846.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001	"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade"
XP_046605697.1	7	KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7219;MetaCyc: PWY-7234	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_046614603.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046618110.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046615454.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_046614076.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_046603844.1	7	MetaCyc: PWY-7118;MetaCyc: PWY-7854;MetaCyc: PWY-7295;MetaCyc: PWY-6969;MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9	"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism"
XP_046618109.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046619335.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
XP_046609474.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046607602.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593	"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity"
XP_046611543.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046612331.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938	"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_046606524.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046628005.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046619237.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_046629541.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046617935.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046630457.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046625168.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046624316.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation"
XP_046627122.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046618231.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_046623662.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_046624830.1	13	KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation"
XP_046603567.1	6	Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system"
XP_046625255.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046625452.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_046623002.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_046612410.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_046604254.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046623229.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046604141.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_046603114.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605878.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046606993.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046623275.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046604679.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_046630406.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_046627410.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_046629554.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046630273.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_046615609.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046604502.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046626715.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_046609034.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046626455.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046616239.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046611932.1	6	KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046613489.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046627435.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046623841.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_046607432.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046627110.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046606543.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046622254.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046607631.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046626777.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046622992.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046606948.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046627109.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046629947.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_046628918.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046605505.1	4	KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48	"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_046616242.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046622468.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046619354.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046611994.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046619168.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211945	"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Phase I - Functionalization of compounds"
XP_046613368.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046603413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628457.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_046630238.1	57	Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128	"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"Neutrophil degranulation";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling"
XP_046609407.1	9	Reactome: R-HSA-68616;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex"
XP_046618913.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046622346.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046621341.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046616713.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046621612.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046620695.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046616795.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_046622362.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046608797.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046613864.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_046611572.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046604037.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046619207.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_046625296.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination"
XP_046620240.1	18	MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_046618724.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_046623654.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046604550.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046623060.1	16	Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499	"Rho GTPase cycle";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"RET signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane"
XP_046608172.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046623529.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046604855.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046618821.1	5	MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis"
XP_046608190.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046623980.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046629560.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046615071.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046608361.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046628003.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046617423.1	8	MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16	"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Synthesis of PG";"T cell receptor signaling pathway"
XP_046618596.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046607729.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046613658.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046603647.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046615546.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_046608145.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046602914.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046609282.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046606865.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis"
XP_046616001.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046616015.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_046622734.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_046621281.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_046609063.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046628640.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046604629.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046605118.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046621971.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046620696.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046603991.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046624376.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046605813.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046608165.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046618401.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483	"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs"
XP_046625212.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046609910.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_046606238.1	13	Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1	"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection"
XP_046627672.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046606004.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046618086.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046611573.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046625059.1	11	MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4	"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_046604955.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046606701.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629724.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046616804.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046605411.1	17	Reactome: R-HSA-1912408;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-2559580;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-9616222;Reactome: R-HSA-69231;Reactome: R-HSA-2559585;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-2173796	"Pre-NOTCH Transcription and Translation";"G0 and Early G1";"G1/S-Specific Transcription";"Oxidative Stress Induced Senescence";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Cyclin D associated events in G1";"Oncogene Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_046625968.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046621169.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046622034.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046609391.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046619780.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046604165.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046607698.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046623812.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046619393.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617930.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_046607587.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_046614807.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046616555.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046615288.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_046610475.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046616659.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046612806.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046609173.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism"
XP_046624208.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046629545.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046608258.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046621664.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046621344.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046611167.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622600.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046603524.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046622650.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046606249.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)"
XP_046616794.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046627148.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046606630.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046603510.1	5	KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-6168;MetaCyc: PWY-7863	"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis"
XP_046628238.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_046622512.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046629498.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046623992.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046617817.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046625440.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046629169.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046603743.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_046619641.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046615654.1	12	Reactome: R-HSA-173599;MetaCyc: PWY-6527;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9	"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism"
XP_046622113.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046614105.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046612204.1	3	KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100;Reactome: R-HSA-71262	"Lysine degradation";"L-carnitine biosynthesis";"Carnitine synthesis"
XP_046618114.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046614917.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046615916.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046629544.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046608667.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046610781.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation"
XP_046613605.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_046627127.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046603342.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_046619859.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1"
XP_046610710.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046624813.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046629284.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046629719.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046629371.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046628814.1	6	Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-381033	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046617115.1	4	MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_046603911.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_046630447.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_046606511.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046620618.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046626228.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046602986.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046624423.1	7	KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_046603639.1	15	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_046610179.1	10	MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;Reactome: R-HSA-70370	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism"
XP_046611709.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046610183.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046606778.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046629833.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046613233.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046606841.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046624392.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046604088.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_046624944.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046611520.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046617554.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618087.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046624011.1	6	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-8876198;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"RAB GEFs exchange GTP for GDP on RABs";"Budding and maturation of HIV virion"
XP_046629056.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046609681.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046605349.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_046628740.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046619678.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_046617012.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046612328.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_046630390.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046618184.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046612693.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046608242.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046619183.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046615484.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046614873.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046611391.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046608140.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046605333.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046630472.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_046623862.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046613984.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046610711.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends"
XP_046620161.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046604435.1	14	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
XP_046617216.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_046616972.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046624789.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046612104.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046603149.1	5	Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695	"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation"
XP_046611124.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046609167.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Gap junction assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events"
XP_046629195.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046614555.1	5	KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism"
XP_046623949.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_046616984.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046624113.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046610835.1	17	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046613334.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046620892.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046610265.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614474.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046603958.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618099.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046610090.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046606054.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_046615612.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_046620142.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046629068.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046619751.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628672.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046625646.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046615289.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_046605353.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_046615872.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046612982.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046617158.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046623089.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046607726.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046608688.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HCMV Early Events";"Aggrephagy";"Gap junction assembly";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"MHC class II antigen presentation"
XP_046623350.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_046624237.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5872	"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_046615969.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046606493.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_046627024.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046617043.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046610880.1	4	Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_046629266.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_046604441.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_046618442.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046606653.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_046618569.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630436.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_046627236.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046616190.1	6	KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_046629291.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046616411.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046626877.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046605781.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046619987.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046615516.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_046609203.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_046611885.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046630006.1	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221	"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis"
XP_046614419.1	18	Reactome: R-HSA-1482925;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism"
XP_046622258.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046609372.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046611505.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046619800.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046615474.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046627802.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036	"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II"
XP_046626528.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046611741.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046606681.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046622937.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046607205.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_046622389.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007	"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"p38MAPK events"
XP_046623407.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046606376.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046617596.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046625056.1	10	Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942	"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition"
XP_046612166.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_046616927.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046606634.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046611961.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046621596.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046610292.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5651801	"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair"
XP_046611630.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046610370.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046621365.1	10	MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism"
XP_046605482.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046630071.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046621847.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046629954.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046623204.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_046611046.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_046619191.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046614828.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046612203.1	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_046616333.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046628500.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046626821.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046628751.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046628386.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_046629551.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046610052.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046603312.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046624154.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046606790.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-111465	"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins"
XP_046608299.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046609966.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046617104.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046618230.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_046625398.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046626326.1	8	MetaCyc: PWY-5723;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-71336	"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway"
XP_046620003.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046611136.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046604188.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603463.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046619130.1	182	Reactome: R-HSA-168638;Reactome: R-HSA-975144;Reactome: R-HSA-5675482;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-2559585;Reactome: R-HSA-1253288;Reactome: R-HSA-6804760;Reactome: R-HSA-179409;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-72764;Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-901032;Reactome: R-HSA-72706;Reactome: R-HSA-8941858;Reactome: R-HSA-168928;Reactome: R-HSA-5632684;Reactome: R-HSA-5684264;Reactome: R-HSA-1236974;Reactome: R-HSA-72689;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-1799339;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-6807004;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8948747;Reactome: R-HSA-8939902;Reactome: R-HSA-9645460;Reactome: R-HSA-187577;Reactome: R-HSA-8866652;Reactome: R-HSA-8856828;Reactome: R-HSA-72649;Reactome: R-HSA-9636383;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-8849469;Reactome: R-HSA-6804757;Reactome: R-HSA-2173796;Reactome: R-HSA-156827;Reactome: R-HSA-6804756;Reactome: R-HSA-6781823;Reactome: R-HSA-175474;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-69231;Reactome: R-HSA-5675221;Reactome: R-HSA-5689896;Reactome: R-HSA-912631;Reactome: R-HSA-6791226;Reactome: R-HSA-8863795;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-9013973;Reactome: R-HSA-192823;Reactome: R-HSA-936440;Reactome: R-HSA-2672351;Reactome: R-HSA-5693607;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-5357956;Reactome: R-HSA-4641257;Reactome: R-HSA-3322077;Reactome: R-HSA-72695;Reactome: R-HSA-162588;Reactome: R-HSA-450302;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-6783310;Reactome: R-HSA-2122947;Reactome: R-HSA-174113;Reactome: R-HSA-5696395;Reactome: R-HSA-156902;Reactome: R-HSA-1169408;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8866654;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-6782210;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-110314;Reactome: R-HSA-445989;Reactome: R-HSA-5205685;Reactome: R-HSA-1358803;Reactome: R-HSA-5676590;Reactome: R-HSA-9013507;Reactome: R-HSA-5362768;Reactome: R-HSA-5696397;Reactome: R-HSA-1236382;Reactome: R-HSA-201681;Reactome: R-HSA-2173788;Reactome: R-HSA-975110;Reactome: R-HSA-8951664;Reactome: R-HSA-975163;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-2173791;Reactome: R-HSA-2408557;Reactome: R-HSA-917729;Reactome: R-HSA-174184;Reactome: R-HSA-937042;Reactome: R-HSA-5654727;Reactome: R-HSA-9615710;Reactome: R-HSA-977225;Reactome: R-HSA-450408;Reactome: R-HSA-937039;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-5689901;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-168927;Reactome: R-HSA-9033241;Reactome: R-HSA-5685942;Reactome: R-HSA-5689877;Reactome: R-HSA-5687128;Reactome: R-HSA-2173795;Reactome: R-HSA-3134975;Reactome: R-HSA-182971;Reactome: R-HSA-936964;Reactome: R-HSA-2894862;Reactome: R-HSA-2559580;Reactome: R-HSA-69541;Reactome: R-HSA-8876493;Reactome: R-HSA-110320;Reactome: R-HSA-9014325;Reactome: R-HSA-75815;Reactome: R-HSA-2122948;Reactome: R-HSA-2559582;Reactome: R-HSA-917937;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-5357905;Reactome: R-HSA-174490;Reactome: R-HSA-2565942;Reactome: R-HSA-5654726;Reactome: R-HSA-174084;Reactome: R-HSA-8875360;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-5696394;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-6781827;Reactome: R-HSA-9646399;Reactome: R-HSA-4641263;Reactome: R-HSA-975956;Reactome: R-HSA-5656121;Reactome: R-HSA-532668;Reactome: R-HSA-5656169;Reactome: R-HSA-450321;Reactome: R-HSA-937041;Reactome: R-HSA-5696400;Reactome: R-HSA-69601;Reactome: R-HSA-5655862;Reactome: R-HSA-3785653;Reactome: R-HSA-110312;Reactome: R-HSA-9613829;Reactome: R-HSA-2467813;Reactome: R-HSA-975957;Reactome: R-HSA-1295596;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-174048;Reactome: R-HSA-1234176;Reactome: R-HSA-2691232;Reactome: R-HSA-3769402	"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of necroptotic cell death";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Oncogene Induced Senescence";"Downregulation of ERBB4 signaling";"Regulation of TP53 Activity through Methylation";"APC-Cdc20 mediated degradation of Nek2A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Eukaryotic Translation Termination";"Modulation by Mtb of host immune system";"Dual incision in TC-NER";"ER Quality Control Compartment (ERQC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of RUNX3 expression and activity";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Hedgehog 'on' state";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"ER-Phagosome pathway";"Formation of a pool of free 40S subunits";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"SRP-dependent cotranslational protein targeting to membrane";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Negative regulation of MET activity";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN localization";"Regulation of RUNX2 expression and activity";"Alpha-protein kinase 1 signaling pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Clathrin-mediated endocytosis";"Translation initiation complex formation";"Prevention of phagosomal-lysosomal fusion";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of TP53 Degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of TP53 Activity through Phosphorylation";"Formation of TC-NER Pre-Incision Complex";"Assembly Of The HIV Virion";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cyclin D associated events in G1";"Negative regulation of MAPK pathway";"Ovarian tumor domain proteases";"Regulation of signaling by CBL";"Major pathway of rRNA processing in the nucleolus and cytosol";"Downregulation of ERBB2 signaling";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TICAM1-dependent activation of IRF3/IRF7";"Viral mRNA Translation";"Negative regulators of DDX58/IFIH1 signaling";"Stimuli-sensing channels";"Processing of DNA double-strand break ends";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"TNFR1-induced NFkappaB signaling pathway";"Degradation of AXIN";"Glycogen synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Budding and maturation of HIV virion";"activated TAK1 mediates p38 MAPK activation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Fanconi Anemia Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF-beta-TrCP mediated degradation of Emi1";"Formation of Incision Complex in GG-NER";"Peptide chain elongation";"ISG15 antiviral mechanism";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recognition of DNA damage by PCNA-containing replication complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Pink/Parkin Mediated Mitophagy";"Downregulation of ERBB2:ERBB3 signaling";"NIK-->noncanonical NF-kB signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TCF dependent signaling in response to WNT";"Downregulation of TGF-beta receptor signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Neddylation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Selenocysteine synthesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IRAK2 mediated activation of TAK1 complex";"Negative regulation of FGFR2 signaling";"Late endosomal microautophagy";"Amyloid fiber formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IRAK1 recruits IKK complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Metalloprotease DUBs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"TICAM1, RIP1-mediated IKK complex recruitment";"Peroxisomal protein import";"HDR through Homologous Recombination (HRR)";"Josephin domain DUBs";"MAPK6/MAPK4 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of innate immune responses to cytosolic DNA";"EGFR downregulation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxidative Stress Induced Senescence";"Stabilization of p53";"InlA-mediated entry of Listeria monocytogenes into host cells";"Translesion Synthesis by POLH";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ubiquitin-dependent degradation of Cyclin D";"Activated NOTCH1 Transmits Signal to the Nucleus";"Senescence-Associated Secretory Phenotype (SASP)";"Iron uptake and transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of TNFR1 signaling";"Membrane binding and targetting of GAG proteins";"Regulation of PLK1 Activity at G2/M Transition";"Negative regulation of FGFR1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"InlB-mediated entry of Listeria monocytogenes into host cell";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"DNA Damage Recognition in GG-NER";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Aggrephagy";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translesion synthesis by POLI";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Termination of translesion DNA synthesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IKK complex recruitment mediated by RIP1";"Dual Incision in GG-NER";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by POLK";"Myoclonic epilepsy of Lafora";"Translesion synthesis by REV1";"Chaperone Mediated Autophagy";"Separation of Sister Chromatids";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Spry regulation of FGF signaling";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"APC/C:Cdc20 mediated degradation of Cyclin B";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Deactivation of the beta-catenin transactivating complex"
XP_046609510.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046623491.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046610357.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046603528.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618143.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046602920.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_046619986.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046622388.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007	"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"p38MAPK events"
XP_046612942.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_046619186.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_046615883.1	15	MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7383	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_046608885.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046626357.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046607263.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046602921.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_046626118.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046624708.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_046626998.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046613662.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046615029.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046620107.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_046605326.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046611110.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_046619053.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046614741.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046608099.1	13	Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-6367;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-202433	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"FCERI mediated MAPK activation";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"Generation of second messenger molecules"
XP_046603476.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_046609693.1	19	MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Cysteine and methionine metabolism"
XP_046612824.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955	"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_046619163.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046608659.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046622151.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046605555.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046611003.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_046618309.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_046628575.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046616758.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046615024.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046627147.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046606441.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046612960.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion"
XP_046611004.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046619065.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628637.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046617816.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_046607204.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046603072.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_046612357.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-373080	"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell";"Activation of SMO";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)"
XP_046609312.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046625206.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046609963.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046612936.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_046610409.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046623347.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046606994.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_046614874.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046617761.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046621299.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046613351.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046624079.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins"
XP_046615656.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_046617645.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046608912.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046618904.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046628430.1	10	Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_046625022.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis"
XP_046607001.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_046622386.1	11	Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097	"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway"
XP_046614811.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680	"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity"
XP_046618158.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046611363.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_046624482.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_046612349.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-1234176	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_046609115.1	4	MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Spermidine biosynthesis III";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_046603396.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046604771.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046618307.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046624165.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046620933.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_046607966.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046623435.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046626794.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046604472.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_046603843.1	7	KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-7118;MetaCyc: PWY-6969;MetaCyc: PWY-7294;MetaCyc: PWY-7295	"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV";"L-arabinose degradation IV"
XP_046610910.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-1368108	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_046613157.1	11	Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237	"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2"
XP_046602852.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046621632.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616667.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046607210.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_046607862.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_046623991.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046612443.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046611147.1	8	KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6	"Pentose phosphate pathway";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_046609008.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)"
XP_046606443.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046628610.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II"
XP_046622253.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046621359.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046611378.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046617240.1	12	MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I"
XP_046609762.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046611835.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046627339.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
XP_046624713.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046607618.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_046627714.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_046619092.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046603620.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046624312.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046627636.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046613248.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046629497.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046604162.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_046622079.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046609981.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046630151.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_046609392.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046604773.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_046603542.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_046618677.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046617363.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_046609922.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_046612789.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046622008.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046612391.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_046617855.1	6	KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_046602907.1	13	Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837	"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation"
XP_046620198.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046617862.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046626920.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046613389.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046628769.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046610868.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_046626792.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046623059.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-73980;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-76066;Reactome: R-HSA-6782135	"RNA Polymerase III Chain Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"mRNA Capping";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER"
XP_046610953.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046627084.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_046615243.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046619196.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_046622117.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_046626799.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046618232.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_046628816.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046629331.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence"
XP_046625847.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046624712.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046602933.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_046602997.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046603038.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046616081.1	19	MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism"
XP_046628314.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_046615933.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_046622523.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046616150.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046623280.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046630408.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046619872.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046628741.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046616182.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046620826.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695	"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation"
XP_046622940.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046614629.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046612348.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_046604101.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046630517.1	58	Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5689901;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"G2/M Checkpoints";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of AXIN";"Metalloprotease DUBs";"ER-Phagosome pathway";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046626800.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046606492.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046623117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046604596.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046621817.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_046616844.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046607220.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046625947.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046620021.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7858;Reactome: R-HSA-9033241	"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import"
XP_046612897.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046619873.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046606220.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046618236.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046618688.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_046604851.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046616073.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-400206	"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha"
XP_046622175.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046616118.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046616986.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046611380.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_046629216.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_046626775.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046622898.1	18	KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482925	"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG"
XP_046607405.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046625340.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046613787.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046612916.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046626749.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046626624.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046611112.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_046605557.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046626588.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046628187.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046614113.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046626601.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_046613449.1	11	Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-877312	"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"Regulation of IFNG signaling"
XP_046614653.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046624860.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_046608349.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism"
XP_046614291.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_046628710.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_046617299.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046625181.1	27	Reactome: R-HSA-399956;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-8939902;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5674400;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-75815;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716	"CRMPs in Sema3A signaling";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"B-WICH complex positively regulates rRNA expression";"Regulation of RUNX2 expression and activity";"Thermogenesis";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ubiquitin-dependent degradation of Cyclin D";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_046618653.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046624240.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_046616183.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046608311.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046629214.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046623845.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_046627409.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046624521.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046603936.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_046608150.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046616674.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046617998.1	17	Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6679;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2	"Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Aflatoxin biosynthesis"
XP_046620738.1	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
XP_046614777.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046605334.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046621989.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046611742.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046623389.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_046615965.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046624284.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046609589.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046613309.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046630249.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046612659.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_046622304.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046609546.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism"
XP_046623707.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618549.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_046624276.1	39	Reactome: R-HSA-5658623;Reactome: R-HSA-5655253;Reactome: R-HSA-5654726;Reactome: R-HSA-2033514;Reactome: R-HSA-5655302;Reactome: R-HSA-2219530;Reactome: R-HSA-5654710;Reactome: R-HSA-5654704;Reactome: R-HSA-190372;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-5654695;Reactome: R-HSA-5654727;Reactome: R-HSA-5654219;Reactome: R-HSA-8853338;Reactome: R-HSA-1257604;Reactome: R-HSA-5654700;Reactome: R-HSA-109704;Reactome: R-HSA-5654706;Reactome: R-HSA-190371;Reactome: R-HSA-5654228;Reactome: R-HSA-5654227;Reactome: R-HSA-5673001;Reactome: R-HSA-5654719;Reactome: R-HSA-5654221;Reactome: R-HSA-5654699;Reactome: R-HSA-190375;Reactome: R-HSA-5654712;Reactome: R-HSA-190373;Reactome: R-HSA-5654720;Reactome: R-HSA-2033519;Reactome: R-HSA-5654693;Reactome: R-HSA-5654687;Reactome: R-HSA-1839122;Reactome: R-HSA-5654688;Reactome: R-HSA-190322;Reactome: R-HSA-6811558;Reactome: R-HSA-1839130;Reactome: R-HSA-5654689	"FGFRL1 modulation of FGFR1 signaling";"Signaling by FGFR2 in disease";"Negative regulation of FGFR1 signaling";"FGFR3 mutant receptor activation";"Signaling by FGFR1 in disease";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR3";"FGFR3c ligand binding and activation";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"PI-3K cascade:FGFR2";"Negative regulation of FGFR2 signaling";"Phospholipase C-mediated cascade: FGFR1";"Signaling by FGFR3 point mutants in cancer";"PIP3 activates AKT signaling";"FRS-mediated FGFR2 signaling";"PI3K Cascade";"FRS-mediated FGFR3 signaling";"FGFR3b ligand binding and activation";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade, FGFR3";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR4";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR2";"FGFR2c ligand binding and activation";"FRS-mediated FGFR4 signaling";"FGFR1c ligand binding and activation";"PI-3K cascade:FGFR4";"Activated point mutants of FGFR2";"FRS-mediated FGFR1 signaling";"Downstream signaling of activated FGFR1";"Signaling by activated point mutants of FGFR1";"SHC-mediated cascade:FGFR1";"FGFR4 ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by activated point mutants of FGFR3";"PI-3K cascade:FGFR1"
XP_046615054.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046611625.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046628854.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046620120.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046606916.1	11	Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_046608298.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046608021.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046620739.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI"
XP_046608260.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_046604300.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046618296.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_046621816.1	11	MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-5659;MetaCyc: PWY-3881;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8	"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_046626406.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_046610504.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046626383.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046619278.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events"
XP_046607638.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046621327.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_046613789.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046613897.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_046605553.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_046604048.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046603570.1	6	Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183	"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046606190.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046624809.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_046604886.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046621658.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046627319.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_046624474.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046603953.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_046609248.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046613263.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046603337.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046610123.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046608869.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046618173.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046616276.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046628389.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_046604729.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_046611718.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_046613136.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618084.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_046621735.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046621545.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-7822	"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)"
XP_046617670.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046629282.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046626412.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046616899.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046630392.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_046614679.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_046622078.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046616963.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046613034.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_046605632.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613503.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046611416.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046613961.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046621348.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046607660.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_046627244.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_046618567.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046609689.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046609541.1	14	MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I"
XP_046603643.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046625433.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046613956.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046626000.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046619823.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275	"Chylomicron clearance";"Clathrin-mediated endocytosis";"VLDL assembly";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Chylomicron remodeling";"VLDL clearance";"Scavenging by Class A Receptors";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"LDL clearance";"Post-translational protein phosphorylation"
XP_046623627.1	24	KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5218920;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 04151+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-9634635	"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated vascular permeability";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"Thermogenesis";"RSK activation";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"PI3K-Akt signaling pathway";"Downstream TCR signaling";"Integrin signaling";"Estrogen-stimulated signaling through PRKCZ"
XP_046622547.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046614057.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_046603935.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_046620245.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046625244.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_046610474.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046630191.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046628586.1	12	MetaCyc: PWY-5108;MetaCyc: PWY-6672;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1	"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Pyruvate metabolism";"Propanoate metabolism"
XP_046603411.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046625654.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_046623342.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_046607753.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046616845.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046628063.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046605461.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046624790.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046629335.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_046627754.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046623492.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)"
XP_046606909.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events"
XP_046626170.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046610570.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613225.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_046630379.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046628830.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-381426	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046606101.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046616987.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046610782.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695	"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation"
XP_046626411.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046618044.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046610845.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046629809.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046606250.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-174411	"Translesion synthesis by POLK";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere"
XP_046613863.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046623125.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628587.1	12	KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118	"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol"
XP_046612591.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605507.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_046608157.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_046628673.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046618828.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_046616124.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046627123.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046630536.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_046606271.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_046608664.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_046614530.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046613476.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046607399.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046630045.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046604253.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046604922.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046625690.1	8	Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665	"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_046621298.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046619647.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425	"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046619438.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622601.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046603089.1	4	Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance"
XP_046606783.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046626497.1	5	Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787	"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state"
XP_046625566.1	34	Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-69273	"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046626809.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_046605536.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex"
XP_046606498.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046615504.1	17	Reactome: R-HSA-74217;MetaCyc: PWY-4202;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-6611;MetaCyc: PWY-5695;MetaCyc: PWY-6620	"Purine salvage";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Salinosporamide A biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage"
XP_046605235.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046609214.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046614855.1	33	Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-6781823;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of TC-NER Pre-Incision Complex";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046614891.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046611365.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis"
XP_046627615.1	15	KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7003	"Purine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol"
XP_046604738.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046623463.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_046607408.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046608066.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046623485.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046625645.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046613498.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046606298.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_046609576.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046615462.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046613481.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046606520.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046623377.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_046613631.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046619852.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046628514.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046610349.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046606936.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046616661.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046627331.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_046617683.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_046612695.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation"
XP_046619445.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046622111.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624577.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046611797.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046610277.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046603901.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_046629669.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046613014.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046626576.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_046627384.1	3	Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation"
XP_046607865.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046616577.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046625563.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_046618328.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046605143.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046626453.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046625493.1	14	MetaCyc: PWY-5078;MetaCyc: PWY-5101;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5057;Reactome: R-HSA-70895;MetaCyc: PWY-5108	"L-isoleucine degradation II";"L-isoleucine biosynthesis II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-leucine degradation III";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V"
XP_046622991.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046622455.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_046609657.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_046619376.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_046627531.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046615881.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046621462.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046626600.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism"
XP_046629289.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046629907.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046610809.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_046623343.1	5	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-198323	"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol"
XP_046616257.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046621615.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6807505	"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes"
XP_046609364.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257	"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"UCH proteinases";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN"
XP_046605988.1	5	Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase"
XP_046618340.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046623520.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_046603823.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046625949.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_046622645.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046627526.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046626773.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046620929.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046612017.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_046611014.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling"
XP_046624391.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_046624613.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046625439.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046629740.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046608132.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046605946.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046620981.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046618570.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046621659.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046604665.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046614805.1	11	Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046625166.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046617242.1	12	MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_046614980.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046617436.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_046604775.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_046605626.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_046614732.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP"
XP_046605431.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG"
XP_046617756.1	11	Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_046608156.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046627254.1	12	KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4	"Sulfur metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Selenocompound metabolism"
XP_046629639.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046609412.1	31	MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-7858	"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II"
XP_046629101.1	6	MetaCyc: PWY-6367;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_046610248.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_046628467.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046626482.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046615271.1	3	Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807	"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling"
XP_046619570.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046617296.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046618004.1	17	MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168	"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Biotin transport and metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)"
XP_046605647.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046615486.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046611015.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_046604650.1	12	Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"G alpha (q) signalling events";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"DCC mediated attractive signaling";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046623337.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_046607586.1	5	Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation"
XP_046609964.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_046623243.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046608782.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046606049.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_046622131.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046604649.1	12	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"DCC mediated attractive signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046625558.1	8	Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection"
XP_046619861.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046628136.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046619778.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046620932.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_046606939.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046614543.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046613790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603902.1	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046623276.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046612810.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9609690	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events"
XP_046626526.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_046619711.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046619478.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046620658.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046603380.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046611170.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613620.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046604187.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629443.1	6	KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia"
XP_046616629.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_046620597.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046610251.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046614398.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946	"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion homeostasis";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants"
XP_046606263.1	25	Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8951936;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8939245;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8931987	"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates p14-ARF";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates estrogen receptor mediated transcription"
XP_046624460.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046607281.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006	"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_046615203.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046612828.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-114608	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation"
XP_046613331.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046603568.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_046621342.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046629510.1	13	MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_046604168.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER"
XP_046613771.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_046613221.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046607869.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046618612.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046613465.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046609704.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046611960.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046616968.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046618601.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046622152.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046613366.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_046604651.1	12	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling"
XP_046630532.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046617672.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046629720.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_046606819.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_046630487.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046617639.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046616156.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046624076.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046615691.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046610371.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046613244.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046613336.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046612690.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046625568.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"LDL clearance";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class A Receptors";"VLDL clearance";"Chylomicron remodeling";"Scavenging by Class B Receptors"
XP_046621662.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_046623273.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046620808.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046613247.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046628149.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046611907.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046617872.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046614157.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046629665.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046629050.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046616997.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_046626102.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046622637.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046611132.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046613199.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_046608993.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046628282.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046624101.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046612986.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878	"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport"
XP_046617156.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_046606528.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046616554.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_046622696.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_046621332.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046615070.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627065.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-381038	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes"
XP_046608309.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046607954.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628512.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046616782.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_046614321.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants"
XP_046610709.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046606303.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910	"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs"
XP_046612311.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046627950.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_046603063.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_046626695.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046612319.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046611033.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_046622706.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_046628499.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046619435.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046614635.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046606111.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_046621319.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046616353.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_046628403.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-432142	"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL"
XP_046605207.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046620207.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046619195.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046626278.1	5	KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation"
XP_046619436.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046614064.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046604530.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046623180.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_046627001.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046611059.1	7	KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis"
XP_046612100.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046615981.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046623714.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046603045.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046626599.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046607302.1	13	Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204	"DAP12 signaling";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
XP_046612479.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_046607094.1	2	Reactome: R-HSA-5656169;Reactome: R-HSA-9033241	"Termination of translesion DNA synthesis";"Peroxisomal protein import"
XP_046627804.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_046618644.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046616290.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_046614783.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046615850.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046607866.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046619505.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046613124.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_046621465.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046603032.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046622716.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046616165.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046608224.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046618616.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046611549.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046622380.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619844.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_046625644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614934.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046609715.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046607792.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046621898.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046620987.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_046623338.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046630100.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046620014.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7288	"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_046623900.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046626540.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_046604590.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046614632.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046610561.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046606776.1	6	KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_046604510.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_046607606.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence"
XP_046615291.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_046604731.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046609928.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046615349.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046612558.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622719.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046614305.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046628453.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046625874.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046615341.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation"
XP_046622103.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046607601.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884	"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX"
XP_046616363.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046620322.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_046606255.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046621873.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046622232.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046625437.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046610982.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046609691.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046606746.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_046607016.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046617038.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046617605.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046623930.1	9	Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_046625330.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046615696.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_046611616.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_046617545.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046621734.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046609968.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_046628251.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_046613450.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-114604	"Regulation of IFNA signaling";"PD-1 signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"GPVI-mediated activation cascade"
XP_046606451.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_046607941.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046612277.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046605011.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046625545.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046623573.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_046622452.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046618983.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046605753.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046607882.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046614348.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046629648.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046625997.1	4	MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_046611263.1	19	MetaCyc: PWY-7184;MetaCyc: PWY-7221;Reactome: R-HSA-380320;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;Reactome: R-HSA-380270;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7176	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"CMP phosphorylation";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis"
XP_046629567.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046620951.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046626726.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-9013508	"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_046613862.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046616166.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046628566.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046622748.1	27	Reactome: R-HSA-72086;Reactome: R-HSA-73856;Reactome: R-HSA-159227;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-159236;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-6803529;Reactome: R-HSA-77588;Reactome: R-HSA-159231;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-167152;Reactome: R-HSA-975956;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-77595;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-113418	"mRNA Capping";"RNA Polymerase II Transcription Termination";"Transport of the SLBP independent Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"FGFR2 alternative splicing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Formation of HIV elongation complex in the absence of HIV Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Processing of Intronless Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"Formation of the Early Elongation Complex"
XP_046616517.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046624239.1	12	MetaCyc: PWY-6978;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5870	"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_046609394.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618001.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765	"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression"
XP_046621987.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046618950.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046620070.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046612875.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion"
XP_046626623.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046622623.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046603395.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046621346.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046628280.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046614294.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_046613639.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046617637.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046625849.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046619847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606018.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_046614414.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324	"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_046626621.1	3	Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893	"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase"
XP_046604271.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046624806.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_046610881.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_046618009.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046615701.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046610617.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC"
XP_046618957.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046627327.1	7	Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661	"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_046612438.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046613372.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046625559.1	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046616247.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046622900.1	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_046617843.1	7	Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"HATs acetylate histones";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex"
XP_046612266.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046625744.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_046608881.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046628611.1	4	MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_046629395.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046627429.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046606100.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_046610416.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046630194.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046621541.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_046612533.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_046622260.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046629667.1	2	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions"
XP_046629119.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046617394.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046610851.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046615293.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_046615669.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046613316.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+"
XP_046605400.1	11	Reactome: R-HSA-8943724;Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-8862803;Reactome: R-HSA-2559582;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580	"Regulation of PTEN gene transcription";"MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence"
XP_046628031.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046618275.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046621445.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_046619185.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_046603499.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046623659.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046603393.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046623484.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046614309.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046612188.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046628634.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046620729.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-174411	"Translesion synthesis by POLK";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere"
XP_046610661.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046604317.1	6	Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-452723;Reactome: R-HSA-6785807;Reactome: R-HSA-2892245;Reactome: R-HSA-3769402	"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Deactivation of the beta-catenin transactivating complex"
XP_046617458.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046630370.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046619940.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046611956.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046620334.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046614292.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-438066	"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion homeostasis";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_046630195.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046622552.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046619236.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046607420.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046619550.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046604302.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046622268.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046618134.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_046618175.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046604328.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_046618869.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046616055.1	2	KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046619856.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK"
XP_046611417.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046608074.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046627485.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_046618742.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046618400.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_046611151.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046613630.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046615269.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046620714.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_046615292.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_046617536.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_046603906.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_046607752.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046610099.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046614979.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046603469.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046616870.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate"
XP_046613907.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046628903.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046619359.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046604763.1	18	KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046623244.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046619123.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046628832.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046623091.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046611501.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046610756.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046614809.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046627456.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046622524.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046613953.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046622829.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_046610141.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046616673.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046609235.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046629439.1	6	Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12	"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_046622792.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_046629783.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_046613223.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046616980.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046608930.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_046623990.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603373.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_046613355.1	7	MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_046624238.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5873	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_046615121.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046613959.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_046604804.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046603625.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046610455.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046625241.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_046626717.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046621597.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046613213.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_046626735.1	5	MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_046630374.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046625915.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046607854.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046612281.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046619345.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606941.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859	"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly"
XP_046622104.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649	"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation"
XP_046612400.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046610380.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_046605328.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046626932.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046629221.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_046623580.1	8	KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
XP_046618773.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829	"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy"
XP_046609511.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046630046.1	14	MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1	"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism"
XP_046621004.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_046628531.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046628557.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046616490.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046609154.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_046616475.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046622794.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7606	"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_046606833.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046629363.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046619374.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_046615665.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046615372.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046612429.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046621791.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046605230.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618159.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046612910.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025	"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation"
XP_046606180.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_046603854.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046622443.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046626521.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046614948.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37	"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_046616977.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046605193.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075	"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_046608327.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046609265.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-2821;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7	"Glucosinolate biosynthesis from homomethionine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism"
XP_046609061.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_046610877.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046619108.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046624226.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211	"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"ESR-mediated signaling"
XP_046610124.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046612901.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_046623656.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046619434.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046628202.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046607578.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046607744.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046604595.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes"
XP_046622361.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046621444.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046615517.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046623818.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046622767.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1"
XP_046622772.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_046625740.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046614314.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_046605449.1	9	Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68827	"Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex"
XP_046619997.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046620342.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046609057.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_046613072.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy"
XP_046620208.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046614850.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046617615.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_046616848.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_046603805.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046604163.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046620698.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_046630367.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046604664.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046610603.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC"
XP_046605726.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622482.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046616838.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046626172.1	3	Reactome: R-HSA-168928;Reactome: R-HSA-9639288;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amino acids regulate mTORC1";"Fructose catabolism"
XP_046607867.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046623424.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046609538.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046617379.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046626795.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_046629403.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_046625266.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111469	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response"
XP_046617633.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046604531.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046611545.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046617391.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046625474.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046619112.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_046621029.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_046618335.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046615577.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins"
XP_046617016.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_046616338.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_046611162.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_046619263.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046606917.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Purine metabolism";"PKA activation"
XP_046612185.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_046628062.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046609048.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046628488.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_046607386.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_046625084.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade"
XP_046627556.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046623582.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046623846.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408	"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation"
XP_046625363.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046611531.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046620725.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_046612766.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-171306	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis";"Cleavage of the damaged purine";"Packaging Of Telomere Ends"
XP_046627047.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629604.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046608262.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_046628465.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607628.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046608796.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046605994.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_046606450.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_046620165.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_046614097.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_046606026.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695	"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Neutrophil degranulation"
XP_046604204.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046621294.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046626719.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_046616267.1	17	MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"CMP phosphorylation"
XP_046606711.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046626702.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046612041.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046605952.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046605231.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046613573.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_046610602.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_046603136.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_046606908.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046618866.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Recycling pathway of L1";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046619097.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622167.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046621543.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation"
XP_046626115.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046623815.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046609321.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046619741.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607252.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6"
XP_046606207.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046622395.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046624160.1	5	Reactome: R-HSA-4755579;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046614808.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_046610346.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046613353.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046613356.1	7	MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191	"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PC"
XP_046629903.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046623341.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_046611879.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046615090.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046602913.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_046615057.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046608184.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046615275.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046607886.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_046604567.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046602981.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_046617999.1	17	Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744	"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Glyoxylate assimilation"
XP_046613371.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_046616275.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046605170.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans"
XP_046621617.1	9	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167287	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery"
XP_046622795.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import"
XP_046611931.1	6	KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807	"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_046619122.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046615086.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_046625347.1	6	MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395	"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_046609387.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_046630393.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-2151201	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis"
XP_046620380.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046609114.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_046626142.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_046605442.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046606984.1	10	KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis"
XP_046623807.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046611236.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046603838.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046624836.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046615294.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_046606781.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-111465	"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins"
XP_046606709.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination"
XP_046622135.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046617568.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046606065.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046623725.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_046617634.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_046609046.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_046618407.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046616679.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046612071.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046620944.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046603979.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046609767.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_046619062.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046612244.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046606700.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_046616801.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046627854.1	4	KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_046625179.1	27	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610783;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;KEGG: 04151+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5467337;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-399956;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5674400;Reactome: R-HSA-75815;Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340	"Human immunodeficiency virus 1 infection";"Degradation of GLI2 by the proteasome";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI3K-Akt signaling pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"APC truncation mutants have impaired AXIN binding";"Human cytomegalovirus infection";"B-WICH complex positively regulates rRNA expression";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"Regulation of RUNX2 expression and activity";"CRMPs in Sema3A signaling";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"Ubiquitin-dependent degradation of Cyclin D";"Beta-catenin phosphorylation cascade";"Thermogenesis";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex"
XP_046628580.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_046626478.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046613583.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy"
XP_046610754.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046621349.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046618871.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046607554.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046608109.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046618486.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046616078.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300	"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors"
XP_046624476.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_046606072.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046611969.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046616000.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis"
XP_046624906.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046615354.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736	"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors"
XP_046605782.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_046606541.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046612559.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046608611.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046607331.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_046629668.1	4	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Glycerol degradation I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_046611339.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046612387.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046614628.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046609724.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046613315.1	6	Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events"
XP_046610576.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046608723.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_046618205.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046614573.1	42	Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-8936459;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-427413;Reactome: R-HSA-73728;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-5625886;Reactome: R-HSA-171306;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-912446	"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"RMTs methylate histone arginines";"DNA methylation";"HATs acetylate histones";"HDACs deacetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"Estrogen-dependent gene expression";"HCMV Early Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Packaging Of Telomere Ends";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination"
XP_046609694.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046615073.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046615676.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046607794.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046619966.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046622647.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046621249.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_046603726.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046615770.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615591.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046625217.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046603825.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046609342.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046618991.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046616502.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046623106.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046623344.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046616494.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854	"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_046606522.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046615162.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046624858.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046618342.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046608171.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046629483.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046609672.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_046609859.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046621142.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_046622272.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389	"Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases"
XP_046609732.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046609420.1	31	MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;Reactome: R-HSA-75105	"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis"
XP_046613174.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046624100.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046623391.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_046618990.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046604469.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046614951.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046608925.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_046628055.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046615520.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046621869.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport"
XP_046612156.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_046613474.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_046626628.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046613668.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046620922.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046607282.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_046615078.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046630070.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046628715.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_046616613.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion"
XP_046624623.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046614523.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046611047.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_046610753.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_046628487.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_046629452.1	9	Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-416476	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"G alpha (q) signalling events"
XP_046618907.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046610615.1	14	KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_046619245.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046615479.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046624804.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046609058.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_046614440.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_046614349.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046627535.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046617013.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046618148.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046614930.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7574	"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II"
XP_046603569.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516	"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane"
XP_046620986.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_046619944.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046611765.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_046624528.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_046624534.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046627188.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046619965.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046608111.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046603470.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046615791.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046626343.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046620518.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_046605526.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046630343.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630441.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_046628906.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046613770.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046608516.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046628193.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628	"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_046604895.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_046606527.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046606302.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168271	"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_046607073.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046610244.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760	"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation"
XP_046616121.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046620604.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046615384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046623830.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_046612172.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046613647.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046620869.1	6	Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25	"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_046622513.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046611766.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_046607081.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046612192.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_046603046.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046623114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046623190.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_046623847.1	15	Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398	"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Ca2+ pathway"
XP_046605884.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046629285.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046609757.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046620727.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046604372.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046620197.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046606679.1	7	KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_046614221.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_046610606.1	14	MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_046614596.1	19	Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-5368286;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Mitochondrial translation initiation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046618664.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046612428.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046609062.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046620704.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_046621324.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046629517.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046610122.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046612686.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605281.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_046604841.1	8	KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;MetaCyc: PWY-8086	"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_046613655.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046626039.1	17	MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7184	"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_046623357.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046606713.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046612390.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_046614341.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001	"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade"
XP_046608039.1	7	Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158	"Phenylalanine metabolism";"Phenylketonuria";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V"
XP_046617931.1	10	Reactome: R-HSA-3214847;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1	"HATs acetylate histones";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Ub-specific processing proteases";"Thermogenesis"
XP_046614130.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046625691.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-432720	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Lysosome Vesicle Biogenesis"
XP_046604445.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046616387.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_046612890.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport"
XP_046619643.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046610596.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-1632852;Reactome: R-HSA-68877;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Macroautophagy";"Mitotic Prometaphase";"Aggrephagy"
XP_046605637.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046613485.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046613250.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046607356.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046607743.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046607702.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046607018.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_046607378.1	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046625746.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046610879.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation"
XP_046625176.1	27	Reactome: R-HSA-8939902;Reactome: R-HSA-5250924;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-399956;Reactome: R-HSA-75815;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5674400;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358751;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-5610783;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 04151+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-3371453	"Regulation of RUNX2 expression and activity";"B-WICH complex positively regulates rRNA expression";"Relaxin signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"CRMPs in Sema3A signaling";"Ubiquitin-dependent degradation of Cyclin D";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Thermogenesis";"S45 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex";"Degradation of GLI2 by the proteasome";"mTOR signaling pathway";"APC truncation mutants have impaired AXIN binding";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI3K-Akt signaling pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of HSF1-mediated heat shock response"
XP_046624497.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046616501.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3301854	"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
XP_046614820.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046609701.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046621316.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046614235.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046623345.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046607216.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_046612728.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046621544.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_046622382.1	11	KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302	"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"p38MAPK events";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation"
XP_046630454.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046620798.1	3	Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664	"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation"
XP_046604102.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046604717.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046629810.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627719.1	33	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_046613173.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046608117.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_046620726.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_046627458.1	6	Reactome: R-HSA-1483166;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;MetaCyc: PWY-5668	"Synthesis of PA";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Cardiolipin biosynthesis I"
XP_046629849.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046615044.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046617995.1	17	KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599	"Pyruvate metabolism";"Glyoxylate assimilation";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency"
XP_046621463.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046624518.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046619009.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046622644.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046629811.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046626574.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046621276.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_046606189.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_046608475.1	8	KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581	"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis I"
XP_046620683.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis"
XP_046628166.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-9020702	"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling"
XP_046629287.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046611068.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis"
XP_046614342.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046622043.1	7	MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8	"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_046625331.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_046611729.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046626634.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046622381.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580	"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence"
XP_046605951.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046628564.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046614912.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046623067.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_046616468.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046616503.1	7	MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-5578999	"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_046606987.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)"
XP_046626523.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046607218.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_046628508.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_046613052.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110357;Reactome: R-HSA-110373	"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_046628404.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-4641262	"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046627000.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046628698.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046612880.1	9	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors"
XP_046606218.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046611997.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046610403.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046611289.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_046628141.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_046628570.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046608067.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046607299.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046610373.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_046628696.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046626927.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046604326.1	3	KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3	"Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism"
XP_046621373.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_046621008.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_046627191.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046605423.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_046624487.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046626108.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046621836.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2	"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism"
XP_046621931.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_046624853.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046619638.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046615664.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046620737.1	4	Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_046604479.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046610640.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046610053.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046624913.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046626622.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046619527.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046602905.1	13	Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5607764	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling"
XP_046623764.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046602969.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046604109.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000	"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"RAF activation"
XP_046609489.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046623120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628026.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046621290.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-933541;Reactome: R-HSA-936440	"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling"
XP_046623986.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046607407.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046616104.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046624624.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_046615542.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046607914.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046622682.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046611513.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_046615652.1	12	KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;MetaCyc: PWY-7343;Reactome: R-HSA-173599;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycerolipid metabolism";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II"
XP_046604501.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046619093.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046618430.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046613962.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046620728.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046613827.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_046606810.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046626166.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046604466.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_046623064.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046608083.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613140.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046620804.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046622384.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection"
XP_046628007.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046604324.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046610686.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046626713.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex"
XP_046619788.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins"
XP_046626781.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046607085.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046624791.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046618891.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046614918.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046623355.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_046611356.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046604800.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046607208.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_046625469.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-2132295	"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"LDL clearance";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation"
XP_046613769.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046610663.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046607467.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_046628184.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046605690.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_046619317.1	7	KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_046624179.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046609544.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046623408.1	5	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_046607268.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046622599.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_046626538.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_046620918.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046626195.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046611362.1	6	Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36	"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
XP_046614920.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046616820.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046618721.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046618602.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_046618146.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046622369.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615852.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046629789.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_046618049.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046620136.1	8	MetaCyc: PWY-6611;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217	"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Neutrophil degranulation";"Purine salvage"
XP_046614889.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_046607300.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046603379.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046619937.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046617202.1	6	Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_046625105.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046617830.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046607357.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046617390.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046614636.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046618002.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722	"3-hydroxypropanoate cycle";"Carnitine metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Candicidin biosynthesis"
XP_046624591.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_046626543.1	6	KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046610454.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046612768.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_046612597.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046603012.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046624551.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046627606.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046627533.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046623119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046607083.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046630155.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046608134.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046608189.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046621026.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_046604802.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046606258.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046620389.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046611558.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275	"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation"
XP_046619492.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046609370.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_046616655.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046626798.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046623392.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_046603511.1	5	KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-5523;MetaCyc: PWY-7863	"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis"
XP_046613530.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046604903.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046613239.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046604003.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-432720	"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis"
XP_046628667.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046623821.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046615258.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_046605528.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046605504.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_046604169.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_046629028.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046605004.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046615543.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046626088.1	11	Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599	"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases"
XP_046622514.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046611864.1	44	Reactome: R-HSA-1295596;Reactome: R-HSA-112409;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-450341;Reactome: R-HSA-2029482;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-2559580;Reactome: R-HSA-5674499;Reactome: R-HSA-162658;Reactome: R-HSA-445144;Reactome: R-HSA-982772;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-8940973;Reactome: R-HSA-198753;Reactome: R-HSA-5654732;Reactome: R-HSA-5663213;Reactome: R-HSA-8943724;Reactome: R-HSA-5654733;Reactome: R-HSA-202670;Reactome: R-HSA-5654727;Reactome: R-HSA-5668599;Reactome: R-HSA-9634638;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-879415;Reactome: R-HSA-5674135;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-456926;Reactome: R-HSA-3371453;Reactome: R-HSA-9635465;Reactome: R-HSA-5654726;Reactome: R-HSA-444257;Reactome: R-HSA-9627069;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5675221;Reactome: R-HSA-2559585;Reactome: R-HSA-6802946	"Spry regulation of FGF signaling";"RAF-independent MAPK1/3 activation";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Activation of the AP-1 family of transcription factors";"Regulation of actin dynamics for phagocytic cup formation";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Oxidative Stress Induced Senescence";"Negative feedback regulation of MAPK pathway";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signal transduction by L1";"Growth hormone receptor signaling";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"RUNX2 regulates osteoblast differentiation";"ERK/MAPK targets";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of PTEN gene transcription";"Negative regulation of FGFR4 signaling";"ERKs are inactivated";"Negative regulation of FGFR2 signaling";"RHO GTPases Activate NADPH Oxidases";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"Advanced glycosylation endproduct receptor signaling";"MAP2K and MAPK activation";"FCERI mediated MAPK activation";"Signal attenuation";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of HSF1-mediated heat shock response";"Suppression of apoptosis";"Negative regulation of FGFR1 signaling";"RSK activation";"Regulation of the apoptosome activity";"mTOR signaling pathway";"Negative regulation of MAPK pathway";"Oncogene Induced Senescence";"Signaling by moderate kinase activity BRAF mutants"
XP_046604159.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046606735.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046617621.1	9	Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5743	"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle"
XP_046617257.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485	"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis"
XP_046603885.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046610641.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_046608924.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_046606531.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046609052.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_046611171.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046627911.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046629194.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_046617949.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_046604186.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046608920.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046618906.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046616567.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046616426.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_046612506.1	5	Reactome: R-HSA-71336;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4	"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway"
XP_046627414.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046619825.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046622517.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046620079.1	17	Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"Meiotic synapsis";"Processing of DNA double-strand break ends";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_046629568.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046609810.1	5	MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-3781	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)"
XP_046615710.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_046622853.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046630224.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling"
XP_046618377.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_046614256.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_046608653.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_046627393.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046614310.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046622076.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_046628135.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_046604496.1	8	Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis"
XP_046614356.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism"
XP_046621509.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046615427.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606636.1	8	Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046624394.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046624059.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_046626871.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046616872.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_046630439.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_046627726.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749	"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs"
XP_046609158.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-72086	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping"
XP_046611476.1	10	Reactome: R-HSA-913709;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;MetaCyc: PWY-7661	"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein N-glycosylation (Haloferax volcanii)"
XP_046626822.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046620811.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046612336.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_046615889.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046609660.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids"
XP_046628429.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;MetaCyc: PWY-6397	"Galactose catabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_046629957.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046604796.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046616978.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046608068.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_046627261.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046628704.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046624431.1	6	Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_046614369.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046613020.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_046604726.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046615259.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_046603637.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046630250.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046624667.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614594.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52	"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis"
XP_046629438.1	6	Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12	"Defective GALT can cause Galactosemia";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_046613551.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046630561.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046605351.1	3	Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism"
XP_046605896.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046613610.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
XP_046625169.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046629479.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046611212.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046611775.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618174.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_046612975.1	7	KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4	"Butanoate metabolism";"Mevalonate degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Valine, leucine and isoleucine degradation"
XP_046614088.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_046615482.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046607960.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle"
XP_046611602.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_046622598.1	12	Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5856	"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_046606497.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046625516.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046618280.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA"
XP_046626936.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046621308.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_046624498.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046624854.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046628150.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046604064.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046621366.1	10	Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6372;MetaCyc: PWY-6362	"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_046627577.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046608884.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046619356.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046613176.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_046613625.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046604099.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046611820.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_046613298.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046612254.1	4	KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241	"Propanoate metabolism";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import"
XP_046628127.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046625401.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_046610865.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046629392.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046623861.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046604801.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046616484.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Protein ubiquitination"
XP_046629257.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046604511.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046621786.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046624036.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609133.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046628456.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046606122.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046619094.1	4	Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14	"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism"
XP_046624350.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_046610230.1	179	Reactome: R-HSA-3785653;Reactome: R-HSA-5655862;Reactome: R-HSA-69601;Reactome: R-HSA-5696400;Reactome: R-HSA-450321;Reactome: R-HSA-937041;Reactome: R-HSA-5656169;Reactome: R-HSA-532668;Reactome: R-HSA-5656121;Reactome: R-HSA-975956;Reactome: R-HSA-4641263;Reactome: R-HSA-3769402;Reactome: R-HSA-1234176;Reactome: R-HSA-2691232;Reactome: R-HSA-174048;Reactome: R-HSA-209543;Reactome: R-HSA-1295596;Reactome: R-HSA-209560;Reactome: R-HSA-975957;Reactome: R-HSA-2467813;Reactome: R-HSA-9613829;Reactome: R-HSA-110312;Reactome: R-HSA-174084;Reactome: R-HSA-8875360;Reactome: R-HSA-5654726;Reactome: R-HSA-2565942;Reactome: R-HSA-174490;Reactome: R-HSA-5357905;Reactome: R-HSA-174154;Reactome: R-HSA-6781827;Reactome: R-HSA-9646399;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5696394;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-3134975;Reactome: R-HSA-5687128;Reactome: R-HSA-2173795;Reactome: R-HSA-5689877;Reactome: R-HSA-5685942;Reactome: R-HSA-168927;Reactome: R-HSA-9033241;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5689901;Reactome: R-HSA-68827;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-2559582;Reactome: R-HSA-75815;Reactome: R-HSA-9014325;Reactome: R-HSA-110320;Reactome: R-HSA-69541;Reactome: R-HSA-8876493;Reactome: R-HSA-2894862;Reactome: R-HSA-2559580;Reactome: R-HSA-182971;Reactome: R-HSA-936964;Reactome: R-HSA-195253;Reactome: R-HSA-2408557;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-2173791;Reactome: R-HSA-8854050;Reactome: R-HSA-975163;Reactome: R-HSA-975110;Reactome: R-HSA-8951664;Reactome: R-HSA-2173788;Reactome: R-HSA-201681;Reactome: R-HSA-1236382;Reactome: R-HSA-5696397;Reactome: R-HSA-5362768;Reactome: R-HSA-1358803;Reactome: R-HSA-9013507;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-445989;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-937039;Reactome: R-HSA-450408;Reactome: R-HSA-977225;Reactome: R-HSA-9615710;Reactome: R-HSA-5654727;Reactome: R-HSA-937042;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-156902;Reactome: R-HSA-5696395;Reactome: R-HSA-2122947;Reactome: R-HSA-6783310;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-450302;Reactome: R-HSA-162588;Reactome: R-HSA-3322077;Reactome: R-HSA-5357956;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-110314;Reactome: R-HSA-9633012;Reactome: R-HSA-9604323;Reactome: R-HSA-6782210;Reactome: R-HSA-9010553;Reactome: R-HSA-8866654;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-1169408;Reactome: R-HSA-6791226;Reactome: R-HSA-912631;Reactome: R-HSA-5689896;Reactome: R-HSA-5675221;Reactome: R-HSA-69231;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-175474;Reactome: R-HSA-156827;Reactome: R-HSA-2173796;Reactome: R-HSA-6781823;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-2672351;Reactome: R-HSA-936440;Reactome: R-HSA-192823;Reactome: R-HSA-9013973;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-8863795;Reactome: R-HSA-8948747;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-6807004;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-1799339;Reactome: R-HSA-8856825;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-72689;Reactome: R-HSA-6804757;Reactome: R-HSA-8849469;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-8866652;Reactome: R-HSA-187577;Reactome: R-HSA-9645460;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-179409;Reactome: R-HSA-6804760;Reactome: R-HSA-1253288;Reactome: R-HSA-180534;Reactome: R-HSA-2559585;Reactome: R-HSA-4608870;Reactome: R-HSA-5675482;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-5684264;Reactome: R-HSA-5632684;Reactome: R-HSA-168928;Reactome: R-HSA-8941858;Reactome: R-HSA-72706;Reactome: R-HSA-901032;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-72764	"Myoclonic epilepsy of Lafora";"Translesion synthesis by POLK";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dual Incision in GG-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IKK complex recruitment mediated by RIP1";"Termination of translesion DNA synthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion synthesis by POLI";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"Deactivation of the beta-catenin transactivating complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"APC/C:Cdc20 mediated degradation of Cyclin B";"p75NTR recruits signalling complexes";"Spry regulation of FGF signaling";"NF-kB is activated and signals survival";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Separation of Sister Chromatids";"Chaperone Mediated Autophagy";"Translesion synthesis by REV1";"Autodegradation of Cdh1 by Cdh1:APC/C";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of FGFR1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Membrane binding and targetting of GAG proteins";"Regulation of TNFR1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Aggrephagy";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"DNA Damage Recognition in GG-NER";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of innate immune responses to cytosolic DNA";"MAPK6/MAPK4 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Josephin domain DUBs";"HDR through Homologous Recombination (HRR)";"TICAM1, RIP1-mediated IKK complex recruitment";"Peroxisomal protein import";"G2/M Checkpoints";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Metalloprotease DUBs";"CDT1 association with the CDC6:ORC:origin complex";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"Senescence-Associated Secretory Phenotype (SASP)";"Ubiquitin-dependent degradation of Cyclin D";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion Synthesis by POLH";"Stabilization of p53";"InlA-mediated entry of Listeria monocytogenes into host cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxidative Stress Induced Senescence";"EGFR downregulation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Degradation of beta-catenin by the destruction complex";"Selenocysteine synthesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Neddylation";"Downregulation of TGF-beta receptor signaling";"TCF dependent signaling in response to WNT";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2:ERBB3 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK1 recruits IKK complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Amyloid fiber formation";"Late endosomal microautophagy";"Negative regulation of FGFR2 signaling";"IRAK2 mediated activation of TAK1 complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Peptide chain elongation";"Formation of Incision Complex in GG-NER";"NOTCH1 Intracellular Domain Regulates Transcription";"Fanconi Anemia Pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"activated TAK1 mediates p38 MAPK activation";"Budding and maturation of HIV virion";"Glycogen synthesis";"TNFR1-induced NFkappaB signaling pathway";"Degradation of AXIN";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Recognition of DNA damage by PCNA-containing replication complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Negative regulation of NOTCH4 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of expression of SLITs and ROBOs";"E3 ubiquitin ligases ubiquitinate target proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"ISG15 antiviral mechanism";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of signaling by CBL";"Ovarian tumor domain proteases";"Negative regulation of MAPK pathway";"Cyclin D associated events in G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Assembly Of The HIV Virion";"L13a-mediated translational silencing of Ceruloplasmin expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Stimuli-sensing channels";"Negative regulators of DDX58/IFIH1 signaling";"Viral mRNA Translation";"TICAM1-dependent activation of IRF3/IRF7";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downregulation of ERBB2 signaling";"Regulation of PTEN localization";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Negative regulation of MET activity";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"SRP-dependent cotranslational protein targeting to membrane";"Cargo recognition for clathrin-mediated endocytosis";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Formation of a pool of free 40S subunits";"Regulation of TP53 Degradation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SCF(Skp2)-mediated degradation of p27/p21";"Alpha-protein kinase 1 signaling pathway";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Activity through Methylation";"Downregulation of ERBB4 signaling";"Vpu mediated degradation of CD4";"Oncogene Induced Senescence";"Asymmetric localization of PCP proteins";"Regulation of necroptotic cell death";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Hedgehog 'on' state";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of RUNX3 expression and activity";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ER Quality Control Compartment (ERQC)";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Eukaryotic Translation Termination"
XP_046622120.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046604547.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046605805.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046611757.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046614033.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612263.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_046614568.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046606763.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-4641262	"Apoptotic cleavage of cellular proteins";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046613665.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046627237.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_046619943.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046627778.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046617849.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_046624283.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046606590.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046605596.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046610989.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery"
XP_046618381.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046625282.1	6	KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_046620260.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_046610616.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_046630332.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613871.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_046613104.1	22	MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7035;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7726	"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_046615303.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046614911.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046615879.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_046609758.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046625021.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_046624378.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046623754.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531	"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus"
XP_046606204.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_046610875.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046615982.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046611516.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695	"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation"
XP_046622277.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_046610503.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046608341.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046628424.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_046610778.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046603142.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_046622447.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_046611684.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway"
XP_046616252.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_046613257.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046612691.1	18	KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086	"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_046609213.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_046624130.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046617031.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046623546.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_046615519.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046609659.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_046621968.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_046621274.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_046618894.1	14	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-141444	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046623935.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046614660.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046616282.1	7	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II"
XP_046621737.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046627561.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046608031.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046618645.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_046607809.1	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_046608661.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046608857.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046611135.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046612669.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046616982.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046624108.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046603336.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_046607839.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046606001.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618301.1	8	Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"ATP biosynthesis";"Photosynthesis";"Ion channel transport";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_046607636.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046612797.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_046620825.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046604767.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046608671.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046619439.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046624379.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046620481.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_046626720.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2197563;Reactome: R-HSA-210744	"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_046618276.1	4	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_046613332.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046605366.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046616370.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862	"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_046619892.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046629744.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046613499.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046630121.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046626503.1	3	MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_046616357.1	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_046610622.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046611542.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046614785.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046614111.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_046609134.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046622654.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046618117.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_046620809.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046617749.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046613222.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046612823.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802948	"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants"
XP_046610187.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046611121.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046623628.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5625740;Reactome: R-HSA-114604;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-5607764;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1	"Downstream TCR signaling";"Integrin signaling";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"RSK activation";"Thermogenesis";"Regulation of TP53 Degradation";"RHO GTPases activate PKNs";"GPVI-mediated activation cascade";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CLEC7A (Dectin-1) signaling";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway"
XP_046605855.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_046618654.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612455.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-201681	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"WNT mediated activation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT"
XP_046622631.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046621790.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046623001.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_046616014.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_046622040.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_046618669.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046630340.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046603650.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046623250.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046627003.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046623065.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046618571.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046607981.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046613236.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046625338.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046617896.1	18	Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70895;Reactome: R-HSA-204174;Reactome: R-HSA-70268;MetaCyc: PWY-5084;Reactome: R-HSA-6783984;KEGG: 00640+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00310+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4	"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine degradation";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism"
XP_046621218.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189	"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046626931.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046612456.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262	"TCF dependent signaling in response to WNT";"PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046613433.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046619174.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618403.1	12	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes"
XP_046619113.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046610601.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_046607868.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613262.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046618615.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046621507.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046624891.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046617751.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046613519.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046604096.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_046603619.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046626725.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_046624114.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046610208.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)"
XP_046630078.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046626734.1	5	MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_046623256.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_046607365.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046604762.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046608426.1	13	KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation"
XP_046626570.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046612588.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046619637.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046618432.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046612732.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_046608017.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046615940.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046618433.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046620707.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046605169.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_046623088.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046609485.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046627444.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046623469.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046625406.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046615318.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046620206.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046610713.1	8	MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ATP biosynthesis";"Photosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046605201.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046622128.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046616101.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046604320.1	6	Reactome: R-HSA-2892247;Reactome: R-HSA-8986944;Reactome: R-HSA-6785807;Reactome: R-HSA-452723;Reactome: R-HSA-2892245;Reactome: R-HSA-3769402	"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Transcriptional Regulation by MECP2";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of pluripotent stem cells";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Deactivation of the beta-catenin transactivating complex"
XP_046625300.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_046606604.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607614.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594	"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events"
XP_046615604.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046617495.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_046627004.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046622717.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612974.1	7	KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074	"Valine, leucine and isoleucine degradation";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Geraniol degradation";"Butanoate metabolism";"Mevalonate degradation"
XP_046613661.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046605100.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628882.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046629693.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_046613571.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_046626403.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046607019.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046627213.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol"
XP_046614266.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046627611.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046607168.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046629562.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046611744.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046609255.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046625980.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_046620254.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614958.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5392	"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II"
XP_046607114.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046613240.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046620427.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_046628736.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046604539.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_046612619.1	10	MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_046619815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629820.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5620922	"Hedgehog 'off' state";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium"
XP_046605872.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_046607402.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046614322.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046612253.1	4	KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;Reactome: R-HSA-9033241	"Propanoate metabolism";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import"
XP_046623959.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608572.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046620200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046612101.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046615979.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046617401.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046605949.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046604093.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_046612475.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622439.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046604405.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046620952.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_046619373.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_046624857.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_046604853.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046605531.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046614316.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_046613968.1	19	Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-182971	"MAPK6/MAPK4 signaling";"Myogenesis";"DCC mediated attractive signaling";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"EGFR downregulation"
XP_046621840.1	10	MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041	"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle"
XP_046626456.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_046620256.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046613672.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046607841.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-4381;Reactome: R-HSA-75105;Reactome: R-HSA-199220	"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_046606734.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046625295.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046606413.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046610685.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_046626815.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_046623027.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_046618896.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_046628545.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046610401.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046603339.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_046616873.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_046609805.1	10	MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15	"Anandamide biosynthesis II";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism"
XP_046622429.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046624093.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046613311.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_046604216.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046614776.1	6	MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-4381	"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_046603206.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_046626541.1	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046613177.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046606183.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167287	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery"
XP_046606279.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046612613.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_046627320.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-113501	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_046603830.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622549.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046614337.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-2151209	"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Carnitine metabolism";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_046614236.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046626999.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046608888.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046623272.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046617765.1	12	Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_046622033.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046623655.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046618297.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046621277.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Hedgehog 'off' state";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_046629364.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046609850.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046611217.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046627016.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046620646.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046629258.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046611755.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046628767.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046604757.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_046619003.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_046615692.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603778.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046618441.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046615030.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_046605791.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_046624158.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-193048	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis"
XP_046618647.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_046623278.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046602988.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046608020.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046620289.1	4	MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_046624748.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046611943.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_046615308.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046630099.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046626996.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_046617064.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046609059.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046603207.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-6799198	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis"
XP_046606817.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046626778.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046629553.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046617848.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_046627928.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046604238.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046620960.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046615120.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046623579.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_046618931.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046621614.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648	"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046610702.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046609540.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046622518.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046608456.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046604685.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046604343.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046614799.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046624503.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046624074.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-3301854	"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly"
XP_046616877.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_046616798.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_046609844.1	5	MetaCyc: PWY-3841;MetaCyc: PWY-6614;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3	"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis"
XP_046620779.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046605810.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046609504.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_046611113.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_046629950.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_046618732.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046609117.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_046628547.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046623220.1	4	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_046610286.1	6	KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_046624557.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_046628485.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046611503.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046616652.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046624388.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046630069.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
XP_046625110.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_046604298.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046619447.1	60	KEGG: 00380+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-5789;MetaCyc: PWY-6945;Reactome: R-HSA-77288;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6946;Reactome: R-HSA-1482798;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00640+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7778;Reactome: R-HSA-77310;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7656;Reactome: R-HSA-77285;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6944;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6583	"Tryptophan metabolism";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Benzoate degradation";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Acyl chain remodeling of CL";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Propanoate metabolism";"Limonene and pinene degradation";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Glutaryl-coa degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Fatty acid degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid elongation";"Geraniol degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"2-methylpropene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Tryptophan metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Fatty acid salvage";"Toluene degradation";"Fatty acid degradation";"Androstenedione degradation";"beta-Alanine metabolism";"Pyruvate fermentation to butanol I"
XP_046623917.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_046614218.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-399719	"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Ion homeostasis";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors"
XP_046624419.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046615272.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_046603523.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624403.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046614371.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046607127.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148	"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046614591.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_046624137.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_046614871.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046612765.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Meiotic synapsis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046628561.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046610126.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046604030.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046606773.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-111465	"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins"
XP_046616504.1	7	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;MetaCyc: PWY-7255	"Glutathione synthesis and recycling";"Glutathione metabolism";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)"
XP_046619457.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046620178.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046604207.1	16	Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-2132295	"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"LDL clearance";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation"
XP_046613623.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046626537.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_046627411.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046626480.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046624468.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046629500.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046624668.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046613228.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_046629528.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046617856.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway"
XP_046611697.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046625513.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_046616498.1	33	Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885	"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins"
XP_046616219.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046605242.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046628883.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046624901.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046626740.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046622045.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8	"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism"
XP_046611528.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046622842.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046627310.1	9	MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-6703;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_046629138.1	14	MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-3781;Reactome: R-HSA-611105	"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport"
XP_046615326.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_046609548.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046620429.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046604938.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_046624193.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046626032.1	6	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism"
XP_046611975.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046618354.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046610402.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046609508.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_046614336.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_046610356.1	7	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_046625171.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046625368.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046610613.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046616831.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_046624954.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway"
XP_046619695.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_046615465.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046614350.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046612557.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046612327.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_046618566.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629275.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046613494.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046614454.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046623730.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_046620033.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046610585.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046623676.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"CD209 (DC-SIGN) signaling";"Attenuation phase";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_046612590.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046608505.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_046604568.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046621842.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112	"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification"
XP_046620261.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046620499.1	16	Reactome: R-HSA-5602498;Reactome: R-HSA-975110;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-1257604;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-1236974;Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-975871;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-6811558	"MyD88 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"PIP3 activates AKT signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"ER-Phagosome pathway";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046604507.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046623978.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046616614.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_046604506.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046627340.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046624344.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046603831.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609318.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903	"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Receptor Mediated Mitophagy"
XP_046628266.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_046615048.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046629835.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046626802.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046611949.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046622264.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046626091.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046604185.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046625848.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046620797.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_046604069.1	6	MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis"
XP_046612945.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_046622551.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046608695.1	31	MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5142;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-7663	"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)"
XP_046629213.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046628486.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_046628712.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_046614560.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046621343.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046617349.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046613478.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_046614063.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046626119.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046605704.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046604876.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046606064.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046619611.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_046624921.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7589	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_046629288.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046619537.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes"
XP_046609091.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_046623107.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046630277.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046616964.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046617820.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046606066.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046613865.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_046626797.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_046615651.1	12	MetaCyc: PWY-6527;Reactome: R-HSA-173599;MetaCyc: PWY-7343;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9	"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism"
XP_046615707.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046610252.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_046619063.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_046612703.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046622614.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046610202.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_046624672.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046604155.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046628285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046612970.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_046604529.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046622412.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408	"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation"
XP_046612769.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_046615794.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046620756.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046623857.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_046616335.1	5	KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046620291.1	7	KEGG: 00230+3.5.2.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7790;MetaCyc: PWY-5698;MetaCyc: PWY-5697;MetaCyc: PWY-7791	"Purine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis III"
XP_046602967.1	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_046620641.1	6	MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7442	"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis"
XP_046613358.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82	"Synthesis of PE";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism"
XP_046630535.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_046622881.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_046622649.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046625694.1	8	Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-196025	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions"
XP_046628497.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046624381.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046611547.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus"
XP_046627264.1	12	KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4	"Sulfur metabolism";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Monobactam biosynthesis";"Purine metabolism";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Assimilatory sulfate reduction III";"Purine metabolism"
XP_046627312.1	13	MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3	"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"One carbon pool by folate"
XP_046620752.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_046623762.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046620620.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_046606806.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_046624496.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046606845.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795	"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling"
XP_046605223.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046624106.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_046606254.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046618829.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_046606332.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_046620736.1	4	KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation"
XP_046623251.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046602854.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046611504.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_046604383.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MET activates PTK2 signaling"
XP_046622757.1	7	MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_046612914.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_046616077.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA"
XP_046617357.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046624902.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046615875.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_046617673.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046625850.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046617249.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046606530.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046624898.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_046630411.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046627334.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73980;Reactome: R-HSA-5601884;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-168325;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075	"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_046629487.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_046625544.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046608363.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_046612318.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_046612317.1	11	MetaCyc: PWY-6538;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-5695	"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation"
XP_046622005.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_046611142.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_046626648.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046626866.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046607634.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046629814.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24	"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"NOD1/2 Signaling Pathway";"p38MAPK events";"mTOR signaling pathway"
XP_046627038.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046604911.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_046630434.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_046610095.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046616105.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_046619631.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_046618832.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_046626626.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-1296072;Reactome: R-HSA-5576890	"Phase 2 - plateau phase";"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation"
XP_046627705.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046626133.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046629024.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046616365.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603220.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_046603559.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046614370.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046616499.1	33	Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways"
XP_046627145.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046617027.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_046618353.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046605189.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046605470.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-382556	"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of AXIN";"Interleukin-1 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"UCH proteinases";"ABC-family proteins mediated transport"
XP_046612439.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046621809.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046622101.1	7	Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-198323	"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol"
XP_046629813.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"mTOR signaling pathway";"DSCAM interactions";"NOD1/2 Signaling Pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_046618100.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046614174.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046620382.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046607748.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046617734.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046623309.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_046625582.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046619947.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046625571.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614177.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046617760.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046622098.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol"
XP_046612330.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER"
XP_046629518.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046611927.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046607214.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046613473.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_046613256.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046626522.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046617703.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046619252.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism"
XP_046616474.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046612900.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046624515.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_046617854.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046604439.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046614450.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_046608307.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627259.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046610922.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046616342.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_046611478.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_046629338.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046612638.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_046628466.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624387.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046607117.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_046619941.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins"
XP_046614181.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046625905.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046620262.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_046606750.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation"
XP_046620171.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_046617953.1	24	Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-418555	"Ca2+ pathway";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G-protein activation";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events"
XP_046628178.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation"
XP_046621666.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_046613441.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046620810.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_046613536.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_046605982.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_046615133.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_046604318.1	6	Reactome: R-HSA-8986944;Reactome: R-HSA-2892247;Reactome: R-HSA-6785807;Reactome: R-HSA-2892245;Reactome: R-HSA-452723;Reactome: R-HSA-3769402	"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation";"Interleukin-4 and Interleukin-13 signaling";"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional regulation of pluripotent stem cells";"Deactivation of the beta-catenin transactivating complex"
XP_046609245.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046613436.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_046612895.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046627436.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046613983.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046612237.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins"
XP_046629254.1	11	KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-6964	"Arginine biosynthesis";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II"
XP_046624347.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_046615249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046605879.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_046605284.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_046608638.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046623228.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046611798.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046615944.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046629817.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_046629912.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046604768.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_046626763.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-6798695;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813	"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Neutrophil degranulation";"G2/M Checkpoints";"Orc1 removal from chromatin";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids"
XP_046606820.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046614319.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046625175.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_046615914.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_046609401.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046629220.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_046626723.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-2197563	"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription"
XP_046618769.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046628917.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046605561.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046615069.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616513.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_046604575.1	4	Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
XP_046616671.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046624374.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046629885.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
XP_046622690.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046629640.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_046618183.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_046606851.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5469	"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis"
XP_046624680.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_046626198.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-380320	"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Gap junction assembly";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes"
XP_046622423.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_046608340.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046609578.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_046620834.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291	"HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C"
XP_046612652.1	9	Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046612819.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_046614525.1	6	MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_046623589.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046619781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046630413.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-9023661;Reactome: R-HSA-9018896;Reactome: R-HSA-2142691;Reactome: R-HSA-9020265;Reactome: R-HSA-9018676;Reactome: R-HSA-9018681	"Neutrophil degranulation";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of protectins"
XP_046628574.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046625167.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046614524.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_046607358.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_046611185.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_046616179.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046624875.1	13	MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_046620195.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046604227.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_046618115.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_046626121.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046619826.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_046605877.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_046607732.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609609.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_046629507.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046616026.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046623983.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046616120.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046620982.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_046612566.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_046611111.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_046603412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046622639.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_046611213.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_046630381.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046627430.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046620377.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046628676.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046620338.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_046606725.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046628196.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046627314.1	13	MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-5030	"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"L-histidine degradation III"
XP_046626175.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_046607275.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation"
XP_046629605.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046603910.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_046622465.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046626114.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046623443.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_046602944.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046620790.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046612435.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046623689.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046629508.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046630483.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046607710.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046605034.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_046609590.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_046607863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046623961.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046612764.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-1221632	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"Meiotic synapsis"
XP_046606465.1	7	Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_046607607.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585	"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence"
XP_046611692.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046603233.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046628078.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046605518.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046609490.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_046630149.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046629022.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits"
XP_046603742.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046619360.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_046612928.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046617069.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_046629603.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046623270.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046603204.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046603976.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_046606914.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_046608369.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046626276.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism"
XP_046619984.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_046604576.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
XP_046608373.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046620489.1	8	MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7193	"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I"
XP_046611680.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596	"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I"
XP_046611176.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Gap junction assembly";"Aggrephagy";"HCMV Early Events";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046623128.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046614849.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046627187.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046630511.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_046608241.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046611905.1	29	Reactome: R-HSA-5693565;Reactome: R-HSA-69541;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-6803204;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693579;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6803207	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Stabilization of p53";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Relaxin signaling pathway";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Thermogenesis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"PI3K-Akt signaling pathway";"Regulation of HSF1-mediated heat shock response";"Homologous DNA Pairing and Strand Exchange";"Human papillomavirus infection";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_046622448.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046623283.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046604845.1	7	MetaCyc: PWY-7841;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7839	"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis"
XP_046611243.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046627753.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_046616266.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753	"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions"
XP_046605051.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_046624278.1	39	Reactome: R-HSA-5654733;Reactome: R-HSA-190372;Reactome: R-HSA-5654732;Reactome: R-HSA-5654695;Reactome: R-HSA-5654727;Reactome: R-HSA-5654726;Reactome: R-HSA-2033514;Reactome: R-HSA-5655253;Reactome: R-HSA-5658623;Reactome: R-HSA-5655302;Reactome: R-HSA-5654704;Reactome: R-HSA-5654710;Reactome: R-HSA-2219530;Reactome: R-HSA-5654221;Reactome: R-HSA-5654699;Reactome: R-HSA-5673001;Reactome: R-HSA-5654719;Reactome: R-HSA-5654687;Reactome: R-HSA-2033519;Reactome: R-HSA-5654693;Reactome: R-HSA-190375;Reactome: R-HSA-5654712;Reactome: R-HSA-5654720;Reactome: R-HSA-190373;Reactome: R-HSA-190322;Reactome: R-HSA-5654688;Reactome: R-HSA-1839122;Reactome: R-HSA-5654689;Reactome: R-HSA-1839130;Reactome: R-HSA-6811558;Reactome: R-HSA-5654219;Reactome: R-HSA-109704;Reactome: R-HSA-5654700;Reactome: R-HSA-1257604;Reactome: R-HSA-8853338;Reactome: R-HSA-5654227;Reactome: R-HSA-5654228;Reactome: R-HSA-190371;Reactome: R-HSA-5654706	"Negative regulation of FGFR4 signaling";"FGFR3c ligand binding and activation";"Negative regulation of FGFR3 signaling";"PI-3K cascade:FGFR2";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR1 signaling";"FGFR3 mutant receptor activation";"Signaling by FGFR2 in disease";"FGFRL1 modulation of FGFR1 signaling";"Signaling by FGFR1 in disease";"SHC-mediated cascade:FGFR3";"PI-3K cascade:FGFR3";"Constitutive Signaling by Aberrant PI3K in Cancer";"Phospholipase C-mediated cascade, FGFR2";"SHC-mediated cascade:FGFR2";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR4";"Downstream signaling of activated FGFR1";"Activated point mutants of FGFR2";"FRS-mediated FGFR1 signaling";"FGFR2c ligand binding and activation";"FRS-mediated FGFR4 signaling";"PI-3K cascade:FGFR4";"FGFR1c ligand binding and activation";"FGFR4 ligand binding and activation";"SHC-mediated cascade:FGFR1";"Signaling by activated point mutants of FGFR1";"PI-3K cascade:FGFR1";"Signaling by activated point mutants of FGFR3";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Phospholipase C-mediated cascade: FGFR1";"PI3K Cascade";"FRS-mediated FGFR2 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR3 point mutants in cancer";"Phospholipase C-mediated cascade, FGFR3";"Phospholipase C-mediated cascade, FGFR4";"FGFR3b ligand binding and activation";"FRS-mediated FGFR3 signaling"
XP_046603644.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046623988.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046611490.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046615129.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046615511.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_046604756.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_046628153.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046607826.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046603948.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174154	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin"
XP_046612280.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_046625361.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046616312.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_046606844.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001	"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade"
XP_046604647.1	12	Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"G alpha (q) signalling events";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046615033.1	13	MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538	"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI"
XP_046613621.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046615964.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046608310.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046605853.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_046610610.1	14	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_046603084.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046621506.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_046604668.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046628571.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046609725.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_046614035.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046612259.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046618899.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046626995.1	7	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_046615663.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046611974.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_046602930.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_046610097.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_046604819.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046618404.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_046612958.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046613141.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_046603353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046624671.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_046606412.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_046610178.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397	"Galactose catabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_046613220.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046614361.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046613633.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046611127.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_046613767.1	11	Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046603188.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_046603061.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-8004	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I"
XP_046603217.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046627067.1	5	MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;Reactome: R-HSA-6798695	"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation"
XP_046611106.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617486.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_046629378.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_046607842.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_046618471.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046629015.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046607730.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046612852.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046623817.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046620948.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046627215.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol"
XP_046604359.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046612687.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627422.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_046604364.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046629048.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_046613517.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_046607703.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046623913.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_046620860.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619011.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046618147.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046625214.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046607318.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046627388.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_046622947.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046625233.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_046606732.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046619733.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046610259.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_046622521.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046605146.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046614449.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046624977.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046629174.1	6	MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12	"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis"
XP_046627671.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_046629734.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046613235.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_046622516.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046619762.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629785.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_046625197.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_046614248.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis"
XP_046624616.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046609807.1	10	MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I"
XP_046606404.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_046629281.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_046609839.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_046628463.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046629280.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046623127.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046603144.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_046626693.1	4	Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_046622418.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-203927	"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis"
XP_046612007.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_046616177.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046612303.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_046610378.1	7	MetaCyc: PWY-7282;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_046603565.1	6	KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism"
XP_046622754.1	22	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7727;MetaCyc: PWY-6598;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_046618948.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046613627.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046615346.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046623910.1	5	KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937	"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport"
XP_046625339.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046613911.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046630478.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_046609539.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046616339.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046604833.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_046607605.1	16	Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569	"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046604783.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046617397.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_046625909.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046604835.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046603642.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_046628172.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046629628.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046625562.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_046622899.1	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_046621102.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine metabolism"
XP_046616557.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_046613764.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046607319.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046617376.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046614187.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046630482.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_046611029.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_046606585.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_046629354.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046625668.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_046611686.1	12	Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13	"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism"
XP_046621766.1	25	Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-380270	"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Kinesins";"Aggrephagy";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes"
XP_046626919.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046618747.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_046617701.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046608386.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046630445.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_046625364.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046621219.1	5	MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;MetaCyc: PWY-5189	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_046605955.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046624084.1	1	Reactome: R-HSA-419771	"Opsins"
XP_046606267.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046623843.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046617675.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046628295.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_046622566.1	9	Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_046624620.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046609341.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_046619772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616910.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_046618160.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046616241.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_046613180.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046624981.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_046617389.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046606123.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_046616572.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046613264.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_046629646.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046617141.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_046630396.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-112382	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex"
XP_046625708.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_046604569.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_046614453.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_046617063.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046606633.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046628069.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-68827	"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"UCH proteinases";"Orc1 removal from chromatin";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex"
XP_046618425.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046603085.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046628030.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046626928.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046611133.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046622735.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046603406.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046617702.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046615241.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046611131.1	1	Reactome: R-HSA-201451	"Signaling by BMP"
XP_046622350.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046603877.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046627190.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046629629.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046613172.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046613286.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_046611105.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046620878.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608375.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_046615295.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_046615788.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046619640.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046610744.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_046610662.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_046617732.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_046618989.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046618355.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046606710.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_046609064.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046616611.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_046613265.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-8849473	"Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression"
XP_046621440.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046621577.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046616871.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_046622620.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_046602971.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_046621467.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046606314.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046607248.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046614347.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_046622349.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
XP_046622705.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_046606043.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046604395.1	12	MetaCyc: PWY-5132;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1	"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Propanoate metabolism"
XP_046617028.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_046615938.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046623285.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046604189.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046624375.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046619370.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046629798.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046621574.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046605945.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046614804.1	11	Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_046612369.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046612190.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_046603941.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_046617136.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046608292.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046626262.1	6	KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660517;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6368;MetaCyc: PWY-6580;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_046608499.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_046621700.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046617620.1	9	Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117	"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_046619841.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046607828.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046605232.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046625501.1	1	Reactome: R-HSA-5669034	"TNFs bind their physiological receptors"
XP_046626442.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046608036.1	7	MetaCyc: PWY-7158;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1	"L-phenylalanine degradation V";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_046604503.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046603995.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_046627342.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_046606753.1	16	KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6886	"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)"
XP_046622106.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046626566.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_046619119.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_046616990.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_046604078.1	17	Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5358606	"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046613584.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_046624849.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_046630463.1	13	MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)"
XP_046602904.1	13	Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-9014325	"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_046604361.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046617358.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_046603080.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_046610263.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046616278.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_046607633.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046627231.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046604004.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-432720	"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis"
XP_046611544.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046603977.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_046615068.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046613375.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046605564.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046616932.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046622897.1	18	MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_046607706.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046614260.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_046605225.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046620917.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_046614205.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_046607707.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046618451.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046623289.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_046618613.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_046606402.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046621412.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046622121.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046612235.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_046607415.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_046629721.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_046608451.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_046613731.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046618951.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046623092.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_046626157.1	18	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-166208	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"mTORC1-mediated signalling"
XP_046622624.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_046605205.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_046614921.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_046620366.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_046608308.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627640.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_046629556.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046624175.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046604795.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_046606222.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046604480.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603100.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046618949.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046603842.1	7	KEGG: 00620+2.3.3.9;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-7295;MetaCyc: PWY-7118;MetaCyc: PWY-7854	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV";"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_046607637.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_046628915.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046618428.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046604345.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046628708.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_046616971.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046623195.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_046609188.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_046612611.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_046610457.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_046624102.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_046608188.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_046620706.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046627126.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046614379.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Ion homeostasis";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_046626479.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046628096.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606048.1	5	KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_046622467.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046607038.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046603180.1	3	KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_046614622.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_046606223.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-390471	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046606007.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046608405.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046603182.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_046609614.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046623286.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046624881.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_046605950.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_046610267.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046614112.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_046612995.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy"
XP_046618310.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_046607940.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_046620857.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046613558.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_046616099.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046614477.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046623494.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046612844.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046620023.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046618116.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046627413.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_046623893.1	10	Reactome: R-HSA-69205;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-3841;MetaCyc: PWY-7184;MetaCyc: PWY-7199	"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage"
XP_046622914.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046626617.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
XP_046614851.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_046607468.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-111367	"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs"
XP_046623497.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_046607704.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_046607397.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046606906.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
XP_046628794.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_046620611.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081	"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"MET activates PTK2 signaling"
XP_046617253.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_046628263.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_046612782.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy"
XP_046628584.1	12	KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1	"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism"
XP_046610351.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_046617095.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624805.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046623287.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046606236.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046612851.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046618908.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046605760.1	7	Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_046604385.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_046604637.1	6	MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-6898;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine salvage IV (yeast)"
XP_046614083.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046603878.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046616898.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_046625612.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148	"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Aggrephagy";"Kinesins";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_046603924.1	17	Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-937042;Reactome: R-HSA-9645460	"Ub-specific processing proteases";"Downstream TCR signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway"
XP_046622050.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046607611.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046610468.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_046625382.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046618557.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_046617713.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_046606418.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046629372.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046611972.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_046618930.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_046628897.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046620327.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046604272.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_046602994.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046629870.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_046608291.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046612600.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046624844.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_046605631.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046618819.1	5	MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism"
XP_046623274.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046626109.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046607392.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_046625218.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_046615476.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_046626264.1	5	KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_046603879.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046624390.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046615209.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Neutrophil degranulation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_046624517.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_046613209.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_046621818.1	11	MetaCyc: PWY-6992;MetaCyc: PWY-7456;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-3881	"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis"
XP_046604104.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046630325.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046605848.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_046611906.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins"
XP_046625999.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046624469.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_046627790.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046620866.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046622663.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046624301.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046626544.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_046623713.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046626952.1	8	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-4551638	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins"
XP_046614169.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046628494.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_046610888.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_046614048.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614798.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_046625647.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_046610484.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_046605221.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046618956.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046612601.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046606692.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046611500.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046627441.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046608574.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_046620299.1	14	KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Butanoate metabolism";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_046608398.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_046610614.1	14	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5	"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism"
XP_046627322.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046615795.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046618658.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046607030.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_046607988.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_046614363.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism"
XP_046606472.1	7	Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2	"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism"
XP_046612959.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046614502.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN"
XP_046625112.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_046612545.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_046614533.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046624952.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046612667.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_046627797.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046617461.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046628122.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046606464.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046624547.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_046622134.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619814.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046606985.1	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11	"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway"
XP_046616355.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_046618897.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_046618895.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_046612356.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684	"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Activation of SMO";"Hedgehog 'on' state"
XP_046625672.1	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_046622107.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046617887.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
XP_046617130.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046624978.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_046612798.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins"
XP_046625515.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_046626336.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_046629167.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046627775.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046618651.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046627428.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_046624975.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046607803.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_046606070.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046611604.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy"
XP_046608892.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Gap junction assembly";"Aggrephagy";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events"
XP_046614046.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_046615459.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046623993.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046610494.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_046604156.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046620983.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046607823.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_046621607.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046606815.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046619685.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046620341.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_046606919.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_046619167.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046612193.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_046609678.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_046626625.1	3	Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072	"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels"
XP_046613238.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_046614637.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046625524.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046626001.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_046623778.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_046621860.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_046628763.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046608991.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_046619210.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_046608131.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046627992.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046612103.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_046625434.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046609380.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_046603150.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440	"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network"
XP_046602932.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_046609293.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046618764.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046629959.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046623507.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_046627193.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_046603803.1	4	MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
XP_046624401.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046613380.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046609275.1	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_046617395.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_046611796.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046627798.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046625183.1	9	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
XP_046616675.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046616969.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046613786.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046612668.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_046605145.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046611620.1	7	MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11	"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_046617648.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_046611753.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046614875.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_046624479.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_046606934.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_046618750.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046628798.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046622515.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_046606342.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_046608690.1	31	MetaCyc: PWY-5989;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-7723;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047	"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis"
XP_046608815.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_046604002.1	10	Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004	"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Negative regulation of MET activity"
XP_046617763.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_046605487.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_046609611.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046606262.1	25	Reactome: R-HSA-8951936;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8939245;Reactome: R-HSA-8931987;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8941858;Reactome: R-HSA-8941333;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-9018519;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8936459;Reactome: R-HSA-8941284;Reactome: R-HSA-8877330;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247	"RUNX3 regulates p14-ARF";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates chondrocyte maturation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling"
XP_046630450.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_046628638.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046608963.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046613348.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046605683.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901	"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol"
XP_046629550.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046618614.1	10	KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10	"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation"
XP_046628817.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Regulation of the apoptosome activity"
XP_046627037.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046626947.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046609135.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_046603989.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046627324.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046624348.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_046628947.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046624546.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046627039.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607400.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046629565.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046618358.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_046604336.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_046621638.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046608896.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046621401.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_046621613.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167238	"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation"
XP_046629418.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_046605954.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_046603352.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046609521.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_046622574.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_046626352.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046629803.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046606982.1	6	KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Neutrophil degranulation"
XP_046629357.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046614406.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948	"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants"
XP_046605796.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046620194.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046626356.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046611231.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046628423.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_046625250.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046613549.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_046620536.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046629178.1	6	MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-7442;Reactome: R-HSA-1474151	"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_046608133.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046604330.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046626128.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_046602996.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046614161.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_046604850.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046604663.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_046606706.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046609349.1	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_046620949.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_046629600.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046610891.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_046605499.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_046618606.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_046625641.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_046603143.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046615690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046619038.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_046627216.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_046622074.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046618311.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA"
XP_046616791.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_046628526.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_046612398.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046615679.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046607246.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_046611216.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046630231.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_046621052.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_046604689.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046621007.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_046628881.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_046614307.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046612352.1	16	Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-180585	"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G"
XP_046618337.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_046618876.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69656	"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin A:Cdk2-associated events at S phase entry"
XP_046630397.1	4	Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494	"Choline catabolism";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV"
XP_046620734.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_046629025.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_046619235.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_046620255.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603578.1	8	Reactome: R-HSA-70268;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Propanoate metabolism"
XP_046621765.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_046615328.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046622299.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_046629802.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_046603335.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_046613982.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046627245.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_046622884.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046624420.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_046627576.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_046617619.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142	"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_046610103.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_046627771.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_046626703.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_046629911.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_046625039.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-174184	"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_046607620.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_046612095.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046613303.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_046613849.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046603731.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_046620373.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046611376.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046618480.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_046614438.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046628716.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046609840.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046604342.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_046630376.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046615518.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_046630479.1	13	KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2160916	"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation"
XP_046616789.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046612442.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046610731.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_046608120.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046626627.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046610002.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_046603880.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046617859.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_046604519.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_046611691.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-1250347;Reactome: R-HSA-1236394;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1251985;Reactome: R-HSA-1963642;Reactome: R-HSA-1250342;Reactome: R-HSA-1963640;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604	"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB4 signaling";"Signaling by ERBB4";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling"
XP_046622670.1	15	Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246;Reactome: R-HSA-9665251;Reactome: R-HSA-9665250;Reactome: R-HSA-9665249;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-1236382	"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to afatinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"
XP_046619059.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_046624941.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046607612.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046624802.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046628800.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_046606444.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046630383.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_046613349.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046624890.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_046624159.1	5	Reactome: R-HSA-4755579;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_046616100.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046607095.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_046610991.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation"
XP_046613813.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_046614405.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046622919.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_046619208.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_046614638.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046620323.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_046606237.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-416482	"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events"
XP_046612441.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046612432.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_046605229.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046627530.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046623187.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046607647.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_046616382.1	4	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_046624450.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_046610620.1	14	KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417	"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_046621845.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_046604727.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_046613964.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046609113.1	4	Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046609765.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_046621363.1	10	KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_046606270.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism"
XP_046628435.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_046625194.1	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046625205.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046627801.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_046614897.1	12	KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-7233	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_046629027.1	6	MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10	"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes"
XP_046622678.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_046606445.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046618668.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_046608016.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046617161.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618007.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603856.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046620320.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_046612894.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046613475.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_046615937.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619008.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046615058.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847	"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones"
XP_046614065.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_046608012.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_046625342.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_046624171.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046607961.1	8	Reactome: R-HSA-8949664;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"Processing of SMDT1";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_046603653.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
XP_046613640.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_046626232.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046619437.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046614522.1	6	KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6364	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_046624566.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046611993.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_046629664.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation"
XP_046624513.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_046615480.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046616364.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046607616.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_046615571.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_046625526.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046619791.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046603853.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
XP_046625510.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046629958.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_046624665.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046624187.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_046615251.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046630489.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046605811.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046629362.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046608498.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_046630508.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_046607215.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_046610278.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_046624535.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046604154.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046623709.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046616113.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_046610580.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046605412.1	17	Reactome: R-HSA-69231;Reactome: R-HSA-2559585;Reactome: R-HSA-69202;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-6804114;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-69205	"Cyclin D associated events in G1";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription"
XP_046614693.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046623264.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046605554.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046624325.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_046629780.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_046622691.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_046623232.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_046603779.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046604889.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism"
XP_046604008.1	6	KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Starch degradation III";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_046614894.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046623977.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046624722.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046613357.1	7	MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7886	"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_046615858.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046629949.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_046625514.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_046618279.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_046612560.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046624923.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_046622129.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_046619416.1	13	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Macroautophagy";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation"
XP_046618010.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046615619.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633	"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046614086.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_046620988.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_046611085.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_046624223.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046622653.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046606442.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046621837.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway"
XP_046627707.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_046607953.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046610210.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_046603400.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046628468.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_046615043.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_046621337.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046606695.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_046621576.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)"
XP_046616379.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_046620166.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_046629786.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_046615215.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046627543.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_046620803.1	3	Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425	"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_046621384.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_046615512.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046614529.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_046606529.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_046615409.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_046615202.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_046628560.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_046628278.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_046603584.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046610412.1	5	Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)"
XP_046624402.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_046615851.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046606866.1	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_046626966.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046622394.1	11	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097	"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway"
XP_046618857.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606181.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648	"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes"
XP_046609382.1	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
XP_046628772.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046619698.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_046612481.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046629753.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_046613365.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_046603153.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432722	"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis"
XP_046623339.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046626405.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_046617617.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1	"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism"
XP_046603956.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046623820.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_046614557.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_046618883.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_046620705.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046605151.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
XP_046619585.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5678895;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-5689880;Reactome: R-HSA-9646399	"RHO GTPases regulate CFTR trafficking";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Ub-specific processing proteases";"Aggrephagy"
XP_046604305.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_046615618.1	8	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_046621813.1	11	MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-3881;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-6992;MetaCyc: PWY-7456;Reactome: R-HSA-4043916	"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_046624519.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046619868.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_046606143.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046606752.1	16	MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7218	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_046620376.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_046620144.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_046623981.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046606575.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_046630073.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046627860.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_046628405.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-6811558	"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_046604432.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_046616739.1	18	MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_046610588.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_046610284.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_046612971.1	7	KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;Reactome: R-HSA-9033241	"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Peroxisomal protein import"
XP_046626941.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_046620567.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_046606359.1	8	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_046616970.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_046626325.1	8	KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;Reactome: R-HSA-6791055	"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_046619358.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046627455.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_046614364.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895	"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_046616599.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046624389.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_046608073.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_046608226.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046607173.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_046617819.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046603296.1	31	MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-8049;MetaCyc: PWY-6113;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41	"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism"
XP_046618106.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_046607406.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_046620928.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046616388.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_046615297.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046605519.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_046620480.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_046608663.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_046603946.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-141430	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_046629543.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_046622655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_046613007.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_046628913.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_046616678.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046603410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046615680.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_046613828.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_046607247.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_046619385.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046607389.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_046613526.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_046620378.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_046613376.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_046614265.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions"
XP_046607542.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_046626189.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046610104.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_046625262.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-1855167;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6362;MetaCyc: PWY-6366;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159	"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism"
XP_046621941.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_046624429.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_046617808.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_046613139.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_046603886.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_046611016.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_046608040.1	7	KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;MetaCyc: PWY-7158	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"L-phenylalanine degradation V"
XP_046629827.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_046627457.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_046624062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_046614907.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_046603251.1	10	Reactome: R-HSA-977225;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;MetaCyc: PWY-7849;Reactome: R-HSA-975634	"Amyloid fiber formation";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Retinoid metabolism and transport"
XP_046613910.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_046606050.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046612457.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262	"TCF dependent signaling in response to WNT";"PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_046628151.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_046605792.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046624407.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Activation of RAC1";"mTOR signaling pathway"
XP_046611336.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_046623804.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_046620330.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_046620203.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_046626780.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046613344.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_046627961.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_046622282.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_046628821.1	6	Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-381033	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones"
XP_046612722.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_046619075.1	4	MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_046629642.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_046608014.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_046613971.1	19	Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5663220;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-182971	"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"RHO GTPases Activate Formins";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"EGFR downregulation"
XP_046617255.1	7	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039	"Synthesis of PG";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_046620647.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046619591.1	9	Reactome: R-HSA-9646399;Reactome: R-HSA-5689880;Reactome: R-HSA-5627083;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829	"Aggrephagy";"Ub-specific processing proteases";"RHO GTPases regulate CFTR trafficking";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Late endosomal microautophagy";"Chaperone Mediated Autophagy"
XP_046605471.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-211733	"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"G2/M Checkpoints";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_046607141.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_046626973.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_046621385.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046629745.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_046609237.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046627002.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_046620034.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_046629276.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_046617317.1	52	Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5687128	"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Downstream TCR signaling";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling"
XP_046621434.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_046615941.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046614476.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_046607608.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585	"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence"
XP_046621770.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_046625259.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_046608729.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_046608855.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_046619636.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_046615252.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046610181.1	10	Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-7328	"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
XP_046614674.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_046621595.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_046618725.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_046604299.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962	"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex"
XP_046616650.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046603381.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_046620701.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_046612726.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_046623196.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_046605987.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_046609804.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-6453	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis"
XP_046626111.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_046617759.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-166208	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling"
XP_046612917.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_046625284.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_046623010.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_046624887.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_046616648.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_046611445.1	14	MetaCyc: PWY-8052;Reactome: R-HSA-500657;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-399997	"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Acetylcholine regulates insulin secretion"
XP_046623249.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_046607385.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_046609774.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_046612550.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_046609273.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_046610847.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_046607603.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2"
XP_046607409.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046610581.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_046611126.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_046614823.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_046625769.1	5	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_046615166.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_046618632.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_046619805.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"DNA replication initiation"
XP_046622983.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_046622510.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046612480.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_046612899.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_046614084.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_046607989.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER"
XP_046625370.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_046610660.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046627150.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046606391.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_046628955.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_046603550.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_046622546.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_046623911.1	5	KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes"
XP_046612654.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)"
XP_046616337.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_046629747.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046603399.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046611425.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_046608098.1	13	MetaCyc: PWY-7039;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11	"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system"
XP_046611758.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_046622116.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_046616616.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997	"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion"
XP_046616366.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_046629537.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes"
XP_046603465.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_046626747.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_046604720.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_046630437.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_046603139.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_046618094.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_046625435.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_046605527.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_046609423.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_046618067.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046613144.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_046624846.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_046606992.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_046608425.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;MetaCyc: PWY-7822	"CS/DS degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)"
XP_046621405.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_046603402.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_046622472.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_046618867.1	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Recycling pathway of L1"
XP_046612023.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_046626225.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_046628840.1	6	Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426	"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_046622125.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_046616904.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_046618077.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_046620589.1	18	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482925	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PG"
XP_046610642.1	18	MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;Reactome: R-HSA-1482839	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Anandamide biosynthesis II";"Acyl chain remodelling of PE"
XP_046606315.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_046614315.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_046628879.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_046615267.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_046623061.1	15	Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604	"RET signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"PIP3 activates AKT signaling"
XP_046616075.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017	"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_046605991.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_046610424.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_046615381.1	13	MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5392	"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II"
XP_046603992.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_046613628.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_046606466.1	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_046606470.1	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_046605149.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_046617410.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events";"Oxidative Stress Induced Senescence"
XP_046607733.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_046626575.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"